Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria

EMBO Journal

Volumn 17, Issue 14, 1998, Pages 3807-3815

  Triglia, Tony ^a   Wang, Ping ^b   Sims, Paul F G ^b   Hyde, John E ^b   Cowman, Alan F ^a  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Drug resistance; Fansidar; Malaria; Sulfadoxine; Transfection

Indexed keywords

ALANINE; DIHYDROPTEROATE SYNTHASE; GLYCINE; SULFADOXINE;

ALLELE; AMINO ACID SEQUENCE; ARTICLE; CHROMOSOME 8; CONTROLLED STUDY; GENE LOCUS; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC RECOMBINATION; GENETIC TRANSFECTION; MALARIA; NONHUMAN; PHENOTYPE; PLASMODIUM; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALLELES; ANIMALS; ANTIMALARIALS; DIHYDROPTEROATE SYNTHASE; DNA, PROTOZOAN; DRUG RESISTANCE; GENES, PROTOZOAN; MUTAGENESIS; MUTATION; PLASMODIUM FALCIPARUM; POLYPLOIDY; RECOMBINATION, GENETIC; RNA, MESSENGER; RNA, PROTOZOAN; SULFADOXINE;

EID: 0032527779     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.14.3807     Document Type: Article

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