A protein disulfide isomerase expressed in the embryonic midline is required for left/right asymmetries

Genes and Development

Volumn 16, Issue 19, 2002, Pages 2518-2529

  Hoshijima, Kazuyuki ^a   Metherall, James E ^a   Grunwald, David Jonah ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Heart morphogenesis; Laterality patterning; Midline; PDI

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DISULFIDE ISOMERASE P5; MORPHOLINE DERIVATIVE; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; GASTRULA; GENE EXPRESSION; GENE FUNCTION; GENETIC CODE; GENETIC SCREENING; HEART DEVELOPMENT; INTESTINE; LIVER DEVELOPMENT; MESODERM; MUTANT; NONHUMAN; ORGANOGENESIS; PANCREAS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WILD TYPE; ZEBRA FISH;

ANIMALS; BASE SEQUENCE; BODY PATTERNING; DNA, COMPLEMENTARY; GASTRULA; GENE EXPRESSION; MOLECULAR SEQUENCE DATA; MORPHOGENESIS; PROTEIN DISULFIDE-ISOMERASE; ZEBRAFISH;

ANIMALIA; DANIO RERIO; VERTEBRATA;

EID: 0036790739     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1001302     Document Type: Article

References (60)

1. Bisgrove, B.W. and Yost, H.J. 2001. Classification of left-right patterning defects in zebrafish, mice, and humans. Am. J. Med. Genet. 101: 315-323.
2. Bisgrove, B.W., Essner, J.J., and Yost, H.J. 1999. Regulation of midline development by antagonism of lefty and nodal signaling. Development 126: 3253-3262.
3. Bisgrove, B.W., Essner, J.J., and Yost, H.J. 2000. Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry. Development 127: 3567-3579.
4. Brown, D.D., Wang, Z., Furlow, J.D., Kanamori, A., Schwartzman, R.A., Remo, B.F., and Pinder, A. 1996. The thyroid hormone-induced tail resorption program during Xenopus laevis metamorphosis. Proc. Natl. Acad. Sci. 93: 1924-1929.
5. Burdine, R.D. and Schier, A.F. 2000. Conserved and divergent mechanisms in left-right axis formation. Genes & Dev. 14: 763-776.
6. Capdevila, J., Vogan, K.J., Tabin, C.J., and Izpisua Belmonte, J.C. 2000. Mechanisms of left-right determination in vertebrates. Cell 101: 9-21.
7. Chen, J.N. and Fishman, M.C. 1996. Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development 122: 3809-3816.
8. Chen, J.N., van Eeden, F.J., Warren, K.S., Chin, A., Nusslein-Volhard, C., Haffter, P., and Fishman, M.C. 1997. Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development 124: 4373-4382.
9. Chiang, C., Litingtung, Y., Lee, E., Young, K.E., Corden, J.L., Westphal, H., and Beachy, P.A. 1996. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383: 407-413.
10. Chin, A.J., Tsang, M., and Weinberg, E.S. 2000. Heart and gut chiralities are controlled independently from initial heart position in the developing zebrafish. Dev. Biol. 227: 403-421.
11. Concha, M.L., Burdine, R.D., Russell, C., Schier, A.F., and Wilson, S.W. 2000. A nodal signaling pathway regulates the laterality of neuroanatomical asymmetries in the zebrafish forebrain. Neuron 28: 399-409.
12. Danos, M.C. and Yost, H.J. 1996. Role of notochord in specification of cardiac left-right orientation in zebrafish and Xenopus. Dev. Biol. 177: 96-103.
13. Dufort, D., Schwartz, L., Harpal, K., and Rossant, J. 1998. The transcription factor HNF3β is required in visceral endoderm for normal primitive streak morphogenesis. Development 125: 3015-3025.
14. Dulac, C. and Axel, R. 1995. A novel family of genes encoding putative pheromone receptors in mammals. Cell 83: 195-206.
15. Essner, J.J., Branford, W.W., Zhang, J., and Yost, H.J. 2000. Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms. Development 127: 1081-1093.
16. Ferrari, D.M. and Soling, H.D. 1999. The protein disulphideisomerase family: Unraveling a string of folds. Biochem. J. 339: 1-10.
17. Freedman, R.B., Hirst, T.R., and Tuite, M.F. 1994. Protein disulphide isomerase: Building bridges in protein folding. Trends Biochem. Sci. 19: 331-336.
18. Fujinaga, M. 1997. Development of sidedness of asymmetric body structures in vertebrates. Int. J. Dev. Biol. 41: 153-186.
19. Goldstein, A.M., Ticho, B.S., and Fishman, M.C. 1998. Patterning the heart's left-right axis: From zebrafish to man. Dev. Genet. 22: 278-287.
20. Hamada, H., Meno, C., Watanabe, D., and Saijoh, Y. 2002. Establishment of vertebrate left-right asymmetry. Nat. Rev. Genet. 3: 103-113.
21. Hedrick, S.M., Cohen, D.I., Nielsen, E.A., and Davis, M.M. 1984. Isolation of cDNA clones encoding T cell-specific membrane-associated proteins. Nature 308: 149-153.
22. Izraeli, S., Lowe, L.A., Bertness, V.L., Good, D.J., Dorward, D.W., Kirsch, I.R., and Kuehn, M.R. 1999. The SIL gene is required for mouse embryonic axial development and left-right specification. Nature 399: 691-694.
23. Kelleher, D.J., Kreibich, G., and Gilmore, R. 1992. Oligosaccharyltransferase activity is associated with a protein complex composed of ribophorins I and II and a 48 kd protein. Cell 69: 55-65.
24. King, T., Beddington, R.S., and Brown, N.A. 1998. The role of the brachyury gene in heart development and left-right specification in the mouse. Mech. Dev. 79: 29-37.
25. Konsolaki, M. and Schupbach, T. 1998. windbeutel, a gene required for dorsoventral patterning in Drosophila, encodes a protein that has homologies to vertebrate proteins of the endoplasmic reticulum. Genes & Dev. 12: 120-131.
26. Kosaki, K. and Casey, B. 1998. Genetics of human left-right axis malformations. Semin. Cell. Dev. Biol. 9: 89-99.
27. Levin, M., Roberts, D.J., Holmes, L.B., and Tabin, C. 1996. Laterality defects in conjoined twins. Nature 384: 321.
28. Liang, J.O., Etheridge, A., Hantsoo, L., Rubinstein, A.L., Nowak, S.T., Izpisua Belmonte, J.C., and Halpern, M.E. 2000. Asymmetric nodal signaling in the zebrafish diencephalon positions the pineal organ. Development 127: 5101-5112.
29. Lohr, J.L., Danos, M.C., and Yost, H.J. 1997. Left-right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development. Development 124: 1465-1472.
30. Melloy, P.G., Ewart, J.L., Cohen, M.F., Desmond, M.E., Kuehn, M.R., and Lo, C.W. 1998. No turning, a mouse mutation causing left-right and axial patterning defects. Dev. Biol. 193: 77-89.
31. Meno, C., Shimono, A., Saijoh, Y., Yashiro, K., Mochida, K., Ohishi, S., Noji, S., Kondoh, H., and Hamada, H. 1998. lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal. Cell 94: 287-297.
32. Meno, C., Gritsman, K., Ohishi, S., Ohfuji, Y., Heckscher, E., Mochida, K., Shimono, A., Kondoh, H., Talbot, W.S., Robertson, E.J., et al. 1999. Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation. Mol. Cell 4: 287-298.
33. Metzler, M., Gertz, A., Sarkar, M., Schachter, H., Schrader, J.W., and Marth, J.D. 1994. Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development. EMBO J. 13: 2056-2065.
34. Nascone, N. and Mercola, M. 1997. Organizer induction determines left-right asymmetry in Xenopus. Dev. Biol. 189: 68-78.
35. Nasevicius, A. and Ekker, S.C. 2000. Effective targeted gene 'knockdown' in zebrafish. Nat. Genet. 26: 216-220.
36. Noiva, R. 1999. Protein disulfide isomerase: The multifunctional redox chaperone of the endoplasmic reticulum. Semin. Cell Dev. Biol. 10: 481-493.
37. Perou, C.M., Sorlie, T., Eisen, M.B., van de Rijn, M., Jeffrey, S.S., Rees, C.A., Pollack, J.R., Ross, D.T., Johnsen, H., Akslen, L.A., et al. 2000. Molecular portraits of human breast tumours. Nature 406: 747-752.
38. Rampoldi, L., Dobson-Stone, C., Rubio, J.P., Danek, A., Chalmers, R.M., Wood, N.W., Verellen, C., Ferrer, X., Malandrini, A., Fabrizi, G.M., et al. 2001. A conserved sorting-associated protein is mutant in chorea-acanthocytosis. Nat. Genet. 28: 119-120.
39. Rebagliati, M.R., Toyama, R., Fricke, C., Haffter, P., and Dawid, I.B. 1998. Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry. Dev. Biol. 199: 261-272.
40. Roessler, E. and Muenke, M. 2001. Midline and laterality defects: Left and right meet in the middle. Bioessays 23: 888-900.
41. Rubinstein, A.L., Lee, D., Luo, R., Henion, P.D., and Halpern, M.E. 2000. Genes dependent on zebrafish cyclops function identified by AFLP differential gene expression screen. Genesis 26: 86-97.
42. Sampath, K., Rubinstein, A.L., Cheng, A.M., Liang, J.O., Fekany, K., Solnica-Krezel, L., Korzh, V., Halpern, M.E., and Wright, C.V. 1998. Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling. Nature 395: 185-189.
43. Schier, A.F. and Shen, M.M. 2000. Nodal signalling in vertebrate development. Nature 403: 385-389.
44. Schier, A.F., Neuhauss, S.C., Helde, K.A., Talbot, W.S., and Driever, W. 1997. The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail. Development 124: 327-342.
45. Sen, J., Goltz, J.S., Konsolaki, M., Schupbach, T., and Stein, D. 2000. Windbeutel is required for function and correct sub-cellular localization of the Drosophila patterning protein Pipe. Development 127: 5541-5550.
46. Shimono, A. and Behringer, R.R. 1999. Isolation of novel cDNAs by subtractions between the anterior mesendoderm of single mouse gastrula stage embryos. Dev. Biol. 209: 369-380.
47. Stachel, S.E., Grunwald, D.J., and Myers, P.Z. 1993. Lithium perturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish. Development 117: 1261-1274.
48. Stainier, D.Y. 2001. Zebrafish genetics and vertebrate heart formation. Nat. Rev. Genet. 2:39-48.
49. Summerton, J. 1999. Morpholino antisense oligomers: The case for an RNase H-independent structural type. Biochim. Biophys. Acta 1489: 141-158.
50. Summerton, J. and Weller, D. 1997. Morpholino antisense oligomers: Design, preparation, and properties. Antisense Nucleic Acid Drug Dev. 7: 187-195.
51. Thisse, C. and Thisse, B. 1999. Antivin, a novel and divergent member of the TGFβ superfamily, negatively regulates mesoderm induction. Development 126: 229-240.
52. Tsukui, T., Capdevila, J., Tamura, K., Ruiz-Lozano, P., Rodriguez-Esteban, C., Yonei-Tamura, S., Magallon, J., Chandraratna, R.A., Chien, K., Blumberg, B., et al. 1999. Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1. Proc. Natl. Acad. Sci. 96: 11376-11381.
53. Turner, D.L. and Weintraub, H. 1994. Expression of achaetescute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes & Dev. 8: 1434-1447.
54. Ueno, S., Maruki, Y., Nakamura, M., Tomemori, Y., Kamae, K., Tanabe, H., Yamashita, Y., Matsuda, S., Kaneko, S., and Sano, A. 2001. The gene encoding a newly discovered protein, chorein, is mutated in chorea-acanthocytosis. Nat. Genet. 28: 121-122.
55. Weeks, D.L. and Melton, D.A. 1987. A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-beta. Cell 51: 861-867.
56. Westerfield, M. 1995. The Zebrafish Book. University of Oregon Press, Eugene, OR.
57. Yost, H.J. 1992. Regulation of vertebrate left-right asymmetries by extracellular matrix. Nature 357: 158-161.
58. Yost, H.J. 1998. Left-right development in Xenopus and zebrafish. Semin. Cell Dev. Biol. 9: 61-66.
59. Zhang, J., Talbot, W.S., and Schier, A.F. 1998. Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation. Cell 92: 241-251.
60. Zimmermann, C.R., Orr, W.C., Leclerc, R.F., Barnard, E.C., and Timberlake, W.E. 1980. Molecular cloning and selection of genes regulated in Aspergillus development. Cell 21: 709-715.