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Volumn 184, Issue 20, 2002, Pages 5533-5544

Mechanism of ToxT-dependent transcriptional activation at the Vibrio cholerae tcpA promoter

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TOXT; RNA POLYMERASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

EID: 0036786854     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.184.20.5533-5544.2002     Document Type: Article
Times cited : (46)

References (70)
  • 1
    • 0033901463 scopus 로고    scopus 로고
    • Genetic evidence that transcription activation by RhaS involves specific amino acid contacts with sigma 70
    • Bhende, P. M., and S. M. Egan. 2000. Genetic evidence that transcription activation by RhaS involves specific amino acid contacts with sigma 70. J. Bacteriol. 182:4959-4969.
    • (2000) J. Bacteriol. , vol.182 , pp. 4959-4969
    • Bhende, P.M.1    Egan, S.M.2
  • 2
    • 0030786451 scopus 로고    scopus 로고
    • DNA binding and DNA bending by the MelR transcription activator protein from Escherichia coli
    • Bourgerie, S. J., C. M. Michan, M. S. Thomas, S. J. W. Busby, and E. I. Hyde. 1997. DNA binding and DNA bending by the MelR transcription activator protein from Escherichia coli. Nucleic Acids Res. 25:1685-1693.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1685-1693
    • Bourgerie, S.J.1    Michan, C.M.2    Thomas, M.S.3    Busby, S.J.W.4    Hyde, E.I.5
  • 3
    • 0029019840 scopus 로고
    • Organization of tcp, acf, and toxT genes within a ToxT-dependent operon
    • Brown, R. C., and R. K. Taylor. 1995. Organization of tcp, acf, and toxT genes within a ToxT-dependent operon. Mol. Microbiol. 16:425-439.
    • (1995) Mol. Microbiol. , vol.16 , pp. 425-439
    • Brown, R.C.1    Taylor, R.K.2
  • 4
    • 0032454634 scopus 로고    scopus 로고
    • Analysis of cis-acting elements required for bfpA expression in enteropathogenic Escherichia coli
    • Bustamante, V. H., E. Calva, and J. L. Puente. 1998. Analysis of cis-acting elements required for bfpA expression in enteropathogenic Escherichia coli. J. Bacteriol. 180:3013-3016.
    • (1998) J. Bacteriol. , vol.180 , pp. 3013-3016
    • Bustamante, V.H.1    Calva, E.2    Puente, J.L.3
  • 5
    • 85045502002 scopus 로고
    • Randomization of genes by PCR mutagenesis
    • Cadwell, R. C., and G. Joyce. 1992. Randomization of genes by PCR mutagenesis. PCR Methods Appl. 2:26-33.
    • (1992) PCR Methods Appl. , vol.2 , pp. 26-33
    • Cadwell, R.C.1    Joyce, G.2
  • 6
    • 0030931193 scopus 로고    scopus 로고
    • Phase variation in tcpH modulates expression of the ToxR regulon in Vibrio cholerae
    • Carroll, P. A., K. T. Tashima, M. B. Rogers, V. J. DiRita, and S. B. Calderwood. 1997. Phase variation in tcpH modulates expression of the ToxR regulon in Vibrio cholerae. Mol. Microbiol. 25:1099-1111.
    • (1997) Mol. Microbiol. , vol.25 , pp. 1099-1111
    • Carroll, P.A.1    Tashima, K.T.2    Rogers, M.B.3    DiRita, V.J.4    Calderwood, S.B.5
  • 7
    • 0031015444 scopus 로고    scopus 로고
    • A branch in the ToxR regulatory cascade of Vibrio cholerae revealed by characterization of toxT mutant strains
    • Champion, G. A., M. N. Neely, M. A. Brennan, and V. J. DiRita. 1997. A branch in the ToxR regulatory cascade of Vibrio cholerae revealed by characterization of toxT mutant strains. Mol. Microbiol. 23:323-331.
    • (1997) Mol. Microbiol. , vol.23 , pp. 323-331
    • Champion, G.A.1    Neely, M.N.2    Brennan, M.A.3    DiRita, V.J.4
  • 8
    • 0028871486 scopus 로고
    • Single amino acid substitutions in the N-terminus of Vibrio cholerae TcpA affect colonization, autoagglutination and serum resistance
    • Chiang, S. L., R. K. Taylor, M. Koomey, and J. J. Mekalanos. 1995. Single amino acid substitutions in the N-terminus of Vibrio cholerae TcpA affect colonization, autoagglutination and serum resistance. Mol. Microbiol. 17: 1133-1142.
    • (1995) Mol. Microbiol. , vol.17 , pp. 1133-1142
    • Chiang, S.L.1    Taylor, R.K.2    Koomey, M.3    Mekalanos, J.J.4
  • 9
    • 0033768412 scopus 로고    scopus 로고
    • Bacterial virulence gene regulation: An evolutionary perspective
    • Cotter, P. A., and V. J. DiRita. 2000. Bacterial virulence gene regulation: an evolutionary perspective. Annu. Rev. Microbiol. 54:519-565.
    • (2000) Annu. Rev. Microbiol. , vol.54 , pp. 519-565
    • Cotter, P.A.1    DiRita, V.J.2
  • 10
    • 0031854047 scopus 로고    scopus 로고
    • Analysis of ToxR-dependent transcription activation of ompU, the gene encoding a major envelope protein in Vibrio cholerae
    • Crawford, J. A., J. B. Kaper, and V. J. DiRita. 1998. Analysis of ToxR-dependent transcription activation of ompU, the gene encoding a major envelope protein in Vibrio cholerae. Mol. Microbiol. 29:235-246.
    • (1998) Mol. Microbiol. , vol.29 , pp. 235-246
    • Crawford, J.A.1    Kaper, J.B.2    DiRita, V.J.3
  • 11
    • 0026098804 scopus 로고
    • Periplasmic interaction between two membrane regulatory proteins, ToxR and ToxS, results in signal transduction and transcriptional activation
    • DiRita, V. J., and J. J. Mekalanos. 1991. Periplasmic interaction between two membrane regulatory proteins, ToxR and ToxS, results in signal transduction and transcriptional activation. Cell 64:29-37.
    • (1991) Cell , vol.64 , pp. 29-37
    • DiRita, V.J.1    Mekalanos, J.J.2
  • 13
    • 0034461478 scopus 로고    scopus 로고
    • Transcription activation by a variety of AraC/XylS family activators does not depend on the class II-specific activation determinant in the N-terminal domain of the RNA polymerase alpha subunit
    • Egan, S. M., A. J. Pease, J. Lang, X. Li, V. Rao, W. K. Gillette, R. Ruiz, J. L. Ramos, and R. E. Wolf, Jr. 2000. Transcription activation by a variety of AraC/XylS family activators does not depend on the class II-specific activation determinant in the N-terminal domain of the RNA polymerase alpha subunit. J. Bacteriol. 182:7075-7077.
    • (2000) J. Bacteriol. , vol.182 , pp. 7075-7077
    • Egan, S.M.1    Pease, A.J.2    Lang, J.3    Li, X.4    Rao, V.5    Gillette, W.K.6    Ruiz, R.7    Ramos, J.L.8    Wolf R.E., Jr.9
  • 14
    • 0033567215 scopus 로고    scopus 로고
    • Bacterial promoter architecture: Subsite structure of UP elements and interactions with the carboxy-terminal domain of the RNA polymerase α subunit
    • Estrem, S. T., W. Ross, T. Gaal, Z. W. Chen, W. Niu, R. H. Ebright, and R. L. Gourse. 1999. Bacterial promoter architecture: subsite structure of UP elements and interactions with the carboxy-terminal domain of the RNA polymerase α subunit. Genes Dev. 13:2134-2147.
    • (1999) Genes Dev. , vol.13 , pp. 2134-2147
    • Estrem, S.T.1    Ross, W.2    Gaal, T.3    Chen, Z.W.4    Niu, W.5    Ebright, R.H.6    Gourse, R.L.7
  • 15
    • 0028312483 scopus 로고
    • The accessory colonization factor and toxin-coregulated pilus gene clusters are physically linked on the Vibrio cholerae 0395 chromosome
    • Everiss, K. D., K. J. Hughes, and K. M. Peterson. 1994. The accessory colonization factor and toxin-coregulated pilus gene clusters are physically linked on the Vibrio cholerae 0395 chromosome. DNA Seq. 5:51-55.
    • (1994) DNA Seq. , vol.5 , pp. 51-55
    • Everiss, K.D.1    Hughes, K.J.2    Peterson, K.M.3
  • 16
    • 0028816556 scopus 로고
    • Direct random mutagenesis of gene-sized DNA fragments using polymerase chain reaction
    • Fromant, M., S. Blanquet, and P. Plateau. 1995. Direct random mutagenesis of gene-sized DNA fragments using polymerase chain reaction. Anal. Biochem. 224:347-353.
    • (1995) Anal. Biochem. , vol.224 , pp. 347-353
    • Fromant, M.1    Blanquet, S.2    Plateau, P.3
  • 17
    • 0022870839 scopus 로고
    • Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector
    • Furste, J. P., W. Pansegrau, R. Frank, H. Blocker, P. Scholz, M. Bagdasarian, and E. Lanka. 1986. Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector. Gene 48:119-131.
    • (1986) Gene , vol.48 , pp. 119-131
    • Furste, J.P.1    Pansegrau, W.2    Frank, R.3    Blocker, H.4    Scholz, P.5    Bagdasarian, M.6    Lanka, E.7
  • 19
    • 0033852409 scopus 로고    scopus 로고
    • UPs and downs in bacterial transcription initiation: The role of the alpha subunit of RNA polymerase in promoter recognition
    • Gourse, R. L., W. Ross, and T. Gaal. 2000. UPs and downs in bacterial transcription initiation: the role of the alpha subunit of RNA polymerase in promoter recognition. Mol. Microbiol. 37:687-695.
    • (2000) Mol. Microbiol. , vol.37 , pp. 687-695
    • Gourse, R.L.1    Ross, W.2    Gaal, T.3
  • 20
    • 0031029971 scopus 로고    scopus 로고
    • Bile affects production of virulence factors and motility of Vibrio cholerae
    • Gupta, S., and R. Chowdhury. 1997. Bile affects production of virulence factors and motility of Vibrio cholerae. Infect. Immun. 65:1131-1134.
    • (1997) Infect. Immun. , vol.65 , pp. 1131-1134
    • Gupta, S.1    Chowdhury, R.2
  • 21
    • 0029018327 scopus 로고
    • Tight regulation, modulation and high-level expression by vectors containing the arabinose pBAD promoter
    • Guzman, L. M., D. Belin, M. J. Carson, and J. Beckwith. 1995. Tight regulation, modulation and high-level expression by vectors containing the arabinose pBAD promoter. J. Bacteriol. 177:4121-4130.
    • (1995) J. Bacteriol. , vol.177 , pp. 4121-4130
    • Guzman, L.M.1    Belin, D.2    Carson, M.J.3    Beckwith, J.4
  • 22
    • 0031930690 scopus 로고    scopus 로고
    • TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae
    • Häse, C., and J. J. Mekalanos. 1998. TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae. Proc. Natl. Acad. Sci. USA 95:730-734.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 730-734
    • Häse, C.1    Mekalanos, J.J.2
  • 23
    • 0025772728 scopus 로고
    • Functional specialization within the α-subunit of Escherichia coli RNA polymerase
    • Hayward, R. S., K. Igarashi, and A. Ishihama. 1991. Functional specialization within the α-subunit of Escherichia coli RNA polymerase. J. Mol. Biol. 221:23-29.
    • (1991) J. Mol. Biol. , vol.221 , pp. 23-29
    • Hayward, R.S.1    Igarashi, K.2    Ishihama, A.3
  • 24
    • 1842271665 scopus 로고
    • A dimer of AraC protein contacts three adjacent major groove regions of the aral DNA site
    • Hendrickson, W., and R. Schleif. 1985. A dimer of AraC protein contacts three adjacent major groove regions of the aral DNA site. Proc. Natl. Acad. Sci. USA 82:3129-3133.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 3129-3133
    • Hendrickson, W.1    Schleif, R.2
  • 25
    • 0023736046 scopus 로고
    • Toxin, toxin-co-regulated pili, and the toxR regulon are essential for Vibrio cholerae colonization in humans
    • Herrington, D. A., R. H. Hall, G. Losonsky, J. J. Mekalanos, R. K. Taylor, and M. M. Levine. 1988. Toxin, toxin-co-regulated pili, and the toxR regulon are essential for Vibrio cholerae colonization in humans. J. Exp. Med. 168: 1487-1492.
    • (1988) J. Exp. Med. , vol.168 , pp. 1487-1492
    • Herrington, D.A.1    Hall, R.H.2    Losonsky, G.3    Mekalanos, J.J.4    Taylor, R.K.5    Levine, M.M.6
  • 26
    • 0026663115 scopus 로고
    • The virulence gene activator ToxT from Vibrio cholerae is a member of the AraC family of transcriptional activators
    • Higgins, D., E. Nazareno, and V. J. DiRita. 1992. The virulence gene activator ToxT from Vibrio cholerae is a member of the AraC family of transcriptional activators. J. Bacteriol. 174:6974-6980.
    • (1992) J. Bacteriol. , vol.174 , pp. 6974-6980
    • Higgins, D.1    Nazareno, E.2    DiRita, V.J.3
  • 27
    • 0034121913 scopus 로고    scopus 로고
    • Roles of cyclic AMP receptor protein and the carboxyl-terminal domain of the α subunit in transcription activation of the Escherichia coli rhaBAD operon
    • Holcroft, C. C., and S. M. Egan. 2000. Roles of cyclic AMP receptor protein and the carboxyl-terminal domain of the α subunit in transcription activation of the Escherichia coli rhaBAD operon. J. Bacteriol. 182:3529-3535.
    • (2000) J. Bacteriol. , vol.182 , pp. 3529-3535
    • Holcroft, C.C.1    Egan, S.M.2
  • 28
    • 0034460874 scopus 로고    scopus 로고
    • Interdependence of activation at rhaSR by cyclic AMP receptor protein, the RNA polymerase alpha subunit C-terminal domain, and RhaR
    • Holcroft, C. C., and S. M. Egan. 2000. Interdependence of activation at rhaSR by cyclic AMP receptor protein, the RNA polymerase alpha subunit C-terminal domain, and RhaR. J. Bacteriol. 182:6774-6782.
    • (2000) J. Bacteriol. , vol.182 , pp. 6774-6782
    • Holcroft, C.C.1    Egan, S.M.2
  • 29
    • 0029162189 scopus 로고
    • Analyses of the DNA-binding and transcriptional activation properties of ExsA, the transcriptional activator of the Pseudomonas aeruginosa exoenzyme S regulon
    • Hovey, A., and D. Frank. 1995. Analyses of the DNA-binding and transcriptional activation properties of ExsA, the transcriptional activator of the Pseudomonas aeruginosa exoenzyme S regulon. J. Bacteriol. 177:4427-4436.
    • (1995) J. Bacteriol. , vol.177 , pp. 4427-4436
    • Hovey, A.1    Frank, D.2
  • 30
    • 0029671285 scopus 로고    scopus 로고
    • Ambidextrous transcriptional activation by SoxS: Requirement for the C-terminal domain of the RNA polymerase alpha subunit in a subset of Escherichia coli superoxide-inducible genes
    • Jair, K., W. Fawcett, N. Fujita, A. Ishihama, and R. E. Wolf, Jr. 1996. Ambidextrous transcriptional activation by SoxS: requirement for the C-terminal domain of the RNA polymerase alpha subunit in a subset of Escherichia coli superoxide-inducible genes. Mol. Microbiol. 19:307-317.
    • (1996) Mol. Microbiol. , vol.19 , pp. 307-317
    • Jair, K.1    Fawcett, W.2    Fujita, N.3    Ishihama, A.4    Wolf R.E., Jr.5
  • 31
    • 0029863748 scopus 로고    scopus 로고
    • Transcriptional activation of promoters of the superoxide and multiple antibiotic resistance regulons by Rob, a binding protein of the Escherichia coli origin of chromosomal replication
    • Jair, K., X. Yu, K. Skarstad, B. Thony, N. Fujita, A. Ishihama, and R. E. Wolf, Jr. 1996. Transcriptional activation of promoters of the superoxide and multiple antibiotic resistance regulons by Rob, a binding protein of the Escherichia coli origin of chromosomal replication. J. Bacteriol. 178:2507-2513.
    • (1996) J. Bacteriol. , vol.178 , pp. 2507-2513
    • Jair, K.1    Yu, X.2    Skarstad, K.3    Thony, B.4    Fujita, N.5    Ishihama, A.6    Wolf R.E., Jr.7
  • 32
    • 0028879546 scopus 로고
    • Purification and regulatory properties of MarA protein, a transcriptional activator of Escherichia coli multiple antibiotic and superoxide resistance promoters
    • Jair, K., R. G. Martin, J. L. Rosner, N. Fujita, A. Ishihama, and R. E. Wolf, Jr. 1995. Purification and regulatory properties of MarA protein, a transcriptional activator of Escherichia coli multiple antibiotic and superoxide resistance promoters. J. Bacteriol. 177:7100-7104.
    • (1995) J. Bacteriol. , vol.177 , pp. 7100-7104
    • Jair, K.1    Martin, R.G.2    Rosner, J.L.3    Fujita, N.4    Ishihama, A.5    Wolf R.E., Jr.6
  • 35
    • 0032798521 scopus 로고    scopus 로고
    • A Vibrio cholerae LysR homolog, AphB, cooperates with AphA at the tcpPH promoter to activate expression of the ToxR virulence cascade
    • Kovacikova, G., and K. Skorupski. 1999. A Vibrio cholerae LysR homolog, AphB, cooperates with AphA at the tcpPH promoter to activate expression of the ToxR virulence cascade. J. Bacteriol. 181:4250-4256.
    • (1999) J. Bacteriol. , vol.181 , pp. 4250-4256
    • Kovacikova, G.1    Skorupski, K.2
  • 36
    • 0001759947 scopus 로고    scopus 로고
    • Crystal structure of the Escherichia coli Rob transcription factor in complex with DNA
    • Kwon, H., M. Bennik, B. Demple, and T. Ellenberger. 2000. Crystal structure of the Escherichia coli Rob transcription factor in complex with DNA. Nat. Struct. Biol. 7:424-430.
    • (2000) Nat. Struct. Biol. , vol.7 , pp. 424-430
    • Kwon, H.1    Bennik, M.2    Demple, B.3    Ellenberger, T.4
  • 37
    • 0000632797 scopus 로고
    • TnphoA: A transposon probe for protein export signals
    • Manoil, C., and J. Beckwith. 1985. TnphoA: a transposon probe for protein export signals. Proc. Natl. Acad. Sci. USA 82:8129-8133.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 8129-8133
    • Manoil, C.1    Beckwith, J.2
  • 38
  • 39
    • 0027482287 scopus 로고
    • P22 Arc repressor: Enhanced expression of unstable mutants by addition of polar C-terminal sequences
    • Milla, M. E., B. M. Brown, and R. T. Sauer. 1993. P22 Arc repressor: enhanced expression of unstable mutants by addition of polar C-terminal sequences. Protein Sci. 2:2198-2205.
    • (1993) Protein Sci. , vol.2 , pp. 2198-2205
    • Milla, M.E.1    Brown, B.M.2    Sauer, R.T.3
  • 40
  • 41
    • 0024603180 scopus 로고
    • Identification of toxS, a regulatory gene whose product enhances ToxR-mediated activation of the cholera toxin promoter
    • Miller, V. L., V. J. DiRita, and J. J. Mekalanos. 1989. Identification of toxS, a regulatory gene whose product enhances ToxR-mediated activation of the cholera toxin promoter. J. Bacteriol. 171:1288-1293.
    • (1989) J. Bacteriol. , vol.171 , pp. 1288-1293
    • Miller, V.L.1    DiRita, V.J.2    Mekalanos, J.J.3
  • 42
    • 0542390231 scopus 로고
    • Synthesis of cholera toxin is positively regulated at the transcriptional level by ToxR
    • Miller, V. L., and J. J. Mekalanos. 1984. Synthesis of cholera toxin is positively regulated at the transcriptional level by ToxR. Proc. Natl. Acad. Sci. USA 81:3471-3475.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 3471-3475
    • Miller, V.L.1    Mekalanos, J.J.2
  • 43
    • 0023892552 scopus 로고
    • A novel suicide vector and its use in construction of insertion mutations: Osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR
    • Miller, V. L., and J. J. Mekalanos. 1988. A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR. J. Bacteriol. 170:2575-2583.
    • (1988) J. Bacteriol. , vol.170 , pp. 2575-2583
    • Miller, V.L.1    Mekalanos, J.J.2
  • 44
    • 0023667819 scopus 로고
    • Cholera toxin transcriptional activator ToxR is a transmembrane DNA binding protein
    • Miller, V. L., R. K. Taylor, and J. J. Mekalanos. 1987. Cholera toxin transcriptional activator ToxR is a transmembrane DNA binding protein. Cell 48:271-279.
    • (1987) Cell , vol.48 , pp. 271-279
    • Miller, V.L.1    Taylor, R.K.2    Mekalanos, J.J.3
  • 45
    • 0032949361 scopus 로고    scopus 로고
    • Binding site recognition by Rns, a virulence regulator in the AraC family
    • Munson, G., and J. R. Scott. 1999. Binding site recognition by Rns, a virulence regulator in the AraC family. J. Bacteriol. 181:2110-2117.
    • (1999) J. Bacteriol. , vol.181 , pp. 2110-2117
    • Munson, G.1    Scott, J.R.2
  • 46
    • 0033923860 scopus 로고    scopus 로고
    • Rns, a virulence regulator within the AraC family, requires binding sites upstream and downstream of its own promoter to function as an activator
    • Munson, G., and J. R. Scott. 2000. Rns, a virulence regulator within the AraC family, requires binding sites upstream and downstream of its own promoter to function as an activator. Mol. Microbiol. 36:1391-1402.
    • (2000) Mol. Microbiol. , vol.36 , pp. 1391-1402
    • Munson, G.1    Scott, J.R.2
  • 47
    • 0034019456 scopus 로고    scopus 로고
    • Classical and El Tor biotypes of Vibrio cholerae differ in timing of transcription of tcpPH during growth in inducing conditions
    • Murley, Y., J. Behari, R. Griffin, and S. B. Calderwood. 2000. Classical and El Tor biotypes of Vibrio cholerae differ in timing of transcription of tcpPH during growth in inducing conditions. Infect. Immun. 68: 3010-3014.
    • (2000) Infect. Immun. , vol.68 , pp. 3010-3014
    • Murley, Y.1    Behari, J.2    Griffin, R.3    Calderwood, S.B.4
  • 48
    • 0030582731 scopus 로고    scopus 로고
    • How AraC interacts specifically with its target DNAs
    • Niland, P., R. Huhne, and B. Muller-Hill. 1996. How AraC interacts specifically with its target DNAs. J. Mol. Biol. 264:667-674.
    • (1996) J. Mol. Biol. , vol.264 , pp. 667-674
    • Niland, P.1    Huhne, R.2    Muller-Hill, B.3
  • 49
    • 0033941006 scopus 로고    scopus 로고
    • Vibrio cholerae H-NS silences virulence gene expression at multiple steps in the ToxR regulatory cascade
    • Nye, M. B., J. D. Pfau, K. Skorupski, and R. K. Taylor. 2000. Vibrio cholerae H-NS silences virulence gene expression at multiple steps in the ToxR regulatory cascade. J. Bacteriol. 182:4295-4303.
    • (2000) J. Bacteriol. , vol.182 , pp. 4295-4303
    • Nye, M.B.1    Pfau, J.D.2    Skorupski, K.3    Taylor, R.K.4
  • 50
    • 0026716001 scopus 로고
    • Homology of TcpN, a putative regulatory protein of Vibrio cholerae, to the AraC family of transcriptional activators
    • Ogierman, M., and P. Manning. 1992. Homology of TcpN, a putative regulatory protein of Vibrio cholerae, to the AraC family of transcriptional activators. Gene 116:93-97.
    • (1992) Gene , vol.116 , pp. 93-97
    • Ogierman, M.1    Manning, P.2
  • 51
    • 0029864635 scopus 로고    scopus 로고
    • Genetic footprint of the ToxR-binding site in the promoter for cholera toxin
    • Pfau, J. D., and R. K. Taylor. 1996. Genetic footprint of the ToxR-binding site in the promoter for cholera toxin. Mol. Microbiol. 20:213-222.
    • (1996) Mol. Microbiol. , vol.20 , pp. 213-222
    • Pfau, J.D.1    Taylor, R.K.2
  • 52
    • 0031753364 scopus 로고    scopus 로고
    • Mutations in toxR and toxS that separate transcriptional activation from DNA binding at the cholera toxin gene promoter
    • Pfau, J. D., and R. K. Taylor. 1998. Mutations in toxR and toxS that separate transcriptional activation from DNA binding at the cholera toxin gene promoter. J. Bacteriol. 180:4724-4733.
    • (1998) J. Bacteriol. , vol.180 , pp. 4724-4733
    • Pfau, J.D.1    Taylor, R.K.2
  • 54
    • 0034730163 scopus 로고    scopus 로고
    • Altered expression of the ToxR-regulated porins OmpU and OmpT diminishes Vibrio cholerae bile resistance, virulence factor expression, and intestinal colonization
    • Provenzano, D., and K. E. Klose. 2000. Altered expression of the ToxR-regulated porins OmpU and OmpT diminishes Vibrio cholerae bile resistance, virulence factor expression, and intestinal colonization. Proc. Natl. Acad. Sci. USA 97:10220-10224.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10220-10224
    • Provenzano, D.1    Klose, K.E.2
  • 55
    • 0032169864 scopus 로고    scopus 로고
    • A novel DNA-binding motif in MarA: The first structure for an AraC family transcriptional activator
    • Rhee, S., R. Martin, J. Rosner, and D. Davies. 1998. A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator. Proc. Natl. Acad. Sci. USA 95:10413-10418.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10413-10418
    • Rhee, S.1    Martin, R.2    Rosner, J.3    Davies, D.4
  • 56
    • 0035793962 scopus 로고    scopus 로고
    • Interactions of the XylS regulators with the C-terminal domain of the RNA polymerase alpha subunit influence the expression level from the cognate Pm promoter
    • Ruiz, R., J. L. Ramos, and S. M. Egan. 2001. Interactions of the XylS regulators with the C-terminal domain of the RNA polymerase alpha subunit influence the expression level from the cognate Pm promoter. FEBS Lett. 491:207-211.
    • (2001) FEBS Lett. , vol.491 , pp. 207-211
    • Ruiz, R.1    Ramos, J.L.2    Egan, S.M.3
  • 57
    • 0032987096 scopus 로고    scopus 로고
    • Environmental signals modulate ToxT-dependent virulence factor expression in Vibrio cholerae
    • Schuhmacher, D. A., and K. E. Klose. 1999. Environmental signals modulate ToxT-dependent virulence factor expression in Vibrio cholerae. J. Bacteriol. 181:1508-1514.
    • (1999) J. Bacteriol. , vol.181 , pp. 1508-1514
    • Schuhmacher, D.A.1    Klose, K.E.2
  • 59
    • 0023255472 scopus 로고
    • Improved single and multicopy lac-based cloning vectors for protein and operon fusions
    • Simons, R. W., F. Houman, and N. Kleckner. 1987. Improved single and multicopy lac-based cloning vectors for protein and operon fusions. Gene 53:85-96.
    • (1987) Gene , vol.53 , pp. 85-96
    • Simons, R.W.1    Houman, F.2    Kleckner, N.3
  • 60
    • 0030885341 scopus 로고    scopus 로고
    • Control of the ToxR virulence regulon in Vibrio cholerae by environmental stimuli
    • Skorupski, K., and R. K. Taylor. 1997. Control of the ToxR virulence regulon in Vibrio cholerae by environmental stimuli. Mol. Microbiol. 25: 1003-1009.
    • (1997) Mol. Microbiol. , vol.25 , pp. 1003-1009
    • Skorupski, K.1    Taylor, R.K.2
  • 61
    • 0031023354 scopus 로고    scopus 로고
    • Cyclic AMP and its receptor protein negatively regulate the coordinate expression of cholera toxin and toxin-coregulated pilus in Vibrio cholerae
    • Skorupski, K., and R. K. Taylor. 1997. Cyclic AMP and its receptor protein negatively regulate the coordinate expression of cholera toxin and toxin-coregulated pilus in Vibrio cholerae. Proc. Natl. Acad. Sci. USA 94:265-270.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 265-270
    • Skorupski, K.1    Taylor, R.K.2
  • 62
    • 0032961294 scopus 로고    scopus 로고
    • A new level in the Vibrio cholerae ToxR virulence cascade: AphA is required for transcriptional activation of the tcpPH operon
    • Skorupski, K., and R. K. Taylor. 1999. A new level in the Vibrio cholerae ToxR virulence cascade: AphA is required for transcriptional activation of the tcpPH operon. Mol. Microbiol. 31:763-771.
    • (1999) Mol. Microbiol. , vol.31 , pp. 763-771
    • Skorupski, K.1    Taylor, R.K.2
  • 63
    • 0039391898 scopus 로고
    • Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin
    • Taylor, R. K., V. L. Miller, D. B. Furlong, and J. J. Mekalanos. 1987. Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin. Proc. Natl. Acad. Sci. USA 84:2833-2837.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 2833-2837
    • Taylor, R.K.1    Miller, V.L.2    Furlong, D.B.3    Mekalanos, J.J.4
  • 64
    • 0024524477 scopus 로고
    • Broad-host-range vectors for delivery of TnphoA: Use in genetic analysis of secreted virulence determinants of Vibrio cholerae
    • Taylor, R. K., C. Manoil, and J. J. Mekalanos. 1989. Broad-host-range vectors for delivery of TnphoA: use in genetic analysis of secreted virulence determinants of Vibrio cholerae. J. Bacteriol. 171:1870-1878.
    • (1989) J. Bacteriol. , vol.171 , pp. 1870-1878
    • Taylor, R.K.1    Manoil, C.2    Mekalanos, J.J.3
  • 65
    • 0033023573 scopus 로고    scopus 로고
    • Identification of UreR binding sites in the Enterobacteriaceae plasmid-encoded and Proteus mirabilis urease gene operons
    • Thomas, V. J., and C. M. Collins. 1999. Identification of UreR binding sites in the Enterobacteriaceae plasmid-encoded and Proteus mirabilis urease gene operons. Mol. Microbiol. 31:1417-1428.
    • (1999) Mol. Microbiol. , vol.31 , pp. 1417-1428
    • Thomas, V.J.1    Collins, C.M.2
  • 66
    • 0029849368 scopus 로고    scopus 로고
    • Cloning and characterization of bfpTVW, genes required for the transcriptional activation of bfpA in enteropathogenic Escherichia coli
    • Tobe, T., G. K. Schoolnik, I. Sohel, V. H. Bustamante, and J. L. Puente. 1996. Cloning and characterization of bfpTVW, genes required for the transcriptional activation of bfpA in enteropathogenic Escherichia coli. Mol. Microbiol. 21:963-975.
    • (1996) Mol. Microbiol. , vol.21 , pp. 963-975
    • Tobe, T.1    Schoolnik, G.K.2    Sohel, I.3    Bustamante, V.H.4    Puente, J.L.5
  • 67
    • 0033011422 scopus 로고    scopus 로고
    • Bacterial transcription factors involved in global regulation
    • Vicente, M., K. Chater, and V. de Lorenzo. 1999. Bacterial transcription factors involved in global regulation. Mol. Microbiol. 33:8-17.
    • (1999) Mol. Microbiol. , vol.33 , pp. 8-17
    • Vicente, M.1    Chater, K.2    De Lorenzo, V.3
  • 68
    • 0030057090 scopus 로고    scopus 로고
    • Lysogenic conversion by a filamentous phage encoding cholera toxin
    • Waldor, M. K., and J. J. Mekalanos. 1996. Lysogenic conversion by a filamentous phage encoding cholera toxin. Science 272:1910-1914.
    • (1996) Science , vol.272 , pp. 1910-1914
    • Waldor, M.K.1    Mekalanos, J.J.2
  • 69
    • 0036195527 scopus 로고    scopus 로고
    • Regulation of gene expression in Vibrio cholerae by ToxT involves both antirepression and RNA polymerase stimulation
    • Yu, R., and V. J. DiRita. 2002. Regulation of gene expression in Vibrio cholerae by ToxT involves both antirepression and RNA polymerase stimulation. Mol. Microbiol. 43:119-134.
    • (2002) Mol. Microbiol. , vol.43 , pp. 119-134
    • Yu, R.1    DiRita, V.J.2
  • 70
    • 0032939638 scopus 로고    scopus 로고
    • Analysis of an autoregulatory loop controlling ToxT, cholera toxin, and toxin-coregulated pilus production in Vibrio cholerae
    • Yu, R., and V. J. DiRita. 1999. Analysis of an autoregulatory loop controlling ToxT, cholera toxin, and toxin-coregulated pilus production in Vibrio cholerae. J. Bacteriol. 181:2584-2592.
    • (1999) J. Bacteriol. , vol.181 , pp. 2584-2592
    • Yu, R.1    DiRita, V.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.