In vitro sensitization of human bronchus by β2-adrenergic agonists

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 283, Issue 5 27-5, 2002, Pages

  Faisy, Christophe ^a,b   Naline, Emmanuel ^a,b   Diehl, Jean Luc ^a,b   Emonds Alt, Xavier ^a,b   Chinet, Thierry ^a,b   Advenier, Charles ^a,b,c  

^a UPRES EA 220   (France)

^b HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^c SANOFI   (France)

Author keywords

Airway sensitization; Airway smooth muscle; Asthma; Endothelin 1

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCHOLINE; ADENYLATE CYCLASE ACTIVATOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRADYKININ; BRADYKININ B2 RECEPTOR ANTAGONIST; CALPHOSTIN C; DEXAMETHASONE; ENDOTHELIN 1; FENOTEROL; FORSKOLIN; GLIOTOXIN; I KAPPA B; ICATIBANT; INDOMETACIN; LEUKOTRIENE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MONTELUKAST; NOLPITANTIUM; OSANETANT; PROSTAGLANDIN SYNTHASE INHIBITOR; PROSTANOID; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; SAREDUTANT; TACHYKININ; TACHYKININ RECEPTOR ANTAGONIST; VAPIPROST;

ADULT; AGED; ARTICLE; ASTHMA; BRONCHOSPASM; BRONCHUS REACTIVITY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SENSITIZATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTION;

EID: 0036838356     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00063.2002     Document Type: Article

References (62)

1. Adcock IM. Role of transcription factors in mediating cytokine-induced inflammation. Eur Respir J 10: 289-293, 2000.
2. Anderson GP. Interactions between corticosteroids and β-adrenergic agonists in asthma disease induction, progression, and exacerbation. Am J Respir Crit Care Med 161: S188-S196, 2000.
3. Baraniuk JN, Molet S, Mullol J, and Naranch K. Endothelins and the airway mucosa. Pulm Pharmacol Ther 11: 113-123, 1998.
4. 11] substance P in isolated human bronchi. Eur J Pharmacol 379: 87-95, 1999.
5. Barman SA. Effect of protein kinase C on hypoxic pulmonary vasoconstriction. Am J Physiol Lung Cell Mol Physiol 280: L888-L895, 2001.
6. Barnes PJ. Pharmacology of airway smooth muscle. Am J Respir Crit Care Med 158: S123-S132, 1998.
7. 2-agonists in asthma. Trends Pharmacol Sci 13: 20-23, 1992.
8. Bertrand C, Naline E, and Advenier C. In vitro effects of the endothelins on airway and vascular smooth muscle tone. In: Pulmonary Actions of the Endothelins. Basel: Birkhäuser Verlag, 1999, p. 107-123.
9. Börch-Haubold AG, Pasquet S, and Watson SP. Direct inhibition of cylooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059. J Biol Chem 273: 28766-28772, 1998.
10. Bousquet J, Jeffery PK, Busse WW, Jonhson M, and Vignola AM. Asthma. From bronchoconstriction to airways inflammation and remodeling. Am J Respir Crit Care Med 161: 1720-1745, 2000.
11. Buchheit KH, Hofman A, and Fozard JR. Salbutamol-induced airway hyperreactivity in guinea pigs is not due to a loss of its bronchodilator effects. Eur J Pharmacol 287: 85-88, 1995.
12. Carlin S, Poronnik P, Coock DI, Carpenter L, Biden TJ, Johnson PRA, and Black JL. An antisense of protein kinase C-ζ inhibits proliferation of human airway smooth muscle cells. Am J Respir Cell Mol Biol 23: 555-559, 2000.
13. Christman JW, Sadikot RT, and Blackwell TS. The role of nuclear factor-KB in pulmonary diseases. Chest 117: 1482-1487, 2000.
14. Crane J, Pearce N, Flatt A, Burgess C, Jackson R, Kwong T, Ball M, and Beasley R. Prescribed fenoterol and death from asthma in New Zealand, 1981-83: Case control study. Lancet 8644: 917-922, 1989.
15. Davis RJ. MAPKs: New JNK expands the group. Trends Biochem Sci 19: 470-473, 1994.
16. 2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells. J Biol Chem 274: 1005-1010, 1999.
17. Fernandes LB, Henry PJ, and Goldie RG. Endothelin-1 potentiates cholinergic nerve-mediated contraction in human isolated bronchus. Eur Respir J 14: 439-442, 1999.
18. Flanagan RJ. Guidelines for the interpretation of analytical toxicology results and unit of measurement conversion factor. Ann Clin Biochem 35: 261-267, 1998.
19. Frossard N, Naline E, Olgart C, Mathieu E, Edmonds-Alt X, and Advenier C. Increased production of NGF by IL-1β in the human bronchus in vitro is related to bronchial hyperresponsiveness. Effects of SR 142801 (Abstract). Am J Respir Crit Care Med 163: A55, 2001.
20. Gao Y, Tang S, Zhou S, and Ware JA. The thromboxane A2 receptor activates mitogen-activated protein kinase via protein kinase C-dependent Gi coupling and Src-dependent phosphorylation of the epidermal growth factor receptor. J Pharmacol Exp Ther 296: 426-433, 2001.
21. Goldie RG. Endothelin receptor subtypes: Distribution and function in the lung. Pulm Pharmacol Ther 11: 89-95, 1998.
22. Goldie RG. Endothelins in health and disease: An overview. Clin Exp Pharmacol Physiol 26: 145-148, 1999.
23. 2 receptor expression and function by inflammatory insults. Eur Respir J 10: 276-279, 2000.
24. Hallsworth MP, Moir LM, Lai D, and Hirst SJ. Inhibitors of mitogen-activated protein kinases differentially regulate eosinophil-activating cytokine release from human airway smooth muscle. Am J Respir Crit Care Med 164: 688-697, 2001.
25. Hay DW. Endothelins. In: Airways Smooth Muscle: Peptides Receptors, Ions Channels and Signal Transduction. Basel: Birkhäuser Verlag, 1995, p. 1-50.
26. Hay DW. Endothelin-1: An interesting peptide or an important mediator in pulmonary diseases? Pulm Pharmacol Ther 11: 141-146, 1998.
27. Hay DW. Putative mediator role of endothelin-1 in asthma and other lung diseases. Clin Exp Pharmacol Physiol 26: 168-171, 1999.
28. Hay DW, Thorphy TJ, and Undem BJ. Cysteinyl leukotrienes in asthma: Old mediators up to new tricks. Trends Pharmacol Sci 16:304-309, 1995.
29. Hayashi R, Yamashita N, Matsui S, Fujita T, Araya J, Kassa K, Arai N, Yoshida Y, Kashii T, Maruyama M, Sugiyama E, and Kobayashi M. Bradykinin stimulates IL-6 and IL-8 production by human lung fibroblasts through ERK- and p38 MAPK-dependent mechanisms. Eur Respir J 16: 452-458, 2000.
30. Hedges JC, Yamboliev IA, Ngo M, Horowitz B, Adam LP, and Gerthoffer WT. p38 mitogen-activated protein kinase expression and activation in smooth muscle. Am J Physiol Cell Physiol 275: C527-C534, 1998.
31. Henry PJ. Endothelin receptor distribution and function in the airways. Clin Exp Pharmacol Physiol 26: 162-167, 1999.
32. Hirst SJ, Walker TR, and Chilvers ER. Phenotypic diversity and molecular mechanisms of airway smooth muscle proliferation in asthma. Eur Respir J 16: 159-177, 2000.
33. Jaffuel D, Demoly P, Gougat C, Balaguer P, Mautino G, Godard P, Bousquet J, and Mathieu M. Transcriptional potencies of inhaled glucocorticoids. Am J Respir Crit Care Med 162: 57-63, 2000.
34. 11] substance P acts as a biased agonist toward neuropeptide and chemokine receptors. J Biol Chem 273: 3097-3104, 1998.
35. 2-adrenergic and tachykinin neurokinin-2 receptors. J Allergy Clin Immunol 106: S104-S108, 2000.
36. 2-Adrenoceptor agonist-induced upregulation of tachykinin NK2 receptor expression and function in airway smooth muscle. Am J Respir Cell Mol Biol 21: 409-417, 1999.
37. Kips JC and Pauwels RA. Long-acting inhaled β2-agonist therapy in asthma. Am J Respir Crit Care Med 164: 923-932, 2001.
38. ERK2) in airway smooth muscle (Abstract). Am J Respir Crit Care Med 161: A450, 2000.
39. Korn HS, Jerre A, and Brattsand R. Effect of formoterol and budesonid on GM-CSF and IL-8 secretion by triggered human bronchial epithelial cells. Eur Respir J 17: 1070-1077, 2001.
40. Lecaillon JB, Kaiser G, Palmisano M, Morgan J, and Della Cioppa G. Pharmacokinetics and tolerability of formoterol in healthy volunteers after a single high dose of Foradil dry powder inhalation via aerosolizer. Eur J Clin Pharmacol 55: 131-138, 1999.
41. Michaël JR and Markewitz BA. Endothelins and the lung. Am J Respir Crit Care Med 154: 555-581, 1996.
42. Morley L, Sanjar S, and Newth C.Viewpoint: untoward effects of β-adrenoreceptor agonists in asthma. Eur Respir J 3: 226-233, 1990.
43. Myers A and Undem BJ. Electrophysiological effects of tachykinins and capsaicin on guinea-pig parasympathetic ganglion neurons. J Physiol 470: 665-679, 1993.
44. Naline E, Bertrand C, Biyah K, Fujitani Y, Okada T, Bisson A, and Advenier C. Modulation of ET-1-induced contraction of human bronchi by airway epithelium-dependent nitric oxide release via ETA receptor activation. Br J Pharmacol 126: 529-535, 1999.
45. Naline E, Zhang Y, Qian Y, Mairon N, Anderson GP, Grandordy B, and Advenier C. Relaxant effects and duration of action of formoterol and salmeterol on the isolated bronchus. Eur Respir J 7: 914-920, 1994.
46. Panettieri RA. Cellular and molecular mechanisms regulating airway smooth muscle proliferation and cell adhesion molecule expression. Am J Respir Crit Care Med 158: S133-S140, 1998.
47. Peters MJ, Adcock IM, Brown CR, and Barnes PJ. β-adrenoceptor agonists interfere with glucocorticoid receptor DNA binding in rat lung. Eur J Pharmacol 289: 275-281, 1995.
48. Peters-Golden M and Brock TG. Intracellular compartmentalization of leukotriene biosynthesis. Am J Respir Crit Care Med 161: S36-S40, 2000.
49. Ricciardolo FL, Nadel JA, GrafPD, Bertrand C,Yoshihara S, and Geppetti P. Role of kinins in anaphylactic-induced bronchoconstriction mediated by tachykinins in guinea-pigs. Br J Pharmacol 113: 508-512, 1994.
50. Roland M, Bhowmick A, Sapsford RJ, Seemungal TA, Jeffries DJ, Warner TD, and Wedzicha JA. Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease. Thorax 56: 30-35, 2001.
51. Salmeron S, Brochard L, Mal H, Tenaillon A, Henry-Amar M, Renon D, Duroux P, and Simonneau G. Nebulized vs. intravenous albuterol in hypercapnic acute asthma. A multicenter, double-blind, randomized study. Am J Respir Crit Care Med 149: 1466-1470, 1994.
52. 3 receptor antagonists (Abstract). Am J Respir Crit Care Med 161: A437, 2000.
53. Schmidlin F, Landry Y, and Gies JP. Regulation of bradykinin B2 receptor expression. Eur Respir Rev 10: 274-275, 2000.
54. Schmidt D and Rabe KL. The role of leukotrienes in the regulation of tone and responsiveness in isolated human airways. Am J Respir Crit Care Med 161: S62-S67, 2000.
55. Sears MR. Deleterious effects of inhaled β-agonists. Chest 119: 1297-1299, 2001.
56. 2-adrenoceptor polymorphism. Thorax 55: 762-776, 2000.
57. Touqui L. Regulation of pulmonary synthesis of type II secretory phospholipase A2 and potential role in acute lung inflammation. Eur Respir Rev 10: 286-288, 2000.
58. Underwood DC, Osborn RR, Kotzer CJ, Adams JL, Lee JC, Webb EF, Carpenter DC, Bochnowicz S, Thomas HC, Hay DW, and Griswold DE. SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence. J Pharmacol Exp Ther 293:281-288, 2000.
59. Van Schayck CP, Graasma SJ, Visch MB, Dompelling E, Van Weel C, and Van Herwaarden CL. Increased bronchial hyperresponsiveness after inhaling salbutamol during one year is not caused by subsensitization to salbutamol. J Allergy Clin Immunol 86: 783-790, 1990.
60. Wang ZL, Bramley AM, McNamara A, Paré PD, and Bai TR. Chronic fenoterol exposure increases in vivo and in vitro airway responses in guinea pigs. Am JRespir Crit Care Med 149: 960-965, 1994
61. Webb BLJ, Hirst SJ, and Giembycz MA.Protein kinase C isoenzymes: A review of their structure, regulation and role in airways smooth muscle tone and mitogenesis. Br J Pharmacol 130:1433-1452, 2000.
62. Wilson SJ, Wallin A, Della-Cioppa G, Sandströn T, and Holgate ST. Effects of budesonide and formoterol on NF-KB, adhesion molecules, and cytokines in asthma. Am J Respir Crit Care Med 164: 1047-1052, 2001.