메뉴 건너뛰기




Volumn 20, Issue 3, 2002, Pages 656-664

Phase II study of troxacitabine, a novel dioxolane nucleoside analog, in patients with refractory leukemia

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; 5 AZA 2' DEOXYCYTIDINE; ALPHA INTERFERON; BUSULFAN; CLADRIBINE; CLOFARABINE; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DEOXYCYTIDINE; DEXAMETHASONE; ETOPOSIDE; FLUDARABINE; HOMOHARRINGTONINE; HYDROXYUREA; IDARUBICIN; IMATINIB; METHOTREXATE; MITOXANTRONE; NUCLEOSIDE ANALOG; TALLIMUSTINE; THYMOCYTE ANTIBODY; TIOGUANINE; TOPOTECAN; TROXACITABINE; UNCLASSIFIED DRUG; VINCRISTINE;

EID: 0036467689     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.20.3.656     Document Type: Article
Times cited : (73)

References (43)
  • 1
    • 0033560841 scopus 로고    scopus 로고
    • Randomized phase II study of fludarabine + cytosine arabinoside + idarubicin ± all-trans retinoic acid ± granulocyte colony-stimulating factor in poor prognosis newly diagnosed acute myeloid leukemia and myelodysplastic syndrome
    • (1999) Blood , vol.93 , pp. 2478-2484
    • Estey, E.H.1    Thall, P.F.2    Pierce, S.3
  • 3
    • 0030042611 scopus 로고    scopus 로고
    • Chlorodeoxyadenosine and arabinosylcytosine in patients with acute myelogenous leukemia: Pharmacokinetic, pharmacodynamic, and molecular interactions
    • (1996) Blood , vol.87 , pp. 256-264
    • Gandhi, V.1    Estey, E.2    Keating, M.J.3
  • 4
    • 0029744389 scopus 로고    scopus 로고
    • Clinical and laboratory studies of 2-chlorodeoxyadenosine ± cytosine arabinoside for relapsed or refractory acute myelogenous leukemia in adults
    • (1996) Leukemia , vol.10 , pp. 1563-1569
    • Kornblau, S.M.1    Gandhi, V.2    Andreeff, H.M.3
  • 5
    • 0029063384 scopus 로고
    • Anti-human immunodeficiency virus and anti- hepatitis-B virus activities and toxicities of the enantiomers of 2′-deoxy-3′-oxa-4′-thiocytidine and their 5-fluoro analogues in vitro
    • (1995) J Med Chem , vol.38 , pp. 1-4
    • Mansour, T.S.1    Jin, H.2    Wang, W.3
  • 9
    • 0028982940 scopus 로고
    • Anticancer activity of beta-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration
    • (1995) Cancer Res , vol.55 , pp. 3008-3011
    • Grove, K.L.1    Guo, X.2    Liu, S.H.3
  • 10
    • 0029836284 scopus 로고    scopus 로고
    • Uptake and metabolism of the new anticancer compound beta-L-(-)-dioxolane-cytidine in human prostate carcinoma DU- 145 cells
    • (1996) Cancer Res , vol.56 , pp. 4187-4191
    • Grove, K.L.1    Cheng, Y.C.2
  • 11
    • 0030775136 scopus 로고    scopus 로고
    • Potent antitumor activity of a novel nucleoside analogue, BCH-4556 (beta-L-dioxolane-cytidine), in human renal cell carcinoma xenograft tumor models
    • (1997) Cancer Res , vol.57 , pp. 4803-4810
    • Kadhim, S.A.1    Bowlin, T.L.2    Waud, W.R.3
  • 14
    • 0029088833 scopus 로고
    • L- and D-Enandomers of 2′,3′-dideoxycytidine 5′-triphosphate analogs as substrates for human DNA polymerases: Implications for the mechanism of toxicity
    • (1995) J Biol Chem , vol.270 , pp. 23055-23059
    • Kukhanova, M.1    Liu, S.H.2    Mozzherin, D.3
  • 15
    • 0034613195 scopus 로고    scopus 로고
    • A novel action of human apurinic/apyrimidinic endonuclease: Excision of L-configuration deoxyribonucleoside analogs from the 3' termini of DNA
    • (2000) J Biol Chem , vol.275 , pp. 31009-31015
    • Chou, K.M.1    Kukhanova, M.2    Cheng, Y.C.3
  • 19
    • 0027431843 scopus 로고
    • The biochemical basis for the differential anti-human immunodeficiency virus activity of two cis enantiomers of 2′,3′-dideoxy-3′-thiacytidine
    • (1993) J Biol Chem , vol.268 , pp. 23234-23238
    • Skalski, V.1    Chang, C.N.2    Dutschman, G.3
  • 21
    • 0033538461 scopus 로고    scopus 로고
    • Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3′→5′ exonucleases
    • (1999) J Biol Chem , vol.274 , pp. 19655-19660
    • Mazur, D.J.1    Perrino, F.W.2
  • 23
    • 0025115792 scopus 로고
    • Concordant changes of pyrimidine metabolism in blasts of two cases of acute myeloid leukemia after repeated treatment with ara-C in vivo
    • (1990) Leukemia , vol.4 , pp. 761-765
    • Chiba, P.1    Tihan, T.2    Szekeres, T.3
  • 30
    • 0033214796 scopus 로고    scopus 로고
    • Combination therapy with methotrexate, vincristine, polyethylene-glycol conjugated-asparaginase, and prednisone in the treatment of patients with refractory or recurrent acute lymphoblastic leukemia
    • (1999) Cancer , vol.86 , pp. 1203-1209
    • Aguayo, A.1    Cortes, J.2    Thomas, D.3
  • 31
    • 0033214233 scopus 로고    scopus 로고
    • Primary refractory and relapsed adult acute lymphoblastic leukemia: Characteristics, treatment results, and prognosis with salvage therapy
    • (1999) Cancer , vol.86 , pp. 1216-1230
    • Thomas, D.A.1    Kantarjian, H.2    Smith, T.L.3
  • 33
    • 0033572876 scopus 로고    scopus 로고
    • Chronic myelogenous leukemia in nonlymphoid blastic phase: Analysis of the results of first salvage therapy with three different treatment approaches for 162 patients
    • (1999) Cancer , vol.86 , pp. 2632-2641
    • Sacchi, S.1    Kantarjian, H.M.2    O'Brien, S.3
  • 36
    • 0031417457 scopus 로고    scopus 로고
    • Tallimustine, an effective antileukemic agent in a severe combined immunodeficient mouse model of adult myelogenous leukemia, induces remissions in a phase I study
    • (1997) Clin Cancer Res , vol.3 , pp. 2377-2384
    • Beran, M.1    Jeha, S.2    O'Brien, S.3
  • 41
    • 0000199137 scopus 로고    scopus 로고
    • Clinical efficacy and safety of an abl specific tyrosine kinase inhibitor as targeted therapy for chronic myelogenous leukemia
    • abstr
    • (1999) Blood , vol.94 , pp. 368
    • Druker, B.J.1    Talpaz, M.2    Resta, D.3
  • 42
    • 0001224617 scopus 로고    scopus 로고
    • Activity of an abl specific tyrosine kinase inhibitor in patients with bcr-abl positive acute leukemias, including chronic myelogenous leukemia in blast crisis
    • abstr
    • (1999) Blood , vol.94 , pp. 697
    • Druker, B.J.1    Kantarjian, H.2    Sawyers, C.3
  • 43
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
    • (2001) N Engl J Med , vol.344 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.