CD4+ lymphocytopenia in acute infection of Asian macaques by a vaginally transmissible subtype-C, CCR5-tropic simian/human immunodeficiency virus (SHIV)

Journal of Acquired Immune Deficiency Syndromes

Volumn 30, Issue 2, 2002, Pages 133-145

  Chen, Zhiwei ^a   Zhao, Xiuqing ^a   Huang, Yaoxing ^a   Gettie, Agegnehu ^a   Ba, Lei ^a   Blanchard, James ^a   Ho, David D ^a  

^a AARON DIAMOND AIDS RESEARCH CENTER   (United States)

Author keywords

CCR5; CD4+ lymphocytopenia; HIV 1; SHIV; Subtype C; Vaginal transmission

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; VIRUS RNA;

AMINO ACID SEQUENCE; ANIMAL MODEL; ARTICLE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LEUKOCYTE COUNT; LYMPHOCYTOPENIA; MACACA; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; SMALL INTESTINE; T LYMPHOCYTE; VAGINA; VIREMIA; VIRUS ENVELOPE; VIRUS INFECTION; VIRUS LOAD; VIRUS TRANSMISSION;

EID: 0036603368     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-200206010-00001     Document Type: Article

References (68)

1. Serial in vivo passage of HIV-1 infection in Macaca nemestrina
2. Isolation of T-cell tropic HTLV-III-like retrovirus from macaques
3. Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus
4. Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV- III
5. The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus
6. T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
7. Selective infection of human CD4+ cells by simian immunodeficiency virus: Productive infection associated with envelope glycoprotein-induced fusion
8. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
9. The T4 glycoprotein is a cell-surface receptor for the AIDS virus
10. CC CKR5: A RANTES, MIP-1 alpha, MIP-1 beta receptor as a fusion cofactor for macrophage-tropic HIV-1
11. Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry
12. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
13. Identification of a major co-receptor for primary isolates of HIV-1
14. A dual-tropic primary HIV-1 isolate that uses fusin and the beta- chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors
15. + cells is mediated by the chemokine receptor CC- CKR-5
16. Differential utilization of CCR5 by macrophage and T cell tropic simian immunodeficiency virus strains
17. Utilization of C-C chemokine receptor 5 by the envelope glycoproteins of a pathogenic simian immunodeficiency virus, SIVmac239
18. Primary SIVsm isolates use the CCR5 co-receptor from sooty mangabeys naturally infected in West Africa: A comparison of co-receptor usage of primary SIVsm, HIV-2 and SIVmac
19. Change in coreceptor use coreceptor use correlates with disease progression in HIV- 1-infected individuals
20. Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains
21. HIV-1 subtype C syncytium- and non-syncytium-inducing phenotypes and coreceptor usage among Ethiopian patients with AIDS
22. Natural infection of a homozygous Δ24 CCR5 red-capped mangabey with an R2b-tropic simian immunodeficiency virus
23. Expression cloning of new receptors used by simian and human immunodeficiency viruses
24. Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection
25. STRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1
26. Chemokine coreceptor usage by diverse primary isolates of human immunodeficiency virus type 1
27. Changes in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2)
28. Simian-human immunodeficiency virus containing a human immunodeficiency virus type 1 subtype-E envelope gene: Persistent infection, CD4(+) T- cell depletion, and mucosal membrane transmission in macaques
29. +T cells and AIDS in pig-tailed macaques
30. Infection of cynomolgus monkeys with a chimeric HIV-1/SIVmac virus that expresses the HIV-1 envelope glycoproteins
31. Persistent infection of macaques with simian-human immunodeficiency viruses
32. Persistent infection of rhesus macaques with T-cell-line-tropic and macrophage-tropic clones of simian/human immunodeficiency viruses (SHIV)
33. A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys
34. Infection and pathogenicity of chimeric simian-human immunodeficiency viruses in macaques: Determinants of high virus loads and CD4 cell killing
35. Selection for neutralization resistance of the simian/human immunodeficiency virus SHIVSF33A variant in vivo by virtue of sequence changes in the extracellular envelope glycoprotein that modify N-linked glycosylation
36. Distinct pathogenic sequela in rhesus macaques infected with CCR5 or CXCR4 utilizing SHIVs
37. + T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques
38. + T cell loss and AIDS in rhesus macaques
39. + lymphocyte depletion in rhesus monkeys
40. Fatal immunopathogenesis by SIV/HIV-1 (SHIV) containing a variant form of the HIV-1SF33 env gene in juvenile and newborn rhesus macaques
41. Primary subtype C HIV-1 infection in Harare, Zimbabwe
42. Genotypic and phenotypic characterization of HIV-1 patients with primary infection
43. HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain
44. Amino acid substitutions in the human immunodeficiency virus type 1 gp120 V3 loop that change viral tropism also alter physical and functional properties of the virion envelope
45. Selection for specific sequences in the external envelope protein of human immunodeficiency virus type 1 upon primary infection
46. Enhanced infectivity of an R5-tropic simian/human immunodeficiency virus carrying human immunodeficiency virus type 1 subtype C envelope after serial passages in pig-tailed macaques (Macaca nemestrina)
47. Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques
48. Measuring recent thymic emigrants in blood of normal and HIV-1-infected individuals before and after effective therapy
49. + T cell depletion and viral replication in SIV infection
50. Characterization of gut-associated lymphoid tissue (GALT) of normal rhesus macaques
51. Normal T-cell turnover in sooty mangabeys harboring active simian immunodeficiency virus infection
52. A role for carbohydrates in immune evasion in AIDS
53. Phenotypic characteristics of human immunodeficiency virus type 1 subtype C isolates of Ethiopian AIDS patients
54. HIV-1 subtype C in Brazil
55. Genetic variation of HIV type 1 in four World Health Organization-sponsored vaccine evaluation sites: Generation of functional envelope (glycoprotein 160) clones representative of sequence subtypes A, B, C, and E. WHO Network for HIV Isolation and Characterization
56. Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination
57. HIV-1 subtype C in China
58. An infectious DNA clone of HIV type 1 subtype C
59. Molecular cloning and phylogenetic analysis of human immunodeficiency virus type 1 subtype C: A set of 23 full-length clones from Botswana
60. Evidence for differences in MT2 cell tropism according to genetic subtypes of HIV-1: Syncytium-inducing variants seem rare among subtype C HIV-1 viruses
61. Characterization of V3 sequence heterogeneity in subtype C human immunodeficiency virus type 1 isolates from Malawi: Underrepresentation of X4 variants
62. Subtype and sequence analysis of the C2-V3 region of gp120 genes among HIV-1 strains in Sichuan province
63. HIV-1 subtype C epidemic in Ethiopia
64. Characterization of a virtually full-length human immunodeficiency virus type 1 genome of a prevalent intersubtype (C/B′) recombinant strain in china
65. Vpu increases susceptibility of human immunodeficiency virus type 1-infected cells to fas killing
66. Human immunodeficiency virus type 1 Vpu modifies viral cytopathic effect through augmented viral release