Expression and role of roundabout-1 in embryonic Xenopus forebrain

Developmental Dynamics

Volumn 225, Issue 1, 2002, Pages 22-34

  Connor, R M ^a   Key, B ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Axon; Brain; Chemorepulsion; Guidance; Navigation; Neurogenesis

Indexed keywords

GREEN FLUORESCENT PROTEIN; PROTEIN ROBO1; PROTEIN ROUNDABOUT 1; RECEPTOR PROTEIN; RNA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BLASTOMERE; BRAIN DEVELOPMENT; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FOREBRAIN; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEUROEPITHELIUM; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; RNA SYNTHESIS; XENOPUS LAEVIS;

ANIMALS; AXONS; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUMINESCENT PROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; NEURONS; PHYLOGENY; PROSENCEPHALON; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IMMUNOLOGIC; TIME FACTORS; XENOPUS LAEVIS;

MAMMALIA; VERTEBRATA;

EID: 0036729464     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/dvdy.10130     Document Type: Article

References (41)

1. Expression of a novel N-CAM glycoform (NOC-1) on axon tracts in embryonic Xenopus brain
2. Novel guidance cues during neuronal pathfinding in the early scaffold of axon tracts in the rostral brain
3. Chondroitin sulfates modulate axon guidance in embryonic Xenopus brain
4. DCC plays a role in navigation of forebrain axons across the ventral midbrain commissure in embryonic xenopus
5. Expression and putative role of neuropilin-1 in the early scaffold of axon tracts in embryonic Xenopus brain
6. Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the Mammalian forebrain
7. Chimeric axon guidance receptors: The cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion
8. Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor
9. Axon repulsion from the midline of the Drosophila CNS requires slit function
10. Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance
11. Embryonic expression and extracellular secretion of Xenopus slit
12. The N-terminal leucine-rich regions in Slit are sufficient to repel olfactory bulb axons and subventricular zone neurons
13. Conservation and divergence of axon guidance mechanisms
14. Retinal ganglion cell axon guidance in the mouse optic chiasm: Expression and function of robos and slits
15. Silencing the siren. Guidance cue hierarchies at the CNS midline
16. C. elegans slit acts in midline, dorsal-ventral, and anterior-posterior guidance via the SAX-3/Robo receptor
17. Cephalic expression and molecular characterization of Xenopus En-2
18. Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors
19. Dosage-sensitive and complementary functions of roundabout and commissureless control axon crossing of the CNS midline
20. Slit is the midline repellent for the robo receptor in Drosophila
21. Roundabout signalling, cell contact and trophic support confine longitudinal glia and axons in the Drosophila CNS
22. Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs
23. Effects of roundabout on growth cone dynamics, filopodial length, and growth cone morphology at the midline and throughout the neuropile
24. Expression of the vertebrate Slit gene family and their putative receptors, the Robo genes, in the developing murine kidney
25. Slit1 and slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system
26. Crossing the midline: Roles and regulation of Robo receptors
27. Selecting a longitudinal pathway. Robo receptors specify the lateral position of axons in the Drosophila CNS
28. New roundabouts send axons into the Fas lane
29. Attraction versus repulsion: Modular receptors make the difference in axon guidance
30. Mutations affecting growth cone guidance in Drosophila: Genes necessary for guidance toward or away from the midline
31. Short-range and long-range guidance by slit and its Robo receptors. Robo and Robo2 play distinct roles in midline guidance
32. Hierarchical organization of guidance receptors: Silencing of netrin attraction by slit through a Robo/DCC receptor complex
33. The DUTT1 gene, a novel NCAM family member is expressed in developing murine neural tissues and has an unusually broad pattern of expression
34. Commissureless controls growth cone guidance across the CNS midline in Drosophila and encodes a novel membrane protein
35. Expression patterns of slit and robo family members during vertebrate limb development
36. Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching
37. Regulation of cortical dendrite development by slit-robo interactions
38. Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in Xenopus and zebrafish hindbrain
39. The mouse SLIT family: Secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance
40. The conserved immunoglobulin superfamily member SAX-3/Robo directs multiple aspects of axon guidance in C. elegans