The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor: Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit

European Journal of Biochemistry

Volumn 237, Issue 2, 1996, Pages 393-398

  Chevrier, Bernard ^a   D'Orchymont, Hugues ^b   Schalk, Céline ^b   Tarnus, Céline ^b   Moras, Dino ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b SANOFI   (France)

Author keywords

Exopeptidase; Inhibitor; X ray structure; Zinc enzyme

Indexed keywords

4 IODOPHENYLALANINE HYDROXAMATE; AMINOPEPTIDASE; ENZYME INHIBITOR; HYDROXAMIC ACID DERIVATIVE; PEPTIDASE; UNCLASSIFIED DRUG;

AEROMONAS; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME BINDING; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

AEROMONAS; AMINO ACID SEQUENCE; AMINOPEPTIDASES; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; GLUTAMIC ACID; HYDROXAMIC ACIDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHENYLALANINE; PROTEIN CONFORMATION; ZINC;

EID: 0029960042     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.0393k.x     Document Type: Article

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