Human monoclonal anti-HCMV neutralizing antibody from phage display libraries

Journal of Virological Methods

Volumn 74, Issue 1, 1998, Pages 89-98

  Takekoshi, M ^a   Maeda, F ^a   Tachibana, H ^a   Inoko, H ^a   Kato, S ^a   Takakura, I ^a   Kenjyo, T ^a   Hiraga, S ^a   Ogawa, Y ^a   Horiki, T ^a   Ihara, S ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Human cytomegalovirus; Human monoclonal antibody; Neutralizing antibody; Phage display

Indexed keywords

CYTARABINE; DNA FRAGMENT; HUMAN MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY;

ARTICLE; CYTOMEGALOVIRUS INFECTION; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; MOLECULAR CLONING; PHAGE DISPLAY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODIES, VIRAL; BACTERIOPHAGES; CELL LINE; CLONING, MOLECULAR; CYTOMEGALOVIRUS; EPITOPES, B-LYMPHOCYTE; FLUORESCENT ANTIBODY TECHNIQUE; GENES, VIRAL; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS; PEPTIDE LIBRARY; SEQUENCE ANALYSIS;

EID: 0031839459     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-0934(98)00072-X     Document Type: Article

References (28)

1. Ayata, M., Sugano, T., Murayama, T., et al., 1994. Different antibody response to a neutralizing epitope of human cytomegalovirus glycoprotein B among seropositive individuals. J. Med. Virol. 43, 386-392.
2. Barbas, C.F., Bjöling, E., Chiodi, F., et al., 1992. Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro. Proc. Natl. Acad. Sci. USA 89, 9339-9343.
3. Bird, R.E., Hardman, K.D., Jacobson, J.W., et al., 1988. Single-chain antigen-binding proteins. Science 242, 423-426.
4. Boulianne, G.L., Hozumi, N., Schulman, M.J., 1984. Production of functional chimaeric mouse/human antibody. Nature 312, 643-646.
5. Burioni, R., Williamson, A., Sanna, P.P., Bloom, F.E., Burton, D.R., 1994. Recombinant human Fab to glycoprotein D neutralizes infectivity and prevents cell-to-cell transmission of herpes simplex viruses 1 and 2 in vitro. Proc. Natl. Acad. Sci. USA 91, 355-359.
6. Don, R.H., Cox, P.T., Wainwright, B.J., Baker, K., Mattic, J.S., 1991. 'Touchdown' PCR to circumvent spurious priming during gene amplification. Nucleic Acids Res. 19, 4008.
7. Gallant, J.E., Moore, R.D., Richman, D.D., Jeanne, K., Chaisson, R.E., 1992. Incidence and natural history of cytomegalovirus disease in patients with advanced human immunodeficiency virus disease treated with zidovudine. J. Infect. Dis. 166, 1223-1227.
8. Green, L.L., Hardy, M.C., Maynard-Currie, C.E., et al., 1994. Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs. Nat. Genet. 7, 13-21.
9. James, K., Bell, G.T., 1987. Human monoclonal antibody production: current status and future prospects. J. Immunol. Methods 100, 5-40.
10. Joassin, L., Somze, A., Register, M., 1989. Detection by enzyme-linked immunosorbent assay of specific immunoglobulin G isotypes in primary and established cytomegalovirus infections. J. Clin. Microbiol. 27, 139-144.
11. Jones, P.T., Dear, P.H., Foote, J., Neuberger, M.S., Winter, G., 1986. Replacing the complementarity-determining regions in a human antibody with those from a mouse. Nature 321, 522-525.
12. Li, C.R., Greenberg, P.D., Gilbert, M.J., Goodrich, J. M., Riddell, S.R., 1994. Recovery of HLA-restricted cytomegalovirus (CMV)-specific T-cell responses after allogeneic bone marrow transplant: correlation with CMV disease and effect of gancicrovir prophylaxis. Blood 83, 1971-1979.
13. Lonberg, N., Taylor, L.D., Harding, F.A., et al., 1994. Antigen-specific human antibodies from mice comprising four distinct genetic modifications. Nature 368, 856-859.
14. Masuho, Y., Matsumoto, Y., Sugano, T., Fujinaga, S., Minamishima, Y., 1987. Human monoclonal antibodies neutralizing human cytomegalovirus. J. Genet Virol. 68, 1457-1461.
15. McCafferty, J., Griffiths, A.D., Winter, G., Chiswell, D.J., 1990. Phage antibodies: filamentous phage displaying antibody variable domains. Nature 348, 552-554.
16. Mendez, M.J., Green, L.L., Corvalan, J.R.F., et al., 1997. Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice: antigen-specific human antibodies from mice comprising four distinct genetic modifications. Nat. Genet. 15, 146-156.
17. Meyers, J.D., Reed, E.C., Sheep, D.H., et al., 1988. Acyclovir for prevention of cytomegalovirus infection and disease after allogeneic marrow transplantation. New Engl. J. Med. 318, 70-75.
18. Morrison, S.L., Johnson, M.J., Herzenberg, L.A., Oi, V.T., 1984. Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains. Proc. Natl. Acad. Sci. USA 81, 6851-6855.
19. Mullinax, R., Gross, E.A., Amberg, J.R., et al., 1990. Identification of human antibody fragment clones specific for tetanus toxoid in a bacteriophage lambda immunoexpression library. Proc. Natl. Acad. Sci. USA 87, 8095-8099.
20. Ohlin, M., Sundqvist, V.A., Mach, M., Wahren, B., Borrebaeck, C.A.K., 1993. Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies. J. Virol. 67, 703-710.
21. Persson, M.A.A., Caothien, R.H., Burton, D.R., 1991. Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning. Proc. Natl. Acad. Sci. USA 88, 2432-2436.
22. Prentice, H.G., Gluckman, E., Powles, R.L., et al., 1994. Impact of long-term acyclovir on cytomegalovirus infection and survival after allogeneic bone marrow transplantation. Lancet 343, 749-753.
23. Reed, B.C., Bowden, R.A., Dandliker, P.S., Lilleby, K.E., Meyers, J.D., 1988. Treatment of cytomegalovirus pneumonia with ganciclovir and intravenous cytomegalovirus immunoglobulin in patients with bone marrow transplants. Ann. Intern. Med. 109, 783-788.
24. Sanna, P.P., Williamson, R.A., De Logue, A., Bloom, F.E., Burton, D.R., 1995. Directed selection of recombinant human monoclonal antibodies to herpes simplex virus glycoproteins from phage display libraries. Proc.Natl. Acad. Sci. USA 92, 6439-6443.
25. Snydman, D.R., Werner, E.G., Dougherty, N.N., et al., 1993. Cytomegalovirus immune globulin prophylaxis in liver transplantation. Ann. Intern. Med. 119, 984-991.
26. Takekoshi, M., Ihara, S., Tanaka, S., Maeda-Takekoshi, F., Watanabe, Y., 1987. A new human cytomegalovirus isolate has an invertible subsegment within its L component producing eight genome isomers. J. Gen. Virol. 68, 765-776.
27. Urban, M., Britt, W., Mach, M., 1992. The dominant linear neutralizing antibody-binding site of glycoprotein gp86 of human cytomegalovirus is strain specific. J. Virol. 66, 1303-1311.
28. Williamson, R.A., Burioni, R., Sanna, P.P., Partridge, L.J., Barbas, C.F., Burton, D.R., 1993. Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries. Proc. Natl. Acad. Sci. USA 90, 4141-4145.