Induction of micronuclei in V79 cells after combined treatments with heterocyclic aromatic amines

Food and Chemical Toxicology

Volumn 40, Issue 10, 2002, Pages 1463-1467

  Perez, C ^a   Lopez De Cerain, A ^a   Bello, J ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

HAs; Heterocylic aromatic amines; IQ; Iqx; Micronuclei; PhIP; V79 cells

Indexed keywords

2 AMINO 3 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; 2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOXALINE; ANEUGEN; CLASTOGEN; CYTOCHALASIN B; HETEROCYCLIC AMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIUM MUTANT; CELL STRAIN V 79; CONTROLLED STUDY; COOKING; CYTOKINESIS; EUKARYOTE; IN VITRO STUDY; METABOLIC ACTIVATION; MICRONUCLEUS; MUTAGENICITY; NONHUMAN;

CELL LINE; CELL NUCLEUS; CYTOCHALASIN B; DRUG INTERACTIONS; FOOD ANALYSIS; HEAT; IMIDAZOLES; MUTAGENS; QUINOLINES; QUINOXALINES;

EUKARYOTA;

EID: 0036775604     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(02)00082-0     Document Type: Article

References (32)

1. Augustsson K., Skog K., Jägerstad M., Steineck G. Assessment of the human exposure of heterocyclic amines. Carcinogenesis. 18:1997;1931-1935.
2. Augustsson K., Lindblad J., Övervik E., Steineck G. A population-based dietary inventory of cooked meat and assessment of the daily intake of food mutagens. Food Additives and Contaminants. 16:1999;215-225.
3. Breneman J.W., Briner J.F., Ramsey M.J., Director A., Tucker J.D. Cytogenetic results from a chronic feeding study of MeIQx in mice. Food and Chemical Toxicology. 34:1996;717-724.
4. Brooks R.A., Gooderham N.J., Zhao K., Edwards R.J., Howard L.A., Boobis A.R., Winton D.J. 2-Amino-1-methyl-6-phenyl-imidazo(4, 5-b)pyridine is a potent mutagen in the mouse small intestine. Cancer Research. 54:1994;1665-1671.
5. Commoner B., Vithayathil A.J., Dolara P., Nair S., Madyastha P., Cuca G.C. Formation of mutagens in beef and beef extract during cooking. Science. 201:1978;913-916.
6. Countryman P.I., Heddle J.A. The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes. Mutation Research. 41:1976;321-332.
7. Director A.E., Nath J., Ramsey M.J., Swiger R.R., Tucker J.D. Cytogenetic analysis of mice chronically fed the food mutagen 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine. Mutation Research. 359:1996;53-61.
8. Felton J.S., Healy S., Stuermer D., Berry C., Timourian H., Hatch F.T. Mutagens from the cooking of food. I. Improved extraction and characterization of mutagenic fractions from cooked ground beef. Mutation Research. 88:1991;33-44.
9. Felton J.S., Knize M.G., Wood C., Wuebbles B.J., Healy S.K., Stuermer D.H., Bjeldanes L.F., Kimble B.J., Hatch F.T. Isolation and characterization of new mutagens from fried ground beef. Carcinogenesis. 5:1984;95-102.
10. Felton J.S., Knize M.G., Dolbeare F.A., Wu R. Mutagenic activity of heterocyclic amines in cooked foods. Environmental Health Perspectives. 102:1994;201-204.
11. Gocke E., Eckhardt K., King M.T., Wild D. Mutagenicity study of fried sausages in Salmonella, Drosophila and mammalian cells in vitro and in vivo. Mutation Research. 101:1982;293-304.
12. Hargraves W.A., Pariza M.W. Purification and mass spectral characterization of bacterial mutagens from commercial beef extract. Cancer Research. 43:1983;1467-1472.
13. Heddle J.A., Knize M.G., Dawod D., Zhang X.B. A test mutagenicity of cooked meats in vivo. Mutagenesis. 16:2001;103-107.
14. Holme J.A., Hongslo J.K., Soderlund E., Brunborg G., Christensen T., Alexander J., Dybing E. Comparative genotoxic effects of, I. Q. and MeIQ in Salmonella typhimurium and cultured mammalian cells. Mutation Research. 187:1987;181-190.
15. Kalweit S., Utesch D., von der, Hude W., Madle S. Chemically induced micronucleus formation in V79 cells-comparison of three different test approaches. Mutation Research. 439:1999;183-190.
16. Keating G.A., Bogen K.T. Methods for estimating heterocyclic amine concentrations in cooked meats in the US diet. Food and Chemical Toxicology. 39:2001;29-43.
17. Knasmüller S., Schwab C.E., Land S.J., Wang C.Y., Sanyal R., Kundi M., Parzefall W., Darroudi F. Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells. Mutagenesis. 14:1999;533-539.
18. Layton D.W., Bogen K.T., Knize M.G., Hatch F.T., Johnson V.M., Felton J.S. Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research. Carcinogenesis. 16:1995;39-52.
19. Malfatti M.A., Shen M.G., Wu W., Turteltaub W., Felton J.S. A correlation of Salmonella mutagenicity with DNA adducts induced by the cooked-food mutagen 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine. Mutagenesis. 10:1995;425-443.
20. Maron M., Ames B.N. Revised methods for the Salmonella mutagenicity test. Mutation Research. 113:1983;173-215.
21. Minissi S., Gustavino B., Degrassi F., Tanzarella C., Rizzoni M. Effect of cytochalasin B on induction of chromosome missegregation by colchicine at low concentrations in human lymphocytes. Mutagenesis. 14:1999;43-49.
22. Natarajan A.T., Darroudi F. Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens. Mutagenesis. 6:1991;399-403.
23. Pariza M.W., Ashoor S.H., Chu F.S., Lund D.B. Effects of temperature and time on mutagen formation in pan-fried hamburger. Cancer Letters. 7:1979;63-69.
24. Ramírez M.J., Surrallés J., Puerto S., Creus A., Marcos R. Aneugenic activity in human cultured lymphocytes. An overall study with colchicine using the micronucleus assay and fluorescence in situ hybridization techniques. Mutagenesis. 12:1997;405-410.
25. Ramsey M.J., Nagao M., Inoue R., Fujita H., Matsushima T., Tucker J.D. Chromosome aberrations induced in mice by chronic feeding of 2-amino-3, 4-dimethylimidazo(4, 5-f)quinoline (MeIQ. Food and Chemical Toxicology. 36:1998;467-474.
26. Sinha R., Rothman N. Exposure assessment of heterocyclic amines (HCAs) in epidemiologic studies. Mutation Research. 376:1997;195-202.
27. Skog K. Cooking procedures and food mutagens: a literature review. Food and Chemical Toxicology. 31:1993;655-675.
28. Spingarn N.E., Weisburger J.H. Formation of mutagens in cooked foods. I. Beef Cancer Letters. 7:1979;259-264.
29. Takayama S., Nakatsuru Y., Sato S. Carcinogenic effect of the simultaneous administration of five heterocyclic amines to F344 rats. Japanese Journal of Cancer Research. 78:1987;1068-1072.
30. Tohda H., Oikawa A., Kawachi T., Sugimura T. Induction of sister-chromatid exchanges by mutagens from amino acid and protein pyrolysates. Mutation Research. 77:1980;65-69.
31. Thompson L.H., Carrano A.V., Salazar E., Felton J.S., Hatch F.T. Comparative genotoxic effects of the cooked-food-related mutagens Trp-P-2 and IQ in bacteria and cultured mammalian cells. Mutation Research. 117:1983;243-257.
32. Wakabayashi K., Nagao M., Esumi H., Sugimura T. Food-derived mutagens and carcinogens. Cancer Research. 52:1992;2092-2098.