Analysis of the open region of RNA polymerase II transcription complexes in the early phase of elongation

Nucleic Acids Research

Volumn 29, Issue 13, 2001, Pages 2706-2714

  Fiedler, Ulrike ^a   Timmers, H Th Marc ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b Institute for Molecular Oncology   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PERMANGANATE POTASSIUM; RNA POLYMERASE II; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TFIIS; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA FOOTPRINTING; PRIORITY JOURNAL; RNA STRUCTURE; RNA SYNTHESIS;

EID: 0035394528     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.13.2706     Document Type: Article

References (47)

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3. Common themes in assembly and function of eukaryotic transcription complexes
4. Peeling by binding or twisting by cranking: Models for promoter opening and transcription initiation by RNA polymerase II
5. Architecture of RNA polymerase II and implications for the transcription mechanism
6. Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 angstrom resolution
7. General initiation factors for RNA polymerase II
8. The general transcription factors of RNA polymerase II
9. The role of general initiation factors in transcription by RNA polymerase II
10. Mechanism of RNA polymerase II-specific initiation of transcription in vitro: ATP requirement and uncapped runoff transcripts
11. Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II
12. Transcription initiation by RNA polymerase II does not require hydrolysis of the β-γ phosphoanhydride bond of ATP
13. Ten years of TFIIH
14. The multiple roles of transcription/repair factor TFIIH
15. Polymerase II promoter activation: Closed complex formation and ATP-driven start site opening
16. Opening of an RNA polymerase II promoter occurs in two distinct steps and requires the basal transcription factors IIE and IIH
17. Reconstitution of the transcription factor TFIIH: Assignment of function for the three enzymatic subunits, XPB, XPD and cdk7
18. TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair
19. Mechanism of ATP-dependent promoter melting by transcription factor IIH
20. A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes
21. Promoter proximal stalling results from the inability to recruit transcription factor IIH to the transcription complex and is a regulated event
22. Distinct roles for helicases of TFIIH in transcript initiation and promoter escape
23. Requirement for TFIIH kinase activity in transcription by RNA polymerase II
24. A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription
25. Association of Cdk-activating kinase subunits with transcription factor TFIIH
26. A three-step pathway of transcription initiation leading to promoter clearance at an activated RNA polymerase II promoter
27. Interplay of positive and negative effectors in function of the C-terminal repeat domain of RNA polymerase II
28. Recycling of the general transcription factors during RNA polymerase II transcription
29. Repression of basal transcription by HMG2 is counterparted by TFIIH-associated factors in an ATP-dependent process
30. Analysis of open complex formation during RNA polymerase II transcription initiation using heteroduplex templates and potassium permanganate probing
31. Structural changes in the RNA polymerase II transcription complex during transition from initiation to elongation
32. Discontinuous mechanism of transcription elongation
33. Structure of RNA and DNA chains in paused transcription complexes containing Escherichia coli RNA polymerase
34. The requirement for the basal transcription factor IIE is determined by the helical stability of promoter DNA
35. The mammalian TFIID protein is present in two functionally distinct complexes
36. Three transitions in the RNA polymerase II-transcription complex during initiation
37. Basic mechanisms of transcript elongation and its regulation
38. Transcription elongation factor SII
39. Control of elongation by RNA polymerase II
40. Cleavage of the nascent transcript induced by TFIIS is insufficient to promote read-through of intrinsic blocks to elongation by RNA polymerase II
41. Transcriptional fidelity and proofreading by RNA polymerase II
42. Structural analysis of ternary complexes of Escherichia coli RNA polymerase
43. Yeast transcription elongation factor (TFIIS), structure and function
44. The Rpb6 subunit of fission yeast RNA polymerase II is a contact target of the transcription elongation factor TFIIS
45. Translocation of the Escherichia coli transcription complex observed in the registers 11 to 20: "Jumping" of RNA polymerase and assymmetric expansion and contraction of the "transcription bubble"
46. Promoter specificity of basal transcription factors