Agonist-induced GTPγ35S binding mediated by human 5-HT(2C) receptors expressed in human embryonic kidney 293 cells

European Journal of Pharmacology

Volumn 383, Issue 3, 1999, Pages 311-319

  Alberts, Glen L ^a   Pregenzer, Jeffrey F ^a   Im, Wha Bin ^a   Zaworski, Philip G ^b   Gill, Gurnam S ^b  

^a Pharmacia Upjohn 301 Henrietta St   (United States)

^b Cell and Molecular Biology   (United States)

Author keywords

G protein coupling; GTP 35S binding; Human 5 HT(2C) receptor; Intrinsic efficacy; IP3 signal

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; ADENYLATE CYCLASE; ANTIOBESITY AGENT; CLOZAPINE; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE; LYSERGIDE; METERGOLINE; METITEPINE; ORG 37684; PERTUSSIS TOXIN; SEROTONIN; SEROTONIN 2C RECEPTOR; UNCLASSIFIED DRUG; BORDETELLA VIRULENCE FACTOR; CYCLIC AMP; ERGOLINE DERIVATIVE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MESULERGINE; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ARTICLE; BINDING SITE; CELL STRAIN 3T3; CONCENTRATION RESPONSE; EMBRYO; HUMAN; HUMAN CELL; KIDNEY CELL; LIGAND BINDING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CYTOLOGY; DRUG EFFECT; KIDNEY; METABOLISM; PRENATAL DEVELOPMENT;

CYCLIC AMP; ERGOLINES; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; KIDNEY; PERTUSSIS TOXIN; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN ANTAGONISTS; VIRULENCE FACTORS, BORDETELLA;

EID: 0032585889     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00653-6     Document Type: Article

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