Recent studies on mechanisms of bioactivation and detoxification of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen

Critical Reviews in Toxicology

Volumn 26, Issue 2, 1996, Pages 163-181

  Hecht, Stephen S ^a  

^a AMERICAN HEALTH FOUNDATION   (United States)

Author keywords

06 methylguanine; 4 (Methylnitrosamino) 1 (3 pyridyl) 1 butanone; Cytochromes; DNA adducts; DNA methylation; DNA pyridyloxobutylation; Glucuronidation; Hemoglobin adducts; K ras oncogenes; Lung carcinogenesis; Metabolic activation; P450

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE;

DETOXIFICATION; DNA ADDUCT; DNA METHYLATION; GLUCURONIDATION; HUMAN; LUNG CANCER; LUNG CARCINOGENESIS; METABOLIC ACTIVATION; MUTATION; NONHUMAN; ONCOGENE; REVIEW; SMOKING;

ANIMALIA; NICOTIANA TABACUM; PRIMATES; RODENTIA;

EID: 0029897806     PISSN: 10408444     EISSN: None     Source Type: Journal    
DOI: 10.3109/10408449609017929     Document Type: Review

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