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Volumn 3, Issue 8, 2002, Pages 1191-1195

Vitronectin receptors in vascular disorders

Author keywords

v integrins; v 3 antagonists; Angiogenesis; Occlusion; Osteopontin; Restenosis; Vitronectin

Indexed keywords

3 [[[1 [3 (1H IMIDAZOL 2 YLAMINO)PROPYL] 1H INDAZOL 5 YL]CARBONYL]AMINO] N (MESITYLSULFONYL)ALANINE; ABCIXIMAB; ALPHA V INTEGRIN ANTAGONIST; ARGINYLGLYCYLASPARTIC ACID ANTAGONIST; BETA3 INTEGRIN; CD51 ANTIGEN; GELATINASE A; INDAZOLE DERIVATIVE; INTEGRIN; INTEGRIN ANTAGONIST; INTEGRIN RECEPTOR; ISOXAZOLINE DERIVATIVE; LEUKOCYTE ALPHA4 BETA1 INTEGRIN ANTAGONIST; MONOCLONAL ANTIBODY LM 609; PROTEIN INHIBITOR; SB 223245; SB 273005; SC 72115; THROMBOCYTE ALPHA2B BETA3 INTEGRIN ANTAGONIST; TRANILAST; UNCLASSIFIED DRUG; US 06159964; VASCULAR ALPHA V BETA3 INTEGRIN ANTAGONIST; VITRONECTIN RECEPTOR; WO 00110867; XT 199;

EID: 0036707346     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (11)

References (68)
  • 1
    • 0023058313 scopus 로고
    • Arg-Gly-Asp: A versatile cell recognition sequence
    • Ruoslahti E, Pierchbacker M: Arg-Gly-Asp: A versatile cell recognition sequence. Cell (1986) 44(4):517-518.
    • (1986) Cell , vol.44 , Issue.4 , pp. 517-518
    • Ruoslahti, E.1    Pierchbacker, M.2
  • 2
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation and signaling in cell adhesion
    • Hynes RO: Integrins: Versatility, modulation and signaling in cell adhesion. Cell (1992) 69(1):11-25.
    • (1992) Cell , vol.69 , Issue.1 , pp. 11-25
    • Hynes, R.O.1
  • 3
    • 0001254182 scopus 로고
    • Integrins: Structure, function and biological properties
    • Cheresh D: Integrins: Structure, function and biological properties. Adv Mol Cell Biol (1992) 6:225-252.
    • (1992) Adv Mol Cell Biol , vol.6 , pp. 225-252
    • Cheresh, D.1
  • 4
    • 0028979701 scopus 로고
    • Integrin αv/β1 expression negatively regulates cell growth: Reversal by attachment to fibronectin
    • Varner JA, Emerson DA, Juliano RL: Integrin αv/β1 expression negatively regulates cell growth: Reversal by attachment to fibronectin. Mol Biol Cell (1995) 6(6):725-740.
    • (1995) Mol Biol Cell , vol.6 , Issue.6 , pp. 725-740
    • Varner, J.A.1    Emerson, D.A.2    Juliano, R.L.3
  • 5
    • 0028670298 scopus 로고
    • Integrin αv/β3 rescues melanoma cells from apoptosis in a three-dimensional dermal collagen
    • Montgomery AM, Reisfeld RA, Cheresh DA: Integrin αv/β3 rescues melanoma cells from apoptosis in a three-dimensional dermal collagen. Proc Natl Acad Sci USA (1994) 91(19):8856-8860.
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.19 , pp. 8856-8860
    • Montgomery, A.M.1    Reisfeld, R.A.2    Cheresh, D.A.3
  • 6
    • 0027451706 scopus 로고
    • The extracellular matrix as a cell survival factor
    • Meredith JE, Fazeli B, Schwartz MA: The extracellular matrix as a cell survival factor. Mol Biol Cell (1993) 4(9):953-961.
    • (1993) Mol Biol Cell , vol.4 , Issue.9 , pp. 953-961
    • Meredith, J.E.1    Fazeli, B.2    Schwartz, M.A.3
  • 7
    • 0028670833 scopus 로고
    • Integrin αv/β3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • Brooks PC, Montgomery AM, Rosenfeld M, Reisfeld RA, Hu T, Klier G, Cheresh DA: Integrin αv/β3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell (1994) 79(7):1157-1164.
    • (1994) Cell , vol.79 , Issue.7 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.2    Rosenfeld, M.3    Reisfeld, R.A.4    Hu, T.5    Klier, G.6    Cheresh, D.A.7
  • 8
    • 0034745356 scopus 로고    scopus 로고
    • Rac recruits high-affinity integrin αv/β3 to lamellipodia in endothelial cell migration
    • Kiosses WB, Shattil SJ, Pampori N, Schwartz MA: Rac recruits high-affinity integrin αv/β3 to lamellipodia in endothelial cell migration. Nat Cell Biol (2001) 3:316-320.
    • (2001) Nat Cell Biol , vol.3 , pp. 316-320
    • Kiosses, W.B.1    Shattil, S.J.2    Pampori, N.3    Schwartz, M.A.4
  • 9
    • 0027997413 scopus 로고
    • Selective recognition of cyclic RGD peptides on NMR defined conformation by α-IIb/β3, αv/β3 and α5/β1 integrins
    • Pfaff M, Tangemann K, Müller B, Gurrath M, Müller G, Kessler H, Timpl R, Engel J: Selective recognition of cyclic RGD peptides on NMR defined conformation by α-IIb/β3, αv/β3 and α5/β1 integrins. J Biol Chem (1994) 269(32):20233-20238.
    • (1994) J Biol Chem , vol.269 , Issue.32 , pp. 20233-20238
    • Pfaff, M.1    Tangemann, K.2    Müller, B.3    Gurrath, M.4    Müller, G.5    Kessler, H.6    Timpl, R.7    Engel, J.8
  • 10
    • 0028914586 scopus 로고
    • Peptide ligands for integrin αv/β3 selected from random phage display libraries
    • Healy JM, Murayama O, Maeda T, Yoshino K, Sekiguchi K, Kikuchi M: Peptide ligands for integrin αv/β3 selected from random phage display libraries. Biochemistry (1995) 34(12):3948-3955.
    • (1995) Biochemistry , vol.34 , Issue.12 , pp. 3948-3955
    • Healy, J.M.1    Murayama, O.2    Maeda, T.3    Yoshino, K.4    Sekiguchi, K.5    Kikuchi, M.6
  • 11
    • 0027267959 scopus 로고
    • Selection of peptides binding to the αv/β3 integrin from a phage display library
    • Koivunen E, Gay DA, Ruoslahti E: Selection of peptides binding to the αv/β3 integrin from a phage display library. J Biol Chem (1993) 268(27):20205-20210.
    • (1993) J Biol Chem , vol.268 , Issue.27 , pp. 20205-20210
    • Koivunen, E.1    Gay, D.A.2    Ruoslahti, E.3
  • 12
    • 0027976103 scopus 로고
    • Isolation of a highly specific ligand for the αv/β3 integrin from a phage display library
    • Koivunen E, Wang B, Ruoslahti E: Isolation of a highly specific ligand for the αv/β3 integrin from a phage display library. J Cell Biol (1994) 124(3):373-380.
    • (1994) J Cell Biol , vol.124 , Issue.3 , pp. 373-380
    • Koivunen, E.1    Wang, B.2    Ruoslahti, E.3
  • 13
    • 0029775681 scopus 로고    scopus 로고
    • RGD and other recognition sequences for integrins
    • Ruoslahti E: RGD and other recognition sequences for integrins. Annu Rev Cell Dev Biol (1996) 12:697-715.
    • (1996) Annu Rev Cell Dev Biol , vol.12 , pp. 697-715
    • Ruoslahti, E.1
  • 14
    • 0035004456 scopus 로고    scopus 로고
    • An angiogenic laminin site and its antagonist bind through the αv/β3 and αv/β1 integrins
    • Ponce ML, Nomizu M, Kleinman HK: An angiogenic laminin site and its antagonist bind through the αv/β3 and αv/β1 integrins. FASEB J (2001) 15:1389-1397.
    • (2001) FASEB J , vol.15 , pp. 1389-1397
    • Ponce, M.L.1    Nomizu, M.2    Kleinman, H.K.3
  • 15
    • 0028362876 scopus 로고
    • Requirement of vascular integrin αv/β3 for angiogenesis
    • Brooks PC, Clark RA, Cheresh DA: Requirement of vascular integrin αv/β3 for angiogenesis. Science (1994) 264(5158):569-571.
    • (1994) Science , vol.264 , Issue.5158 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 17
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug to tumor vasculature in a mouse model
    • Arap W, Pasqualini R, Ruoslahti E: Cancer treatment by targeted drug to tumor vasculature in a mouse model. Science (1998) 279(5349):377-380.
    • (1998) Science , vol.279 , Issue.5349 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 18
    • 0033573982 scopus 로고    scopus 로고
    • Synergy between an antiangiogenic integrin αv antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases
    • Lode HN, Moehler T, Xiang B, Jonczyk A, Gillies SD, Cheresh DA, Reisfeld RA: Synergy between an antiangiogenic integrin αv antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases. Proc Natl Acad Sci USA (1999) 96(4):1591-1596.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.4 , pp. 1591-1596
    • Lode, H.N.1    Moehler, T.2    Xiang, B.3    Jonczyk, A.4    Gillies, S.D.5    Cheresh, D.A.6    Reisfeld, R.A.7
  • 19
    • 0029859140 scopus 로고    scopus 로고
    • Antagonists of integrin αv/β3 inhibit renal neovascularization in a murine model
    • Luna J, Tobe T, Mousa SA, Reilly TM, Campochiaro PA: Antagonists of integrin αv/β3 inhibit renal neovascularization in a murine model. Lab Invest (1996) 75(4):563-573.
    • (1996) Lab Invest , vol.75 , Issue.4 , pp. 563-573
    • Luna, J.1    Tobe, T.2    Mousa, S.A.3    Reilly, T.M.4    Campochiaro, P.A.5
  • 20
  • 21
    • 0028670833 scopus 로고
    • Integrin αv/β3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • note
    • Brooks PC, Montgomery AMP, Rosenfeld M, Reisfeld RA, Hu T, Klier G, Cheresh DA: Integrin αv/β3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell (1994) 79(7):1157-1164. This early investigation demonstrated the mechanism of αv/β3 blockade in tumor angiogenesis.
    • (1994) Cell , vol.79 , Issue.7 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.P.2    Rosenfeld, M.3    Reisfeld, R.A.4    Hu, T.5    Klier, G.6    Cheresh, D.A.7
  • 22
    • 0027102818 scopus 로고
    • Conformation/activity studies of rationally designed potent anti-adhesive RGD peptides
    • Gurrath M, Muller G, Kessler H, Aumailley M, Timpl R: Conformation/activity studies of rationally designed potent anti-adhesive RGD peptides. Eur J Biochem (1992) 210(3):911-921.
    • (1992) Eur J Biochem , vol.210 , Issue.3 , pp. 911-921
    • Gurrath, M.1    Muller, G.2    Kessler, H.3    Aumailley, M.4    Timpl, R.5
  • 23
    • 0023609864 scopus 로고
    • Influence of stereochemistry of the sequence Arg-Gly-Asp-Xaa on binding specificity in cell adhesion
    • Pierschbacher MD, Ruoslahti E: Influence of stereochemistry of the sequence Arg-Gly-Asp-Xaa on binding specificity in cell adhesion. J Biol Chem (1987) 262(36):17294-17298.
    • (1987) J Biol Chem , vol.262 , Issue.36 , pp. 17294-17298
    • Pierschbacher, M.D.1    Ruoslahti, E.2
  • 24
    • 0030020835 scopus 로고    scopus 로고
    • Type II to type Ibβ-turn swap changes specificity for integrins
    • Bach AC, Espina JR, Jackson SA, Mousa SA: Type II to type Ibβ-turn swap changes specificity for integrins. J Am Chem Soc (1996) 118(1):293-294.
    • (1996) J Am Chem Soc , vol.118 , Issue.1 , pp. 293-294
    • Bach, A.C.1    Espina, J.R.2    Jackson, S.A.3    Mousa, S.A.4
  • 26
    • 0030924638 scopus 로고    scopus 로고
    • Solid phase synthesis of a selective αv/β3 integrin antagonist library
    • Corbett JW, Graciani NR, Mousa SA, DeGrado WF: Solid phase synthesis of a selective αv/β3 integrin antagonist library. Bioorg Med Chem Lett (1997) 7(11):1371-1376.
    • (1997) Bioorg Med Chem Lett , vol.7 , Issue.11 , pp. 1371-1376
    • Corbett, J.W.1    Graciani, N.R.2    Mousa, S.A.3    Degrado, W.F.4
  • 30
    • 0028150753 scopus 로고
    • Disintegrins and other naturally occurring antagonists of platelet fibrinogen receptors
    • Niewiarowski S, McLane MA, Kloczewiak M, Stewart GJ: Disintegrins and other naturally occurring antagonists of platelet fibrinogen receptors. Semin Hematol (1994) 31(4):289-300.
    • (1994) Semin Hematol , vol.31 , Issue.4 , pp. 289-300
    • Niewiarowski, S.1    McLane, M.A.2    Kloczewiak, M.3    Stewart, G.J.4
  • 31
    • 0029032192 scopus 로고
    • Effect of four disintegrins on the adhesive and metastatic properties of B6F10 melanoma cells in a murine model
    • Beviglia L, Stewart GJ, Niewiarowski S: Effect of four disintegrins on the adhesive and metastatic properties of B6F10 melanoma cells in a murine model. Oncol Res (1995) 7(1):7-20.
    • (1995) Oncol Res , vol.7 , Issue.1 , pp. 7-20
    • Beviglia, L.1    Stewart, G.J.2    Niewiarowski, S.3
  • 33
    • 0038757017 scopus 로고    scopus 로고
    • METH1, a human ortholog of ADAMTS1, and METH-2 are members of a new family of proteins with angio-inhibitory activity
    • Vazquez F, Hastings G, Ortega MA, Lane TF, Oikemus S, Lombardo M, Iruela-Arispe ML: METH1, a human ortholog of ADAMTS1, and METH-2 are members of a new family of proteins with angio-inhibitory activity. J Biol Chem (1999) 274(33):23349-23357.
    • (1999) J Biol Chem , vol.274 , Issue.33 , pp. 23349-23357
    • Vazquez, F.1    Hastings, G.2    Ortega, M.A.3    Lane, T.F.4    Oikemus, S.5    Lombardo, M.6    Iruela-Arispe, M.L.7
  • 37
    • 0033998223 scopus 로고    scopus 로고
    • In vitro and in vivo effects of a cyclic peptide with affinity for the αv/β3 integrin in human melanoma cells
    • Allman R, Cowbum P, Mason M: In vitro and in vivo effects of a cyclic peptide with affinity for the αv/β3 integrin in human melanoma cells. Eur J Cancer (2000) 36(3):410-422.
    • (2000) Eur J Cancer , vol.36 , Issue.3 , pp. 410-422
    • Allman, R.1    Cowbum, P.2    Mason, M.3
  • 38
    • 0031863765 scopus 로고    scopus 로고
    • Combinatorial chemistry techniques applied to nonpeptide integrin antagonists
    • Hoekstra WJ, Poulter BL: Combinatorial chemistry techniques applied to nonpeptide integrin antagonists. Current Med Chem (1998) 5(3):195-204.
    • (1998) Current Med Chem , vol.5 , Issue.3 , pp. 195-204
    • Hoekstra, W.J.1    Poulter, B.L.2
  • 39
    • 0034650403 scopus 로고    scopus 로고
    • A specific sequence of the noncollagenous domain of the α(IV) chain of type IV collagen inhibits expression and activation of matrix metalloproteinases by tumor cells
    • Pasco S, Han J, Gillery P, Bellon G, Maquart FX, Borel JP, Kefalides NA, Monboisse JC: A specific sequence of the noncollagenous domain of the α(IV) chain of type IV collagen inhibits expression and activation of matrix metalloproteinases by tumor cells. Cancer Res (2000) 60(2):467-473.
    • (2000) Cancer Res , vol.60 , Issue.2 , pp. 467-473
    • Pasco, S.1    Han, J.2    Gillery, P.3    Bellon, G.4    Maquart, F.X.5    Borel, J.P.6    Kefalides, N.A.7    Monboisse, J.C.8
  • 40
    • 0033863801 scopus 로고    scopus 로고
    • Ligands to the integrin receptor αv/β3
    • Duggan ME, Hutchinson JH: Ligands to the integrin receptor αv/β3. Exp Opin Ther Pat (2000) 10(9):1367-1383.
    • (2000) Exp Opin Ther Pat , vol.10 , Issue.9 , pp. 1367-1383
    • Duggan, M.E.1    Hutchinson, J.H.2
  • 41
    • 0034283972 scopus 로고    scopus 로고
    • Identification and in vivo efficacy of small-molecule antagonists of integrin αv/β3 (the vitronectin receptor)
    • Miller WH, Keenan RM, Willette RN, Lark MW: Identification and in vivo efficacy of small-molecule antagonists of integrin αv/β3 (the vitronectin receptor). Drug Discovery Today (2000) 5(9):397-408.
    • (2000) Drug Discovery Today , vol.5 , Issue.9 , pp. 397-408
    • Miller, W.H.1    Keenan, R.M.2    Willette, R.N.3    Lark, M.W.4
  • 46
    • 0031862889 scopus 로고    scopus 로고
    • Detection of tumor angiogenesis in vivo by αv/β3-targeted magnetic resonance imaging
    • Sipkins DA, Cheresh DA, Kazemi MR, Nevin LM, Bednarski MD, Li KC: Detection of tumor angiogenesis in vivo by αv/β3-targeted magnetic resonance imaging. Nat Med (1998) 4(5):623-626.
    • (1998) Nat Med , vol.4 , Issue.5 , pp. 623-626
    • Sipkins, D.A.1    Cheresh, D.A.2    Kazemi, M.R.3    Nevin, L.M.4    Bednarski, M.D.5    Li, K.C.6
  • 47
    • 0035706407 scopus 로고    scopus 로고
    • A pilot trial of Vitaxin, a humanized antivitronectin receptor (anti αv/β3) antibody in patients with metastatic cancer
    • note
    • Posey JA, Khazaeli MB, DelGrosso A, Saleh MN, Lin CY, Huse W, LoBuglio AF: A pilot trial of Vitaxin, a humanized antivitronectin receptor (anti αv/β3) antibody in patients with metastatic cancer. Cancer Biother Radiopharm (2001) 16(2):125-132. This pilot study demonstrates the tolerability of the αv/β3 monoclonal antibody, Vitaxin, in cancer patients.
    • (2001) Cancer Biother Radiopharm , vol.16 , Issue.2 , pp. 125-132
    • Posey, J.A.1    Khazaeli, M.B.2    Delgrosso, A.3    Saleh, M.N.4    Lin, C.Y.5    Huse, W.6    Lobuglio, A.F.7
  • 49
    • 0031453118 scopus 로고    scopus 로고
    • Integrin chatter and vascular function in diabetic retinopathy
    • Preissner KT, Kanse SM, Hammes HP: Integrin chatter and vascular function in diabetic retinopathy. Horm Metab Res (1997) 29(12):643-645.
    • (1997) Horm Metab Res , vol.29 , Issue.12 , pp. 643-645
    • Preissner, K.T.1    Kanse, S.M.2    Hammes, H.P.3
  • 50
    • 0034953628 scopus 로고    scopus 로고
    • αv/β3 integrin in angiogenesis and restenosis
    • Kerr JS, Mousa SA, Slee A: αv/β3 integrin in angiogenesis and restenosis. Drug News Perspect (2001) 14:143-150.
    • (2001) Drug News Perspect , vol.14 , pp. 143-150
    • Kerr, J.S.1    Mousa, S.A.2    Slee, A.3
  • 53
    • 0028345255 scopus 로고
    • Randomized trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: Results at six months. The EPIC Investigators
    • Topol EJ, Califf RM, Weisman HF, Tcheng JE, Worley S, Ivanhoe R, George BS, Fintel D, Weston M et al: Randomized trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: Results at six months. The EPIC Investigators. Lancet (1994) 343(8910):881-886.
    • (1994) Lancet , vol.343 , Issue.8910 , pp. 881-886
    • Topol, E.J.1    Califf, R.M.2    Weisman, H.F.3    Tcheng, J.E.4    Worley, S.5    Ivanhoe, R.6    George, B.S.7    Fintel, D.8    Weston, M.9
  • 54
    • 0027367239 scopus 로고
    • Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques
    • Giachelli CM, Bae N, Almeida M, Denhart DT, Alpers CE, Schwartz SM: Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. J Clin Invest (1993) 92(4):1686-1696.
    • (1993) J Clin Invest , vol.92 , Issue.4 , pp. 1686-1696
    • Giachelli, C.M.1    Bae, N.2    Almeida, M.3    Denhart, D.T.4    Alpers, C.E.5    Schwartz, S.M.6
  • 55
    • 0028118893 scopus 로고
    • Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle in vitro
    • Laiw L, Almeida M, Hart C, Schwartz SM, Giachelli CM: Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle in vitro. Circ Res (1994) 74(2):214-224.
    • (1994) Circ Res , vol.74 , Issue.2 , pp. 214-224
    • Laiw, L.1    Almeida, M.2    Hart, C.3    Schwartz, S.M.4    Giachelli, C.M.5
  • 56
    • 0028855585 scopus 로고
    • The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of αv/β3 in smooth muscle cell migration to osteopontin in vitro
    • Liaw L, Skinner MP, Raines EW, Ross R, Cheresh DA, Schwartz SM, Giachelli CM: The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of αv/β3 in smooth muscle cell migration to osteopontin in vitro. J Clin Invest (1995) 95(2):713-724.
    • (1995) J Clin Invest , vol.95 , Issue.2 , pp. 713-724
    • Liaw, L.1    Skinner, M.P.2    Raines, E.W.3    Ross, R.4    Cheresh, D.A.5    Schwartz, S.M.6    Giachelli, C.M.7
  • 57
    • 0028137599 scopus 로고
    • Inhibition of neointimal hyperplasia by blocking αv/β3 integrin with a small peptide antagonist GpenGRGDSPCA
    • Choi ET, Engel L, Callow AD, Sun S, Trachtenberg J, Santoro S, Ryan US: Inhibition of neointimal hyperplasia by blocking αv/β3 integrin with a small peptide antagonist GpenGRGDSPCA. J Vasc Surg (1994) 19(1):125-134.
    • (1994) J Vasc Surg , vol.19 , Issue.1 , pp. 125-134
    • Choi, E.T.1    Engel, L.2    Callow, A.D.3    Sun, S.4    Trachtenberg, J.5    Santoro, S.6    Ryan, U.S.7
  • 58
    • 0031456703 scopus 로고    scopus 로고
    • Selective αv/β3 integrin blockade potently limits neointimal hyperplasia and lumen stenosis following deep coronary arterial stent injury: Evidence for the functional importance of integrin αv/β3 and ospteopontin expression during neointima formation
    • Srivatsa SS, Fitzpatrick LA, Tsao PW, Reilly TM, Holmes DR, Schwartz RS, Mousa SA: Selective αv/β3 integrin blockade potently limits neointimal hyperplasia and lumen stenosis following deep coronary arterial stent injury: Evidence for the functional importance of integrin αv/β3 and ospteopontin expression during neointima formation. Cardiovasc Res (1997) 36(3):408-428.
    • (1997) Cardiovasc Res , vol.36 , Issue.3 , pp. 408-428
    • Srivatsa, S.S.1    Fitzpatrick, L.A.2    Tsao, P.W.3    Reilly, T.M.4    Holmes, D.R.5    Schwartz, R.S.6    Mousa, S.A.7
  • 59
    • 0033546369 scopus 로고    scopus 로고
    • Vitaxin, a humanized monoclonal antibody to the vitronectin receptor (αv/β3), reduces neointimal hyperplasia and total vessel area after balloon injury in hypercholesterolemic rabbits
    • Coleman KR, Braden GA, Willingham MC, Sane DC: Vitaxin, a humanized monoclonal antibody to the vitronectin receptor (αv/β3), reduces neointimal hyperplasia and total vessel area after balloon injury in hypercholesterolemic rabbits. Circ Res (1999) 84(11):1268-1276.
    • (1999) Circ Res , vol.84 , Issue.11 , pp. 1268-1276
    • Coleman, K.R.1    Braden, G.A.2    Willingham, M.C.3    Sane, D.C.4
  • 60
    • 0028136961 scopus 로고
    • Diffuse calcification in human coronary arteries: Association of osteopontin with atherosclerosis
    • Fitzpatrick LA, Severson A, Edwards WD, Ingram RT: Diffuse calcification in human coronary arteries: Association of osteopontin with atherosclerosis. J Clin Invest (1994) 94(4):1597-1604.
    • (1994) J Clin Invest , vol.94 , Issue.4 , pp. 1597-1604
    • Fitzpatrick, L.A.1    Severson, A.2    Edwards, W.D.3    Ingram, R.T.4
  • 61
    • 0035836579 scopus 로고    scopus 로고
    • Vitronectin αv/β3 receptor blockade reduces restenosis and intramural marcophage infiltration associated with a reduction in cellular adhesion molecule expression following balloon angioplasty of the atherosclerotic rabbit femoral artery
    • note
    • Bishop G, McPherson JA, Sanders J, Hesselbacher S, Feldman ML, Gimple LW, Powers E, Mousa SA, Sarembock IJ: Vitronectin αv/β3 receptor blockade reduces restenosis and intramural marcophage infiltration associated with a reduction in cellular adhesion molecule expression following balloon angioplasty of the atherosclerotic rabbit femoral artery. Circulation (2001) 103:1906-1911. This study showed the extended role of integrin αv/β3 in enhancing inflammation, leading to plaque instability.
    • (2001) Circulation , vol.103 , pp. 1906-1911
    • Bishop, G.1    McPherson, J.A.2    Sanders, J.3    Hesselbacher, S.4    Feldman, M.L.5    Gimple, L.W.6    Powers, E.7    Mousa, S.A.8    Sarembock, I.J.9
  • 62
    • 0027367239 scopus 로고
    • Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques
    • Giachelli CM, Bae N, Almeida M, Denhardt DT, Alpers CE, Schwartz SM: Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. J Clin Invest (1993) 92(4):1686-1696.
    • (1993) J Clin Invest , vol.92 , Issue.4 , pp. 1686-1696
    • Giachelli, C.M.1    Bae, N.2    Almeida, M.3    Denhardt, D.T.4    Alpers, C.E.5    Schwartz, S.M.6
  • 63
    • 0028118893 scopus 로고
    • Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro
    • Liaw L, Almeida M, Hart C et al: Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circ Res (1993) 74(2):214-224.
    • (1993) Circ Res , vol.74 , Issue.2 , pp. 214-224
    • Liaw, L.1    Almeida, M.2    Hart, C.3
  • 64
    • 0028855585 scopus 로고
    • The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of αv/β3 in smooth muscle cell migration to osteopontin in vitro
    • Liaw L, Skinner MP, Raines EW et al: The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of αv/β3 in smooth muscle cell migration to osteopontin in vitro. J Clin Invest (1995) 95(2):713-724.
    • (1995) J Clin Invest , vol.95 , Issue.2 , pp. 713-724
    • Liaw, L.1    Skinner, M.P.2    Raines, E.W.3
  • 65
    • 0027944516 scopus 로고
    • Inhibition of integrin function by a cyclic RGD-containing peptide prevents neointima formation
    • Matsuno H, Stassen JM, Vermylen J, Deckmyn H: Inhibition of integrin function by a cyclic RGD-containing peptide prevents neointima formation. Circulation (1994) 90(5):2203-2206.
    • (1994) Circulation , vol.90 , Issue.5 , pp. 2203-2206
    • Matsuno, H.1    Stassen, J.M.2    Vermylen, J.3    Deckmyn, H.4
  • 66
    • 0027936452 scopus 로고
    • Role of angiogenesis in patients with cerebral ischemic stroke
    • Krupinski J, Kaluza J, Kumar P, Kumar S, Wang JM: Role of angiogenesis in patients with cerebral ischemic stroke. Stroke (1994) 25:17894-17898.
    • (1994) Stroke , vol.25 , pp. 17894-17898
    • Krupinski, J.1    Kaluza, J.2    Kumar, P.3    Kumar, S.4    Wang, J.M.5
  • 67
    • 0033496252 scopus 로고    scopus 로고
    • Activated microvessels express vascular endothelial growth factor and integrin αv/β3 during focal cerebral ischemia
    • Abumiya T, Lucero J, Heo JH et al: Activated microvessels express vascular endothelial growth factor and integrin αv/β3 during focal cerebral ischemia. J Cereb Blood Flow Metab (1999) 19(9):1038-1050.
    • (1999) J Cereb Blood Flow Metab , vol.19 , Issue.9 , pp. 1038-1050
    • Abumiya, T.1    Lucero, J.2    Heo, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.