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Volumn 25, Issue 6, 1997, Pages 1099-1111

Phase variation in tcpH modulates expression of the ToxR regulon in Vibrio cholerae

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA TOXIN; VIRULENCE FACTOR;

EID: 0030931193     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1997.5371901.x     Document Type: Article
Times cited : (114)

References (43)
  • 1
    • 0029019840 scopus 로고
    • Organization of tcp, acf, and toxT genes within a ToxT-dependent operon
    • Brown, B.C., and Taylor, R.K. (1995) Organization of tcp, acf, and toxT genes within a ToxT-dependent operon. Mol Microbiol 16: 425-439.
    • (1995) Mol Microbiol , vol.16 , pp. 425-439
    • Brown, B.C.1    Taylor, R.K.2
  • 2
    • 0031024275 scopus 로고    scopus 로고
    • Antigenic variation in Neisseria gonorrhoeae: Production of multiple lipooligosaccharides
    • Burch, C.L., Danaher, R.J., and Stein, D.C. (1997) Antigenic variation in Neisseria gonorrhoeae: Production of multiple lipooligosaccharides. J Bacteriol 179: 982-986.
    • (1997) J Bacteriol , vol.179 , pp. 982-986
    • Burch, C.L.1    Danaher, R.J.2    Stein, D.C.3
  • 3
    • 0026748433 scopus 로고
    • Cloning, sequencing, and transcriptional regulation of viuA, the gene encoding the ferric vibriobactin receptor of Vibrio cholerae
    • Butterton, J.R., Stoebner, J.A., Payne, S.M., and Calderwood, S.B. (1992) Cloning, sequencing, and transcriptional regulation of viuA, the gene encoding the ferric vibriobactin receptor of Vibrio cholerae. J Bacteriol 174: 3729-3738.
    • (1992) J Bacteriol , vol.174 , pp. 3729-3738
    • Butterton, J.R.1    Stoebner, J.A.2    Payne, S.M.3    Calderwood, S.B.4
  • 5
    • 0031015444 scopus 로고    scopus 로고
    • A branch in the ToxR regulatory cascade of Vibrio cholerae revealed by characterization of toxT mutant strains
    • Champion, G.A., Neely, M.N., Brennan, M.A., and DiRita, V.J. (1997) A branch in the ToxR regulatory cascade of Vibrio cholerae revealed by characterization of toxT mutant strains. Mol Microbiol 23: 323-331.
    • (1997) Mol Microbiol , vol.23 , pp. 323-331
    • Champion, G.A.1    Neely, M.N.2    Brennan, M.A.3    DiRita, V.J.4
  • 6
    • 0026519517 scopus 로고
    • Co-ordinate expression of virulence genes by ToxR in Vibrio cholerae
    • DiRita, V.J. (1992) Co-ordinate expression of virulence genes by ToxR in Vibrio cholerae. Mol Microbiol 6: 451-458.
    • (1992) Mol Microbiol , vol.6 , pp. 451-458
    • DiRita, V.J.1
  • 7
    • 0026098804 scopus 로고
    • Periplasmic interaction between two membrane regulatory proteins, ToxR and ToxS, results in signal transduction and transcriptional activation
    • DiRita, V.J., and Mekalanos, J.J. (1991) Periplasmic interaction between two membrane regulatory proteins, ToxR and ToxS, results in signal transduction and transcriptional activation. Cell 64: 29-37.
    • (1991) Cell , vol.64 , pp. 29-37
    • DiRita, V.J.1    Mekalanos, J.J.2
  • 9
    • 0029848941 scopus 로고    scopus 로고
    • Differential expression of the ToxR regulon in classical and El Tor biotypes of Vibrio cholerae is due to biotype-specific control over toxT expression
    • DiRita, V.J., Neely, M., Taylor, R.K., and Bruss, P.M. (1996) Differential expression of the ToxR regulon in classical and El Tor biotypes of Vibrio cholerae is due to biotype-specific control over toxT expression. Proc Natl Acad Sci USA 93: 7991-7995.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7991-7995
    • DiRita, V.J.1    Neely, M.2    Taylor, R.K.3    Bruss, P.M.4
  • 10
    • 0025639196 scopus 로고
    • Transcriptional regulation by iron of a Vibrio cholerae virulence gene and homology of the gene to Escherichia coli fur system
    • Goldberg, M.B., Boyko, S.A., and Calderwood, S.B. (1990a) Transcriptional regulation by iron of a Vibrio cholerae virulence gene and homology of the gene to Escherichia coli Fur system. J Bacteriol 172: 6863-6870.
    • (1990) J Bacteriol , vol.172 , pp. 6863-6870
    • Goldberg, M.B.1    Boyko, S.A.2    Calderwood, S.B.3
  • 11
    • 0025068709 scopus 로고
    • Identification of an iron-regulated virulence determinant in Vibrio cholerae, using TnphoA mutagenesis
    • Goldberg, M.B., DiRita, V.J., and Calderwood, S.B. (1990b) Identification of an iron-regulated virulence determinant in Vibrio cholerae, using TnphoA mutagenesis. Infect Immun 58: 55-60.
    • (1990) Infect Immun , vol.58 , pp. 55-60
    • Goldberg, M.B.1    DiRita, V.J.2    Calderwood, S.B.3
  • 12
    • 0026099665 scopus 로고
    • Positive transcriptional regulation of an iron-regulated virulence gene in Vibrio cholerae
    • Goldberg, M.B., Boyko, S.A., and Calderwood, S.B. (1991) Positive transcriptional regulation of an iron-regulated virulence gene in Vibrio cholerae. Proc Natl Acad Sci USA 88: 1125-1129.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 1125-1129
    • Goldberg, M.B.1    Boyko, S.A.2    Calderwood, S.B.3
  • 13
    • 8944247272 scopus 로고    scopus 로고
    • Capsule phase variation in Neisseria meningitidis serogroup B by slipped-strand mispairing in the polysialyltransferase gene (siaD): Correlation with bacterial invasion and the outbreak of meningococcal disease
    • Hammerschmidt, S., Muller, A., Sillmann, H., Muhlenhoff, M., Borrow, R., Fox, A., van Putten, J., Zollinger, W.D., Gerardy-Schahn, R., and Frosch, M. (1996) Capsule phase variation in Neisseria meningitidis serogroup B by slipped-strand mispairing in the polysialyltransferase gene (siaD): correlation with bacterial invasion and the outbreak of meningococcal disease. Mol Microbiol 20: 1211-1220.
    • (1996) Mol Microbiol , vol.20 , pp. 1211-1220
    • Hammerschmidt, S.1    Muller, A.2    Sillmann, H.3    Muhlenhoff, M.4    Borrow, R.5    Fox, A.6    Van Putten, J.7    Zollinger, W.D.8    Gerardy-Schahn, R.9    Frosch, M.10
  • 14
    • 0020959710 scopus 로고
    • Studies of transformation of Escherichia coli with plasmids
    • Hanahan, D. (1983) Studies of transformation of Escherichia coli with plasmids. J Mol Biol 166: 557-580.
    • (1983) J Mol Biol , vol.166 , pp. 557-580
    • Hanahan, D.1
  • 15
    • 0023736046 scopus 로고
    • Toxin, toxin-regulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans
    • Herrington, D.A., Hall, R.H., Losonsky, G., Mekalanos, J.J., Taylor, R.K., and Levine, M.M. (1988) Toxin, toxin-regulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans. J Exp Med 168: 1487-1492.
    • (1988) J Exp Med , vol.168 , pp. 1487-1492
    • Herrington, D.A.1    Hall, R.H.2    Losonsky, G.3    Mekalanos, J.J.4    Taylor, R.K.5    Levine, M.M.6
  • 16
    • 0028027746 scopus 로고
    • Transcriptional control of toxT, a regulatory gene in the ToxR regulon of Vibrio cholerae
    • Higgins, D.E., and DiRita, V.J. (1994) Transcriptional control of toxT, a regulatory gene in the ToxR regulon of Vibrio cholerae. Mol Microbiol 14: 17-29.
    • (1994) Mol Microbiol , vol.14 , pp. 17-29
    • Higgins, D.E.1    DiRita, V.J.2
  • 17
    • 0026663115 scopus 로고
    • The virulence gene activator ToxT from Vibrio cholerae is a member of the AraC family of transcriptional activators
    • Higgins, D.E., Nazareno, E., and DiRita, V.J. (1992) The virulence gene activator ToxT from Vibrio cholerae is a member of the AraC family of transcriptional activators. J Bacteriol 174: 6974-6980.
    • (1992) J Bacteriol , vol.174 , pp. 6974-6980
    • Higgins, D.E.1    Nazareno, E.2    DiRita, V.J.3
  • 18
    • 0015714290 scopus 로고
    • Comparison of the tissue receptors for Vibrio cholerae and Escherichia coli enterotoxins by means of gangliosides and natural toxoid
    • Holmgren, J. (1973) Comparison of the tissue receptors for Vibrio cholerae and Escherichia coli enterotoxins by means of gangliosides and natural toxoid. Infect Immun 8: 851-859.
    • (1973) Infect Immun , vol.8 , pp. 851-859
    • Holmgren, J.1
  • 19
    • 0023131780 scopus 로고
    • Comparative study of Vibrio cholerae non-O1 protease and soluble hemagglutinin with those of Vibrio cholerae O1
    • Honda, T., Booth, B.A., Boesman-Finkelstein, M., and Finkelstein, R.A. (1987) Comparative study of Vibrio cholerae non-O1 protease and soluble hemagglutinin with those of Vibrio cholerae O1. Infect Immun 55: 451-454.
    • (1987) Infect Immun , vol.55 , pp. 451-454
    • Honda, T.1    Booth, B.A.2    Boesman-Finkelstein, M.3    Finkelstein, R.A.4
  • 20
    • 0023992804 scopus 로고
    • Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I
    • Hovde, C.J., Calderwood, S.B., Mekalanos, J.J., and Collier, R.J. (1988) Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I. Proc Natl Acad Sci USA 85: 2568-2572.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2568-2572
    • Hovde, C.J.1    Calderwood, S.B.2    Mekalanos, J.J.3    Collier, R.J.4
  • 21
    • 0028948017 scopus 로고
    • MyfF, an element of the network regulating the synthesis of fibrillae in Yersinia enterocolitica
    • Iriarle, M., and Cornelis, G.R. (1995) MyfF, an element of the network regulating the synthesis of fibrillae in Yersinia enterocolitica. J Bacteriol 177: 738-744.
    • (1995) J Bacteriol , vol.177 , pp. 738-744
    • Iriarle, M.1    Cornelis, G.R.2
  • 22
    • 0027467127 scopus 로고
    • Biogenesis and regulation of the Vibrio cholerae toxin-coregulated pilus: Analogies to other virulence factor secretory systems
    • Kaufman, M., Shaw, C., Jones, I., and Taylor, R. (1993) Biogenesis and regulation of the Vibrio cholerae toxin-coregulated pilus: analogies to other virulence factor secretory systems. Gene 126: 43-49.
    • (1993) Gene , vol.126 , pp. 43-49
    • Kaufman, M.1    Shaw, C.2    Jones, I.3    Taylor, R.4
  • 23
    • 0021021637 scopus 로고
    • Cholera toxin genes: Nucleotide sequence, deletion analysis and vaccine development
    • Mekalanos, J.J., Swartz, D.J., Pearson, G.D.N., Harford, N., Groyne, F., and deWilde, M. (1983) Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development. Nature 306: 551-557.
    • (1983) Nature , vol.306 , pp. 551-557
    • Mekalanos, J.J.1    Swartz, D.J.2    Pearson, G.D.N.3    Harford, N.4    Groyne, F.5    DeWilde, M.6
  • 24
  • 25
    • 0542390231 scopus 로고
    • Synthesis of cholera toxin is positively regulated at the transcriptional level by ToxR
    • Miller, V.L., and Mekalanos, J.J. (1984) Synthesis of cholera toxin is positively regulated at the transcriptional level by ToxR. Proc Natl Acad Sci USA 81: 3471-3475.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 3471-3475
    • Miller, V.L.1    Mekalanos, J.J.2
  • 26
    • 0023892552 scopus 로고
    • A novel suicide vector and its use in construction of insertion mutations; osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR
    • Miller, V.L., and Mekalanos, J.J. (1988) A novel suicide vector and its use in construction of insertion mutations; osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR. J Bacteriol 170: 2575-2583.
    • (1988) J Bacteriol , vol.170 , pp. 2575-2583
    • Miller, V.L.1    Mekalanos, J.J.2
  • 27
    • 0023667819 scopus 로고
    • Cholera toxin transcriptional activator ToxR is a transmembrane DNA binding protein
    • Miller, V.L., Taylor, R.K., and Mekalanos, J.J. (1987) Cholera toxin transcriptional activator ToxR is a transmembrane DNA binding protein. Cell 48: 271-279.
    • (1987) Cell , vol.48 , pp. 271-279
    • Miller, V.L.1    Taylor, R.K.2    Mekalanos, J.J.3
  • 28
    • 0024603180 scopus 로고
    • Identification of toxS, a regulatory gene whose product enhances toxR-mediated activation of the cholera toxin promoter
    • Miller, V.L., DiRita, V.J., and Mekalanos, J.J. (1989) Identification of toxS, a regulatory gene whose product enhances toxR-mediated activation of the cholera toxin promoter. J Bacteriol 171: 1288-1293.
    • (1989) J Bacteriol , vol.171 , pp. 1288-1293
    • Miller, V.L.1    DiRita, V.J.2    Mekalanos, J.J.3
  • 29
    • 0024536996 scopus 로고
    • Phase variation of gonococcal protein II: Regulation of gene expression by slipped-strand mispairing of a repetitive DNA sequence
    • Murphy, G.L., Connell, T.D., Barritt, D.S., Koomey, M., and Cannon, J.G. (1989) Phase variation of gonococcal protein II: regulation of gene expression by slipped-strand mispairing of a repetitive DNA sequence. Cell 56: 539-547.
    • (1989) Cell , vol.56 , pp. 539-547
    • Murphy, G.L.1    Connell, T.D.2    Barritt, D.S.3    Koomey, M.4    Cannon, J.G.5
  • 30
    • 0026716001 scopus 로고
    • Homology of TcpN, a putative regulatory protein of Vibrio cholerae, to the AraC family of transcriptional activators
    • Ogierman, M.A., and Manning, P.A. (1992) Homology of TcpN, a putative regulatory protein of Vibrio cholerae, to the AraC family of transcriptional activators. Gene 116: 93-97.
    • (1992) Gene , vol.116 , pp. 93-97
    • Ogierman, M.A.1    Manning, P.A.2
  • 31
    • 0027520986 scopus 로고
    • Genetic organization and sequence of the promoter-distal region of the tcp gene cluster of Vibrio cholerae
    • Ogierman, M.A., Zabihi, S., Mourtzois, L., and Manning, P.A. (1993) Genetic organization and sequence of the promoter-distal region of the tcp gene cluster of Vibrio cholerae. Gene 126: 51-60.
    • (1993) Gene , vol.126 , pp. 51-60
    • Ogierman, M.A.1    Zabihi, S.2    Mourtzois, L.3    Manning, P.A.4
  • 32
    • 0029875233 scopus 로고    scopus 로고
    • Comparison of the promoter proximal regions of the toxin-co-regulated tcp gene cluster in classical and El Tor strains of Vibrio cholerae O1
    • Ogierman, M.A., Voss, E., Meaney, C., Faast, R., Attridge, S.R., and Manning, P.A. (1996) Comparison of the promoter proximal regions of the toxin-co-regulated tcp gene cluster in classical and El Tor strains of Vibrio cholerae O1. Gene 170: 9-16.
    • (1996) Gene , vol.170 , pp. 9-16
    • Ogierman, M.A.1    Voss, E.2    Meaney, C.3    Faast, R.4    Attridge, S.R.5    Manning, P.A.6
  • 34
    • 0027506049 scopus 로고
    • A protein required for secretion of cholera toxin through the outer membrane of Vibrio cholerae
    • Sandvist, M., Morales, V., and Bagdasarian, M. (1993) A protein required for secretion of cholera toxin through the outer membrane of Vibrio cholerae. Gene 123: 81-86.
    • (1993) Gene , vol.123 , pp. 81-86
    • Sandvist, M.1    Morales, V.2    Bagdasarian, M.3
  • 35
    • 0025062014 scopus 로고
    • Vibrio cholerae O395 tcpA pilin gene sequence and comparison of predicted protein structural features to those of type 4 pilins
    • Shaw, C.E., and Taylor, R.K. (1990) Vibrio cholerae O395 tcpA pilin gene sequence and comparison of predicted protein structural features to those of type 4 pilins. Infect Immun 58: 3042-3049.
    • (1990) Infect Immun , vol.58 , pp. 3042-3049
    • Shaw, C.E.1    Taylor, R.K.2
  • 36
    • 0013517491 scopus 로고
    • Genetic studies of Vibrio cholerae TCP pilus biogenesis
    • Sack, R.B., and Zinnaka, Y. (eds). Tokyo, Japan: KTK Scientific
    • Shaw, C.E., Peterson, K.M., Mekalanos, J.J., and Taylor, R.K. (1990) Genetic studies of Vibrio cholerae TCP pilus biogenesis. In: Advances in Research on Cholera and Related Diarrheas. Sack, R.B., and Zinnaka, Y. (eds). Tokyo, Japan: KTK Scientific 7: 51-58.
    • (1990) Advances in Research on Cholera and Related Diarrheas , vol.7 , pp. 51-58
    • Shaw, C.E.1    Peterson, K.M.2    Mekalanos, J.J.3    Taylor, R.K.4
  • 37
    • 0031023354 scopus 로고    scopus 로고
    • Cyclic AMP and its receptor protein negatively regulate the coordinate expression of cholera toxin and toxin-coregulated pilus in Vibrio cholerae
    • Skorupski, K., and Taylor, R.K. (1997) Cyclic AMP and its receptor protein negatively regulate the coordinate expression of cholera toxin and toxin-coregulated pilus in Vibrio cholerae. Proc Natl Acad Sci USA 94: 265-270.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 265-270
    • Skorupski, K.1    Taylor, R.K.2
  • 38
    • 0023506006 scopus 로고
    • Molecular characterization of cloned avirulence genes from race O and race 1 of Pseudomonas syringae pv. glycinea
    • Staskawicz, B.D., Dahlbeck, D., Keen, N., and Napoli, C. (1987) Molecular characterization of cloned avirulence genes from race O and race 1 of Pseudomonas syringae pv. glycinea. J Bacteriol 169: 5789-5794.
    • (1987) J Bacteriol , vol.169 , pp. 5789-5794
    • Staskawicz, B.D.1    Dahlbeck, D.2    Keen, N.3    Napoli, C.4
  • 39
    • 0024539059 scopus 로고
    • Phase variation in Bordetella pertussis by frameshift mutation in a gene for a novel two-component system
    • Stibitz, S., Aaronson, W., Monack, D., and Falkow, S. (1989) Phase variation in Bordetella pertussis by frameshift mutation in a gene for a novel two-component system. Nature 338: 266-269.
    • (1989) Nature , vol.338 , pp. 266-269
    • Stibitz, S.1    Aaronson, W.2    Monack, D.3    Falkow, S.4
  • 40
    • 0020787415 scopus 로고
    • An optimized freeze-squeeze method for recovery of DNA fragments
    • Tautz, D., and Renz, M. (1983) An optimized freeze-squeeze method for recovery of DNA fragments. Anal Biochem 132: 14-19.
    • (1983) Anal Biochem , vol.132 , pp. 14-19
    • Tautz, D.1    Renz, M.2
  • 42
    • 0039391898 scopus 로고
    • Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin
    • Taylor, R.K., Miller, V.L., Furlong, D.B., and Mekalanos, J.J. (1987) Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin. Proc Natl Acad Sci USA 84: 2833-2837.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2833-2837
    • Taylor, R.K.1    Miller, V.L.2    Furlong, D.B.3    Mekalanos, J.J.4
  • 43
    • 0030032275 scopus 로고    scopus 로고
    • Variation of gonococcal lipooligosaccharide structure is due to alterations in poly G tracts in lgt genes encoding glycosyl transferases
    • Yang, Q., and Gotschlich, E.C. (1996) Variation of gonococcal lipooligosaccharide structure is due to alterations in poly G tracts in lgt genes encoding glycosyl transferases. J Exp Med 183: 323-327.
    • (1996) J Exp Med , vol.183 , pp. 323-327
    • Yang, Q.1    Gotschlich, E.C.2


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