RNA polymerase II complexes in the very early phase of transcription are not susceptible to TFIIS-induced exonucleolytic cleavage

Nucleic Acids Research

Volumn 30, Issue 11, 2002, Pages 2290-2298

  Sijbrandi, Robert ^a,b   Fiedler, Ulrike ^a,c   Timmers, H Th Marc ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR; GUANOSINE TRIPHOSPHATE; RIBONUCLEOTIDE; RNA POLYMERASE II;

ADENOVIRUS; ARTICLE; CONTROLLED STUDY; DNA HYBRIDIZATION; ENZYME STRUCTURE; GENE CONSTRUCT; MOLECULAR MODEL; PRIORITY JOURNAL; PROMOTER REGION; RNA CLEAVAGE; RNA HYBRIDIZATION; RNA TRANSCRIPTION;

ADENOVIRIDAE;

EID: 0036606767     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/30.11.2290     Document Type: Article

References (38)

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5. Three transitions in the RNA polymerase II-transcription complex during initiation
6. Translocation after synthesis of a four-nucleotide RNA commits RNA polymerase II to promoter escape
7. Translocation and transcriptional arrest during transcript elongation by RNA polymerase II
8. Analysis of the open region of RNA polymerase II transcription complexes in the early phase of elongation
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10. Transcription elongation factor SII
11. Control of elongation by RNA polymerase II
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13. Genetic interaction between transcription elongation factor TFIIS and RNA polymerase II
14. The Rpb6 subunit of fission yeast RNA polymerase II is a contact target of the transcription elongation factor TFIIS
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16. Structure of a conserved domain common to the transcription factors TFIIS, elongin A and CRSP70
17. Cleavage of the nascent transcript induced by TFIIS is insufficient to promote read-through of intrinsic blocks to elongation by RNA polymerase II
18. Structure-function relationship of yeast S-II in terms of stimulation of RNA polymerase II, arrest relief and suppression of 6-azauracil sensitivity
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25. Structural basis of transcription: RNA polymerase at 2.8 Å resolution
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27. Transcription initiation by RNA polymerase II does not require hydrolysis of the β-γ phosphoanhydride bond of ATP
28. The requirement for the basal transcription factor IIE is determined by the helical stability of promoter DNA
29. Opening of an RNA polymerase II promoter occurs in two distinct steps and requires the basal transcription factors IIE and IIH
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31. The mammalian TFIID protein is present in two functionally distinct complexes
32. Protein-nucleic acid interactions in transcription: A molecular analysis
33. Strong natural pausing by RNA polymerase II within 10 bases of transcription start may result in repeated slippage and reextension of the nascent RNA
34. Determination of sequences at the capped 5′ ends of polyoma virus early region transcripts synthesizes in vivo and in vitro demonstrates an unusual microheterogeneity
35. Initially transcribed sequences strongly affect the extent of abortive initiation by RNA polymerase II
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