-
1
-
-
0025740667
-
Type 1 fimbriae mutants of Escherichia coli K12: Characterization of recognized afimbriate strains and construction of new fim deletion mutants
-
Blomfield, I.C., McClain, M.S., and Eisenstein, B.I. (1991) Type 1 fimbriae mutants of Escherichia coli K12: characterization of recognized afimbriate strains and construction of new fim deletion mutants. Mol Microbiol 5: 1439-1445.
-
(1991)
Mol Microbiol
, vol.5
, pp. 1439-1445
-
-
Blomfield, I.C.1
McClain, M.S.2
Eisenstein, B.I.3
-
2
-
-
0028855911
-
Synergisitic binding of RNA polymerase and BvgA Phosphate to the pertusis toxin promoter of Bordetella pertussis
-
Boucher, P.E., and Stibitz, S. (1995) Synergisitic binding of RNA polymerase and BvgA Phosphate to the pertusis toxin promoter of Bordetella pertussis. J Bacteriol 177: 6486-6491.
-
(1995)
J Bacteriol
, vol.177
, pp. 6486-6491
-
-
Boucher, P.E.1
Stibitz, S.2
-
3
-
-
0031053471
-
Nature of DNA binding and RNA polymerase interaction of the Bordetella pertussis BvgA transcriptional activator at the fha promoter
-
Boucher, P.E., Murakami, K., Ishihama, A., and Stibitz, S. (1997) Nature of DNA binding and RNA polymerase interaction of the Bordetella pertussis BvgA transcriptional activator at the fha promoter. J Bacteriol 179: 1755-1763.
-
(1997)
J Bacteriol
, vol.179
, pp. 1755-1763
-
-
Boucher, P.E.1
Murakami, K.2
Ishihama, A.3
Stibitz, S.4
-
4
-
-
0029019840
-
Organization of the tcp, acf, and toxT genes within a ToxT-dependent operon
-
Brown, R.C., and Taylor, R.K. (1995) Organization of the tcp, acf, and toxT genes within a ToxT-dependent operon. Mol Microbiol 16: 425-439.
-
(1995)
Mol Microbiol
, vol.16
, pp. 425-439
-
-
Brown, R.C.1
Taylor, R.K.2
-
5
-
-
0030931193
-
Phase variation in tcpH modulates expression of the ToxR regulon in Vibrio cholerae
-
Carroll, P.A., Tashima, K.T., Rogers, M.B., DiRita, V.J., and Calderwood, S.B. (1997) Phase variation in tcpH modulates expression of the ToxR regulon in Vibrio cholerae. Mol Microbiol 25: 1099-1111.
-
(1997)
Mol Microbiol
, vol.25
, pp. 1099-1111
-
-
Carroll, P.A.1
Tashima, K.T.2
Rogers, M.B.3
DiRita, V.J.4
Calderwood, S.B.5
-
6
-
-
0030048933
-
Porins of Vibrio cholerae: Purification and characterization of OmpU
-
Chakrabarti, S.R., Chaudhuri, K., Sen, K., and Das, J. (1996) Porins of Vibrio cholerae: purification and characterization of OmpU. J Bacteriol 178: 524-530.
-
(1996)
J Bacteriol
, vol.178
, pp. 524-530
-
-
Chakrabarti, S.R.1
Chaudhuri, K.2
Sen, K.3
Das, J.4
-
7
-
-
0031015444
-
A branch in the ToxR regulatory cascade of Vibrio cholerae revealed by characterization of toxT mutant strains
-
Champion, G.A., Neely, M.N., Brennan, M.A., and DiRita, V.J. (1997) A branch in the ToxR regulatory cascade of Vibrio cholerae revealed by characterization of toxT mutant strains. Mol Microbiol 23: 323-331.
-
(1997)
Mol Microbiol
, vol.23
, pp. 323-331
-
-
Champion, G.A.1
Neely, M.N.2
Brennan, M.A.3
DiRita, V.J.4
-
8
-
-
0017807890
-
Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid
-
Chang, A.C.Y., and Cohen, S.N. (1978) Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. J Bacteriol 134: 1141-1156.
-
(1978)
J Bacteriol
, vol.134
, pp. 1141-1156
-
-
Chang, A.C.Y.1
Cohen, S.N.2
-
9
-
-
0026519517
-
Co-ordinate expression of virulence genes by ToxR in Vibrio cholerae
-
DiRita, V.J. (1992) Co-ordinate expression of virulence genes by ToxR in Vibrio cholerae. Mol Microbiol 6: 451-458.
-
(1992)
Mol Microbiol
, vol.6
, pp. 451-458
-
-
DiRita, V.J.1
-
10
-
-
0026098804
-
Periplasmic interaction between two membrane regulatory proteins, ToxR and ToxS, results in signal transduction and transcriptional activation
-
DiRita, V.J., and Mekalanos, J.J. (1991) Periplasmic interaction between two membrane regulatory proteins, ToxR and ToxS, results in signal transduction and transcriptional activation. Cell 64: 29-37.
-
(1991)
Cell
, vol.64
, pp. 29-37
-
-
DiRita, V.J.1
Mekalanos, J.J.2
-
11
-
-
0025992961
-
Regulatory cascade controls virulence in Vibrio cholerae
-
DiRita, V.J., Parsot, C., Jander, G., and Mekalanos, J.J. (1991) Regulatory cascade controls virulence in Vibrio cholerae. Proc Natl Acad Sci USA 88: 5403-5407.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 5403-5407
-
-
DiRita, V.J.1
Parsot, C.2
Jander, G.3
Mekalanos, J.J.4
-
12
-
-
0029848941
-
Differential expression of the ToxR regulon in classical and El Tor biotypes of Vibrio cholerae is due to biotype-specific control over toxT expression
-
DiRita, V.J., Neely, M., Taylor, R.K., and Bruss, P.M. (1996) Differential expression of the ToxR regulon in classical and El Tor biotypes of Vibrio cholerae is due to biotype-specific control over toxT expression. Proc Natl Acad Sci USA 93: 7991-7995.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7991-7995
-
-
DiRita, V.J.1
Neely, M.2
Taylor, R.K.3
Bruss, P.M.4
-
13
-
-
0028001591
-
Analysis of membrane protein interaction: ToxR can dimerize the amino terminus of phage lambda repressor
-
Dziejman, M., and Mekalanos, J.J. (1994) Analysis of membrane protein interaction: ToxR can dimerize the amino terminus of phage lambda repressor. Mol Microbiol 13: 485-494.
-
(1994)
Mol Microbiol
, vol.13
, pp. 485-494
-
-
Dziejman, M.1
Mekalanos, J.J.2
-
14
-
-
0026525553
-
A method for constructing single-copy lac fusions in Salmonella typhimurium and its application to the hemA-prfA operon
-
Elliott, T. (1992) A method for constructing single-copy lac fusions in Salmonella typhimurium and its application to the hemA-prfA operon. J Bacteriol 174: 245-253.
-
(1992)
J Bacteriol
, vol.174
, pp. 245-253
-
-
Elliott, T.1
-
15
-
-
0027963434
-
The Vibrio cholerae acfB colonization determinant encodes an inner membrane protein that is related to a family of signal-transducing proteins
-
Everiss, K.D., Hughes, K.J., Kovach, M.E., and Peterson, K.M. (1994) The Vibrio cholerae acfB colonization determinant encodes an inner membrane protein that is related to a family of signal-transducing proteins. Infect Immun 62: 3289-3298.
-
(1994)
Infect Immun
, vol.62
, pp. 3289-3298
-
-
Everiss, K.D.1
Hughes, K.J.2
Kovach, M.E.3
Peterson, K.M.4
-
16
-
-
0028073817
-
Sequence elements responsible for DNA curvature
-
Haran, T.E., Kahn, J.D., and Crothers, D.M. (1994) Sequence elements responsible for DNA curvature. J Mol Biol 244: 135-143.
-
(1994)
J Mol Biol
, vol.244
, pp. 135-143
-
-
Haran, T.E.1
Kahn, J.D.2
Crothers, D.M.3
-
17
-
-
0031930690
-
TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae
-
Häse, C.C., and Mekalanos, J.J. (1998) TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae. Proc Natl Acad Sci USA 95: 730-734.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 730-734
-
-
Häse, C.C.1
Mekalanos, J.J.2
-
18
-
-
0023736046
-
Toxin, toxin-coregulated pili, and the ToxR regulon are essential for Vibrio cholerae pathogenesis in humans
-
Herrington, D.A., Hall, R.H., Losonsky, G., Mekalanos, J.J., Taylor, R.K., and Levine, M.M. (1988) Toxin, toxin-coregulated pili, and the ToxR regulon are essential for Vibrio cholerae pathogenesis in humans. J Exp Med 168: 1487-1492.
-
(1988)
J Exp Med
, vol.168
, pp. 1487-1492
-
-
Herrington, D.A.1
Hall, R.H.2
Losonsky, G.3
Mekalanos, J.J.4
Taylor, R.K.5
Levine, M.M.6
-
19
-
-
0026663115
-
The virulence gene activator ToxT from Vibrio cholerae is a member of the AraC family of transcriptional activators
-
Higgins, D.E., Nazareno, E., and DiRita, V.J. (1992) The virulence gene activator ToxT from Vibrio cholerae is a member of the AraC family of transcriptional activators. J Bacteriol 174: 6974-6980.
-
(1992)
J Bacteriol
, vol.174
, pp. 6974-6980
-
-
Higgins, D.E.1
Nazareno, E.2
DiRita, V.J.3
-
20
-
-
0028027746
-
Transcriptional control of toxT, a regulatory gene in the ToxR regulon of Vibrio cholerae
-
Higgins, D.E., and DiRita, V.J. (1994) Transcriptional control of toxT, a regulatory gene in the ToxR regulon of Vibrio cholerae. Mol Microbiol 14: 17-29.
-
(1994)
Mol Microbiol
, vol.14
, pp. 17-29
-
-
Higgins, D.E.1
DiRita, V.J.2
-
21
-
-
0030029878
-
Genetic analysis of the interaction between Vibrio cholerae transcription activator ToxR and toxT promoter DNA
-
Higgins, D.E., and DiRita, V.J. (1996) Genetic analysis of the interaction between Vibrio cholerae transcription activator ToxR and toxT promoter DNA. J Bacteriol 178: 1080-1087.
-
(1996)
J Bacteriol
, vol.178
, pp. 1080-1087
-
-
Higgins, D.E.1
DiRita, V.J.2
-
22
-
-
0030580087
-
Identification of the bases in the ompF regulatory region, which interact with the transcription factor OmpR
-
Huang, K.-J., and Igo, M.M. (1996) Identification of the bases in the ompF regulatory region, which interact with the transcription factor OmpR. J Mol Biol 262: 615-628.
-
(1996)
J Mol Biol
, vol.262
, pp. 615-628
-
-
Huang, K.-J.1
Igo, M.M.2
-
23
-
-
0027965333
-
Sequence analysis of the Vibrio cholerae acfD gene reveals the presence of an overlapping reading frame, orfZ, which encodes a protein that shares sequence similarity to the FliA and FliC products of Salmonella
-
Hughes, K.J., Everiss, K.D., Kovach, M.E., and Peterson, K.M. (1994) Sequence analysis of the Vibrio cholerae acfD gene reveals the presence of an overlapping reading frame, orfZ, which encodes a protein that shares sequence similarity to the FliA and FliC products of Salmonella. Gene 146: 79-82.
-
(1994)
Gene
, vol.146
, pp. 79-82
-
-
Hughes, K.J.1
Everiss, K.D.2
Kovach, M.E.3
Peterson, K.M.4
-
24
-
-
0028928563
-
Isolation and characterization of the Vibrio cholerae acfA gene, required for efficient intestinal colonization
-
Hughes, K.J., Everiss, K.D., Kovach, M.E., and Peterson, K.M. (1995) Isolation and characterization of the Vibrio cholerae acfA gene, required for efficient intestinal colonization. Gene 156: 59-61.
-
(1995)
Gene
, vol.156
, pp. 59-61
-
-
Hughes, K.J.1
Everiss, K.D.2
Kovach, M.E.3
Peterson, K.M.4
-
25
-
-
0028855105
-
Cholera
-
Kaper, J.B., Morris, J.G., Jr., and Levine, M.M. (1995) Cholera. Clin Microbiol Rev 8: 48-86.
-
(1995)
Clin Microbiol Rev
, vol.8
, pp. 48-86
-
-
Kaper, J.B.1
Morris Jr., J.G.2
Levine, M.M.3
-
26
-
-
0029823811
-
A putative integrase gene defines the distal end of a large cluster of ToxR-regulated colonization genes in Vibrio cholerae
-
Kovach, M.E., Shaffer, M.D., and Peterson, K.M. (1996) A putative integrase gene defines the distal end of a large cluster of ToxR-regulated colonization genes in Vibrio cholerae. Microbiology 142: 2165-2174.
-
(1996)
Microbiology
, vol.142
, pp. 2165-2174
-
-
Kovach, M.E.1
Shaffer, M.D.2
Peterson, K.M.3
-
27
-
-
0027166658
-
Vibrio parahaemolyticus has a homolog of the Vibrio cholerae toxRS operon that mediates environmentally induced regulation of the thermostable direct hemolysin gene
-
Lin, Z., Kumagai, K., Baba, K., Mekalanos, J.J., and Nishibuchi, M. (1993) Vibrio parahaemolyticus has a homolog of the Vibrio cholerae toxRS operon that mediates environmentally induced regulation of the thermostable direct hemolysin gene. J Bacteriol 175: 3844-3855.
-
(1993)
J Bacteriol
, vol.175
, pp. 3844-3855
-
-
Lin, Z.1
Kumagai, K.2
Baba, K.3
Mekalanos, J.J.4
Nishibuchi, M.5
-
28
-
-
0025037615
-
Improved vector system for constructing transcriptional fusions that ensure independent translation of lacZ
-
Linn, T., and Pierre, R.S. (1990) Improved vector system for constructing transcriptional fusions that ensure independent translation of lacZ. J Bacteriol 172: 1077-1084.
-
(1990)
J Bacteriol
, vol.172
, pp. 1077-1084
-
-
Linn, T.1
Pierre, R.S.2
-
29
-
-
0031568318
-
The DNA-binding domain of OmpR: Crystal structure of a winged helix transcription factor
-
Martínez-Hackert, E., and Stock, A.M. (1997) The DNA-binding domain of OmpR: crystal structure of a winged helix transcription factor. Struct 5: 109-124.
-
(1997)
Struct
, vol.5
, pp. 109-124
-
-
Martínez-Hackert, E.1
Stock, A.M.2
-
30
-
-
0003785155
-
-
Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
-
Miller, J.H. (1972) Experiments in Molecular Genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
-
(1972)
Experiments in Molecular Genetics
-
-
Miller, J.H.1
-
31
-
-
0542390231
-
Synthesis of cholera toxin is positively regulated at the transcriptional level by ToxR
-
Miller, V.L., and Mekalanos, J.J. (1984) Synthesis of cholera toxin is positively regulated at the transcriptional level by ToxR. Proc Natl Acad Sci USA 81: 3471-3475.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 3471-3475
-
-
Miller, V.L.1
Mekalanos, J.J.2
-
32
-
-
0023892552
-
A novel suicide vector and its use in construction of insertion mutations: Osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR
-
Miller, V.L., and Mekalanos, J.J. (1988) A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR. J Bacteriol 170: 2575-2583.
-
(1988)
J Bacteriol
, vol.170
, pp. 2575-2583
-
-
Miller, V.L.1
Mekalanos, J.J.2
-
33
-
-
0023667819
-
Cholera toxin transcriptional activator ToxR is a transmembrane DNA binding protein
-
Miller, V.L., Taylor, R.K., and Mekalanos, J.J. (1987) Cholera toxin transcriptional activator ToxR is a transmembrane DNA binding protein. Cell 48: 271-279.
-
(1987)
Cell
, vol.48
, pp. 271-279
-
-
Miller, V.L.1
Taylor, R.K.2
Mekalanos, J.J.3
-
34
-
-
0024603180
-
Identification of toxS, a regulatory gene whose product enhances ToxR-mediated activation of the cholera toxin promoter
-
Miller, V.L., DiRita, V.J., and Mekalanos, J.J. (1989) Identification of toxS, a regulatory gene whose product enhances ToxR-mediated activation of the cholera toxin promoter. J Bacteriol 171: 1288-1293.
-
(1989)
J Bacteriol
, vol.171
, pp. 1288-1293
-
-
Miller, V.L.1
DiRita, V.J.2
Mekalanos, J.J.3
-
35
-
-
0028229613
-
Roles of LysP and CadC in mediating the lysine requirement for acid induction of the Escherichia coli cad operon
-
Neely, M.N., Dell, C.L., and Olson, E.R. (1994) Roles of LysP and CadC in mediating the lysine requirement for acid induction of the Escherichia coli cad operon. J Bacteriol 176: 3278-3285.
-
(1994)
J Bacteriol
, vol.176
, pp. 3278-3285
-
-
Neely, M.N.1
Dell, C.L.2
Olson, E.R.3
-
36
-
-
0026715095
-
ToxR proteins with substitutions in residues conserved with OmpR fail to activate transcription from the cholera toxin promoter
-
Ottemann, K.M., DiRita, V.J., and Mekalanos, J.J. (1992) ToxR proteins with substitutions in residues conserved with OmpR fail to activate transcription from the cholera toxin promoter. J Bacteriol 174: 6807-6814.
-
(1992)
J Bacteriol
, vol.174
, pp. 6807-6814
-
-
Ottemann, K.M.1
DiRita, V.J.2
Mekalanos, J.J.3
-
37
-
-
0023700080
-
Characterization of the Vibrio cholerae ToxR regulon: Identification of novel genes involved in intestinal colonization
-
published erratum appears in Infect Immun 1989 Feb 57 (2): 660
-
Peterson, K.M., and Mekalanos, J.J. (1988) Characterization of the Vibrio cholerae ToxR regulon: identification of novel genes involved in intestinal colonization [published erratum appears in Infect Immun 1989 Feb 57 (2): 660]. Infect Immun 56: 2822-2829.
-
(1988)
Infect Immun
, vol.56
, pp. 2822-2829
-
-
Peterson, K.M.1
Mekalanos, J.J.2
-
38
-
-
0029864635
-
Genetic footprint of the ToxR-binding site in the promoter for cholera toxin
-
Pfau, J.D., and Taylor, R.K. (1996) Genetic footprint of the ToxR-binding site in the promoter for cholera toxin. Mol Microbiol 20: 213-222.
-
(1996)
Mol Microbiol
, vol.20
, pp. 213-222
-
-
Pfau, J.D.1
Taylor, R.K.2
-
39
-
-
0029157823
-
Identification of base pairs important for OmpR-DNA interaction
-
Pratt, L.A., and Silhavy, T.J. (1996) Identification of base pairs important for OmpR-DNA interaction. Mol Microbiol 17: 565-573.
-
(1996)
Mol Microbiol
, vol.17
, pp. 565-573
-
-
Pratt, L.A.1
Silhavy, T.J.2
-
40
-
-
0028238190
-
The light organ symbiont Vibrio fischeri possesses a homolog of the Vibrio cholerae transmembrane transcriptional activator ToxR
-
Reich, K.A., and Schoolnik, G.K. (1994) The light organ symbiont Vibrio fischeri possesses a homolog of the Vibrio cholerae transmembrane transcriptional activator ToxR. J Bacteriol 176: 3085-3088.
-
(1994)
J Bacteriol
, vol.176
, pp. 3085-3088
-
-
Reich, K.A.1
Schoolnik, G.K.2
-
41
-
-
0004136246
-
-
Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
-
Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: a Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
-
(1989)
Molecular Cloning: A Laboratory Manual
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
42
-
-
0023255472
-
Improved single and multicopy lac-based cloning vectors for protein and operon fusions
-
Simons, R.W., Houman, F., and Kleckner, N. (1987) Improved single and multicopy lac-based cloning vectors for protein and operon fusions. Gene 53: 85-96.
-
(1987)
Gene
, vol.53
, pp. 85-96
-
-
Simons, R.W.1
Houman, F.2
Kleckner, N.3
-
43
-
-
0028857075
-
The OmpU outer membrane protein, a potential adherence factor Vibrio cholerae
-
Sperandio, V., Giron, J.A., Silveira, W.D., and Kaper, J.B. (1995) The OmpU outer membrane protein, a potential adherence factor Vibrio cholerae. Infect Immun 63: 4433-4438.
-
(1995)
Infect Immun
, vol.63
, pp. 4433-4438
-
-
Sperandio, V.1
Giron, J.A.2
Silveira, W.D.3
Kaper, J.B.4
-
44
-
-
0029805946
-
Cloning and characterization of the gene encoding the OmpU outer membrane protein of Vibrio cholerae
-
Sperandio, V., Bailey, C., Girón, J.A., DiRita, V.J., Silveira, W.D., Vettore, A.L., and Kaper, J.B. (1996) Cloning and characterization of the gene encoding the OmpU outer membrane protein of Vibrio cholerae. Infect Immun 64: 5406-5409.
-
(1996)
Infect Immun
, vol.64
, pp. 5406-5409
-
-
Sperandio, V.1
Bailey, C.2
Girón, J.A.3
DiRita, V.J.4
Silveira, W.D.5
Vettore, A.L.6
Kaper, J.B.7
-
45
-
-
0028446567
-
DNA recognition by DNase I
-
Suck, D. (1994) DNA recognition by DNase I. J Mol Recog 7: 65-70.
-
(1994)
J Mol Recog
, vol.7
, pp. 65-70
-
-
Suck, D.1
-
46
-
-
0039391898
-
Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin
-
Taylor, R.K., Miller, V.L., Furlong, D.B., and Mekalanos, J.J. (1987) Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin. Proc Natl Acad Sci USA 84: 2833-2837.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 2833-2837
-
-
Taylor, R.K.1
Miller, V.L.2
Furlong, D.B.3
Mekalanos, J.J.4
-
47
-
-
0030057090
-
Lysogenic conversion by a filamentous phage encoding cholera toxin
-
Waldor, M.K., and Mekalanos, J.J. (1996) Lysogenic conversion by a filamentous phage encoding cholera toxin. Science 272: 1910-1914.
-
(1996)
Science
, vol.272
, pp. 1910-1914
-
-
Waldor, M.K.1
Mekalanos, J.J.2
-
48
-
-
0031779823
-
Identification of a regulatory protein required for pressure-responsive gene expression in the deep-sea bacterium Photobacterium strain SS9
-
Welch, T., and Bartlett, D.H. (1998) Identification of a regulatory protein required for pressure-responsive gene expression in the deep-sea bacterium Photobacterium strain SS9. Mol Microbiol 27: 977-985.
-
(1998)
Mol Microbiol
, vol.27
, pp. 977-985
-
-
Welch, T.1
Bartlett, D.H.2
-
49
-
-
0030915670
-
Transcriptional regulation of the Yersinia pseudotuberculosis pH 6 antigen adhesin by two envelope-associated components
-
Yang, Y., and Isberg, R.R. (1997) Transcriptional regulation of the Yersinia pseudotuberculosis pH 6 antigen adhesin by two envelope-associated components. Mol Microbiol 24: 499-510.
-
(1997)
Mol Microbiol
, vol.24
, pp. 499-510
-
-
Yang, Y.1
Isberg, R.R.2
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