Expression of metabotropic glutamate receptor 1 isoforms in the substantia nigra pars compacta of the rat

Neuroscience

Volumn 86, Issue 3, 1998, Pages 783-798

  Kosinski, C M ^a   Standaert, D G ^a   Testa, C M ^a   Penney Jr , J B ^a   Young, A B ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Basal ganglia; Excitotoxicity; Metabotropic glutamate receptors; Parkinson's disease; Rat; Substantia nigra

Indexed keywords

METABOTROPIC RECEPTOR; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ARTICLE; DENDRITE; DOPAMINERGIC NERVE CELL; IN SITU HYBRIDIZATION; MALE; NERVE FIBER; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SOMATIC CELL; SUBSTANTIA NIGRA;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; AXONS; BASE SEQUENCE; DENDRITES; EPITOPES; HUMANS; MALE; MOLECULAR SEQUENCE DATA; NEURONS; OLIGONUCLEOTIDE PROBES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SUBSTANTIA NIGRA; VARIATION (GENETICS);

EID: 0031806842     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(97)00654-4     Document Type: Article

References (47)

1. Albin R. and Greenamyre J. (1992) Alternative excitotoxic hypotheses. Neurology 42, 733-738.
2. Altschul S., Gish S. F., Miller W., Myers E. and Lipman D. (1990) Basic local alignment search tool. J. molec. Biol. 215, 403-410.
3. Ambrosini A., Bresciani L., Fracchia S., Brunello N. and Racagni G. (1995) Metabotropic glutamate receptors negatively coupled to adenylate cyclase inhibit N-methyl-D-aspartate receptor activity and prevent neurotoxicity in mesencephalic neurons in vitro. Molec. Pharmac. 47, 1057-1064.
4. Aramori I. and Nakanishi S. (1992) Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluR 1, in transfected CHO cells. Neuron 8, 757-765.
5. Baude A., Nusser Z., Roberts J. D. B., Mulvihill E., McIlhinney R. A. J. and Somogyi P. (1993) The metabotropic glutamate receptor (mGluR 1α) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction. Neuron 11, 771-787.
6. Bruno V., Copani A., Battaglia G., Raffaele R., Shinozaki H. and Nicoletti F. (1994) Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death. Eur. J. Pharmac. 256, 109-112.
7. Chiamulera C., Albertini P., Valerio D. and Reggiani A. (1992) Activation of metabotropic receptors shows a neuroprotective effect in a rodent model of focal ischemia. Eur. J. Pharmac. 216, 335-336.
8. Flor P. J., Gomeza J., Tones M. A., Kuhn R., Pin J.-P. and Knöpfel T. (1996) The C-terminal domain of the mGluR 1 metabotropic glutamate receptor affects sensitivity to agonists. J. Neurochem. 67, 58-63.
9. Fotuhi M., Sharp A. H., Glatt C. E., Hwang P. M., von Krosigk M., Snyder S. H. and Dawson T. M. (1993) Differential localization of phosphoinositide-linked metabotropic glutamate receptor (mGluRl) and the inositol 1,4,5-trisphosphate receptor in rat brain. J. Neurosci. 13, 2001-2012.
10. Gabellini N., Manev R. M., Candeo P., Favaron M. and Manev H. (1993) Carboxyl domain of glutamate receptor directs its coupling to metabolic pathways. NeuroReport 4, 531-534.
11. Gomeza J., Joly C., Kuhn R., Knöpfel T., Bockaert J. and Pin J.-P. (1996) The second intracellular loop of the metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins. J. biol. Chem. 271, 2199-2205.
12. Grandes P., Mateos J. M., Ruegg D., Kuhn R. and Knopfel T. (1994) Differential cellular localization of three splice variants of the mGluRl metabotropic glutamate receptor in rat cerebellum. NeuroReport 5, 2249-2252.
13. Hampson D. R., Theriault E., Huang X. P., Kristensen P., Pickering D. S., Franck J. E. and Mulvihill E. R. (1994) Characterization of two alternatively spliced forms of a metabotropic glutamate receptor in the central nervous system of the rat. Neuroscience 60, 325-336.
14. Houamed K. M., Kuijper J. L., Gilbert T. L., Haldeman B. A., O'Hara P. J., Mulvihill E. R., Almers W. and Hagen F. S. (1991) Cloning, expression, and gene structure of a G protein-coupled glutamate receptor from rat brain. Science 252, 1318-1321.
15. Johnson R. R., Jiang X. P. and Burkhalter A. (1996) Regional and laminar differences in synaptic localization of NMDA receptor subunit NR1 splice variants in rat visual cortex and hippocampus. J. comp. Neurol. 368, 335-355.
16. Joly C., Gomeza J., Brabet I., Curry K., Bockaert J. and Pin J. P. (1995) Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluRl. J. Neurosci. 15, 3970-3981.
17. Kosinski C., Cha J., Young A., Persichetti F., MacDonald M., Gusella J., Penney J. and Standaert D. (1997) Huntingtin immunoreactivity in the rat neostriatum: differential accumulation in projection and interneurons. Expl Neurol. 144, 239-247.
18. Landwehrmeyer G. B., Standaert D. G., Testa C. M., Penney J. B. and Young A. B. (1995) NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum. J. Neurosci. 15, 5297-5307.
19. Laurie D., Hiltscher R., Boddeke H., Berthele A., Toelle T., Seuwen K. and Sommer B. (1996) Distribution and functional analysis of human mGluR1 receptor splice variants. Neuropharmacology 35, A18.
20. Laurie D. J., Boddeke H. W. G. M., Hiltscher R. and Sommer B. (1996) HmGlu1d, a novel splice variant of the human type I metabotropic glutamate receptor. Eur. J. Pharmac. 296, R1-R3.
21. Makoff A. J., Phillips T., Pilling C. and Emson P. (1996) Cloning of a novel splice variant of human mGluR1. NeuroReport 8, 2943-2947.
22. Martin L. J., Blackstone C. D., Huganir R. L. and Price D. L. (1992) Cellular localization of a metabotropic glutamate receptor in rat brain. Neuron 9, 259-270.
23. McDonald J., Fix A., Tizzano J. and Schoepp D. (1993) Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist. J. Neurosci. 13, 4445-4455.
24. McDonald J. W. and Schoepp D. D. (1992) The metabotropic excitatory amino acid receptor agonist 1S,3R-ACPD selectively potentiates N-methyl-D-aspartate-induced brain injury. Eur. J. Pharmac. 215, 353-354.
25. Mercuri N., Stratta F., Calabresi P., Bonci A. and Bernardi G. (1993) Activation of metabotropic glutamate receptors induced an inward current in rat dopamine mesencephalic neurons. Neuroscience 56, 399-407.
26. Minakami R., Katsuki F. and Sugiyama H. (1993) A variant of metabotropic glutamate receptor subtype 5: an evolutionally conserved insertion with no termination codon. Biochem. biophys. Res. Commun. 194, 622-627.
27. Nakanishi S. (1992) Molecular diversity of glutamate receptors and implications for brain function. Science 258, 597-603.
28. Nicoletti F., Bruno V., Copani A., Casabona G. and Knöpfel T. (1996) Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?. Trends Neurosci. 19, 267-271.
29. Orlando L. R., Standaert D. G., Penney J. B. and Young A. B. (1995) Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions. Neurosci. Lett. 202, 109-112.
30. Pickering D. S., Thomsen C., Suzdak P. D., Fletcher E. J., Robitaille R., Salter M. W., MacDonald J. F., Huang X.-P. and Hampson D. R. (1993) A comparison of two alternatively spliced forms of a metabotropic glutamate receptor coupled to phosphoinositide turnover. J. Neurochem. 61, 85-92.
31. Pin J. P. and Duvoisin R. (1995) Neurotransmitter receptors I: the metabotropic glutamate receptors: structure and functions. Neuropharmacology 34, 1-26.
32. Pin J. P., Joly C., Heinemann S. F. and Bockaert J. (1994) Domains involved in the specificity of G-protein activation in phospholipase C-coupled metabotropic glutamate receptors. Eur. molec. Biol. Org. J. 13, 342-348.
33. Pin J. P., Waeber C., Prezeau L., Bockaert J. and Heinemann S. F. (1992) Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes. Proc. natn. Acad. Sci. U.S.A. 89, 10,331-10,335.
34. Prézeau L., Gomeza J., Ahern S., Mary S., Galvez T., Bockaert J. and Pin J.-P. (1995) Changes in the carboxyl-terminal domain of the metabotropic glutamate receptor 1 by alternative spicing generate receptors with differing agonist-independent activity. Molec. Pharmac. 49, 422-429.
35. Schoepp D.D. and Conn P. J. (1993) Metabotropic glutamate receptors in brain function and pathology. Trends pharmac. Sci. 14, 13-20.
36. Seal A. J., Collingridge G. L. and Henley J. M. (1994) In vitro translation and membrane topology of rat recombinant mGluR1α. Neuropharmacology 33, 1065-1070.
37. Shigemoto R., Kulik A., Roberts J. D. B., Ohishi H., Nusser Z., Kaneko T. and Somogyi P. (1996) Target-cell-specific concentration of a metabotropic glutamate receptor in the presynaptic active zone. Nature 381, 523-525.
38. Shigemoto R., Nakanishi S. and Mizuno N. (1992) Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ hybridization study in adult and developing rat. J. comp. Neurol. 322, 121-135.
39. Smolen A. J. and Beaston-Wimmer P. (1990) Quantitative analysis of in situ hybridization using image analysis. In In Situ Hybridization Histochemistry (ed. Chesselet M. F.), pp. 175-188. CRC, Boca Raton.
40. Takahashi K., Tsuchida K., Tanabe Y., Masu M. and Nakanishi S. (1993) Role of the large extracellular domain of metabotropic glutamate receptors in agonist selectivity determination. J. biol. Chem. 268, 19,341-19,345.
41. Tanabe Y., Masu M., Ishii T., Shigemoto R. and Nakanishi S. (1992) A family of metabotropic glutamate receptors. Neuron 8, 169-179.
42. Testa C. M., Friberg I. K., Weiss S. W. and Standaert D. G. (1998) Immunohistochemical localization of metabotropic glutamate receptors mGluR1a and mGluR2/3 in the rat basal ganglia. J. comp. Neurol. 390, 5-19.
43. Testa C. M., Standaert D. G., Landwehrmeyer G. B., Penney Jr J. B. and Young A. B. (1995) Differential expression of mGluR5 metabotropic glutamate receptor mRNA by rat striatal neurons. J. comp. Neurol. 354, 241-252.
44. Testa C. M., Standaert D. G., Young A. B. and Penney J. B. Jr. (1994) Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat. J. Neurosci. 14, 3005-3018.
45. Wigmore M., Abbott A. and Lacey M. (1996) Functional characterisation of mGluRs in ventral midbrain. Neuropharmacology 35, A33.
46. Wüllner U., Testa C. M., Catania M. V., Young A. B. and Penney J. B. (1994) Glutamate receptors in striatum and substantia nigra - effects of medial forebrain bundle lesions. Brain Res. 645, 98-102.
47. Young W. S. III and Kuhar M. J. (1986) Quantitative in situ hybridization and determination of mRNA content. In In Situ Hybridization in Brain (ed. Uhl G. R.), pp. 243-248. Plenum, New York.