Exposure assessment of heterocyclic amines (HCAs) in epidemiologic studies

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 376, Issue 1-2, 1997, Pages 195-202

  Sinha, Rashmi ^a   Rothman, Nathaniel ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Biomarker; Cancer; Cooking; Epidemiology; Genetic susceptibility; Heterocyclic amine; Meat; Questionnaire

Indexed keywords

HETEROCYCLIC AMINE;

ARTICLE; CANCER; CARCINOGENICITY; COLON CANCER; COOKING; DATA BASE; EPIDEMIOLOGY; FOOD; GENETIC SUSCEPTIBILITY; HUMAN; MEAT; PRIORITY JOURNAL; QUESTIONNAIRE;

AMINES; ARYLAMINE N-ACETYLTRANSFERASE; BIOTRANSFORMATION; CARCINOGENS; COOKERY; CYTOCHROME P-450 CYP1A2; DIET; ENVIRONMENTAL EXPOSURE; EPIDEMIOLOGY; HEAT; HETEROCYCLIC COMPOUNDS; HUMANS; MEAT;

GALLUS GALLUS;

EID: 0031008972     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(97)00043-2     Document Type: Article

References (34)

1. Adamson, R.H. (1990) Mutagens and carcinogens formed during cooking of food and methods to minimize their formation, in: V.T. DeVita, S. Hellman and S.A. Rosenberg (Eds.), Cancer Prevention, J.B. Lippincott Company, Philadelphia, pp. 1-7.
2. Adamson, R.H., E.G. Snyderwine, U.P. Thorgeirsson, H.A. Schut, R.J. Turesky, S.S. Thorgeirsson, S. Takayama and T. Sugimura (1990) Metabolic processing and carcinogenicity of heterocyclic amines in nonhuman primates, Princess Takamatsu. Symp., 21, 289-301.
3. Adamson, R.H., E.G. Snyderwine, U.P. Thorgeirsson, H.A.J. Schut, R.J. Turesky, S.S. Thorgeirsson, S. Takayama and T. Sugimura (1991) Metabolic processing and carcinogenicity of heterocyclic amines in non-human primates, in: L. Ernster, H. Esumi and Y. Fujii (Eds.), Xenobiotics and Cancer, Japan Sci. Soc. Press, Tokyo, pp. 289-301.
4. Boobis, A.R., A.M. Lynch, S. Murray, R. Torre, A. Solans, M. Farre, J. Segura, N.J. Gooderham and D.S. Davies (1994) CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans, Cancer Res., 54, 89-94.
5. Butler, M.A., N.P. Lang, J.F. Young, N.B. Caporaso, P. Vineis, R.B. Hayes, C.H. Teitel, J.P. Massengill, M.F. Lawsen and F.F. Kadlubar (1992) Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites, Parmacogenetics, 2, 116-127.
6. Degawa, M., S. Tanimura, T. Agatsuma and Y. Hasimoto (1989) Hepatocarcinogenic heterocyclic aromatic amines that induce cytochrome P-488 isoenzymes, mainly cytochrome P-448H (P-450IA2), responsible for mutagenic activation of the carcinogens in rat liver, Carcinogenesis, 10, 1119-1122.
7. Felton, J.S. and M.G. Knize (1990) New mutagens from cooked food, Prog. Clin. Biol. Res., 347, 19-38.
8. Felton, J.S. and M.G. Knize (1991) Occurrence, identification, and bacterial mutagenicity of heterocyclic amines in cooked food, Mutat. Res., 205-217.
9. Gerhardsson De Verdier, M., U. Hagman, R.K. Peters, G. Steineck and E. Overvik (1991) Meat, cooking methods and colorectal cancer: A case-referent study in Stockholm, Int. J. Cancer., 49, 520-525.
10. Ghoshal, A., K.H. Preisegger, S. Takayama, S.S. Thorgeirsson and E.G. Snyderwine (1994) Induction of mammary tumors in female Sprague-Dawley rats by the food-derived carcinogen2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and effect of dietary fat, Carcinogenesis, 15, 2429-2433.
11. Gross, G.A. and A. Gruter (1992) Quantitation of mutagenic/carcinogenic heterocyclic amines in food products, J. of Chromatography, 592, 271-278.
12. Hill, A.B. (1965) Environment and disease: Association or causation?, Proc. R. Soc. Med., 58, 295-300.
13. Ito, N., R. Hasegawa, M. Sano, S. Tamano, H. Esumi, S. Takayama and T. Sugimura (1991) A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), Carcinogenesis, 12, 1503-1506.
14. Kaaks, R. (1996) Biochemical markers as an additional measurement in studies on the accuracy of dietary questionnaire measurements, Am. J. Clin. Nutr., in press.
15. Knekt, P., G. Steineck, R. Jarvinen, T. Hakulinen and A. Aromaa (1994) Intake of fried meat and risk of cancer: a follow-up study in Finland, Int. J. Cancer, 59, 756-760.
16. Knize, M.G., R. Sinha, N. Rothman, E.D. Brown, C.P. Salmon, O.A. Levander and J.S. Felton (1995) Fast-food meat products have relatively low heterocyclic amine content, Food. Chem. Toxicol., 33, 545-551.
17. Knize, M.G., R. Sinha, C.P. Salmon, S.S. Metha, K.P. Dewhirst and J.S. Felton (1996) Formation of heterocyclic amine mutagens/carcinogens during cooking of muscle meat, J. Muscle Food, 7, 271-290.
18. Layton, D.W., K.T. Bogen, M.G. Knize, F.T. Hatch, V.M. Johnson and J.S. Felton (1995) Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research, Carcinogenesis, 16, 39-52.
19. Lynch, A.M., M.G. Knize, A.R. Boobis, N.J. Gooderham, D.S. Davies and S. Murray (1992) Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef, Cancer Res., 52, 6216-6223.
20. National Center for Health Statistics, Office of Health Research, Statistics and Technology. (1981) Vital Health and Statistics, US GPO, Series 1, no. 15, Washington, DC.
21. Ohgaki, H., H. Hasegawa, T. Kato, M. Suenaga, M. Ubukata, S. Sato, S. Takayama and T. Sugimura (1986) Carcinogenicity in mice and rats of heterocyclic amines in cooked foods, Environ. Health Perspect., 67, 129-134.
22. Schiffman, M.H., R. Van Tassell and A.W. Andrew (1990) Epidemiologic studies of fecal mutagenicity, cooked meat ingestion, and risk of colorectal cancer, Mutation and the Environment, 205-214.
23. Sinha, R., N. Rothman, E. Brown, S. Mark, R. Hoover, N. Caporaso, O. Levander, M. Knize, N. Lang and F. Kadlubar (1994) Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome P4501A2 activity in humans, Cancer Res, 54, 6154-6159.
24. Sinha, R., N. Rothman, S.D. Mark, S. Murray, E.D. Brown, O.A. Levander, D.S. Davies, N.P. Lang, F.F. Kadlubar and R.N. Hoover (1995) Lower levels of urinary 2-amino-3,8-dimethyl-imidazo[4,5-f]-quinoxaline (MeIQx) in humans with higher CYP1A2 activity, Carcinogenesis, 16, 2859-2861.
25. Skog, K. (1993) Cooking procedures and food mutagens: a literature review, Food Chem. Toxicol., 31, 655-675.
26. Smucker, R., G. Block, L. Coyle, A. Harvin and L. Kessler (1989) A dietary and risk factor questionnaire and analysis system for personal computers, Am. J. Epidemiol., 129, 445-449.
27. Steineck, G., M. Gerhardsson De Verdier and E. Overvik (1993) The epidemiological evidence concerning intake of mutagenic activity from the fried surface and the risk of cancer cannot justify preventive measures, Eur. J. Cancer Prev., 2, 293-300.
28. Sugimura, T., S. Sato and K. Wakabayashi (1988) Mutagens/carcinogens in pyrolysate of amino acids and proteins and in cooked foods: Heterocyclic aromatic amines, in: Y.T. Woo, D.Y. Lai, J.C. Arcos and M.F. Argue (Eds.), Chemical Induction of Cancer, Structural Bases and Biological Mechanisms, Academic Press Inc, New York, pp. 681-710.
29. Thompson, F.E. and T. Byers (1994) Dietary assessment resource manual, J. Nutr., 124, 2245S-2317S.
30. Turesky, R.J., N.P. Lang, M.A. Butler, C.H. Teitel and F.F. Kadlubar (1991) Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon, Carcinogenesis, 12, 1839-1845.
31. United States Department of Agriculture, (1986) Nationwide Food Consumption Survey, Continuing Survey of Food Intakes by Individuals. Women 19-50 Years and their Children 1-5 Years, 4 Days, NFCS, CSFII Report No. 86-3, Hyattsville, MD.
32. United States Department of Agriculture, Human Nutrition Information Service. (1988) Composition of foods: raw, processed, prepared. Agriculture Handbook nos. 8-1 through 8-22, US Government Printing Office, Washington, DC.
33. Wakabayashi, K., H. Ushiyama, M. Takahashi, H. Nukaya, S.B. Kim, M. Hirose, M. Ochiai, T. Sugimura and M. Nagao (1993) Exposure to heterocyclic amines, Environ. Health Perspect., 99, 129-134.
34. Weisburger, J.H., A. Rivenson, G.C. Hard, E. Zang, M. Nagao and T. Sugimura (1994) Role of fat and calcium in cancer causation by food mutagens, heterocyclic amines, Proc. Soc. Exp. Biol. Med, 205, 347-352.