Investigation of the role of lipoxygenase in bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung

Chemical Research in Toxicology

Volumn 15, Issue 10, 2002, Pages 1267-1273

  Bedard, Leanne L ^a   Smith, Graeme B J ^a   Reid, Ken R ^a   Petsikas, Dimitri ^a   Massey, Thomas E ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINOBENZOTRIAZOLE; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANOL; ARACHIDONIC ACID; CARBENE; CARCINOGEN; CONCANAMYCIN A; CYTOCHROME P450; HEMOGLOBIN; HORSERADISH PEROXIDASE; LIPOXYGENASE; MYELOPEROXIDASE; NORDIHYDROGUAIARETIC ACID; OXOACID; OXYGENASE; PEROXIDASE;

ADULT; AFFINITY CHROMATOGRAPHY; AGED; ARTICLE; CATALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN TISSUE; HYDROXYLATION; LUNG TOXICITY; MALE; PATHOGENESIS; REACTION ANALYSIS; SIGNAL TRANSDUCTION; SOYBEAN; TOBACCO;

AGED; BIOTRANSFORMATION; CARCINOGENS; CYTOSOL; FEMALE; HEMOGLOBINS; HUMANS; HYDROXYLATION; LIPOXYGENASE; LUNG; LUNG NEOPLASMS; MALE; MIDDLE AGED; NITROSAMINES; SMOKING;

ARMORACIA RUSTICANA; GLYCINE MAX; NICOTIANA TABACUM;

EID: 0036802396     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx025524m     Document Type: Article

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