Recombinant antibody Fab against the hypervariable region 1 of hepatitis C virus blocks the virus adsorption to susceptible cells in vitro

Antiviral Research

Volumn 56, Issue 1, 2002, Pages 51-59

  Zhou, Yi Hua ^a   Takekoshi, Masataka ^b   Maeda, Fumiko ^b   Ihara, Seiji ^b   Esumi, Mariko ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Antiviral effect; Hepatitis C virus; Hypervariable region 1; Immunoglobulin; Recombinant Fab

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; NICKEL COMPLEX; RECOMBINANT ANTIBODY;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA PURIFICATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; HEPATITIS C VIRUS; HYBRIDOMA CELL CULTURE; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOTHERAPY; IN VITRO STUDY; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; VIRUS ADSORPTION; VIRUS NEUTRALIZATION;

ADSORPTION; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; HEPACIVIRUS; HEPATITIS C ANTIBODIES; IMMUNOGLOBULIN FAB FRAGMENTS; MICE; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS; RECOMBINANT PROTEINS; VIRAL PROTEINS;

ESCHERICHIA COLI; HEPATITIS C VIRUS;

EID: 0036775245     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(02)00092-X     Document Type: Article

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