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Volumn 186, Issue 9, 2002, Pages 1261-1269

A nontoxic chimeric enterotoxin adjuvant induces protective immunity in both mucosal and systemic compartments with reduced ige antibodies

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA TOXIN; ENTEROTOXIN; ESCHERICHIA COLI ENTEROTOXIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; INFLUENZA VACCINE; TETANUS TOXIN; TETANUS TOXOID;

EID: 0036838682     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/344526     Document Type: Article
Times cited : (56)

References (41)
  • 1
    • 0001328883 scopus 로고    scopus 로고
    • The mucosal immune system
    • Paul WE, ed. Philadelphia: Lippincott-Raven
    • McGhee JR, Kiyono H. The mucosal immune system. In: Paul WE, ed. Fundamental Immunology. 4th Ed. Philadelphia: Lippincott-Raven, 1999: 909-30.
    • (1999) Fundamental Immunology. 4th Ed. , pp. 909-930
    • McGhee, J.R.1    Kiyono, H.2
  • 2
    • 0035127224 scopus 로고    scopus 로고
    • Genetically manipulated bacterial toxin as a new generation mucosal adjuvant
    • Yamamoto M, McGhee JR, Hagiwara Y, Otake S, Kiyono H. Genetically manipulated bacterial toxin as a new generation mucosal adjuvant. Scand J Immunol 2001; 53:211-7.
    • (2001) Scand J Immunol , vol.53 , pp. 211-217
    • Yamamoto, M.1    McGhee, J.R.2    Hagiwara, Y.3    Otake, S.4    Kiyono, H.5
  • 3
    • 0026458260 scopus 로고
    • Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin
    • Spangler BD. Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol Rev 1992; 56:622-47.
    • (1992) Microbiol Rev , vol.56 , pp. 622-647
    • Spangler, B.D.1
  • 4
    • 0029805948 scopus 로고    scopus 로고
    • Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin
    • de Haan L, Verweij WR, Feil IK, et al. Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin. Infect Immun 1996; 64:5413-6.
    • (1996) Infect Immun , vol.64 , pp. 5413-5416
    • De Haan, L.1    Verweij, W.R.2    Feil, I.K.3
  • 5
    • 0028985871 scopus 로고
    • Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity
    • Dickinson BL, Clements JD. Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. Infect Immun 1995; 63:1617-23.
    • (1995) Infect Immun , vol.63 , pp. 1617-1623
    • Dickinson, B.L.1    Clements, J.D.2
  • 6
    • 0028918767 scopus 로고
    • Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants
    • Douce G, Turcotte C, Cropley I, et al. Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants. Proc Natl Acad Sci USA 1995; 92:1644-8.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1644-1648
    • Douce, G.1    Turcotte, C.2    Cropley, I.3
  • 7
    • 0029031840 scopus 로고
    • Construction of nontoxic derivatives of cholera toxin and characterization of the immunological response against the A subunit
    • Fontana MR, Manetti R, Giannelli V, et al. Construction of nontoxic derivatives of cholera toxin and characterization of the immunological response against the A subunit. Infect Immun 1995; 63:2356-60.
    • (1995) Infect Immun , vol.63 , pp. 2356-2360
    • Fontana, M.R.1    Manetti, R.2    Giannelli, V.3
  • 8
    • 0032489830 scopus 로고    scopus 로고
    • Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity
    • Giuliani MM, Del Giudice G, Giannelli V, et al. Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity. J Exp Med 1998; 187:1123-32.
    • (1998) J Exp Med , vol.187 , pp. 1123-1132
    • Giuliani, M.M.1    Del Giudice, G.2    Giannelli, V.3
  • 9
    • 0026699224 scopus 로고
    • The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity
    • Lycke N, Tsuji T, Holmgren J. The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity. Eur J Immunol 1992; 22:2277-81.
    • (1992) Eur J Immunol , vol.22 , pp. 2277-2281
    • Lycke, N.1    Tsuji, T.2    Holmgren, J.3
  • 10
    • 0027992673 scopus 로고
    • A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit
    • Pizza M, Fontana MR, Giuliani MM, et al. A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit. J Exp Med 1994; 180:2147-53.
    • (1994) J Exp Med , vol.180 , pp. 2147-2153
    • Pizza, M.1    Fontana, M.R.2    Giuliani, M.M.3
  • 11
    • 0030902280 scopus 로고    scopus 로고
    • Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrheagenicity but retain adjuvanticity
    • Yamamoto S, Takeda Y, Yamamoto M, et al. Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrheagenicity but retain adjuvanticity. J Exp Med 1997; 185:1203-10.
    • (1997) J Exp Med , vol.185 , pp. 1203-1210
    • Yamamoto, S.1    Takeda, Y.2    Yamamoto, M.3
  • 12
    • 0035282816 scopus 로고    scopus 로고
    • Protective immunity to Strepzococcus mutants induced by nasal vaccination with surface protein antigen and mutant cholera toxin adjuvant
    • Saito M, Otake S, Ohmura M, et al. Protective immunity to Strepzococcus mutants induced by nasal vaccination with surface protein antigen and mutant cholera toxin adjuvant. J Infect Dis 2001; 183:823-6.
    • (2001) J Infect Dis , vol.183 , pp. 823-826
    • Saito, M.1    Otake, S.2    Ohmura, M.3
  • 13
    • 0007205169 scopus 로고    scopus 로고
    • A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity
    • Yamamoto S, Kiyono H, Yamamoto M, et al. A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity. Proc Natl Acad Sci USA 1997; 94:5267-72.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 5267-5272
    • Yamamoto, S.1    Kiyono, H.2    Yamamoto, M.3
  • 15
    • 0033575433 scopus 로고    scopus 로고
    • Mutants of cholera toxin as an effective and safe adjuvant for nasal influenza vaccine
    • Hagiwara Y, Komase K, Chen Z, et al. Mutants of cholera toxin as an effective and safe adjuvant for nasal influenza vaccine. Vaccine 1999; 17: 2918-26.
    • (1999) Vaccine , vol.17 , pp. 2918-2926
    • Hagiwara, Y.1    Komase, K.2    Chen, Z.3
  • 16
    • 0018688158 scopus 로고
    • Cistrons encoding Escherichia coli heat-labile toxin
    • Dalls WS, Falkows S. Cistrons encoding Escherichia coli heat-labile toxin. J Bacteriol 1979; 139:850-5.
    • (1979) J Bacteriol , vol.139 , pp. 850-855
    • Dalls, W.S.1    Falkows, S.2
  • 17
    • 0025248414 scopus 로고
    • Conserved structures of cell wall protein genes among protein-producing Bacillus brevis strains
    • Ebisu S, Tsuboi A, Takagi H, et al. Conserved structures of cell wall protein genes among protein-producing Bacillus brevis strains. J Bacteriol 1990; 172:1312-20.
    • (1990) J Bacteriol , vol.172 , pp. 1312-1320
    • Ebisu, S.1    Tsuboi, A.2    Takagi, H.3
  • 18
    • 0001570799 scopus 로고
    • Genetic transformation of Bacillus brevis with plasmid DNA by electroporation
    • Takagi H, Kagiyama S, Kadowaki K, Tsukagoshi N, Udaka S. Genetic transformation of Bacillus brevis with plasmid DNA by electroporation. Agric Biol Chem 1989; 53:3099-105.
    • (1989) Agric Biol Chem , vol.53 , pp. 3099-3105
    • Takagi, H.1    Kagiyama, S.2    Kadowaki, K.3    Tsukagoshi, N.4    Udaka, S.5
  • 19
    • 0033217254 scopus 로고    scopus 로고
    • Structural conversion from nonnative to native form of recombinant human epidermal growth factor by Brevibacillus choshinensis
    • Miyauchi A, Ozawa M, Mizukami M, et al. Structural conversion from nonnative to native form of recombinant human epidermal growth factor by Brevibacillus choshinensis. Biosci Biotechnol Biochem 1999; 63:1965-9.
    • (1999) Biosci Biotechnol Biochem , vol.63 , pp. 1965-1969
    • Miyauchi, A.1    Ozawa, M.2    Mizukami, M.3
  • 20
    • 0033974741 scopus 로고    scopus 로고
    • A protein disulfide isomerase gene fusion expression system that increases the extracellular productivity of Bacillus brevis
    • Kajino T, Ohto C, Muramatsu M, et al. A protein disulfide isomerase gene fusion expression system that increases the extracellular productivity of Bacillus brevis. Appl Environ Microbiol 2000; 66:638-42.
    • (2000) Appl Environ Microbiol , vol.66 , pp. 638-642
    • Kajino, T.1    Ohto, C.2    Muramatsu, M.3
  • 21
    • 0028296259 scopus 로고
    • Simple method of purification of Escherichia coli heat-labile enterotoxin and cholera toxin using immobilized galactose
    • Uesaka Y, Otsuka Y, Lin Z, et al. Simple method of purification of Escherichia coli heat-labile enterotoxin and cholera toxin using immobilized galactose. Microb Pathog 1994; 16:71-6.
    • (1994) Microb Pathog , vol.16 , pp. 71-76
    • Uesaka, Y.1    Otsuka, Y.2    Lin, Z.3
  • 22
    • 0015359902 scopus 로고
    • Antitoxic immunity in experimental cholera: Comparison of immunity induced perorally and parenterally in mice
    • Fujita K, Finkelstein RA. Antitoxic immunity in experimental cholera: Comparison of immunity induced perorally and parenterally in mice. J Infect Dis 1972; 125:647-55.
    • (1972) J Infect Dis , vol.125 , pp. 647-655
    • Fujita, K.1    Finkelstein, R.A.2
  • 23
    • 0034327167 scopus 로고    scopus 로고
    • Cutting edge: The mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues
    • van Ginkel FW, Jackson RJ, Yuki Y, McGhee JR. Cutting edge: The mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues. J Immunol 2000; 165:4778-82.
    • (2000) J Immunol , vol.165 , pp. 4778-4782
    • Van Ginkel, F.W.1    Jackson, R.J.2    Yuki, Y.3    McGhee, J.R.4
  • 24
    • 0001925693 scopus 로고
    • Comparison of serologic and febrile responses in humans to vaccination with influenza A viruses or their hemagglutinin
    • Davenport FM, Hennessy AV, Brandon FM, Webster RG, Barrett CD, Lease GO. Comparison of serologic and febrile responses in humans to vaccination with influenza A viruses or their hemagglutinin. J Lab Clin Med 1964; 63:5-13.
    • (1964) J Lab Clin Med , vol.63 , pp. 5-13
    • Davenport, F.M.1    Hennessy, A.V.2    Brandon, F.M.3    Webster, R.G.4    Barrett, C.D.5    Lease, G.O.6
  • 25
    • 0026708950 scopus 로고
    • Cross-protection against influenza virus infection afforded by trivalent inactivated vaccines inoculated intranasally with cholera toxin B subunit
    • Tamura S, Ito Y, Asanuma H, et al. Cross-protection against influenza virus infection afforded by trivalent inactivated vaccines inoculated intranasally with cholera toxin B subunit. J Immunol 1992; 149:981-8.
    • (1992) J Immunol , vol.149 , pp. 981-988
    • Tamura, S.1    Ito, Y.2    Asanuma, H.3
  • 26
    • 0029935568 scopus 로고    scopus 로고
    • Acceleration of influenza virus clearance by Th1 cells in the nasal site of mice immunized intranasally with adjuvant-combined recombinant nucleoprotein
    • Tamura S, Miyata K, Matsuo K, et al. Acceleration of influenza virus clearance by Th1 cells in the nasal site of mice immunized intranasally with adjuvant-combined recombinant nucleoprotein. J Immunol 1996; 156: 3892-900.
    • (1996) J Immunol , vol.156 , pp. 3892-3900
    • Tamura, S.1    Miyata, K.2    Matsuo, K.3
  • 27
    • 0027453689 scopus 로고
    • Optimizing oral vaccines: Induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant
    • Jackson RJ, Fujihashi K, Xu-Amano J, Kiyono H, Elson CO, McGhee JR. Optimizing oral vaccines: Induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant. Infect Immun 1993; 61:4272-9.
    • (1993) Infect Immun , vol.61 , pp. 4272-4279
    • Jackson, R.J.1    Fujihashi, K.2    Xu-Amano, J.3    Kiyono, H.4    Elson, C.O.5    McGhee, J.R.6
  • 29
    • 0018950287 scopus 로고
    • Outcome of influenza infection: Effect of site of initial infection and heterotypic immunity
    • Yetter RA, Lehrer S, Ramphal R, Small PA Jr. Outcome of influenza infection: Effect of site of initial infection and heterotypic immunity. Infect Immun 1980; 29:654-62.
    • (1980) Infect Immun , vol.29 , pp. 654-662
    • Yetter, R.A.1    Lehrer, S.2    Ramphal, R.3    Small P.A., Jr.4
  • 30
    • 0016817506 scopus 로고
    • Permanent canine kidney (MDCK) cells for isolation and plaque assay of influenza B viruses
    • Tobita K. Permanent canine kidney (MDCK) cells for isolation and plaque assay of influenza B viruses. Med Microbiol Immunol (Berl) 1975; 162: 23-7.
    • (1975) Med Microbiol Immunol (Berl) , vol.162 , pp. 23-27
    • Tobita, K.1
  • 31
    • 0016801782 scopus 로고
    • Plaque assay and primary isolation of influenza A viruses in an established line of canine kidney cells (MDCK) in the presence of trypsin
    • Tobita K, Sugiura A, Enmote C, Furuyama M. Plaque assay and primary isolation of influenza A viruses in an established line of canine kidney cells (MDCK) in the presence of trypsin. Med Microbiol Immunol (Berl) 1975; 162:9-14.
    • (1975) Med Microbiol Immunol (Berl) , vol.162 , pp. 9-14
    • Tobita, K.1    Sugiura, A.2    Enmote, C.3    Furuyama, M.4
  • 32
    • 0015180180 scopus 로고
    • Toxigenic Escherichia coli in infantile diarrhea in Chicago
    • Gorbach SL, Khurana CM. Toxigenic Escherichia coli in infantile diarrhea in Chicago. J Lab Clin Med 1971; 78:981-2.
    • (1971) J Lab Clin Med , vol.78 , pp. 981-982
    • Gorbach, S.L.1    Khurana, C.M.2
  • 33
    • 84919581851 scopus 로고
    • An investigation of traveller's diarrhea
    • Rowe B, Taylor J, Bettelheim KA. An investigation of traveller's diarrhea. Lancet 1970; 1:1-5.
    • (1970) Lancet , vol.1 , pp. 1-5
    • Rowe, B.1    Taylor, J.2    Bettelheim, K.A.3
  • 35
    • 0030066516 scopus 로고    scopus 로고
    • Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant
    • Di Tommaso A, Saletti G, Pizza M, et al. Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant. Infect Immun 1996;64:974-9.
    • (1996) Infect Immun , vol.64 , pp. 974-979
    • Di Tommaso, A.1    Saletti, G.2    Pizza, M.3
  • 36
    • 0028839845 scopus 로고
    • IgE antibody to gelatin in children with immediate-type reactions to measles and mumps vaccines
    • Sakaguchi M, Ogura H, Inouye S. IgE antibody to gelatin in children with immediate-type reactions to measles and mumps vaccines. J Allergy Clin Immunol 1995;96:563-5.
    • (1995) J Allergy Clin Immunol , vol.96 , pp. 563-565
    • Sakaguchi, M.1    Ogura, H.2    Inouye, S.3
  • 37
    • 0027419489 scopus 로고
    • Anaphylaxis to measles, mumps, and rubella vaccine mediated by IgE to gelatin
    • Kelso JM, Jones RT, Yunginger JW. Anaphylaxis to measles, mumps, and rubella vaccine mediated by IgE to gelatin. J Allergy Clin Immunol 1993; 91:867-72.
    • (1993) J Allergy Clin Immunol , vol.91 , pp. 867-872
    • Kelso, J.M.1    Jones, R.T.2    Yunginger, J.W.3
  • 38
    • 0030795233 scopus 로고    scopus 로고
    • Gelatin-specific humoral and cellular immune responses in children with immediate- and nonimmediate-type reactions to live measles, mumps, rubella, and varicella vaccines
    • Kumagai T, Yamanaka T, Wataya Y, et al. Gelatin-specific humoral and cellular immune responses in children with immediate- and nonimmediate-type reactions to live measles, mumps, rubella, and varicella vaccines. J Allergy Clin Immunol 1997; 100:130-4.
    • (1997) J Allergy Clin Immunol , vol.100 , pp. 130-134
    • Kumagai, T.1    Yamanaka, T.2    Wataya, Y.3
  • 39
    • 0035825573 scopus 로고    scopus 로고
    • Effects of intranasal administration of cholera toxin (of Escherichia coli heat-labile enterotoxin) B sub-units supplemented with a trace amount of the holotoxin on the brain
    • Hagiwara Y, Iwasaki T, Asanuma H, et al. Effects of intranasal administration of cholera toxin (of Escherichia coli heat-labile enterotoxin) B sub-units supplemented with a trace amount of the holotoxin on the brain. Vaccine 2001; 19:1652-60.
    • (2001) Vaccine , vol.19 , pp. 1652-1660
    • Hagiwara, Y.1    Iwasaki, T.2    Asanuma, H.3
  • 40
    • 0024841499 scopus 로고
    • Bacillus brevis, a host bacterium for efficient extracellular production of useful proteins
    • Udaka S, Tsukagoshi N, Yamagata H. Bacillus brevis, a host bacterium for efficient extracellular production of useful proteins. Biotechnol Genet Eng Rev 1989;7:113-46.
    • (1989) Biotechnol Genet Eng Rev , vol.7 , pp. 113-146
    • Udaka, S.1    Tsukagoshi, N.2    Yamagata, H.3
  • 41
    • 0027297667 scopus 로고
    • High-level secretion of heterologous proteins by Bacillus brevis
    • Udaka S, Yamagata H. High-level secretion of heterologous proteins by Bacillus brevis. Methods Enzymol 1993; 217:23-33.
    • (1993) Methods Enzymol , vol.217 , pp. 23-33
    • Udaka, S.1    Yamagata, H.2


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