Macrophage-induced inhibition of nitric oxide production in primary rat hepatocyte cultures via prostaglandin E2 release

Hepatology

Volumn 28, Issue 5, 1998, Pages 1300-1308

  Griffon, Bénédicte ^a   Cillard, Josiane ^a   Chevanne, Martine ^a   Morel, Isabelle ^a   Cillard, Pierre ^a   Sergent, Odile ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GROWTH FACTOR; INDOMETACIN; IRON COMPLEX; NITRIC OXIDE; PROSTAGLANDIN E2; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; KUPFFER CELL; LIVER CELL; LIVER INJURY; MACROPHAGE FUNCTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; PROSTAGLANDIN RELEASE; RAT; ULTRAFILTRATION;

EID: 0031725345     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510280519     Document Type: Article

References (19)

1. Laskin DL, Pilaro AM. Potential role of activated macrophages in acetaminophen hepatotoxicity. I. Isolation and characterization of activated macrophages from rat liver. Toxicol Appl Toxicol 1986;86:204-215.
2. Laskin DL. Potential role of activated macrophages in chemical and drug induced liver injury. In: Wisse E, Knook DL, Decker K, eds. Cells of the Hepatic Sinusoid. Vol. 1. Amsterdam: Kupffer Cell Foundation, 1989:284-287.
3. Laskin DL. Nonparenchymal cells and hepatotoxicity. Semin Liver Dis 1990;10:293-304.
4. Shiratori Y, Tanaka M, Hai K, Kawase T, Shiina S, Sugimoto T. Role of endotoxin-responsive macrophages in hepatic injury. HEPATOLOGY 1990;11:183-192.
5. Przybocki JM, Reuhl KR, Thurman RG, Kauffman C. Involvement of nonparenchymal cells in oxygen dependent hepatic injury by allyl alcohol. Toxicol Appl Pharmacol 1992;115:57-63.
6. Mac Donald JR, Beckstead JH, Smuckler EA. An ultrastructural and histochemical study of the prominent inflammatory response in D(+)-galactosamine hepatotoxicity. Br J Exp Pathol 1987;68:189-199.
7. Geerts A, Schellinck P, Bouwens L, Wisse E. Cell population kinetics of Kupffer cells during the onset of fibrosis in rat liver by chronic carbon tetrachloride administration. J Hepatol 1988;6:50-56.
8. Boitnott JK, Maddrey WC. Alcoholic liver disease: I. Inter-relationships among histologie features and histologic effects of prednisolone therapy. HEPATOLOGY 1981;1:599-612.
9. Nolan JP, Camara DS. Intestinal endotoxins as cofactors in the liver injury. Immunol Invest 1989;18:325-337.
10. Lind RC, Gandolfi AJ, Sipes IG, Brown BR. The involvement of endotoxin in halothane-associated liver injury. Anesthesiology 1984;61:544-550.
11. Freudenberg MA, Keppler D, Galanos C. Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin. Infect Immun 1986;51:891-895.
12. Bhagwandeen BS, Apte M, Manwarring L, Dickeson J. Endotoxin induced hepatic necrosis in rats on an alcohol diet. J Pathol 1987;151:47-53.
13. Wang WW, Jenkinson C, Griscavage JM, Kern RM, Arabolos NS, Byrns RE, Cederbaum SD, et al. Co-induction of arginase and nitric oxide symhase in murine macrophages activated by lypopolysaccharide. Biochem Biophys Res Commun 1995;210:1009-1016.
14. Curran RD, Billiar TR, Stuehr DJ, Hoffmann K, Simmons RL. Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells. J Exp Med 1989;170:1769-1774.
15. Geller DA, Nussler AK, Di Silvio M, Lowenstein CJ, Shapiro RA, Wang SC, Simmons RL, et al. Cytokines, endotoxin and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. Proc Natl Acad Sci U S A 1993;90:522-526.
16. Harbrecht BG, Billiar TR, Stadler J, Demetris AJ, Ochoa J, Curran RD, Simmons RL. Inhibition of NO synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen radical-mediated hepatic injury. J Leukoc Biol 1992;52:390-394.
17. Harbrecht BG, Billiar TR, Stadler J, Demetris AJ, Ochoa JB, Curran RD, Simmons RL. Nitric oxide synthesis serves to reduces hepatic damage during acute murine endotoxemia. Crit Care Med 1992;20:1568-1574.
18. G-monomethyl-L-arginine inhibits endotoxin-induced nitrite/nitrate biosynthesis while promoting hepatic damage. J Leukoc Biol 1990;48:565-569.
19. Chamulitrat W, Jordan SJ, Masson RP. Nitric oxide production during endotoxic shock in carbon tetrachloride-treated rats. Mol Pharmacol 1994;46:391-397.