Plasmodium falciparum: In vitro activity of sulfadoxine and dapsone in field isolates from Kenya: Point mutations in dihydropteroate synthase may not be the only determinants in sulfa resistance

Experimental Parasitology

Volumn 101, Issue 2-3, 2002, Pages 90-96

  Mberu, Edward K ^a,b   Nzila, Alexis M ^a,c   Nduati, Eunice ^a   Ross, Amanda ^a   Monks, Stephanie M ^b   Kokwaro, Gilbert O ^a,c   Watkins, William M ^a,c   Sibley, Carol Hopkins ^b  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Antifolate; Apicomplexa; DHPS; Drug resistance; Malaria

Indexed keywords

DAPSONE; DIHYDROPTEROATE SYNTHASE; FOLIC ACID; SULFADOXINE;

ALLELE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; CHEMOSENSITIVITY; CODON; CONTROLLED STUDY; CORRELATION ANALYSIS; CULTURE MEDIUM; DRUG ACTIVITY; GENOTYPE; HUMAN; IC 50; IN VITRO STUDY; INFANT; KENYA; MALARIA FALCIPARUM; NONHUMAN; PLASMODIUM FALCIPARUM; POINT MUTATION; PRESCHOOL CHILD; PRIORITY JOURNAL; WILD TYPE;

ALLELES; ANIMALS; ANTIMALARIALS; CHILD; CHILD, PRESCHOOL; DAPSONE; DIHYDROPTEROATE SYNTHASE; DNA, PROTOZOAN; DRUG RESISTANCE; GENOTYPE; HUMANS; INFANT; KENYA; MALARIA, FALCIPARUM; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; POINT MUTATION; SULFADOXINE; TETRAHYDROFOLATE DEHYDROGENASE;

APICOMPLEXA; PLASMODIUM FALCIPARUM;

EID: 0036628341     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4894(02)00108-X     Document Type: Article

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