Experimental vaccine activities of recombinant E1 and E2 glycoproteins and hypervariable region 1 peptides of hepatitis C virus in chimpanzees

Archives of Virology

Volumn 144, Issue 5, 1999, Pages 973-980

  Esumi, M ^a   Rikihisa, T ^b   Nishimura, S ^b   Goto, J ^c   Mizuno, K ^b   Zhou, Y H ^a   Shikata, T ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Chemo Sero Therapeut Res Institute   (Japan)

^c KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMPANZEE; HEPATITIS C VIRUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODY FORMATION; HEPACIVIRUS; HEPATITIS C; MOLECULAR SEQUENCE DATA; PAN TROGLODYTES; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS; VACCINES, SYNTHETIC; VARIATION (GENETICS); VIRAL ENVELOPE PROTEINS; VIRAL HEPATITIS VACCINES;

EID: 0032985216     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007050050559     Document Type: Article

References (21)

1. Ahmed M, Shikata T, Esumi M (1996) Murine humoral immune response against recombinant structural proteins of hepatitis C virus distinct from those of patients. Microbiol Immunol: 169-176
2. Alter MJ (1997) Epidemiology of hepatitis C. Hepatology 26: 62S-65S
3. Choo Q-L, Kuo G, Ralston R, Weiner A, Chien D, Van Nest G, Han J, Berger K, Thudium K, Kuo C, Kansopon J, McFarkland J, Tabrizi A, Ching K, Moss B, Cummins LB, Houghton M, Muchmore E (1994) Vaccination of chimpanzees against infection by the hepatitis C virus. Proc Natl Acad Sci USA 91: 1294-1298
4. Choo Q-L, Richman KH, Han JH, Berger K, Lee C, Dong C, Gallegos C, Coit D, Medina-Silby A, Barr PJ, Bradley DW, Kuo G, Houghton M (1991) Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci USA 88: 2451-2455
5. Esumi M, Ahmed M, Zhou Y-H, Takahashi H, Shikata T (1998) Murine anti-E2 and antihypervariable region 1 antibodies cross-reactively capture hepatitis C virus. Virology 251: 158-164
6. Esumi M, Shikata T (1994) Hepatitis C virus and liver diseases. Pathol Int 44: 85-95
7. Farci P, Alter HJ, Govindarajan S, Wong DC, Angle R, Lesniewski RR, Mushahwar IK, Desai SM, Miller RH, Ogata N, Purcell RH (1992) Lack of preventive immunity against reinfection with hepatitis C virus. Science 258: 135-140
8. Farci P, Alter HJ, Wong DC, Miller RH, Givindarajan S, Engle R, Shapiro M, Purcell RH (1994) Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization. Proc Natl Acad Sci USA 91: 7792-7796
9. Farci P, Schimoda A, Wong D, Cabezon T, De Gioannis D, Strazzera A, Shimizu Y, Shapiro M, Alter HJ, Purcell RH (1996) Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein. Proc Natl Acad Sci USA 93: 15394-15399
10. Hijikata M, Kato N, Ootsuyama Y, Nakagawa M, Ohkoshi S, Shimotohno K (1991) Hypervariable regions in the putative glycoprotein of hepatitis C virus. Biochem Biophys Res Commun 175: 220-228
11. Kato N, Hijikata M, Ootsuyama Y, Nakagawa M, Ohkoshi S, Sugumura T, Shimotohno K (1990) Molecular cloning of non-A, non-B, hepatitis. Proc Natl Acad Sci USA 87: 9524-9528
12. Mizuno M, Higuchi T, Kanmimatsuse K., Esumi M (1998) Genetic and serological evidence for multiple instances of unrecognized transmission of hepatitis C virus in hemodialysis units. J Clin Microbiol 36: 2926-2931
13. Nishihara T, Nozaki C, Nakatake H, Hoshiko K, Esumi M, Hayashi N, Hino K, Hamada F, Mizuno K, Shikata T (1993) Secretion and purification of hepatitis C virus NS1 glycoprotein produced by recombinant baculovirus-infecled insect cells, Gene 129:207-214
14. Prince AM, Brotman B, Huima T, Pascual D, Jaffery M, Inchauspe G (1992) Immunity in hepatitis C infection. J Infect Dis 165: 438-443
15. Ralston R, Thudium K, Berger K, Kuo C, Gervase B, Hall J, Selby M, Kuo G, Houghton M, Choo Q-L (1993) Characterization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia viruses. J Virol 67: 6753-6761
16. Saito I, Miyamura T, Ohbayashi A, Harada H, Katayama T, Kikuchi S, Watanabe Y, Koi S, Onji M, Ohta Y, Choo Q-L, Houghton M, Kuo G (1990) Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc Natl Acad Sci USA 87: 6547-6549
17. Shimizu YK, Weiner AJ, Rosenblatt J, Wong DC, Shapiro M, Popkin T, Houghton M, Alter HJ, Purcell RH (1990) Early events in hepatitis C virus infection of chimpanzees. Proc Natl Acad Sci USA 87: 6441-6444
18. Sugitani M, Shikata T (1998) Comparison of amino acid sequences in hypervariable region-1 of hepatitis C virus clones between human inocula and the infected chimpanzee sera. Virus Res 56: 177-182
19. Taniguchi S, Okamoto H, Sakamoto M, Kojima M, Tsuda F, Tanaka T, Munekata E, Muchmore EE, Peterson Da, Mishiro S (1993) A structurally flexible and antigenically variable N-terminal domain of the hepatitis C virus E2/NS1 protein; Implication for an escape from antibody. Virology 195: 297-301
20. Weiner AJ, Brauer MJ, Rosenblatt J, Richman KH, Tung J, Crawford K, Bonino F, Saracco G, Choo Q-L, Houghton M, Han JH (1991) Variable and hypervariable domains are found in the regions of HCV corresponding to the Flavivirus envelope and NS1 proteins and the Pestivirus envelope glycoproteins. Virology 180: 842-848
21. Weiner AJ, Geysen HM, Christophersin C, Hall JE, Mason TS, Saracco G, Bonino F, Crawford K, Marion CD, Crawford KA, Brunetto M, Barr PJ, Miyamura T, Mchutchchinson J, Houghton M (1992) Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: Potential role in chronic HCV infections. Proc Natl Acad Sci USA 89: 3468-3472