메뉴 건너뛰기




Volumn 12, Issue , 2000, Pages S15-S25

Gap junctions and ion channels: Relevance to erectile dysfunction

Author keywords

Corporal myocyte; KATP channel; KCa channel; K+ channel gene therapy; Smooth muscle tone; Transmembrane potential

Indexed keywords

ION; POTASSIUM; PROSTAGLANDIN E1; SILDENAFIL;

EID: 0033776875     PISSN: 09559930     EISSN: 14765489     Source Type: Journal    
DOI: 10.1038/sj.ijir.3900573     Document Type: Article
Times cited : (32)

References (106)
  • 1
    • 0028824010 scopus 로고
    • The penis as a vascular organ: The importance of corporal smooth muscle tone in the control of erection
    • Christ GJ. The penis as a vascular organ: The importance of corporal smooth muscle tone in the control of erection. Urologic Clinics of North America 1995; 22: 727-745.
    • (1995) Urologic Clinics of North America , vol.22 , pp. 727-745
    • Christ, G.J.1
  • 2
    • 0002122535 scopus 로고    scopus 로고
    • The vascular physiology of penile erection and pharmacotherapy erectile dysfunction
    • Frishman WH, Sonnenblick EH, McGraw-Hill: Ny
    • Melman A, Christ GJ. The vascular physiology of penile erection and pharmacotherapy erectile dysfunction. In: Frishman WH, Sonnenblick EH, eds. Cardiovascular Phar-macotherapeutics. McGraw-Hill: Ny, 1997, pp 1221-1229.
    • (1997) Cardiovascular Phar-Macotherapeutics , pp. 1221-1229
    • Melman, A.1    Christ, G.J.2
  • 4
    • 0030640228 scopus 로고    scopus 로고
    • The ‘syncytial tissue triad’: A model for understanding how gap junctions participate in the local control of penile erection
    • Christ GJ. The ‘syncytial tissue triad’: A model for understanding how gap junctions participate in the local control of penile erection. World J Urol 1997; 13: 36-44.
    • (1997) World J Urol , vol.13 , pp. 36-44
    • Christ, G.J.1
  • 5
    • 0030758625 scopus 로고    scopus 로고
    • Integrative erectile biology: The role of signal transduction and cell-to-cell communication in coordinating corporal smooth muscle tone and penile erection
    • Christ GJ, Richards S, Winkler A. Integrative erectile biology: The role of signal transduction and cell-to-cell communication in coordinating corporal smooth muscle tone and penile erection. Int J Impot lies 1997; 9: 1-16.
    • (1997) Int J Impot Lies , vol.9 , pp. 1-16
    • Christ, G.J.1    Richards, S.2    Winkler, A.3
  • 6
    • 0027135427 scopus 로고
    • Relationship between contraction and relaxation in human and rabbit corpus cavernosum
    • Taub HC, Lerner SE, Melman A, Christ GJ. Relationship between contraction and relaxation in human and rabbit corpus cavernosum. Urology 1993: 42: 698-704.
    • (1993) Urology , vol.42 , pp. 698-704
    • Taub, H.C.1    Lerner, S.E.2    Melman, A.3    Christ, G.J.4
  • 7
    • 0027167570 scopus 로고
    • Review of erectile dysfunction: New insights and more questions
    • Lerner SE, Melman A, Christ GJ. A review of erectile dysfunction: New insights and more questions. J Urol 1993; 149: 1246-1255.
    • (1993) J Urol , vol.149 , pp. 1246-1255
    • Lerner, S.E.1    Melman, A.2    Christ, G.3
  • 9
    • 0024559857 scopus 로고
    • Impared neurogenic andendothe-lium-mediated relaxation of penile smooth muscle from diabetic mem with impotence
    • Saenz De Tajada I et al. Impared neurogenic andendothe-lium-mediated relaxation of penile smooth muscle from diabetic mem with impotence. New Engl J Med 1989; 320: 1025.
    • (1989) New Engl J Med , vol.320 , pp. 1025
    • Saenz De Tajada, I.1
  • 10
    • 0025822280 scopus 로고
    • Trabecular smooth muscle modulates the capacitor function of the penis studies on a rabbit model
    • Saenz De Tejada I et al. Trabecular smooth muscle modulates the capacitor function of the penis studies on a rabbit model. Am J Physiol 1991; 260: H1590-H1595.
    • (1991) Am J Physiol , vol.260
    • Saenz De Tejada, I.1
  • 11
    • 0032573913 scopus 로고    scopus 로고
    • Update on male erectile dysfunction
    • Wagner G, Saenz De Tejada I. Update on male erectile dysfunction. Br Med J 1998; 316: 678-682.
    • (1998) Br Med J , vol.316 , pp. 678-682
    • Wagner, G.1    Saenz De Tejada, I.2
  • 13
    • 0023228171 scopus 로고
    • Physiology of erection and pharmacologic management of impotence
    • Lue TF, Tanagho EA. Physiology of erection and pharmacologic management of impotence. J Urol 1987; 137: 829-836.
    • (1987) J Urol , vol.137 , pp. 829-836
    • Lue, T.F.1    Tanagho, E.A.2
  • 15
    • 0032445109 scopus 로고    scopus 로고
    • The control of corporal smooth muscle tone, the coordination of penile erection and the etiology of erectile dysfunction: The devil is in the details
    • Christ GJ. The control of corporal smooth muscle tone, the coordination of penile erection and the etiology of erectile dysfunction: The devil is in the details. J Sex Educat Ther 1998; 23: 187-193.
    • (1998) J Sex Educat Ther , vol.23 , pp. 187-193
    • Christ, G.J.1
  • 16
    • 0029919229 scopus 로고    scopus 로고
    • Efficacy and safety of intracavernosal alprostadil in men with erectile dysfunction. The alprosladil study group
    • Linet IO et al. Efficacy and safety of intracavernosal alprostadil in men with erectile dysfunction. The alprosladil study group. New Engl J Med 1996; 334: 873-877.
    • (1996) New Engl J Med , vol.334 , pp. 873-877
    • Linet, I.O.1
  • 17
    • 0030796819 scopus 로고    scopus 로고
    • Intracavernosal forskolin: Role in management of vasculogenic impotence resistant to standard 3-agent pharmacotherapy
    • Mulhall JP et al. Intracavernosal forskolin: Role in management of vasculogenic impotence resistant to standard 3-agent pharmacotherapy. J Urol 1997; 158: 1752-1758.
    • (1997) J Urol , vol.158 , pp. 1752-1758
    • Mulhall, J.P.1
  • 18
    • 0031035913 scopus 로고    scopus 로고
    • Sexual dysfunction in the diabetic BB/WOR rat: A role of central neuropathy
    • Me Vary KT, Rathnau GH, McKenna KE. Sexual dysfunction in the diabetic BB/WOR rat: A role of central neuropathy. Am J Physiol 1997; 272: R259-R267.
    • (1997) Am J Physiol , vol.272
    • Me Vary, K.T.1    Rathnau, G.H.2    McKenna, K.E.3
  • 19
    • 0031805936 scopus 로고    scopus 로고
    • Central control of penile erection
    • McKenna KE. Central control of penile erection. Int J Impot lies 1998; 10(Suppl): S25-S34.
    • (1998) Int J Impot Lies , vol.10
    • McKenna, K.E.1
  • 20
    • 0033023938 scopus 로고    scopus 로고
    • Intracavernous pressure during erection in rats: An integrative approach based on telemetric recording
    • Bernabe J, Rampin O, Sachs BD, Guiliano F. Intracavernous pressure during erection in rats: An integrative approach based on telemetric recording. Am J Physiol 1999; 276: R441-R449.
    • (1999) Am J Physiol , vol.276
    • Bernabe, J.1    Rampin, O.2    Sachs, B.D.3    Guiliano, F.4
  • 22
    • 0002482874 scopus 로고    scopus 로고
    • Origin of resting membrane potentials
    • Speralakis N, 2nd edition. Academic Press: Ny
    • Speralakis N. Origin of resting membrane potentials. In: Speralakis N, (ed). Cell Physiology Source Book, 2nd edition. Academic Press: Ny, 1998, pp 178-206.
    • (1998) Cell Physiology Source Book , pp. 178-206
    • Speralakis, N.1
  • 23
    • 0027493078 scopus 로고
    • Characterization of K currents in cultured human corporal smooth muscle cells
    • Christ GJ, Spray DC, Brink PR. Characterization of K currents in cultured human corporal smooth muscle cells. J Androl-ogy 1993; 14: 319-328.
    • (1993) J Androl-Ogy , vol.14 , pp. 319-328
    • Christ, G.J.1    Spray, D.C.2    Brink, P.R.3
  • 24
    • 0028843317 scopus 로고
    • An analysis of the Maxi-K+ (KCa) channel in cultured human corporal smooth muscle cells
    • Fan SF, Brink PR, Melinan A, Christ GJ. An analysis of the Maxi-K+ (KCa) channel in cultured human corporal smooth muscle cells. J Urol 1995; 153: 818-825.
    • (1995) J Urol , vol.153 , pp. 818-825
    • Fan, S.F.1    Brink, P.R.2    Melinan, A.3    Christ, G.J.4
  • 25
    • 0032789801 scopus 로고    scopus 로고
    • Prostaglandin Ea activates the large conductance Kca channel in human corporal smooth muscle
    • Lee SW et al. Prostaglandin Ea activates the large conductance Kca channel in human corporal smooth muscle. Int J Impot lies 1999; 11: 179-188.
    • (1999) Int J Impot Lies , vol.11 , pp. 179-188
    • Lee, S.W.1
  • 26
    • 0032586652 scopus 로고    scopus 로고
    • Characterization of ATP-sensitive potassium channels in human corporal smooth muscle cells
    • Lee SW, Wang H-Z, Christ GJ. Characterization of ATP-sensitive potassium channels in human corporal smooth muscle cells. Int J Impot Bes 1999; 11: 189-199.
    • (1999) Int J Impot Bes , vol.11 , pp. 189-199
    • Lee, S.W.1    Wang, H.-Z.2    Christ, G.J.3
  • 27
    • 0030758625 scopus 로고    scopus 로고
    • Integrative erectile biology: The role of signal transduction and cell-to-cell communication in coordinating corporal smooth muscle tone and penile erection
    • Christ GJ, Richards S, Winkler A. Integrative erectile biology: The role of signal transduction and cell-to-cell communication in coordinating corporal smooth muscle tone and penile erection. Int J Impot Bes 1997; 9: 1-16.
    • (1997) Int J Impot Bes , vol.9 , pp. 1-16
    • Christ, G.J.1    Richards, S.2    Winkler, A.3
  • 28
    • 0031827271 scopus 로고    scopus 로고
    • Transfection of rat corporal tissue in vivo with hSlo cDNA is associated with physiologically relevant alterations in erectile function
    • Christ GJ et al. Transfection of rat corporal tissue in vivo with hSlo cDNA is associated with physiologically relevant alterations in erectile function. Am J Physiol 1998; 275: H600-H608.
    • (1998) Am J Physiol , vol.275
    • Christ, G.J.1
  • 29
    • 0032803869 scopus 로고    scopus 로고
    • Ion channels and gap junctions: Their role in erectile physiology, dysfunction and future therapy
    • Christ GJ et al. Ion channels and gap junctions: Their role in erectile physiology, dysfunction and future therapy. Mol Urology 1999; 3: 61-74.
    • (1999) Mol Urology , vol.3 , pp. 61-74
    • Christ, G.J.1
  • 30
    • 0002015565 scopus 로고    scopus 로고
    • Melinan A. Molecular studies of human corporal smooth muscle: Implications for the understanding, diagnosis, and treatment of erectile dysfunction
    • Christ GJ, Melinan A. Molecular studies of human corporal smooth muscle: Implications for the understanding, diagnosis, and treatment of erectile dysfunction. Mol Urol 1997; 1: 45-54.
    • (1997) Mol Urol , vol.1 , pp. 45-54
    • Christ, G.J.1
  • 31
    • 0000855199 scopus 로고    scopus 로고
    • New frontier: Gene therapy for erectile dysfunction
    • Morales A, Martin Dunitz Publishers: London
    • Christ GJ. A new frontier: Gene therapy for erectile dysfunction. In: Morales A, (ed). Current Concepts in the Treatment of Erectile Dysfunction, Martin Dunitz Publishers: London, 1998, pp 209-230.
    • (1998) Current Concepts in the Treatment of Erectile Dysfunction , pp. 209-230
    • Christ, G.1
  • 32
    • 0007542802 scopus 로고    scopus 로고
    • Electrophysiological evaluation of K+ channels in enzymatically dissociated myocytes from human and rat corpus cavernosuin
    • Wang H-Z, Lee SW, Christ GJ. Electrophysiological evaluation of K+ channels in enzymatically dissociated myocytes from human and rat corpus cavernosuin. Int J Impot Bes 2000; 12: (In press).
    • (2000) Int J Impot Bes , vol.12
    • Wang, H.-Z.1    Lee, S.W.2    Christ, G.J.3
  • 33
    • 0033023726 scopus 로고    scopus 로고
    • A stretch-sensitive chloride channel in corpora cavernosa myocytes
    • Fan S-F, Christ GJ, Melinan A, Brink PR. A stretch-sensitive chloride channel in corpora cavernosa myocytes. Int J Impot Bes 1999; 11: 1-7.
    • (1999) Int J Impot Bes , vol.11 , pp. 1-7
    • Fan, S.-F.1    Christ, G.J.2    Melinan, A.3    Brink, P.R.4
  • 34
    • 0032427162 scopus 로고    scopus 로고
    • K+ channel modulation in arterial smooth muscle
    • Standen NB, Quayle JM. K+ channel modulation in arterial smooth muscle. Acta Physiol Scand 1998; 164: 549-557.
    • (1998) Acta Physiol Scand , vol.164 , pp. 549-557
    • Standen, N.B.1    Quayle, J.M.2
  • 35
    • 0033977162 scopus 로고    scopus 로고
    • Ion channels and vascular tone
    • Jackson WF. Ion channels and vascular tone. Hypertension 2000; 35: 173-178.
    • (2000) Hypertension , vol.35 , pp. 173-178
    • Jackson, W.F.1
  • 36
    • 0029804854 scopus 로고    scopus 로고
    • Is there a therapeutic future for ‘potassium channel openers’?
    • Lawson K. Is there a therapeutic future for ‘potassium channel openers’? Clinical Science 1996: 91: 651-663.
    • (1996) Clinical Science , vol.91 , pp. 651-663
    • Lawson, K.1
  • 37
    • 0029884796 scopus 로고    scopus 로고
    • Potassium channel activation: A potential therapeutic approach?
    • Lawson K. Potassium channel activation: A potential therapeutic approach? Pharmacol Ther 1996; 70: 39-63.
    • (1996) Pharmacol Ther , vol.70 , pp. 39-63
    • Lawson, K.1
  • 38
    • 0029108913 scopus 로고
    • Physiological roles and properties of potassium channels in arterial smooth muscle
    • Nelson MT, Quayle JM. Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol 1995; 268: C799-C822.
    • (1995) Am J Physiol , vol.268
    • Nelson, M.T.1    Quayle, J.M.2
  • 41
    • 0001701733 scopus 로고    scopus 로고
    • Modulators of large-conductance calcium-activated potassium (BK) channels as potential therapeutic targets
    • Starrett JE, Dworetzky SI, Gribkoff VK. Modulators of large-conductance calcium-activated potassium (BK) channels as potential therapeutic targets. Curr Pharmac Design 1996; 2: 413-428.
    • (1996) Curr Pharmac Design , vol.2 , pp. 413-428
    • Starrett, J.E.1    Dworetzky, S.I.2    Gribkoff, V.K.3
  • 42
    • 0039351106 scopus 로고    scopus 로고
    • Stoichiometry of sulfonylurea-induced ATP-sensitive potassium channel closure
    • Dorschner H et al. Stoichiometry of sulfonylurea-induced ATP-sensitive potassium channel closure. Mol Pharmacol 1999; 55: 1060-1066.
    • (1999) Mol Pharmacol , vol.55 , pp. 1060-1066
    • Dorschner, H.1
  • 43
    • 0028807878 scopus 로고
    • Relaxation of arterial smooth muscle by calcium sparks
    • Nelson M et al. Relaxation of arterial smooth muscle by calcium sparks. Science 1995; 270: 633-637.
    • (1995) Science , vol.270 , pp. 633-637
    • Nelson, M.1
  • 44
    • 0030772859 scopus 로고    scopus 로고
    • ATP-Sensitive and inwardly rectifying potassium channels in smooth muscle
    • Quayle JM, Nelson MT, Standen NB. ATP-Sensitive and inwardly rectifying potassium channels in smooth muscle. Physiol Rev 1997; 77: 1165-1232.
    • (1997) Physiol Rev , vol.77 , pp. 1165-1232
    • Quayle, J.M.1    Nelson, M.T.2    Standen, N.B.3
  • 45
    • 33746732175 scopus 로고    scopus 로고
    • Voltage dependence of Ca2+ sparks in intact cerebral arteries
    • Jaggar JH, Stevenson AS, Nelson MT. Voltage dependence of Ca2+ sparks in intact cerebral arteries. Am J Physiol 1998; 274: C1755-C1761.
    • (1998) Am J Physiol , vol.274
    • Jaggar, J.H.1    Stevenson, A.S.2    Nelson, M.T.3
  • 46
    • 0028325752 scopus 로고
    • Phosphorylation and dephosphorylation modulate a Ca2+-activated K+ channel in rat peptidergic nerve terminals
    • Bielefeldt K, Jackson MB. Phosphorylation and dephosphorylation modulate a Ca2+-activated K+ channel in rat peptidergic nerve terminals. J Physiol 1994; 475: 241-254.
    • (1994) J Physiol , vol.475 , pp. 241-254
    • Bielefeldt, K.1    Jackson, M.B.2
  • 47
    • 0025912627 scopus 로고
    • Protein kinase A activity closely associated with a reconstituted calcium-activated potassium channel
    • Chung S et al. Protein kinase A activity closely associated with a reconstituted calcium-activated potassium channel. Science 1991; 253: 560-562.
    • (1991) Science , vol.253 , pp. 560-562
    • Chung, S.1
  • 48
    • 0030860425 scopus 로고    scopus 로고
    • Ca2+-activated K+ channels regulate action potential depolarization in urinary bladder smooth muscle
    • Ileppner TJ, Bonev AD, Nelson MT. Ca2+-activated K+ channels regulate action potential depolarization in urinary bladder smooth muscle. Am JPhysiol 1997; 273: C110-C117.
    • (1997) Am Jphysiol , vol.273
    • Ileppner, T.J.1    Bonev, A.D.2    Nelson, M.T.3
  • 49
    • 85047679339 scopus 로고
    • Cellular pharmacology of potassium channel openers in vascular smooth muscle [Review]
    • Quast U, Guillon JM, Cavero I. Cellular pharmacology of potassium channel openers in vascular smooth muscle [Review]. Cardiovasc Res 1994; 28: 805-810.
    • (1994) Cardiovasc Res , vol.28 , pp. 805-810
    • Quast, U.1    Guillon, J.M.2    Cavero, I.3
  • 50
    • 0027164694 scopus 로고
    • CGMP-dependent protein kinase activates Ca-activated K channels in cerebral artery smooth muscle cells
    • Robertson BE, Schubert R, Hescheller J, Nelson MT. cGMP-dependent protein kinase activates Ca-activated K channels in cerebral artery smooth muscle cells. Am J Physiol 1993; 265: C299-C303.
    • (1993) Am J Physiol , vol.265
    • Robertson, B.E.1    Schubert, R.2    Hescheller, J.3    Nelson, M.T.4
  • 51
    • 0032620047 scopus 로고    scopus 로고
    • Pharmacome-chanical coupling: The role of calcium, G-proteins, kinases and phosphatases
    • Sornlyo AP, Wu X, Walker LA, Somlyo AV. Pharmacome-chanical coupling: The role of calcium, G-proteins, kinases and phosphatases. Rev Physiol Riochem Pharmcol 1999; 134: 202-234.
    • (1999) Rev Physiol Riochem Pharmcol , vol.134 , pp. 202-234
    • Sornlyo, A.P.1    Wu, X.2    Walker, L.A.3    Somlyo, A.V.4
  • 52
    • 0028043535 scopus 로고
    • Signal transduction and regulation in smooth muscle
    • Somlyo AP, Somlyo AV. Signal transduction and regulation in smooth muscle. Nature 1994; 372: 213-236.
    • (1994) Nature , vol.372 , pp. 213-236
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 53
    • 0032414964 scopus 로고    scopus 로고
    • From pharmacomechanical coupling to G-proteins and myosin phosphatase
    • Somlyo AP, Somlyo AV. From pharmacomechanical coupling to G-proteins and myosin phosphatase. Acta Physiol Scand 1998; 164: 437-448.
    • (1998) Acta Physiol Scand , vol.164 , pp. 437-448
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 57
    • 0027930590 scopus 로고
    • Molecular properties of a superfamily of plasma membrane cation channels
    • Catterall YVA. Molecular properties of a superfamily of plasma membrane cation channels. Curr Opinion Cell Riol 1994; 6: 607-615.
    • (1994) Curr Opinion Cell Riol , vol.6 , pp. 607-615
    • Catterall, Y.V.A.1
  • 58
    • 0030642077 scopus 로고    scopus 로고
    • Multiple types of ion channels in cavernous smooth muscle
    • Noack T, Noack P. Multiple types of ion channels in cavernous smooth muscle. World J Urol 1997; 15: 45-49.
    • (1997) World J Urol , vol.15 , pp. 45-49
    • Noack, T.1    Noack, P.2
  • 59
    • 0026562018 scopus 로고
    • Clinical pharmacology of potassium channel openers
    • Andersson K-E. Clinical pharmacology of potassium channel openers. Pharmacol Toxicol 1992; 70: 244-254.
    • (1992) Pharmacol Toxicol , vol.70 , pp. 244-254
    • Andersson, K.-E.1
  • 60
    • 0000645164 scopus 로고    scopus 로고
    • Intracavernosal (IC) injection of a potassium channel opener to treat erectile dysfunction
    • Benevides MD et al. Intracavernosal (IC) injection of a potassium channel opener to treat erectile dysfunction. J Urol 1999; 161(Suppl): 212: (Abstract #812).
    • (1999) J Urol , vol.161 , pp. 212
    • Benevides, M.D.1
  • 61
    • 0033559739 scopus 로고    scopus 로고
    • Klr2.1 encodes the inward rectifier potassium channel in rat arterial smooth muscle cells
    • Bradley KK et al. Klr2.1 encodes the inward rectifier potassium channel in rat arterial smooth muscle cells. J Physiol (Lond.) 1999; 515: 639-651.
    • (1999) J Physiol (Lond.) , vol.515 , pp. 639-651
    • Bradley, K.K.1
  • 62
    • 0031917466 scopus 로고    scopus 로고
    • Toward understanding the assembly and structure of KAXP channels
    • Aguilar-Bryan L et al. Toward understanding the assembly and structure of KAXP channels. Physiol Rev 1998; 78: 227-245.
    • (1998) Physiol Rev , vol.78 , pp. 227-245
    • Aguilar-Bryan, L.1
  • 64
    • 0032574668 scopus 로고    scopus 로고
    • Genomic organization and expression of KCNJ8/Kir6.1, a gene encoding a subunit of an ATP-sensitive potassium channel
    • Erginel-Unaltuna N, Yang WP, Blanar MA. Genomic organization and expression of KCNJ8/Kir6.1, a gene encoding a subunit of an ATP-sensitive potassium channel. Gene 1998; 211: 71-78.
    • (1998) Gene , vol.211 , pp. 71-78
    • Erginel-Unaltuna, N.1    Yang, W.P.2    Blanar, M.A.3
  • 65
    • 0028972501 scopus 로고
    • Reconstitution of Ikatp: An inward rectifier subunit plus the sulfonylurea receptor
    • Inagaki N et al. Reconstitution of Ikatp: An inward rectifier subunit plus the sulfonylurea receptor. Science 1995; 270: 1166-1170.
    • (1995) Science , vol.270 , pp. 1166-1170
    • Inagaki, N.1
  • 66
    • 0028933233 scopus 로고
    • Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart
    • Inagaki N et al. Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart. J Biol Chem 1995; 270: 5691-5694.
    • (1995) J Biol Chem , vol.270 , pp. 5691-5694
    • Inagaki, N.1
  • 67
    • 0028876116 scopus 로고
    • Seino S. CDNA sequence, gene structure, and chromosomal localization of the human ATP-sensitive potassium channel, uKatp-1, gene (KCNJ8)
    • Inagaki N, Inazawa J, Seino S. cDNA sequence, gene structure, and chromosomal localization of the human ATP-sensitive potassium channel, uKatp-1, gene (KCNJ8). Genomics 1995; 30: 102-104.
    • (1995) Genomics , vol.30 , pp. 102-104
    • Inagaki, N.1    Inazawa, J.2
  • 68
    • 0029743412 scopus 로고    scopus 로고
    • A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel
    • Isomoto S et al. A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel. J Biol Chem 1996; 271: 24321-24324.
    • (1996) J Biol Chem , vol.271 , pp. 24321-24324
    • Isomoto, S.1
  • 69
    • 0033037098 scopus 로고    scopus 로고
    • ATP-sensitive potassium channels: A model of heteromultimeric potassium channel/receptor assemblies
    • Seino S. ATP-sensitive potassium channels: A model of heteromultimeric potassium channel/receptor assemblies. Ann Iiev Physiol 1999; 61: 337-362.
    • (1999) Ann Iiev Physiol , vol.61 , pp. 337-362
    • Seino, S.1
  • 70
    • 0028982802 scopus 로고
    • Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male zucker diabetic laity rats
    • Stoffel M et al. Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male zucker diabetic laity rats. Biochem Biophys Bes Comm 1995; 212: 894-899.
    • (1995) Biochem Biophys Bes Comm , vol.212 , pp. 894-899
    • Stoffel, M.1
  • 71
    • 0039351106 scopus 로고    scopus 로고
    • Stoichiometry of sulfonylurea-induced ATP-sensitive potassium channel closure
    • Dorschner H et al. Stoichiometry of sulfonylurea-induced ATP-sensitive potassium channel closure. J Pharmacol Exp Ther 1999; 55: 1060-1066.
    • (1999) J Pharmacol Exp Ther , vol.55 , pp. 1060-1066
    • Dorschner, H.1
  • 72
    • 0032189924 scopus 로고    scopus 로고
    • Potassium channel openers require ATP to bind to and act through sulfonylurea receptors
    • Schwanstecher M et al. Potassium channel openers require ATP to bind to and act through sulfonylurea receptors. EMBO J 1998; 17: 5529-5535.
    • (1998) EMBO J , vol.17 , pp. 5529-5535
    • Schwanstecher, M.1
  • 73
    • 0028894608 scopus 로고
    • Human calcium-activated potassium channel gene expressed in vascular smooth muscle
    • McCobb DP et al. Human calcium-activated potassium channel gene expressed in vascular smooth muscle. Am J Physiol 1995; 269: H767-H777.
    • (1995) Am J Physiol , vol.269
    • McCobb, D.P.1
  • 74
    • 0029892498 scopus 로고    scopus 로고
    • Cloning of human pancreatic islet large conductance Ca2+-activated K+ channel (HSlo) cDNAs: Evidence for high levels of expression in pancreatic islets and identification of a flanking genetic marker
    • Ferrer J, Wasson J, Salkoff L, Permutt MA. Cloning of human pancreatic islet large conductance Ca2+-activated K+ channel (hSlo) cDNAs: Evidence for high levels of expression in pancreatic islets and identification of a flanking genetic marker. Diabetologia 1996; 39: 891-898.
    • (1996) Diabetologia , vol.39 , pp. 891-898
    • Ferrer, J.1    Wasson, J.2    Salkoff, L.3    Permutt, M.A.4
  • 75
    • 0026413976 scopus 로고
    • A component of calcium-activated potassium channels encoded by the Drosophila slo locus
    • Atkinson NS, Robertson GA, Ganetsky B. A component of calcium-activated potassium channels encoded by the Drosophila slo locus. Science 1991; 253: 551-555.
    • (1991) Science , vol.253 , pp. 551-555
    • Atkinson, N.S.1    Robertson, G.A.2    Ganetsky, B.3
  • 76
    • 0028579516 scopus 로고
    • Cloning, expression, and distribution of functionally distinct Ca2+-activated K+ channel isoforms from human brain
    • Tseng-Crank J et al. Cloning, expression, and distribution of functionally distinct Ca2+-activated K+ channel isoforms from human brain. Neuron 1994; 13: 1315-1330.
    • (1994) Neuron , vol.13 , pp. 1315-1330
    • Tseng-Crank, J.1
  • 77
    • 0027161159 scopus 로고
    • MSlo, a complex mouse gene encoding ‘maxi’ calcium-activated potassium channels
    • Butler A et al. mSlo, a complex mouse gene encoding ‘maxi’ calcium-activated potassium channels. Science 1993; 261: 221-224.
    • (1993) Science , vol.261 , pp. 221-224
    • Butler, A.1
  • 78
    • 0033616777 scopus 로고    scopus 로고
    • Toro L. Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels. A transmembrane β-subunit homolog
    • Wallner M, Meera P, Toro L. Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels. A transmembrane β-subunit homolog. Proc Natl Acad Sci 1999; 96: 4137-4142.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 4137-4142
    • Wallner, M.1    Meera, P.2
  • 79
    • 0033179454 scopus 로고    scopus 로고
    • The role of Ca2+-activated K+ channel spliced variants in the tonotopic organization of the turtle cochlea
    • Jones EMC, Gray-Keller M, Fettiplace R. The role of Ca2+-activated K+ channel spliced variants in the tonotopic organization of the turtle cochlea. J Physiol 1999; 518: 653-665.
    • (1999) J Physiol , vol.518 , pp. 653-665
    • Jones, E.1    Gray-Keller, M.2    Fettiplace, R.3
  • 80
    • 0030612948 scopus 로고    scopus 로고
    • Distribution of Ca2+-activated K+ channel isoforms along the tonotopic gradient of the chicken’s cochlea
    • Rosenblatt KP, Sun ZP, Ileller S, Hudspeth AJ. Distribution of Ca2+-activated K+ channel isoforms along the tonotopic gradient of the chicken’s cochlea. Neuron 1997; 19: 1061-1075.
    • (1997) Neuron , vol.19 , pp. 1061-1075
    • Rosenblatt, K.P.1    Sun, Z.P.2    Ileller, S.3    Hudspeth, A.J.4
  • 81
    • 0033534539 scopus 로고    scopus 로고
    • A molecular mechanism for electrical tuning of cochlear hair cells
    • Rainanathan K et al. A molecular mechanism for electrical tuning of cochlear hair cells. Science 1999; 283: 215-217.
    • (1999) Science , vol.283 , pp. 215-217
    • Rainanathan, K.1
  • 82
    • 0026794812 scopus 로고
    • Calcium-activated potassium channels expressed from cloned complementary DNAs
    • Adelman JP et al. Calcium-activated potassium channels expressed from cloned complementary DNAs. Neuron 1992; 9: 209-216.
    • (1992) Neuron , vol.9 , pp. 209-216
    • Adelman, J.P.1
  • 83
    • 0001671930 scopus 로고    scopus 로고
    • Maxi-KCa, a unique member of the voltage-gated K channel superfamily
    • Toro L, Wallner M, Meera P, Tanaka Y. Maxi-KCa, a unique member of the voltage-gated K channel superfamily. News Physiol Sci 1998; 13: 112-117.
    • (1998) News Physiol Sci , vol.13 , pp. 112-117
    • Toro, L.1    Wallner, M.2    Meera, P.3    Tanaka, Y.4
  • 84
    • 0029810975 scopus 로고    scopus 로고
    • Cloning, expression, and distribution of a Ca2+-activated K+ channel-subunit from human brain
    • Tseng-Crank J et al. Cloning, expression, and distribution of a Ca2+-activated K+ channel-subunit from human brain. Proc Natl Acad Sci 1996; 93: 9200-9205.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 9200-9205
    • Tseng-Crank, J.1
  • 85
    • 0032540395 scopus 로고    scopus 로고
    • Control of alternative splicing of potassium channels by stress hormones
    • Xie J, McCobb DP. Control of alternative splicing of potassium channels by stress hormones. Science 1998; 280: 443-446.
    • (1998) Science , vol.280 , pp. 443-446
    • Xie, J.1    McCobb, D.P.2
  • 86
    • 0029987788 scopus 로고    scopus 로고
    • Distribution of high-conductance Ca2+-activated K+ channels in rat brain: Targeting to axons and nerve terminals
    • Knaus HG et al. Distribution of high-conductance Ca2+-activated K+ channels in rat brain: Targeting to axons and nerve terminals. J Neuroscience 1996: 16: 955-963.
    • (1996) J Neuroscience , vol.16 , pp. 955-963
    • Knaus, H.G.1
  • 87
    • 0032913135 scopus 로고    scopus 로고
    • Human and rodent rnaxi-K channel β-subunit genes: Cloning and characterization
    • Jiang Z, Wallner M, Meera P, Toro L. Human and rodent rnaxi-K channel β-subunit genes: Cloning and characterization. Genomics 1999; 55: 57-67.
    • (1999) Genomics , vol.55 , pp. 57-67
    • Jiang, Z.1    Wallner, M.2    Meera, P.3    Toro, L.4
  • 88
    • 0030994262 scopus 로고    scopus 로고
    • A cysteine-rich domain defined by a novel exon in a Slo variant in rat adrenal chromaffin cells and PC12 cells
    • Saito M, Nelson C, Salkoff L, Lingle CJ. A cysteine-rich domain defined by a novel exon in a Slo variant in rat adrenal chromaffin cells and PC12 cells. J Biol Chem 1997; 272: 11710-11717.
    • (1997) J Biol Chem , vol.272 , pp. 11710-11717
    • Saito, M.1    Nelson, C.2    Salkoff, L.3    Lingle, C.J.4
  • 89
    • 0030857866 scopus 로고    scopus 로고
    • Molecular constituents of maxi KCa channels in human coronary smooth muscle: Predominant ot + fi subunit complexes
    • Tanaka Y et al. Molecular constituents of maxi KCa channels in human coronary smooth muscle: Predominant ot + fi subunit complexes. J Physiol 1997; 502: 545-557.
    • (1997) J Physiol , vol.502 , pp. 545-557
    • Tanaka, Y.1
  • 90
    • 0028168492 scopus 로고
    • Characterization of cAMP accumulation in cultured human corpus cavernosum smooth muscle cells
    • Palmer L et al. Characterization of cAMP accumulation in cultured human corpus cavernosum smooth muscle cells. J Urol 1994; 152: 1308-1314.
    • (1994) J Urol , vol.152 , pp. 1308-1314
    • Palmer, L.1
  • 91
    • 0029967490 scopus 로고    scopus 로고
    • Forskolin: A promising new adjunct to intracavernous pharmacotherapy
    • Cahn DJ, Melinan A, Valcic M, Christ GJ. Forskolin: A promising new adjunct to intracavernous pharmacotherapy. J Urol 1996; 155: 1789-1794.
    • (1996) J Urol , vol.155 , pp. 1789-1794
    • Cahn, D.J.1    Melinan, A.2    Valcic, M.3    Christ, G.J.4
  • 93
    • 77956697871 scopus 로고    scopus 로고
    • Homotypic, heterotypic and heteromeric gap junction channels
    • Perachia C, Academic Press: Ny
    • Brink PR, Valiunas V, Christ GJ. Homotypic, heterotypic and heteromeric gap junction channels. In: Perachia C, (ed). Current Topics in Membranes, Vol 49. Academic Press: Ny, 2000, pp 43-60.
    • (2000) Current Topics in Membranes , vol.49 , pp. 43-60
    • Brink, P.R.1    Valiunas, V.2    Christ, G.J.3
  • 94
    • 77956704527 scopus 로고    scopus 로고
    • Ion permeation through connexin gap junction channels: Effects on conductance and selectivity
    • Perachia C, Academic Press: Ny
    • Veenstra RD. Ion permeation through connexin gap junction channels: Effects on conductance and selectivity. In: Perachia C, (ed). Current Topics in Membranes, Vol 49. Academic Press: Ny, 2000, pp 95-130.
    • (2000) Current Topics in Membranes , vol.49 , pp. 95-130
    • Veenstra, R.D.1
  • 95
    • 0029841675 scopus 로고    scopus 로고
    • Gap junctions in vascular tissues: Evaluating the role of intercellular communication to the modulation of vasomotor tone
    • Christ GJ et al. Gap junctions in vascular tissues: Evaluating the role of intercellular communication to the modulation of vasomotor tone. Circ Res 1996; 79: 631-646.
    • (1996) Circ Res , vol.79 , pp. 631-646
    • Christ, G.J.1
  • 96
    • 0027153392 scopus 로고
    • Gap junctions formed of connexin43 interconnect smooth muscle cells of the human corpus cavernosum
    • Campos de Carvalho AC et al. Gap junctions formed of connexin43 interconnect smooth muscle cells of the human corpus cavernosum. J Urol 1993; 149: 1568-1575.
    • (1993) J Urol , vol.149 , pp. 1568-1575
    • Campos De Carvalho, A.C.1
  • 97
    • 0002497543 scopus 로고    scopus 로고
    • Molecular studies of connexin 43 (Cx43) expression in isolated corporal tissue strips and cultured corporal smooth muscle cells
    • Serels S et al. Molecular studies of connexin 43 (Cx43) expression in isolated corporal tissue strips and cultured corporal smooth muscle cells. Int J Impot Res 1998; 10: 1-9.
    • (1998) Int J Impot Res , vol.10 , pp. 1-9
    • Serels, S.1
  • 98
    • 0027410006 scopus 로고
    • Gap junctional communication between human corpus cavernosum smooth muscle cells in culture: Gating behavior and single channel events
    • Moreno AP, Campos de Carvalho AC, Christ GJ, Spray DC. Gap junctional communication between human corpus cavernosum smooth muscle cells in culture: Gating behavior and single channel events. Am J Physiol 1993; 264: C80-C92.
    • (1993) Am J Physiol , vol.264
    • Moreno, A.P.1    Campos De Carvalho, A.C.2    Christ, G.J.3    Spray, D.C.4
  • 99
    • 0033574546 scopus 로고    scopus 로고
    • An analysis of the presence and physiological relevance of subconducting states of connex-in43-derived gap junction channels in cultured human corporal vascular smooth muscle cells
    • Christ GJ, Brink PR. An analysis of the presence and physiological relevance of subconducting states of connex-in43-derived gap junction channels in cultured human corporal vascular smooth muscle cells. Circ Res 1999; 84: 797-803.
    • (1999) Circ Res , vol.84 , pp. 797-803
    • Christ, G.J.1    Brink, P.R.2
  • 100
    • 33745343125 scopus 로고    scopus 로고
    • Human connexin43 gap junction channel gating: Evidence for mode shifts and/or heterogeneity
    • Brink PR, Ramanan SV, Christ GJ. Human connexin43 gap junction channel gating: Evidence for mode shifts and/or heterogeneity. Am J Physiol 1996; 271: C321-C331.
    • (1996) Am J Physiol , vol.271
    • Brink, P.R.1    Ramanan, S.V.2    Christ, G.J.3
  • 101
    • 0025986754 scopus 로고
    • Intercellular communication through gap junctions: A potential role in pharmacomechanical coupling and syncytial tissue contraction in vascular smooth muscle isolated from the human corpus cavernosum
    • Christ GJ et al. Intercellular communication through gap junctions: A potential role in pharmacomechanical coupling and syncytial tissue contraction in vascular smooth muscle isolated from the human corpus cavernosum. Life Sci 1991; 49: 195-200.
    • (1991) Life Sci , vol.49 , pp. 195-200
    • Christ, G.J.1
  • 102
    • 0000359356 scopus 로고    scopus 로고
    • The ‘syncytial tissue triad’: The mechanistic basis for integrative tissue physiology
    • Christ GJ. The ‘syncytial tissue triad’: The mechanistic basis for integrative tissue physiology. Einstein Quarterly J Biol Med 1999; 15: 179-191.
    • (1999) Einstein Quarterly J Biol Med , vol.15 , pp. 179-191
    • Christ, G.J.1
  • 103
    • 0032493461 scopus 로고    scopus 로고
    • Neuronal innervation, intracellular signal transduction and intercellular coupling: A model for syncytial tissue responses in the steady state
    • Ramanan SV, Brink PR, Christ GJ. Neuronal innervation, intracellular signal transduction and intercellular coupling: A model for syncytial tissue responses in the steady state. J Theor Biol 1998; 193: 69-84.
    • (1998) J Theor Biol , vol.193 , pp. 69-84
    • Ramanan, S.V.1    Brink, P.R.2    Christ, G.J.3
  • 104
    • 0028093223 scopus 로고
    • Dynamic gap junctional communication: A delimiting model for tissue responses
    • Christ GJ, Brink PR, Ramanan SV. Dynamic gap junctional communication: A delimiting model for tissue responses. Biophys J 1994; 67: 1335-1344.
    • (1994) Biophys J , vol.67 , pp. 1335-1344
    • Christ, G.J.1    Brink, P.R.2    Ramanan, S.V.3
  • 105
    • 4243872852 scopus 로고    scopus 로고
    • K+ channel gene therapy is associated with increased nerve-stimulated intracavernous pressure (ICP) responses despite diminished neuronal innervation following 3-4 months of experimental diabetes in rats
    • Christ GJ et al. K+ channel gene therapy is associated with increased nerve-stimulated intracavernous pressure (ICP) responses despite diminished neuronal innervation following 3-4 months of experimental diabetes in rats. FASEB J 1999; 13: A192.
    • (1999) FASEB J , vol.13
    • Christ, G.J.1
  • 106
    • 4243573742 scopus 로고    scopus 로고
    • HSlo transcript is locally restricted after a single intracavernous injection of naked hSlo/pcDNA
    • Day NS et al. hSlo transcript is locally restricted after a single intracavernous injection of naked hSlo/pcDNA. FASEB J 1999; 13: A356.
    • (1999) FASEB J , vol.13
    • Day, N.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.