-
1
-
-
0025093973
-
Vascular attack as a therapeutic strategy for cancer
-
Denekamp J. Vascular attack as a therapeutic strategy for cancer Cancer Metastasis Rev. 9(3), 267-282 (1990).
-
(1990)
Cancer Metastasis Rev
, vol.9
, Issue.3
, pp. 267-282
-
-
Denekamp, J.1
-
2
-
-
0028028308
-
Angiogenesis inhibition: A review
-
Auerbach W, Auerbach P, Angiogenesis inhibition: a review. Pharmacol. Ther. 63, 265-311 (1994).
-
(1994)
Pharmacol. Ther
, vol.63
, pp. 265-311
-
-
Auerbach, W.1
Auerbach, P.2
-
3
-
-
0026100365
-
Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids
-
Rewcastle GW, Atwell GJ, Zhuang I, Baguley BC, Denny WA. Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids. J. Med. Chem. 34(1), 217-222 (1991).
-
(1991)
J. Med. Chem
, vol.34
, Issue.1
, pp. 217-222
-
-
Rewcastle, G.W.1
Atwell, G.J.2
Zhuang, I.3
Baguley, B.C.4
Denny, W.A.5
-
4
-
-
0000677063
-
Impact on tumour perfusion measured by dynamic magnetic resonance imaging (MRI), in the Phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
-
Rustin G, Galbraith S, Taylor N et al. Impact on tumour perfusion measured by dynamic magnetic resonance imaging (MRI), in the Phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Ann. Oncol. 9, 126 (1998).
-
(1998)
Ann. Oncol
, vol.9
, pp. 126
-
-
Rustin, G.1
Galbraith, S.2
Taylor, N.3
-
5
-
-
0000226885
-
Phase I pharmacokinetic and pharmacodynamic study of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent
-
Jameson MB, Thompson PI, Baguley BC et al. Phase I pharmacokinetic and pharmacodynamic study of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent. Proc. Am. Soc. Clin. Oncol. 19, 182a (2000).
-
(2000)
Proc. Am. Soc. Clin. Oncol
, vol.19
-
-
Jameson, M.B.1
Thompson, P.I.2
Baguley, B.C.3
-
6
-
-
0026602628
-
Coley's toxins in perspective
-
Starnes CO. Coley's toxins in perspective. Nature 357, 11-12 (1992).
-
(1992)
Nature
, vol.357
, pp. 11-12
-
-
Starnes, C.O.1
-
7
-
-
0034754259
-
Fever and cancer in perspective
-
Hobohm U. Fever and cancer in perspective. Cancer Immunol. Immunother. 50, 391-396 (2001).
-
(2001)
Cancer Immunol. Immunother
, vol.50
, pp. 391-396
-
-
Hobohm, U.1
-
8
-
-
0022369998
-
Tumor necrosis factor (TNF)
-
Old LJ. Tumor necrosis factor (TNF). Science 230, 630-632 (1985).
-
(1985)
Science
, vol.230
, pp. 630-632
-
-
Old, L.J.1
-
9
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
Carswell EA, Old LJ, Kassel RL, Green S, Fiore N, Williamson B. An endotoxin-induced serum factor that causes necrosis of tumors. Proc. Natl Acad. Sci. USA 25, 3666-3670 (1975).
-
(1975)
Proc. Natl. Acad. Sci. USA
, vol.25
, pp. 3666-3670
-
-
Carswell, E.A.1
Old, L.J.2
Kassel, R.L.3
Green, S.4
Fiore, N.5
Williamson, B.6
-
10
-
-
0026531756
-
High-dose recombinant tumor necrosis factor-α in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma
-
Lienard D, Ewalenko P, Delmotte P, Renard JJ, Lejeune F. High-dose recombinant tumor necrosis factor-α in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma. J. Clin. Oncol. 10, 52-60 (1992).
-
(1992)
J. Clin. Oncol
, vol.10
, pp. 52-60
-
-
Lienard, D.1
Ewalenko, P.2
Delmotte, P.3
Renard, J.J.4
Lejeune, F.5
-
11
-
-
0022640318
-
Endotoxin-mediated necrosis and regression of established tumours in die mouse. A corrlative study of quantitative changes in blood flow and morphology
-
MacPherson GG, Niorth RJ. Endotoxin-mediated necrosis and regression of established tumours in die mouse. A corrlative study of quantitative changes in blood flow and morphology. Cancer Immunol. Immunother 21(3), 209-216 (1986).
-
(1986)
Cancer Immunol. Immunother
, vol.21
, Issue.3
, pp. 209-216
-
-
MacPherson, G.G.1
Niorth, R.J.2
-
12
-
-
0026038527
-
Influence of recombinant tumour necrosis factor-α on blood flow and antibody localisation in human tumour xenografts in nude mice
-
Pimm MV, Gribben SJ, Morris TM. Influence of recombinant tumour necrosis factor-α on blood flow and antibody localisation in human tumour xenografts in nude mice. J. Cancer Res. Clin. Oncol. 117(6), 543-548 (1991).
-
(1991)
J. Cancer Res. Clin. Oncol
, vol.117
, Issue.6
, pp. 543-548
-
-
Pimm, M.V.1
Gribben, S.J.2
Morris, T.M.3
-
13
-
-
0023215827
-
Flavone acetic acid (NSC 347512) induces haemorrhagic necrosis of mouse colon 26 and 38 tumours
-
Smith GP, Calveley SB, Smith MJ, Baguley BC. Flavone acetic acid (NSC 347512) induces haemorrhagic necrosis of mouse colon 26 and 38 tumours. Eur. J. Cancer Clin. Oncol. 23, 1209-1212 (1987).
-
(1987)
Eur. J. Cancer Clin. Oncol
, vol.23
, pp. 1209-1212
-
-
Smith, G.P.1
Calveley, S.B.2
Smith, M.J.3
Baguley, B.C.4
-
14
-
-
0024571314
-
Comparison of the effects of flavone acetic acid, fostriecin, homoharringtonine and tumour necrosis factor-a on Colon 38 tumors in mice
-
Baguley BC, Calveley SB, Crowe KK, Fray LM, O'Rourke SA, Smith GP. Comparison of the effects of flavone acetic acid, fostriecin, homoharringtonine and tumour necrosis factor-a on Colon 38 tumors in mice. Eur. J. Cancer Clin. Oncol. 25, 263-269 (1989).
-
(1989)
Eur. J. Cancer Clin. Oncol
, vol.25
, pp. 263-269
-
-
Baguley, B.C.1
Calveley, S.B.2
Crowe, K.K.3
Fray, L.M.4
O'Rourke, S.A.5
Smith, G.P.6
-
15
-
-
0022589148
-
Flavone acetic acid: A novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice
-
Plowman J, Narayanan VL, Dykes D et al. Flavone acetic acid. a novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice. Cancer Treat. Rep. 70, 631-638 (1986).
-
(1986)
Cancer Treat. Rep
, vol.70
, pp. 631-638
-
-
Plowman, J.1
Narayanan, V.L.2
Dykes, D.3
-
16
-
-
0023809013
-
Flavone acetic add (NSC 347512)-induced modulation of murine tumor physiology monitored by in vivo nuclear magnetic resonance spectroscopy
-
Evelhoch JL, Bissery M-C, Chabot GG et al. Flavone acetic add (NSC 347512)-induced modulation of murine tumor physiology monitored by in vivo nuclear magnetic resonance spectroscopy. Cancer Res. 48, 4749-4755 (1988).
-
(1988)
Cancer Res
, vol.48
, pp. 4749-4755
-
-
Evelhoch, J.L.1
Bissery, M.-C.2
Chabot, G.G.3
-
17
-
-
0024335180
-
Blood flow failure as a major determinant in the antitumor action of flavone acetic acid (NSC 347512)
-
Zwi LJ, Baguley BC, Gavin JB, Wilson WR. Blood flow failure as a major determinant in the antitumor action of flavone acetic acid (NSC 347512). J. Natl Cancer Inst. 81, 1005-1013 (1989).
-
(1989)
J. Natl. Cancer Inst
, vol.81
, pp. 1005-1013
-
-
Zwi, L.J.1
Baguley, B.C.2
Gavin, J.B.3
Wilson, W.R.4
-
18
-
-
0025320055
-
Correlation between in vivo induction of cytokine gene expression by flavone acetic acid and strict close-denpency and therapeutic efficacy against murine renal cancer
-
Mace KF, Hornung RL, Wiltrout RH, Young HA. Correlation between in vivo induction of cytokine gene expression by flavone acetic acid and strict close-denpency and therapeutic efficacy against murine renal cancer. Cancer Res. 50(6), 1742-1747 (1990).
-
(1990)
Cancer Res
, vol.50
, Issue.6
, pp. 1742-1747
-
-
Mace, K.F.1
Hornung, R.L.2
Wiltrout, R.H.3
Young, H.A.4
-
19
-
-
0024330132
-
Flavone acetic acid-preclinical and clinical activity
-
Kerr DJ, Kaye SB. Flavone acetic acid-preclinical and clinical activity. Eur. J. Cancer Clin. Oncol. 25, 1271-1272 (1989).
-
(1989)
Eur. J. Cancer Clin. Oncol
, vol.25
, pp. 1271-1272
-
-
Kerr, D.J.1
Kaye, S.B.2
-
20
-
-
0028124643
-
Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents
-
Zwi LJ, Baguley BC, Gavin JB, Wilson WR. Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents. Oncol. Res. 6, 79-85 (1994).
-
(1994)
Oncol. Res
, vol.6
, pp. 79-85
-
-
Zwi, L.J.1
Baguley, B.C.2
Gavin, J.B.3
Wilson, W.R.4
-
21
-
-
0025317052
-
Potential antitumor agents. 60. Relationships between structure and in vivo colon 38 activity for 5-substituted 9-oxoxanthene-4-acetic acids
-
Atwell GJ, Rewcastle GW, Baguley BC, Denny WA. Potential antitumor agents. 60. Relationships between structure and in vivo colon 38 activity for 5-substituted 9-oxoxanthene-4-acetic acids. J. Med. Chem. 33, 1375-1379 (1990).
-
(1990)
J. Med. Chem
, vol.33
, pp. 1375-1379
-
-
Atwell, G.J.1
Rewcastle, G.W.2
Baguley, B.C.3
Denny, W.A.4
-
22
-
-
0031858141
-
Enhancement of the antitumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs
-
Lash CJ, Li AE, Rutland M, Baguley BC, Zwi LJ, Wilson WR. Enhancement of the antitumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs. Br. J. Cancer 78, 439-445 (1998).
-
(1998)
Br. J. Cancer
, vol.78
, pp. 439-445
-
-
Lash, C.J.1
Li, A.E.2
Rutland, M.3
Baguley, B.C.4
Zwi, L.J.5
Wilson, W.R.6
-
23
-
-
0033567097
-
Enhancement of antibody-directed enzyme prodrug therapy in colorectal xenografts by an antivascular agent
-
Pedley RB, Sharma SK, Boxer GM et al. Enhancement of antibody-directed enzyme prodrug therapy in colorectal xenografts by an antivascular agent. Cancer Res. 59(16), 3998-4003 (1999).
-
(1999)
Cancer Res
, vol.59
, Issue.16
, pp. 3998-4003
-
-
Pedley, R.B.1
Sharma, S.K.2
Boxer, G.M.3
-
24
-
-
0034662648
-
Scintigraphic imaging of the hypoxia marker (99m)Techtnetium-labeled 2,2′-1,4-diaminobutane)bis(2-methyl-3-butanone) dioxime (Tc-99m-labeled HL-91; Prognox): Noninvasive detection of tumor response to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid
-
Siim BG, Laux WT, Rutland MD, Palmer BN, Wilson WR. Scintigraphic imaging of the hypoxia marker (99m)Techtnetium-labeled 2,2′-1,4-diaminobutane)bis(2-methyl-3-butanone) dioxime (Tc-99m-labeled HL-91; Prognox): noninvasive detection of tumor response to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid. Cancer Res. 60(16), 4582-4588 (2000).
-
(2000)
Cancer Res
, vol.60
, Issue.16
, pp. 4582-4588
-
-
Siim, B.G.1
Laux, W.T.2
Rutland, M.D.3
Palmer, B.N.4
Wilson, W.R.5
-
25
-
-
0029063213
-
Induction of tumour necrosis factor-α by single and repeated doses of the antitumor agent 5,6-dimethylxanthenone4-acetic acid
-
Philpott M, Baguley BC, Ching L-M. Induction of tumour necrosis factor-α by single and repeated doses of the antitumor agent 5,6-dimethylxanthenone4-acetic acid. Cancer Chemother. Pharmacol. 36, 143-148 (1995).
-
(1995)
Cancer Chemother. Pharmacol
, vol.36
, pp. 143-148
-
-
Philpott, M.1
Baguley, B.C.2
Ching, L.-M.3
-
26
-
-
0029087486
-
Effect of thalidomide on tumour necrosis factor production and antitumour activity induced by 5,6-dimethylxanthenone-4-acetic acid
-
Ching L-M, Xu Z-F, Gummer BH, Palmer BD, Joseph WR, Baguley BC. Effect of thalidomide on tumour necrosis factor production and antitumour activity induced by 5,6-dimethylxanthenone-4-acetic acid. Br. J. Cancer 72, 339-343 (1995).
-
(1995)
Br. J. Cancer
, vol.72
, pp. 339-343
-
-
Ching, L.-M.1
Xu, Z.-F.2
Gummer, B.H.3
Palmer, B.D.4
Joseph, W.R.5
Baguley, B.C.6
-
27
-
-
0032895102
-
Thalidomide increases both intra-tumoural tumour necrosis factors production and antitumour activity in response to 5,6-dimethylxanthenone-4-acetic acid
-
Cao Z, Joseph WR, Browne WL et al. Thalidomide increases both intra-tumoural tumour necrosis factors production and antitumour activity in response to 5,6-dimethylxanthenone-4-acetic acid. Br. J. Cancer 80(5-6), 716-723 (1999).
-
(1999)
Br. J. Cancer
, vol.80
, Issue.5-6
, pp. 716-723
-
-
Cao, Z.1
Joseph, W.R.2
Browne, W.L.3
-
28
-
-
0033565644
-
Induction of intratumoral tumor necrosis factor (INF) synthesis and hemorrhagic necrosis by 5,6-dimethylxantenone-4-acetic acid (DMXAA) in TNF knockout mice
-
Ching LM, Goldsmith D, Joseph WR, Korner H, Sedgwick JD, Baguley BC. Induction of intratumoral tumor necrosis factor (INF) synthesis and hemorrhagic necrosis by 5,6-dimethylxantenone-4-acetic acid (DMXAA) in TNF knockout mice. Cancer Res. 59(14), 3304-3307 (1999).
-
(1999)
Cancer Res
, vol.59
, Issue.14
, pp. 3304-3307
-
-
Ching, L.M.1
Goldsmith, D.2
Joseph, W.R.3
Korner, H.4
Sedgwick, J.D.5
Baguley, B.C.6
-
29
-
-
0037068317
-
The antitumour activity of 5,6-dimethylxanthenone-4-acedc acid (DMXAA) in TNF receptors-1 knockout mice
-
(In Press)
-
Zhao L, Baguley BC, Kestell P, Ching L-M. The antitumour activity of 5,6-dimethylxanthenone-4-acedc acid (DMXAA) in TNF receptors-1 knockout mice. Br. J. Cancer (2002) (In Press).
-
(2002)
Br. J. Cancer
-
-
Zhao, L.1
Baguley, B.C.2
Kestell, P.3
Ching, L.-M.4
-
30
-
-
0028280239
-
Induction of tumor necrosis factors messenger RNA in human and murine cells by the flavone acetic acid analogue 5,6-dimedithylxanthenone-4-acetic acid (NSC 640488)
-
Ching LM, Joseph WF, Crosier KE, Baguley BC. Induction of tumor necrosis factors messenger RNA in human and murine cells by the flavone acetic acid analogue 5,6-dimedithylxanthenone-4-acetic acid (NSC 640488). Cancer Res. 54, 870 872 (1994).
-
(1994)
Cancer Res
, vol.54
, pp. 870-872
-
-
Ching, L.M.1
Joseph, W.F.2
Crosier, K.E.3
Baguley, B.C.4
-
31
-
-
0025793698
-
Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine - Evidence for a vascular mechanism
-
Baguley BC, Holdaway KM, Thomsen LL, Zhuang L, Zwi LJ. Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine - evidence for a vascular mechanism. Eur. J. Cancer 27(4), 482-487 (1991).
-
(1991)
Eur. J. Cancer
, vol.27
, Issue.4
, pp. 482-487
-
-
Baguley, B.C.1
Holdaway, K.M.2
Thomsen, L.L.3
Zhuang, L.4
Zwi, L.J.5
-
32
-
-
0001851181
-
Colchicine in the experimental chemotherapy of cancer
-
Ludford RJ. Colchicine in the experimental chemotherapy of cancer. J. Natl Cancer Inst. 6, 411-441 (1945).
-
(1945)
J. Natl. Cancer Inst
, vol.6
, pp. 411-441
-
-
Ludford, R.J.1
-
33
-
-
0027173672
-
Vinca alkaloids - Antivascular effects in a murine tumour
-
Hill SA, Lonergan SJ, Denekamp J, Chaplin DJ. Vinca alkaloids - antivascular effects in a murine tumour. Eur. J. Cancer 29A, 1320-1324 (1993).
-
(1993)
Eur. J. Cancer
, vol.29 A
, pp. 1320-1324
-
-
Hill, S.A.1
Lonergan, S.J.2
Denekamp, J.3
Chaplin, D.J.4
-
34
-
-
0028210648
-
The effect of Vinca alkaloids on tumour blood flow
-
Hill SA, Lonergan SJ, Denekamp J, Chaplin DJ. The effect of Vinca alkaloids on tumour blood flow. Adv. Exp. Med. Biol. 345, 417-422 (1994).
-
(1994)
Adv. Exp. Med. Biol
, vol.345
, pp. 417-422
-
-
Hill, S.A.1
Lonergan, S.J.2
Denekamp, J.3
Chaplin, D.J.4
-
35
-
-
0030625644
-
Increased Plasma serotonin following treatment with flavone-8-acetic acid, 5,6-dimethlylxanthenone-4-acetic acid, vinblastine and colchicine - Relation to vascular effects
-
Baguley BC, Zhuang L, Kestell P. Increased Plasma serotonin following treatment with flavone-8-acetic acid, 5,6-dimethlylxanthenone-4-acetic acid, vinblastine and colchicine - relation to vascular effects. Oncol. Res. 9(2), 55-60 (1997).
-
(1997)
Oncol. Res
, vol.9
, Issue.2
, pp. 55-60
-
-
Baguley, B.C.1
Zhuang, L.2
Kestell, P.3
-
36
-
-
0018387446
-
Promotion of microtubule assembly in vitro by Taxol
-
Schiff PB, Fant J, Horwitz SB. Promotion of microtubule assembly in vitro by Taxol. Nature 277, 665-667 (1979).
-
(1979)
Nature
, vol.277
, pp. 665-667
-
-
Schiff, P.B.1
Fant, J.2
Horwitz, S.B.3
-
37
-
-
0030951899
-
Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
-
Dark GG, Hill SA, Prise VE, Tozer GM, Pettit GR, Chaplin DJ. Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res. 57(10), 1829-1834 (1997).
-
(1997)
Cancer Res
, vol.57
, Issue.10
, pp. 1829-1834
-
-
Dark, G.G.1
Hill, S.A.2
Prise, V.E.3
Tozer, G.M.4
Pettit, G.R.5
Chaplin, D.J.6
-
38
-
-
0000266648
-
Phase I pharmacokinetic and toxicity study of weekly iv. combretastatin A4 phosphate (CA4P)
-
Stratford M, Folkes L, Galbraith S et al. Phase I pharmacokinetic and toxicity study of weekly iv. combretastatin A4 phosphate (CA4P). Clin. Cancer Res. 6, S280 (2000).
-
(2000)
Clin. Cancer Res
, vol.6
-
-
Stratford, M.1
Folkes, L.2
Galbraith, S.3
-
39
-
-
0037125028
-
Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethyl xanthenone-4-acetic acid
-
Ching L-M, Cao Z, Kieda C, Swain S, Jameson MB, Baguley BC. Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid. Br. Cancer 86, 1937-1942 (2002).
-
(2002)
Br. Cancer
, vol.86
, pp. 1937-1942
-
-
Ching, L.-M.1
Cao, Z.2
Kieda, C.3
Swain, S.4
Jameson, M.B.5
Baguley, B.C.6
-
40
-
-
0035164766
-
Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents
-
Kestell P, Zhao L, Jameson M, Stratford MRL, Folkes LY, Baguley BC. Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents. Clin. Chim. Acta 314, 159-166 (2001).
-
(2001)
Clin. Chim. Acta
, vol.314
, pp. 159-166
-
-
Kestell, P.1
Zhao, L.2
Jameson, M.3
Stratford, M.R.L.4
Folkes, L.Y.5
Baguley, B.C.6
-
41
-
-
0026587009
-
Endotoxin, interieukin-1 and tumor necrosis factor cause neutrophil dependent microvascular leakage in postcapillary venules
-
Yi ES, Ulich TR. Endotoxin, interieukin-1 and tumor necrosis factor cause neutrophil dependent microvascular leakage in postcapillary venules. Am. J. Pathol. 140(3), 659-663 (1992).
-
(1992)
Am. J. Pathol
, vol.140
, Issue.3
, pp. 659-663
-
-
Yi, E.S.1
Ulich, T.R.2
-
42
-
-
0026089375
-
Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice
-
Thomsen LL, Ching LM Zhuang I, Gavin JB, Baguley BC. Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice. Cancer Res. 510), 77-81 (1991).
-
(1991)
Cancer Res
, vol.51
, Issue.1
, pp. 77-81
-
-
Thomsen, L.L.1
Ching, L.M.2
Zhuang, I.3
Gavin, J.B.4
Baguley, B.C.5
-
43
-
-
0034812637
-
The antitumour agent 5,6-dimethylxan thenone4-aceric acid acts in vitro on human mononuclear cells as a co-stimulator to other inducers of tumour necrosis factor
-
Philpott M, Ching LM, Baguley BC. The antitumour agent 5,6-dimethylxanthenone4-aceric acid acts in vitro on human mononuclear cells as a co-stimulator to other inducers of tumour necrosis factor. Eur. J. Cancer 37, 1930-1937 (2001).
-
(2001)
Eur. J. Cancer
, vol.37
, pp. 1930-1937
-
-
Philpott, M.1
Ching, L.M.2
Baguley, B.C.3
-
44
-
-
0026686247
-
Antitumour responses to flavone-8-acetic acid and 5,6-dimethylx andienone-4-acetic acid in immune deficient mice
-
Ching LM, Joseph WP, Baguley BC. Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxandienone-4-acetic acid in immune deficient mice. Br. J Cancer 66(1), 128-130 (1992).
-
(1992)
Br. J. Cancer
, vol.66
, Issue.1
, pp. 128-130
-
-
Ching, L.M.1
Joseph, W.P.2
Baguley, B.C.3
-
45
-
-
0032487857
-
The anti-inflammitory agents aspirin and salicylate inhibit the activity of IκB kinase-P
-
6706
-
Yin MJ, Yamamoto Y, Gaynor RB. The anti-inflammitory agents aspirin and salicylate inhibit the activity of IκB kinase-P. Nature 396(6706), 77-80 (1998).
-
(1998)
Nature
, vol.396
, pp. 77-80
-
-
Yin, M.J.1
Yamamoto, Y.2
Gaynor, R.B.3
-
46
-
-
0030002174
-
Ablation of colorectal xenografts with combined radioinimunotherapy and tumor blood flow-modifying agents
-
Pedley RB, Boden JA. Boden R et al. Ablation of colorectal xenografts with combined radioinimunotherapy and tumor blood flow-modifying agents. Cancer Res. 56(14), 3293-3300 (1996).
-
(1996)
Cancer Res
, vol.56
, Issue.14
, pp. 3293-3300
-
-
Pedley, R.B.1
Boden, J.A.2
Boden, R.3
-
47
-
-
0029902597
-
Antivascular approaches to solid tumour therapy - Evaluation of tubulin binding agents
-
Chaplin DJ, Pettit GR. Parkins CS, Hill SA. Antivascular approaches to solid tumour therapy - evaluation of tubulin binding agents. Br. J. Cancer 74, S86-S88 (1996).
-
(1996)
Br. J. Cancer
, vol.74
-
-
Chaplin, D.J.1
Pettit, G.R.2
Parkins, C.S.3
Hill, S.A.4
-
48
-
-
0032053823
-
The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
-
Brown JM, Giaccia AJ. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res. 58(7), 1408-1416 (1998).
-
(1998)
Cancer Res
, vol.58
, Issue.7
, pp. 1408-1416
-
-
Brown, J.M.1
Giaccia, A.J.2
-
49
-
-
0010992283
-
Tumor physiology and drug resistance
-
Tannock IF. Tumor physiology and drug resistance. Lancet 351, 9-16 (1998).
-
(1998)
Lancet
, vol.351
, pp. 9-16
-
-
Tannock, I.F.1
-
50
-
-
0031016945
-
Mechanisms of enhancement of the antitumour activity of melphalan by the tumour blood flow inhibitor 5,6-dimethylxanthenone-4-acetic acid
-
Pruijn FB, van Daalen M, Holford NHG, Wilson WR. Mechanisms of enhancement of the antitumour activity of melphalan by the tumour blood flow inhibitor 5,6-dimethylxanthenone-4-acetic acid. Cancer Chemother Pharmacol. 39, 541-546 (1997).
-
(1997)
Cancer Chemother. Pharmacol
, vol.39
, pp. 541-546
-
-
Pruijn, F.B.1
van Daalen, M.2
Holford, N.H.G.3
Wilson, W.R.4
-
51
-
-
0034923996
-
Improving local tumor control by combining vascular targeting drugs, mild hyperthermia and radiation
-
Horsman MR, Murata R, Overgaard J. Improving local tumor control by combining vascular targeting drugs, mild hyperthermia and radiation. Acta Oncol. 40(4), 497-503 (2001).
-
(2001)
Acta Oncol
, vol.40
, Issue.4
, pp. 497-503
-
-
Horsman, M.R.1
Murata, R.2
Overgaard, J.3
-
52
-
-
0026970404
-
Nuclear factor kappa B - An oxidative stress-responsive transcription factor of eukaryotic cells (a review)
-
Schreck R, Albermann K, Baeuerle PA. Nuclear factor kappa B - an oxidative stress-responsive transcription factor of eukaryotic cells (a review). Free. Radic. Res. Commun. 17, 221-237 (1992).
-
(1992)
Free. Radic. Res. Commun
, vol.17
, pp. 221-237
-
-
Schreck, R.1
Albermann, K.2
Baeuerle, P.A.3
-
53
-
-
0031775298
-
Enhancement of tumor radiation response by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
-
Wilson WR, Li AE, Cowan DSM, Siim BG. Enhancement of tumor radiation response by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Int. J. Radiat. Oncol. Biol. Phys. 42(4), 905-908 (1998).
-
(1998)
Int. J. Radiat. Oncol. Biol. Phys
, vol.42
, Issue.4
, pp. 905-908
-
-
Wilson, W.R.1
Li, A.E.2
Cowan, D.S.M.3
Siim, B.G.4
-
54
-
-
0034759198
-
Improved tumor response by combining radiation and the vascular-damaging drug 5,6-dimethy lxanthenone-4-acetic acid
-
Murata R, Siemann DW, Overgaard J, Horsman MR. Improved tumor response by combining radiation and the vascular-damaging drug 5,6-dimethylxanthenone-4-acetic acid. Radiat. Res. 156, 503-509 (2001).
-
(2001)
Radiat. Res
, vol.156
, pp. 503-509
-
-
Murata, R.1
Siemann, D.W.2
Overgaard, J.3
Horsman, M.R.4
-
55
-
-
0028234390
-
Combining bioreductive drugs (SR 4233 or SN 23862) with the vasoactive agents flavone acetic acid or 5,6-dimethy lxanthenone acetic acid
-
Cliffe S, Taylor ML, Rutland M, Baguley BC, Hill RP, Wilson WR. Combining bioreductive drugs (SR 4233 or SN 23862) with the vasoactive agents flavone acetic acid or 5,6-dimethylxanthenone acetic acid. Int. J. Radiat. Oncol. Biol. Phys. 29, 373 377 (1994).
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys
, vol.29
, pp. 373-377
-
-
Cliffe, S.1
Taylor, M.L.2
Rutland, M.3
Baguley, B.C.4
Hill, R.P.5
Wilson, W.R.6
-
56
-
-
0028864273
-
Hypoxia-activated prodrugs as antitumour agents: Strategies for maximising tumour cell killing
-
Wilson WR, Pruijn FB. Hypoxia-activated prodrugs as antitumour agents: strategies for maximising tumour cell killing. Clin. Exp. Pharmacol. Physiol. 22, 881-885 (1995).
-
(1995)
Clin. Exp. Pharmacol. Physiol
, vol.22
, pp. 881-885
-
-
Wilson, W.R.1
Pruijn, F.B.2
-
57
-
-
0029935930
-
Tertiary amine N-oxides as bioreductive drugs: DACA N-oxide, nitracrine N-oxide and AQ4N
-
Wilson WR, Denny WA, Pullen SM et al. Tertiary amine N-oxides as bioreductive drugs: DACA N-oxide, nitracrine N-oxide and AQ4N. Br. J. Cancer 74, S43-S47 (1996).
-
(1996)
Br. J. Cancer
, vol.74
-
-
Wilson, W.R.1
Denny, W.A.2
Pullen, S.M.3
-
58
-
-
0031017640
-
Chemotherapy with DMXAA (5,6-dimethylxanthenone-4-acetic acid) in combination with CI-1010 (1H-in,imidazole-1-ethanol,alpha-[ [(2-bromoethyl)amino]methyl]-2-nitro-,monohydrobromide (R isomer)) against advanced stage murine colon carcinoma 26
-
Vincent PW, Roberts BJ, Elliott WL, Leopold WR. Chemotherapy with DMXAA (5,6-dimethylxanthenone-4-acetic acid) in combination with CI-1010 (1H-in,imidazole-1-ethanol,alpha-[[(2-bromoethyl)amino]methyl] -2-nitro-, monohydrobromide (R isomer)) against advanced stage murine colon carcinoma 26. Oncol. Rep. 4(1), 143-147 (1997).
-
(1997)
Oncol. Rep
, vol.4
, Issue.1
, pp. 143-147
-
-
Vincent, P.W.1
Roberts, B.J.2
Elliott, W.L.3
Leopold, W.R.4
-
59
-
-
0026520313
-
Bisbioreductive agents as hypoxia-selective cytotoxins - Nitracrine N-oxide
-
Wilson WR, Vanzijl P, Denny WA. Bisbioreductive agents as hypoxia-selective cytotoxins - nitracrine N-oxide. Int. J. Radiat. Oncol. Biol. Phys. 22, 693-696 (1992).
-
(1992)
Int. J. Radiat. Oncol. Biol. Phys
, vol.22
, pp. 693-696
-
-
Wilson, W.R.1
Vanzijl, P.2
Denny, W.A.3
-
60
-
-
0026775234
-
5-nitro-4-(N,N-dimethy laminopropylamino)quinoline (5-nitraquine), a new DNA-affinic hypoxic cell radiosensitizer and bioreductive agent comparison with nitracrine
-
Wilson WR, Siim BG, Denny WA et al. 5-nitro-4-(N,N-dimethylaminopropylamino)quinoline (5-nitraquine), a new DNA-affinic hypoxic cell radiosensitizer and bioreductive agent comparison with nitracrine. Radiat. Res. 131(3), 257-265 (1992).
-
(1992)
Radiat. Res
, vol.131
, Issue.3
, pp. 257-265
-
-
Wilson, W.R.1
Siim, B.G.2
Denny, W.A.3
-
61
-
-
0028263652
-
Does DNA targeting affect the cytotoxicity and cell uptake of basic nitroquinoline bioreductive drugs?
-
Siim BG, Denny WA, Wilson WR. Does DNA targeting affect the cytotoxicity and cell uptake of basic nitroquinoline bioreductive drugs? Int. J. Radiat. Oncol. Biol. Phys. 29, 311-315 (1994).
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys
, vol.29
, pp. 311-315
-
-
Siim, B.G.1
Denny, W.A.2
Wilson, W.R.3
-
62
-
-
0036093852
-
Novel strategies for overcoming multi-drug resistance in cancer
-
Baguley BC. Novel strategies for overcoming multi-drug resistance in cancer. BioDrugs 16, 97-103 (2002).
-
(2002)
BioDrugs
, vol.16
, pp. 97-103
-
-
Baguley, B.C.1
-
63
-
-
0029858387
-
TNF and cancer therapy-induced apoptosis - Potentiation by inhibition of NFκB
-
5288
-
Wang CY, Mayo MW, Baldwin AS. TNF and cancer therapy-induced apoptosis - potentiation by inhibition of NFκB. Science 274(5288), 784-787 (1996).
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin, A.S.3
-
64
-
-
0001296910
-
Combination of the antivascular agent DMXAA with radiation and chemotherapy
-
Wilson WR, Baguley BC. Combination of the antivascular agent DMXAA with radiation and chemotherapy. Int. J. Radiat. Oncol. Biol. Phys. 46, 706 (2000).
-
(2000)
Int. J. Radiat. Oncol. Biol. Phys
, vol.46
, pp. 706
-
-
Wilson, W.R.1
Baguley, B.C.2
-
65
-
-
0036568457
-
Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy
-
Siemann DW, Mercer E, Lepler S, Rojiani AM. Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy. Int. J. Cancer 99 (1), 1-6 (2002).
-
(2002)
Int. J. Cancer
, vol.99
, Issue.1
, pp. 1-6
-
-
Siemann, D.W.1
Mercer, E.2
Lepler, S.3
Rojiani, A.M.4
-
66
-
-
0028263706
-
Enhancement of radioimmunotherapy by drugs modifying tumour blood flow in a colonic xenograft model
-
Pedley RB, Begent RH, Boden JA, Boxer GM, Boden R, Keep PA. Enhancement of radioimmunotherapy by drugs modifying tumour blood flow in a colonic xenograft model. Int. J. Cancer 57(6), 830-835 (1994).
-
(1994)
Int. J. Cancer
, vol.57
, Issue.6
, pp. 830-835
-
-
Pedley, R.B.1
Begent, R.H.2
Boden, J.A.3
Boxer, G.M.4
Boden, R.5
Keep, P.A.6
-
67
-
-
0035158004
-
Potentiation of the antitumour effect of hyperthermia by combining with the vascular targeting agent 5,6-dimethylxa nthenone-4-acetic acid
-
Murata F. Overgaard J, Horsman MR. Potentiation of the antitumour effect of hyperthermia by combining with the vascular targeting agent 5,6-dimethylxanthenone-4-acetic acid. Int. J. Hyperthermia 17(6), 508-519 (2001).
-
(2001)
Int. J. Hyperthermia
, vol.17
, Issue.6
, pp. 508-519
-
-
Murata, F.1
Overgaard, J.2
Horsman, M.R.3
-
68
-
-
0036284788
-
HSP70 protects against TNF-induced lethal inflammatory shock
-
Van MW, Welockx B, Mahieu T et al. HSP70 protects against TNF-induced lethal inflammatory shock. Immunity 16(5), 685-695 (2002).
-
(2002)
Immunity
, vol.16
, Issue.5
, pp. 685-695
-
-
Van, M.W.1
Welockx, B.2
Mahieu, T.3
-
69
-
-
0035866391
-
Interferon-inducible protein 10 induction and inhibition of angiogenesis in vivo by the antitumor agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
-
Cao Z, Baguley BC, Ching L-M. Interferon-inducible protein 10 induction and inhibition of angiogenesis in vivo by the antitumor agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Cancer Res. 61, 1517-1521 (2001).
-
(2001)
Cancer Res
, vol.61
, pp. 1517-1521
-
-
Cao, Z.1
Baguley, B.C.2
Ching, L.-M.3
-
70
-
-
0028216334
-
Thalidomide is an inhibitor of angiogenesis
-
D'Amato RJ, Loughnan MS, Flynn E, Folkman J. Thalidomide is an inhibitor of angiogenesis. Proc. Natl Acad. Sci. USA 91, 4082-4085(1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4082-4085
-
-
D'Amato, R.J.1
Loughnan, M.S.2
Flynn, E.3
Folkman, J.4
-
71
-
-
0031760365
-
Thalidomide revisited: Pharmacology and clinical applications
-
Calabrese L, Resztak K. Thalidomide revisited: pharmacology and clinical applications. Exp. Opin. Investig. Drugs 7 (1998).
-
(1998)
Exp. Opin. Investig. Drugs
, pp. 7
-
-
Calabrese, L.1
Resztak, K.2
-
72
-
-
0003211696
-
Anti-angiogenic treatment of metatstatic melanoma, renal cell, ovarian and breast cancers with thalidomide: A Phase II study
-
Eisen T, Boshoff C, Vaughan MM. Anti-angiogenic treatment of metatstatic melanoma, renal cell, ovarian and breast cancers with thalidomide: a Phase II study. Proc. Am. Soc. Clin. Oncol. 17, 441a (1998).
-
(1998)
Proc. Am. Soc. Clin. Oncol
, vol.17
-
-
Eisen, T.1
Boshoff, C.2
Vaughan, M.M.3
-
73
-
-
0026080801
-
Thalidomide selectively inhibits tumor necrosis factor-α production by stimulated human monocytes
-
Sampaio EP, Sarno EN, Galilly R, Cohn ZA, Kaplan G. Thalidomide selectively inhibits tumor necrosis factor-α production by stimulated human monocytes. J. Exp. Med 173(3), 699-703 (1991).
-
(1991)
J. Exp. Med
, vol.173
, Issue.3
, pp. 699-703
-
-
Sampaio, E.P.1
Sarno, E.N.2
Galilly, R.3
Cohn, Z.A.4
Kaplan, G.5
-
74
-
-
0031846669
-
Interaction of thalidomide, phthalimide analogues of thalidomide and pentoxifylline with the antitumour agent 5,6-dimethylxanthenone-4-acetic acid: Concomitant reduction of serum tumour necrosis factor-α and enhancement of antitumour activity
-
Ching LM, Browne WL, Tchernegovski R, Gregory T, Baguley BC, Palmer BD. Interaction of thalidomide, phthalimide analogues of thalidomide and pentoxifylline with the antitumour agent 5,6-dimethylxanthenone-4-acetic acid: concomitant reduction of serum tumour necrosis factor-α and enhancement of antitumour activity, Br J. Cancer 78, 336-343 (1998).
-
(1998)
Br. J. Cancer
, vol.78
, pp. 336-343
-
-
Ching, L.M.1
Browne, W.L.2
Tchernegovski, R.3
Gregory, T.4
Baguley, B.C.5
Palmer, B.D.6
-
75
-
-
0035933772
-
Inhibition of NF-κB activity by thalidomide through suppression of I-κB kinase activity
-
Keifer JA, Guttridge DC, Ashburner BP, Baldwin AS Jr. Inhibition of NF-κB activity by thalidomide through suppression of I-κB kinase activity. J. Biol. Chem 276, 22382-22387 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 22382-22387
-
-
Keifer, J.A.1
Guttridge, D.C.2
Ashburner, B.P.3
Baldwin A.S., Jr.4
-
76
-
-
0029922290
-
Thalidomide can be either agonistic or antagonistic to LPS evoked synthesis of TNF-α by mononuclear cells
-
Shannon EJ, Sandoval F. Thalidomide can be either agonistic or antagonistic to LPS evoked synthesis of TNF-α by mononuclear cells. Immunopharmacol. Immunotoxicol. 18(1), 59-72 (1996).
-
(1996)
Immunopharmacol. Immunotoxicol
, vol.18
, Issue.1
, pp. 59-72
-
-
Shannon, E.J.1
Sandoval, F.2
-
77
-
-
0033895294
-
Modulation of the pharmacokinetics of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice by thalidomide
-
Kestell P, Zhao, L, Baguley BC et al. Modulation of the pharmacokinetics of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice by thalidomide. Cancer Chemother. Pharmacol. 46, 135-141 (2000).
-
(2000)
Cancer Chemother. Pharmacol
, vol.46
, pp. 135-141
-
-
Kestell, P.1
Zhao, L.2
Baguley, B.C.3
-
78
-
-
0035064594
-
Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo
-
Galbraith SM, Chaplin DJ, Lee F et al. Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo. Anticancer Res. 21 (1A), 93-102 (2001).
-
(2001)
Anticancer Res
, vol.21
, Issue.1 A
, pp. 93-102
-
-
Galbraith, S.M.1
Chaplin, D.J.2
Lee, F.3
-
79
-
-
0011004229
-
Effect of 5-hydroxytryptamine and cyproheptadine on tumour blood flow. Estimation by rate of cooling after microwave diathermy
-
Cater DB, Petrie X Watkinson DA. Effect of 5-hydroxytryptamine and cyproheptadine on tumour blood flow. Estimation by rate of cooling after microwave diathermy. Acta Radiolog. Ther. Phys. Biol. 3, 109-128 (1965).
-
(1965)
Acta Radiolog. Ther. Phys. Biol
, vol.3
, pp. 109-128
-
-
Cater, D.B.1
Petrie, X.2
Watkinson, D.A.3
-
80
-
-
0027375380
-
Serotonin involvement in the antitumour and host effects of flavone-8 acetic acid and 5,6-dimethylxanthenone-4 acetic acid
-
Baguley BC, Cole G, Thomsen LL, Zhuang L. Serotonin involvement in the antitumour and host effects of flavone-8 acetic acid and 5,6-dimethylxanthenone-4 acetic acid. Cancer Chemother Pharmacol. 33, 77-81 (1993).
-
(1993)
Cancer Chemother. Pharmacol
, vol.33
, pp. 77-81
-
-
Baguley, B.C.1
Cole, G.2
Thomsen, L.L.3
Zhuang, L.4
-
81
-
-
0035001007
-
Effects of the serotonin receptor antagonist cyproheptadine on the activity and pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
-
Zhao L, Kestell P, Philpott M, Ching L-M, Zhuang L, Baguley BC. Effects of the serotonin receptor antagonist cyproheptadine on the activity and pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Cancer Chemother. Pharmacol. 47, 491-497 (2001).
-
(2001)
Cancer Chemother. Pharmacol
, vol.47
, pp. 491-497
-
-
Zhao, L.1
Kestell, P.2
Philpott, M.3
Ching, L.-M.4
Zhuang, L.5
Baguley, B.C.6
-
82
-
-
0026624915
-
Reversal of multi-drug resistance by phenothiazines and structurally related compounds
-
Ramu A, Ramu N. Reversal of multi-drug resistance by phenothiazines and structurally related compounds. Cancer Chemother. Pharmacol. 30(3), 165-173 (1992).
-
(1992)
Cancer Chemother. Pharmacol
, vol.30
, Issue.3
, pp. 165-173
-
-
Ramu, A.1
Ramu, N.2
-
83
-
-
0035266136
-
Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci
-
Kanwar JR, Kanwar RK, Pandey S, Ching LM, Krissansen GW. Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci. Cancer Res. 61(5), 1948-1956 (2001).
-
(2001)
Cancer Res
, vol.61
, Issue.5
, pp. 1948-1956
-
-
Kanwar, J.R.1
Kanwar, R.K.2
Pandey, S.3
Ching, L.M.4
Krissansen, G.W.5
-
84
-
-
0037222218
-
Marked potentiation of the aintitumor activity of chemotherapeutic drugs by antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
-
(In Press)
-
Simm BG, Lee AE, Shalal-Zwain S, Pruijn FB, McKeage W, Wilson WR. Marked potentiation of the aintitumor activity of chemotherapeutic drugs by antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Cancer Chemother. Pharmacol. (2002) (In Press).
-
(2002)
Cancer Chemother. Pharmacol
-
-
Simm, B.G.1
Lee, A.E.2
Shalal-Zwain, S.3
Pruijn, F.B.4
McKeage, W.5
Wilson, W.R.6
|