Biotransformation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in freshly isolated human lung cells

Carcinogenesis

Volumn 20, Issue 9, 1999, Pages 1809-1818

  Smith, Graeme B J ^a   Castonguay, Andre ^b   Donnelly, Patty J ^a   Reid, Ken R ^a   Petsikas, Dimitri ^a   Massey, Thomas E ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; CARBON; CARBONYL DERIVATIVE; CARCINOGEN; CYTOCHROME P450; NITROSAMINE; OXOACID; PROADIFEN; PYRIDINE DERIVATIVE; RADIOACTIVE MATERIAL; TRITIUM;

ADULT; AGED; ARTICLE; BIOTRANSFORMATION; CLINICAL ARTICLE; DETOXIFICATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROXYLATION; LOBECTOMY; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS MACROPHAGE; LUNG CARCINOGENESIS; MALE; METABOLIC ACTIVATION; METABOLISM; METABOLITE; OXIDATION; PRIORITY JOURNAL; RADIOACTIVITY; REDUCTION; STATISTICAL ANALYSIS; TOBACCO;

AGED; BIOTRANSFORMATION; CARCINOGENS; FEMALE; HUMANS; HYDROXYLATION; LUNG; LUNG NEOPLASMS; MACROPHAGES, ALVEOLAR; MALE; METABOLIC DETOXICATION, DRUG; MIDDLE AGED; NITROSAMINES; OXIDATION-REDUCTION; PROADIFEN; PULMONARY ALVEOLI;

EID: 0032824052     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.9.1809     Document Type: Article

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