Directionality and processivity of molecular motors

Current Opinion in Cell Biology

Volumn 14, Issue 1, 2002, Pages 50-57

  Higuchi, Hideo ^a   Endow, Sharyn A ^b  

^a TOHOKU UNIVERSITY   (Japan)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; KINESIN; MOLECULAR MOTOR; MYOSIN;

BINDING AFFINITY; CONFORMATIONAL TRANSITION; CYTOSKELETON; ELECTRON MICROSCOPY; HYDROLYSIS; MODEL; MOLECULAR DYNAMICS; MUTANT; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW;

EID: 0036469070     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(01)00293-9     Document Type: Review

References (48)

1. Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice
2. Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein
3. Myosin VI is an actin-based motor that moves backwards
4. The core of the motor domain determines the direction of myosin movement
5. Role of the kinesin neck linker and catalytic core in microtubule-based motility
6. Reversal in the direction of movement of a molecular motor
7. The directional preference of kinesin motors is specified by an element outside of the motor catalytic domain
8. Determinants of kinesin motor polarity
9. A mutant of the motor protein kinesin that moves in both directions on microtubules
10. Kinesin follows the microtubule's protofilament axis
11. The Drosophila claret segregation protein is a minus-end directed motor molecule
12. Centrosome and spindle function of the Drosophila Ncd microtubule motor visualized in live embryos using Ncd-GFP fusion proteins
13. Spindle dynamics during meiosis in Drosophila oocytes
14. A processive single-headed motor: Kinesin superfamily protein KIF1A
15. Mechanism of the single-headed processivity: Diffusional anchoring between the K-loop of kinesin and the C terminus of tubulin
16. An ATPase with properties expected for the organelle motor of the giant amoeba, Reticulomyxa
17. Dynein arms are oscillating force generators
18. Stochastic simulation of processive and oscillatory sliding using a two-headed model for axonemal dynein
19. Movement of microtubules by single kinesin molecules
20. Direct observation of kinesin stepping by optical trapping interferometry
21. Mechanics of single kinesin molecules measured by optical trapping nanometry
22. Myosin-V is a processive actin-based motor
23. Inner-arm dynein c of Chlamydomonas flagella is a single-headed processive motor
24. Processive movement of single 22S dynein molecules occurs only at low ATP concentrations
25. Single cytoplasmic dynein molecule movements: Characterization and comparison with kinesin
26. Dynactin increases the processivity of the cytoplasmic dynein motor
27. Two-headed binding of a processive myosin to F-actin
28. The motor protein myosin-I produces its working stroke in two steps
29. Substeps within the 8-nm step of the ATPase cycle of single kinesin molecules
30. A structural change in the kinesin motor protein that drives motility
31. Force production by single kinesin motors
32. A new look at the microtubule binding patterns of dimeric kinesins
33. Nucleotide-dependent single- to double-headed binding of kinesin
34. Kinetics processivity and the direction of motion of Ncd
35. Working strokes by single molecules of the kinesin-related microtubule motor ncd
36. Switch-based mechanism of kinesin motors
37. Single molecule analysis of the actomyosin motor
38. A single myosin head moves along an actin filament with regular steps of 5.3 nanometres
39. Molecular motors: Structural adaptations to cellular functions
40. Orientation dependence of displacements by a single one-headed myosin relative to the actin filament
41. The way things move: Looking under the hood of molecular motors
42. Kinesin has three nucleotide-dependent conformations. Implications for strain-dependent release
43. A FRET-based sensor reveals large ATP hydrolysis-induced conformational changes and three distinct states of the molecular motor myosin
44. Three conformational states of scallop myosin S1
45. Atomic structure of scallop myosin subfragment S1 complexed with MgADP: A novel conformation of the myosin head
46. The crystal structure of dimeric kinesin and implications for microtubule-dependent motility
47. Direction determination in the minus-end-directed kinesin motor ncd