K channels as molecular targets for the treatment of erectile dysfunction

Journal of Andrology

Volumn 23, Issue 5, 2002, Pages

  Christ, George J ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; POTASSIUM CHANNEL; CALCIUM CHANNEL;

CALCIUM MOBILIZATION; CHANNEL GATING; CONFERENCE PAPER; ERECTILE DYSFUNCTION; HUMAN; HYPERPOLARIZATION; NONHUMAN; PENIS ERECTION; PRIORITY JOURNAL; SMOOTH MUSCLE TONE; VASOCONSTRICTION; VASODILATATION; ANIMAL; GENE THERAPY; IMPOTENCE; MALE; METABOLISM; MUSCLE TONE; PHYSIOLOGY; REVIEW; VASCULAR SMOOTH MUSCLE;

ANIMAL; CALCIUM CHANNELS; GENE THERAPY; HUMAN; IMPOTENCE; MALE; MUSCLE TONUS; MUSCLE, SMOOTH, VASCULAR; PENILE ERECTION; POTASSIUM CHANNELS; SUPPORT, U.S. GOV'T, P.H.S.; ANIMALS; HUMANS;

EID: 0036725094     PISSN: 01963635     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (43)

1. Toward understanding the assembly and structure of KATP channels
2. A view of sur/KIR6.X, KATP channels
3. Homotypic, heterotypic and heteromeric gap junction channels
4. Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway
5. The penis as a vascular organ: The importance of corporal smooth muscle tone in the control of erection
6. Erection
7. A new frontier: Gene therapy for erectile dysfunction
8. Gap junctions and ion channels: Relevance to erectile dysfunction
9. Gene therapy: Future strategies and therapies
10. K+ channels and gap junctions in the modulation of corporal smooth muscle tone
11. 2+ in cultured human corporal smooth muscle cells
12. Intracorporal injection of hSlo cDNA in rats produces physiologically relevant alterations in penile function
13. Integrative erectile biology: The role of signal transduction and cell-to-cell communication in coordinating corporal smooth muscle tone and penile erection
14. Characterization of K currents in cultured human corporal smooth muscle cells
15. Ion channels and gap junctions: Their role in erectile physiology, dysfunction and future therapy
16. Interaction of charybdotoxin S1OA with single maxi-K channels: Kinetics of blockade depend on the presence of the beta 1 subunit
17. ATP-sensitive potassium channels: Structures, functions, and pathophysiology
18. The role of Ca2+-activated K+ channel spliced variants in the tonotopic organization of the turtle cochlea
19. Identification of Ca(2+)-activated K+ channel splice variants and their distribution in the turtle cochlea
20. Characterization of tissue-expressed alpha subunits of the high conductance Ca(2+)-activated K+ channel
21. Potassium channel activation: A potential therapeutic approach?
22. Potassium channel openers as potential therapeutic weapons in ion channel disease
23. Peripheral channelopathies as targets for potassium channel openers
24. Characterization of ATP-sensitive potassium channels in human corporal smooth muscle cells
25. ca channel in human corporal smooth muscle
26. Potassium outward currents in freshly dissociated rabbit corpus cavernosum myocytes
27. Integrative erectile biology: The effects of age and disease on gap junctions and ion channels and their potential value to the treatment of erectile dysfunction
28. Vasoconstrictors in erectile physiology
29. New therapies and delivery mechanisms for treatment of erectile dysfunction
30. Neuronal innervation, intracellular signal transduction and intercellular coupling: A model for syncytial tissue responses in the steady state
31. Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum
32. Human and rabbit cavernosal smooth muscle cells express Rho-kinase
33. Gene therapy: Future therapy for erectile dysfunction
34. ATP-sensitive potassium channels: A model of heteromultimeric potassium channel/receptor assemblies
35. K channels and human corporal smooth muscle cell tone: Further evidence for the physiological relevance of the maxi-K channel subtype to the regulation of human corporal smooth muscle tone in vitro
36. Maxi-K(Ca), a unique member of the voltage-gated K channel superfamily
37. - channels and gap junctions in urogenital smooth muscle: Implications for improved understanding of urogenital function, disease and therapy
38. ATP channel openers
39. Characterization of and modulation by a betasubunit of a human maxi KCa channel cloned from myometrium
40. ca) channel in freshly isolated myocytes of human and rat corpora
41. Control of alternative splicing of potassium channels by stress hormones
42. Endothelin-1 as a putative modulator of erectile dysfunction. II. Calcium mobilization in cultured human corporal smooth muscle cells