Changes in metabotropic glutamate receptor 1-8 gene expression in the rodent basal ganglia motor loop following lesion of the nigrostriatal tract

Neuropharmacology

Volumn 43, Issue 2, 2002, Pages 261-271

  Messenger, M J ^a   Dawson, L G ^a   Duty, S ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

6 hydroxydopamine; Basal ganglia; mGlu receptor; Motor loop; mRNA; Nigrostriatal tract lesion; Parkinson's disease; Rat

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMIC ACID; MESSENGER RNA; METABOTROPIC RECEPTOR; OXIDOPAMINE; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN INJURY; BRAIN REGION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; MALE; NEUROTRANSMISSION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; RNA ANALYSIS; STRIATONIGRAL DEGENERATION; TRANSCRIPTION REGULATION;

ANIMALS; BASAL GANGLIA; CORPUS STRIATUM; GENE EXPRESSION REGULATION; MALE; NEURAL PATHWAYS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; RNA, MESSENGER; SUBSTANTIA NIGRA;

EID: 0036669625     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00090-4     Document Type: Article

References (41)

1. Aguirre J.A., Andbjer B., Gonzalez-Baron S., Hansson A., Stromberg I., Agnati L.F., Fuxe K. Group I mGluR antagonist AIDA protects nigral DA cells from MPTP-induced injury. Neuroreport. 12:2001;2615-2617.
2. Blandini F., Porter R.H., Greenamyre J.T. Glutamate and Parkinson's disease. Molecular Neurobiology. 12:1996;73-94.
3. Blandini F., Nappi G., Tassorelli C., Martignoni E. Functional changes of the basal ganglia circuitry in Parkinson's disease. Progress in Neurobiology. 62:2000;63-88.
4. Bradley S.R., Standaert D.G., Rhodes K.J., Rees H.D., Testa C.M., Levey A.I., Conn P.J. Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia. Journal of Comparative Neurology. 407:1999;33-46.
5. Bradley S.R., Standaert D.G., Levey A.I., Conn P.J. Distribution of group III mGluRs in rat basal ganglia with subtype-specific antibodies. Annals of the New York Academy of Sciences. 868:1999;531-534.
6. Bradley S.R., Marino M.J., Wittmann M., Rouse S.T., Awad H., Levey A.I., Conn P.J. Activation of group II metabotropic glutamate receptors inhibits synaptic excitation of the substantia nigra pars reticulata. Journal of Neuroscience. 20:2000;3085-3094.
7. Bruno V., Battaglia G., Casabona G., Copani A., Caciagli F., Nicoletti F. Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-b. Journal of Neuroscience. 18:1998;9594-9600.
8. Cartmell J., Schoepp D.D. Regulation of neurotransmitter release by metabotropic glutamate receptors. Journal of Neurochemistry. 75:2000;889-907.
9. A receptor subunit gene expression in the rodent basal ganglia and thalamus. Neuroscience. 95:2000;119-126.
10. 3H]GABA release from rat globus pallidus slices and reverses akinesia following intrapallidal injection in the reserpine-treated rat. British Journal of Pharmacology. 130:2000;1927-1932.
11. Dawson L., Chadha A., Megalou M., Duty S. The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine-treated rat. British Journal of Pharmacology. 129:2000;541-546.
12. Fort P.L., Marty M., Piechaczyk E., El Sabrouty S., Dani C., Jeanteur P., Blanchard J.M. Various adult rat tissues express only one major mRNA species from the glyceraldehydes-3-phosphate dehydrogenase multigenic family. Nucleic Acids Research. 13:1985;1431-1441.
13. Hefti F., Melamed E., Sahakian B.J., Wurtman R.J. Circling behaviour in rats with partial unilateral nigrostriatal tract lesions: effects of amphetamine, apomorphine and DOPA. Pharmacology, Biochemistry and Behaviour. 12:1980;185-188.
14. Isaacson J.S. Spillover in the spotlight. Current Biology. 10:2000;R475-R477.
15. 3H]mazindol autoradiography. Journal of Neuroscience. 5:1985;1513-1521.
16. Konieczny J., Ossowska K., Wolfarth S., Pilc A. LY354740, a group II metabotropic glutamate receptor agonist with potential antiparkinsonian properties in rats. Naunyn Schmiedeberg's Archives of Pharmacology. 358:1998;500-502.
17. Kosinski C.M., Standaert D.G., Testa C.M., Penney J.B., Young A.B. Expression of metabotropic glutamate receptor 1 isoforms in the substantia nigra pars compacta of the rat. Neuroscience. 86:1998;783-798.
18. Kosinski C.M., Risso B.S., Conn P.J., Levey A.I., Landwehrmeyer G.B., Penney J.B., Young A.B., Standaert D.G. Localization of metabotropic glutamate receptor 7 mRNA and mGluR7a protein in the rat basal ganglia. Journal of Comparative Neurology. 415:1999;266-284.
19. Laurie D.J., Schoeffter P., Wiederhold K.H., Sommer B. Cloning, distribution and functional expression of the human mGlu6 metabotropic glutamate receptor. Neuropharmacology. 36:1997;145-152.
20. Lang A.E., Lozano A.M. Parkinson's disease - Part 2. New England Journal Medicine. 339:1998;1044-1053.
21. Lang A.E., Lozano A.M. Parkinson's disease - Part 1. New England Journal Medicine. 339:1998;1130-1143.
22. 3H]-aspartate output in rat striatum. British Journal of Pharmacology. 110:1993;1407-1412.
23. Marino M.J., Wittmann M., Bradley S.R., Hubert G.W., Smith Y., Conn P.J. Activation of group I metabotropic glutamate receptors produces a direct excitation and disinhibition of GABAergic projection neurons in the substantia nigra pars reticulata. Journal of Neuroscience. 21:2001;7001-7012.
24. +-induced neurotoxicity along with brain-derived neurotrophic factor induction. Journal of Neurochemistry. 76:2001;351-360.
25. Meshul C.K., Cogen J.P., Cheng H.W., Moore C., Krentz L., McNeill T.H. Alterations in rat striatal glutamate synapses following a lesion of the cortico- and/or nigrostriatal pathway. Experimental Neurology. 165:2000;191-206.
26. Nicoletti F., Bruno V., Catania M.V., Battaglia G., Copani A., Barbagallo G., Cena V., Sanchez-Prieto J., Spano P.F., Pizzi M. Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection. Neuropharmacology. 38:1999;1477-1484.
27. Ossowska K., Konieczny J., Wolfarth S., Wieronska J., Pilc A. Blockade of the metabotropic glutamate receptor subtype 5 (mGluR5) produces antiparkinsonian-like effects in rats. Neuropharmacology. 41:2001;413-420.
28. Ottersen O.P., Landsend A.S. Organization of glutamate receptors at the synapse. European Journal of Neuroscience. 9:1997;2219-2224.
29. Parent A., Hazrati L.N. Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop. Brain Research Reviews. 20:1995;91-127.
30. Paxinos G., Watson C., 1986. The Rat Brain in Stereotaxic Coordinates. 2nd ed. Academic Press, London, UK.
31. Petralia R.S., Wang Y.X., Niedzielski A.S., Wenthold R.J. The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations. Neuroscience. 71:1996;949-976.
32. Pisani A., Calabresi P., Centonze D., Bernardi G. Activation of group III metabotropic glutamate receptors depresses glutamatergic transmission at corticostriatal synapse. Neuropharmacology. 36:1997;845-851.
33. Rodriguez M.C., Obeso J.A., Olanow C.W. Subthalamic nucleus-mediated excitotoxicity in Parkinson's disease: a target for neuroprotection. Annals of Neurology. 44:1998;S175-S188.
34. Rodriguez-Puertas R., Herrera-Marschitz M., Koistinaho J., Hokfelt T. Dopamine D1 receptor modulation of glutamate receptor messenger RNA levels in the neocortex and neostriatum of unilaterally 6-hydroxydopamine-lesioned rats. Neuroscience. 89:1999;781-797.
35. Rouse S.T., Marino M.J., Bradley S.R., Awad H., Wittmann M., Conn P.J. Distribution and roles of metabotropic glutamate receptors in the basal ganglia motor circuit: implications for treatment of Parkinson's disease and related disorders. Pharmacology and Therapeutics. 88:2000;427-435.
36. Saugstad J.A., Kinzie J.M., Shinohara M.M., Segerson T.P., Westbrook G.L. Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile. Molecular Pharmacology. 51:1997;119-125.
37. Smith Y., Bevan M.D., Shink E., Bolam J.P. Microcircuitry of the direct and indirect pathways of the basal ganglia. Neuroscience. 86:1998;353-387.
38. Testa C.M., Standaert D.G., Young A.B., Penney J.B. Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat. Journal of Neuroscience. 14:1994;3005-3018.
39. Testa C.M., Friberg I.K., Weiss S.W., Standaert D.G. Immunohistochemical localization of metabotropic glutamate receptors mGluR1a and mGluR2/3 in the rat basal ganglia. Journal of Comparative Neurology. 390:1998;5-19.
40. Wittmann M., Marino M.J., Bradley S.R., Conn P.J. Activation of group III mGluRs inhibits GABAergic and glutamatergic transmission in the substantia nigra pars reticulata. Journal of Neurophysiology. 85:2001;1960-1968.
41. Wolfarth S., Konieczny J., LorencKoci E., Ossowska K., Pilc A. The role of metabotropic glutamate receptor (mGluR) ligands in parkinsonian muscle rigidity. Amino Acids. 19:2000;95-101.