NF-κB, inducible nitric oxide synthase and apoptosis by Helicobacter pylori infection

Free Radical Biology and Medicine

Volumn 31, Issue 3, 2001, Pages 355-366

  Lim, Joo Weon ^a   Kim, Hyeyoung ^a   Kim, Kyung Hwan ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Apoptosis; Free radicals; Helicobacter pylori; Inducible nitric oxide synthase; NF B

Indexed keywords

2 AMINO 5,6 DIHYDRO 6 METHYL 4H 1,3 THIAZINE; 3,3 BIS(2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; ANTIOXIDANT; ANTISENSE OLIGONUCLEOTIDE; CATALASE; ENZYME INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LINSIDOMINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; NITRITE; PEROXYNITRITE; PROTEIN SUBUNIT; PYRROLIDINE DITHIOCARBAMATE; THIAZINE DERIVATIVE; UNCLASSIFIED DRUG; 2 AMINO 5,6 DIHYDRO 4H 1,3 THIAZINE; 2-AMINO-5,6-DIHYDRO-4H-1,3-THIAZINE; 3 MORPHOLINO SYDNONIMINE; 3-MORPHOLINO-SYDNONIMINE; ANTISENSE OLIGODEOXYNUCLEOTIDE; DRUG DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; MOLSIDOMINE; NITROSO DERIVATIVE; NOS2A PROTEIN, HUMAN; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMIC ACID; RADIOPROTECTIVE AGENT; THIOCARBAMIC ACID DERIVATIVE;

APOPTOSIS; ARTICLE; BACTERIAL INFECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH ADENOCARCINOMA; TUMOR CELL LINE; BIOSYNTHESIS; CELL LINE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HELICOBACTER INFECTION; METABOLISM; MICROBIOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; STOMACH MUCOSA;

HELICOBACTER PYLORI;

ANTIOXIDANTS; APOPTOSIS; CATALASE; CELL LINE; CELL SURVIVAL; ENZYME INDUCTION; GASTRIC MUCOSA; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MOLSIDOMINE; NF-KAPPA B; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITROSO COMPOUNDS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PYRROLIDINES; RADIATION-PROTECTIVE AGENTS; THIAZINES; THIOCARBAMATES;

EID: 0035430836     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00592-5     Document Type: Article

References (70)

1. Antigenic mimicry between Helicobacter pylori and gastric mucosa in the pathogenesis of body atrophic gastritis
2. Helicobacter pylori infection and the risk of gastric carcinoma
3. Pathogenic mechanisms loading to Helicobacter pylori-induced inflammation
4. Production of reactive oxygen species by gastric cells in association with Helicobacter pylori
5. Activation of the interleukin 6 gene by Mycobacterium tuberculosis or lipopolysaccharide is mediated by nuclear factor NF-IL6 and NF-κB
6. Nitric oxide: Physiology, pathophysiology, and pharmacology
7. Nitric oxide synthases: Roles, tolls, and controls
8. Enhanced gastric nitric oxide synthase activity in duodenal ulcer patients
9. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis
10. Apoptosis in the pathogenesis and treatment of disease
11. Cell death by apoptosis: Basic concepts and disease relevance for the gastroenterologist
12. Nitric oxide-mediated apoptosis in murine peritoneal macrophages
13. Nitric oxide synthase induces macrophage death by apoptosis
14. Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle
15. Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
16. Regulation of gastric epithelial cell growth by Helicobacter pylori: Evidence for a major role of apoptosis
17. Induction of gastric epithelial apoptosis by Helicobacter pylori
18. Helicobacter pylori induces apoptosis in gastric epithelial cells through inducible nitric oxide
19. Induction of caspase-3 and nitric oxide synthase-2 during gastric mucosal inflammatory reaction to Helicobacter pylori lipopolysaccharide
20. Quantitative and qualitative usefulness of rebamipide in eradication regimen of Helicobacter pylori
21. Possibility of chemoprevention by the eradication of Helicobacter pylori: Oxidative DNA damage and apoptosis in H. pylori infection
22. Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene
23. Human inducible nitric oxide synthase gene is transcriptionally regulated by nuclear factor-κB dependent mechanism
24. Function and activation of NF-kappa B in the immune system
25. Structure, regulation and function of NF-κB
26. NF-kappa B: A lesion in family values
27. Hydrogen peroxide and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
28. Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-κB and AP-1
29. Effects of mannitol and dimethylthiourea on Helicobacter pylori-induced IL-8 production in gastric epithelial cells
30. Inhibition of lipid peroxidation, NF-κB activation and IL-8 production by rebamipide in Helicobacter pylori-stimulated gastric epithelial cells
31. Pyrrolidine dithiocarbamate inhibits the production of interleukin-6, interleukin-8, and granulocyte-macrophage colony-stimulating factor by human endothelial cells in response to inflammatory mediators: Modulation of NF-kappa B and AP-1 transcription factors activity
32. Supplementation of N-acetylcysteine inhibits NF-κB activation and protects against alloxan-induced diabetes in CD-1 mice
33. Current concepts in antisense drug design
34. Therapeutic applications of oligonucleotides
35. Effect of phosphorothioate modification of oligodeoxynucleotides on specific protein binding
36. Helicobacter pylori-induced expression of interleukin-8 and cyclooxygenase-2 in AGS gastric epithelial cells: Mediation by nuclear factor-κB
37. Cationic liposomes improve stability and intracellular delivery of antisense oligonucleotides into CaSki cells
38. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
39. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
40. Inhibitors of both nuclear factor-κB and activator protein-1 activation block the neoplastic transformation response
41. Single-step method of RNA isolation by acid guanidine isothiocyanate-phenol-chloroform extraction
42. Molecular structure of the human cytoplasmic β-actin gene: Interspecies homology of sequences in the introns
43. A fluorometric assay for the measurement of nitrite in biological samples
44. An essential role for nuclear factor kappa B in preventing TNF-α-induced dell death in prostate cancer cells
45. Involvement of platelet-activating factor in cell death induced under ischemia/postischemia-like conditions in an immortalized hypocampal cell line
46. Helicobacter pylori infection activates NF-κB in gastric epithelial cells
47. H. pylori activates NF-κB through a signaling pathway involving IκB kinases NF-κB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells
48. Expression of nuclear factor-κB in Helicobacter pylori-infected gastric mucosa detected with southwestern histochemistry
49. Activation of NF-κB by the respiratory burst of macrophages
50. Silica-induced nuclear factor-κB activation: Involvement of reactive oxygen species and protein tyrosine kinase activation
51. Helicobacter pylori extract stimulates inflammatory nitric oxide production
52. Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line
53. Inducible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: Effect of antibiotics and antioxidants
54. Rate of chain breakage at apurinic site in double stranded desoxyribonucleic acid
55. DNA damage and mutation in human cells exposed to nitric oxide in vitro
56. Nitric oxide induces apoptosis in mouse thymocytes
57. Cytokines and nitric oxide in islet inflammation and diabetes
58. IL-1β-induced apoptosis in rat gastric enterochromaffin-like cells is mediated by iNOS, NF-κB, and Bax protein
59. Macrophage triggering with cecropin A and melittin-derived peptides induces type II nitric oxide synthase expression
60. NF-κB activation of p53. A potential mechanism for suppressing cell growth in response to stress
61. c-Rel arrests the proliferation of HeLa cells and affects critical regulators of the G1/S-phase transition
62. Neuroprotection by aspirin and sodium salicylate through blockade of NF-κB activation
63. Induction of apoptosis in murine clonal osteoblasts expressed by human T-cell leukemia virus type I tax by NF-κB and TNF-α
64. Ceramide-induced nuclear translocation of NF-κB is a potential mediator of the apoptotic response to TNF-α in murine clonal osteoblasts
65. Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor κB (NF-κB) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes
66. An essential role for NF-κB in preventing TNF-α-induced cell death
67. TNF-α and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
68. Suppression of TNF-α-induced apoptosis by NF-κB
69. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death