The YadA protein of Yersinia pseudotuberculosis mediates high-efficiency uptake into human cells under environmental conditions in which invasin is repressed

Infection and Immunity

Volumn 70, Issue 9, 2002, Pages 4880-4891

  Eitel, Julia ^a   Dersch, Petra ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BACTERIAL PROTEIN; BETA1 INTEGRIN; FIBRONECTIN; INVASIN; PROTEIN SERINE THREONINE KINASE; PROTEIN YADA; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; BACTERIUM ADHERENCE; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; REGULATORY MECHANISM; YERSINIA PSEUDOTUBERCULOSIS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADHESINS, BACTERIAL; ANTIGENS, CD29; BACTERIAL ADHESION; CELL LINE; ENZYME INHIBITORS; FIBRONECTINS; GENE EXPRESSION; GENES, BACTERIAL; HUMANS; MAGNESIUM; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; VIRULENCE; YERSINIA PSEUDOTUBERCULOSIS;

EID: 0036719560     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.9.4880-4891.2002     Document Type: Article

References (57)

1. Involvement of focal adhesion kinase in invasin-mediated uptake
2. Efficient uptake of Yersinia pseudotuberculosis via integrin receptors involves a Rac1-Arp 2/3 pathway that bypasses N-WASP function
3. YopE of Yersinia, a GAP for Rho GTPases, selectively modulates Rac-dependent actin structures in endothelial cells
4. Identification of p130Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions
5. The Yersinia pseudotuberculosis adhesin YadA mediates intimate bacterial attachment to and entry into HEp-2 cells
6. Signal transduction in the mammalian cell during bacterial attachment and entry
7. Temperature-inducible outer membrane protein of Yersinia pseudotuberculosis and Yersinia enterocolitica is associated with the virulence plasmid
8. Yersinia enterocolitica: The charisma continues
9. The InIB protein of Listeria monocytogenes is sufficient to promote entry into mammalian cells
10. Phosphoinositide 3-kinase and the regulation of cell growth
11. Phosphoinositide kinases
12. Revised interpretation of the origin of the pSC101 plasmid
13. Role of the transcription activator VirF and the histone-like protein YmoA in the thermoregulation of virulence functions in yersiniae
14. ymoA, a Yersinia enterocolitica chromosomal gene modulating the expression of virulence functions
15. Vitronectin-dependent invasion of epithelial cells by Neisseria gonorrhoeae involves alpha(v) integrin receptors
16. An immunoglobin superfamily-like domain unique to the Yersinia pseudotuberculosis invasin protein is required for stimulation of bacterial uptake via integrin receptors
17. A region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated uptake into mammalian cells and promotes self-association
18. YadA, the multifaceted Yersinia adhesin
19. BAD promoter
20. Crystal structure of invasin: A bacterial integrin-binding protein
21. Reevaluation of the virulence phenotype of the inv yadA double mutants of Yersinia pseudotuberculosis
22. Genetic evidence that the outer membrane protein YOP1 of Yersinia enterocolitica mediates adherence and phagocytosis resistance to human epithelial cells
23. Structure and sequence analysis of Yersinia YadA and Moraxella UspAs reveal a novel class of adhesins
24. Cell adhesion: Old and new questions
25. A role for phosphoinositide 3-kinase in bacterial invasion
26. Determinants for thermoinducible cell binding and plasmid-encoded cellular penetration detected in the absence of the Yersinia pseudotuberculosis invasin protein
27. Multiple beta 1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells
28. Identification of invasin: A protein that allows enteric bacteria to penetrate cultured mammalian cells
29. Temperature-inducible surface fibrillae associated with the virulence plasmid of Yersinia enterocolitica and Yersinia pseudotuberculosis
30. Detection of pathogenic Yersinia enterocolitica in foods and water by immunomagnetic separation, nested polymerase chain reactions, and colorimetric detection of amplified DNA
31. Role of the transcriptional activator, VirF, and temperature in the expression of the pYV plasmid genes of Yersinia enterocolitica
32. A program of Yersinia enterocolitica type III secretion reactions is activated by specific signals
33. Identification of the integrin binding domain of the Yersinia pseudotuberculosis invasin protein
34. A genetic approach to analyzing membrane protein topology
35. Analysis of the role of invasin during Yersinia pseudotuberculosis infection of mice
36. Invasin-dependent and invasin-independent pathways for translocation of Yersinia pseudotuberculosis across the Peyer's patch intestinal epithelium
37. The Yersinia Yops inhibit invasion of Listeria, Shigella and Edwardsiella but not Salmonella into epithelial cells
38. A novel suicide vector and its use in construction of insertion mutations: Osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR
39. Environmental control of invasin expression in Yersinia pseudotuberculosis is mediated by regulation of RovA, a transcriptional activator of the SlyA/Hor family
40. Adhesins as invasins
41. Roles of integrins and fibronectin in the entry of Streptococcus pyogenes into cells via protein F1
42. The biological role of invasin during a Yersinia enterocolitica infection
43. Magnesium metabolism. A review with special reference to the relationship between intracellular content and serum levels
44. Tyrosine protein kinase inhibitors block invasin-promoted bacterial uptake by epithelial cells
45. Translocation of the Yersinia YopE and YopH virulence proteins into target cells is mediated by YopB and YopD
46. Cytotoxic effects of virulent Yersinia pseudotuberculosis on HeLa cells
47. Wortmannin blocks Yersinia invasin-triggered internalization, but not interleukin-8 production by epithelial cells
48. 6
49. Fibronectin-binding protein acts as Staphylococcus aureus invasin via fibronectin bridging to integrin α5β1
50. Expression of antigens encoded by the virulence plasmid of Yersinia enterocolitica under different growth conditions
51. Virulence plasmid-associated autoagglutination in Yersinia spp
52. Listeria monocytogenes, an invasive bacterium, stimulates MAP kinase upon attachment to epithelial cells
53. Bacterial internalization mediated by β1 chain integrins is determined by ligand affinity and receptor density
54. An O antigen can interfere with the function of the Yersinia pseudotuberculosis invasin protein
55. Cellular internalization in the absence of invasin expression is promoted by the Yersinia pseudotuberculosis yadA product