Transfer of the cytidine deaminase cDNA into hematopoietic cells

Leukemia Research

Volumn 23, Issue 11, 1999, Pages 1047-1053

  Flasshove, Michael ^a   Frings, Werner ^a   Schröder, Jan K ^a   Moritz, Thomas ^a   Schütte, Jochen ^a   Seeber, Siegfried ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Cytidine deaminase; Cytosine arabinoside; Drug resistance; Gene therapy; Hematopoiesis; Retroviral vector

Indexed keywords

COMPLEMENTARY DNA; CYTARABINE; CYTIDINE DEAMINASE; KANAMYCIN KINASE; VIRUS VECTOR;

ANIMAL CELL; ANTIBIOTIC RESISTANCE; ARTICLE; CANCER CHEMOTHERAPY; CELL LINE; CLONOGENIC ASSAY; CYTOTOXICITY; DNA TRANSFER; ENZYME ACTIVITY; GENE THERAPY; HEMATOPOIETIC CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

3T3 CELLS; ANIMALS; BASE SEQUENCE; CYTARABINE; CYTIDINE DEAMINASE; DNA PRIMERS; DNA, COMPLEMENTARY; DNA, VIRAL; DRUG RESISTANCE; HEMATOPOIETIC STEM CELLS; MICE; PROMOTER REGIONS (GENETICS); REPETITIVE SEQUENCES, NUCLEIC ACID; RETROVIRIDAE; TRANSDUCTION, GENETIC;

EID: 0032849879     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(99)00128-9     Document Type: Article

References (41)

1. Joyner A., Keller G., Phillips R.A., Bernstein A. Retrovirus transfer of a bacterial gene into mouse haematopoietic progenitor cells. Nature. 305:1983;556.
2. Miller A.D., Eckner R.J., Jolly D.J., Friedmann T., Verma I.M. Expression of a retrovirus encoding human HPRT in mice. Science. 225:1984;630.
3. Sorrentino B.P., Brandt S.J., Bodine D., Gottesman M., Pastan I., Cline A., Nienhuis A.W. Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1. Science. 257:1992;99.
4. Williams D.A., Hsieh K., DeSilva A., Mulligan R.C. Protection of bone marrow transplant recipients from lethal doses of methotrexate by the generation of methotrexate-resistant bone marrow. J. Exp. Med. 166:1987;210.
5. Philip T., Guglielmi C., Hagenbeek A., Somers R., Van der Lelie H., Bron D., Sonneveld P., Gisselbrecht C., Cahn J.Y., Harousseau J.L. et al. Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin's lymphoma. New Engl. J. Med. 333:1995;1540.
6. Peters W.P., Dansey R. New concepts in the treatment of breast cancer using high-dose chemotherapy. Cancer Chemother. Pharmacol. 40 (Suppl.):1997;S88.
7. Bishop J.F., Matthews J.P., Young G.A., Bradstock K., Lowenthal R.M. Intensified induction chemotherapy with high dose cytarabine and etoposide for acute myeloid leukemia: a review and updated results of the Australian Leukemia Study Group. Leuk. Lymphoma. 28:1998;315.
8. Galipeau J., Benaim E., Spencer H.T., Blakley R.L., Sorrentino B.P. A bicistronic retroviral vector for protecting hematopoietic cells against antifolates and P-glycoprotein effluxed drugs. Hum. Gene Ther. 8:1997;1773.
9. Flasshove M., Banerjee D., Mineishi S., Li M.X., Bertino J.R., Moore M.A.S. Ex vivo expansion and selection of human CD34-positive peripheral blood progenitor cells after introduction of a mutated dihydrofolate reductase cDNA via retroviral gene transfer. Blood. 85:1995;566.
10. + umbilical cord blood progenitor cells with a mutated dihydrofolate reductase cDNA. Hum. Gene Ther. 9:1998;63.
11. Li M., Banerjee D., Zhao S.C., Schweitzer B.I., Mineishi S., Gilboa E., Bertino J.R. Development of a retroviral construct containing a human mutated dihydrofolate reductase cDNA for hematopoietic stem cell transduction. Blood. 83:1994;3403.
12. Hock R.A., Miller A.D. Retrovirus-mediated gene transfer and expression of drug resistance genes in human haematopoietic progenitor cells. Nature. 320:1986;275.
13. + cells. Blood. 84:1994;1408.
14. Bertolini F., DeMonte L., Corsini C., Lazzari L., Lauri L., Soligo D., Ward M., Bank A., Malavasi F. Retrovirus-mediated transfer of the multidrug resistance gene into human haemopoietic progenitor cells. Br. J. Haematol. 88:1994;318.
15. Baum C., Hegewisch-Becker S., Eckert H.G., Stocking C., Ostertag W. Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells. J. Virol. 69:1995;7541.
16. Hesdorffer C., Ayello J., Ward M., Kaubisch A., Vahdat L., Balmaceda C., Garrett T., Fetell M., Reiss R., Bank A., Antman K. Phase I trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem cell transplantation. J. Clin Oncol. 16:1998;165.
17. Allay J.A., Dumenco L.L., Koc O.N., Liu L., Gerson S.L. Retroviral transduction and expression of the human alkyltransferase cDNA provides nitrosourea resistance to hematopoietic cells. Blood. 85:1995;3342.
18. Moritz T., Mackay W., Glassner B.J., Williams D.A., Samson L. Retrovirus-mediated expression of a DNA repair protein in bone marrow protects hematopoietic cells from nitrosourea-induced toxicity in vitro and in vivo. Cancer Res. 55:1995;2608.
19. Yusa K., Ohuhara T., Tsukahara S., Tsurua T. Human immunodeficiency virus type 1 induces 1-β-arabinofuranosylcytosine resistance in human H9 cell line. J. Biol. Chem. 267:1992;16848.
20. Steuart C.D., Burke P.J. Cytidine deaminase and the development of resistance to arabinosyl cytosine. Nat. New Biol. 233:1971;109.
21. Kufe D., Spriggs D., Egan E.M., Munroe D. Relationships among ara-CTP pools, formation of (ara-C)DNA, and cytotoxicity of human leukemic cells. Blood. 64:1984;54.
22. Kuhn K., Bertling W.M., Emmrich F. Cloning of a functional cDNA for human cytidine deaminase (CDD) and its use as a marker of monocyte/macrophage differentiation. Biochem. Biophys. Res. Commun. 190:1993;1.
23. Laliberte J., Momparler R.L. Human cytidine deaminase: purification of enzyme, cloning, and expression of its complementary DNA. Cancer Res. 54:1994;5401.
24. Schröder J.K., Kirch C., Flasshove M., Kalweit H., Seidelmann M., Hilger R., Seeber S., Schütte J. Constitutive overexpression of the cytidine deaminase gene confers resistance to cytosine arabinoside in vitro. Leukemia. 10:1996;1919.
25. Neff T., Blau C.A. Forced expression of cytidine deaminase confers resistance to cytosine arabinoside and gemcitabine. Exp. Hematol. 24:1996;1340.
26. Momparler R.L., Eliopoulos N., Bovenzi V., Letourneau S., Greenbaum M., Cournoyer D. Resistance to cytosine arabinoside by retrovirally mediated gene transfer of human cytidine deaminase into murine fibroblast and hematopoietic cells. Cancer Gene Ther. 3:1996;331.
27. Gansbacher B., Bannerji R., Daniels B., Zier K., Cronin K., Gilboa E. Retroviral vector-mediated gamma-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity. Cancer Res. 50:1990;7820.
28. Hantzopoulos P.A., Sullenger B.A., Ungers G., Gilboa E. Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector. Proc. Natl. Acad. Sci. USA. 86:1989;3519.
29. Markowitz D., Goff S., Bank A. A safe packaging line for gene transfer: separating viral genes on two different plasmids. J. Virol. 62:1988;1120.
30. Li M., Hantzopoulos P.A., Banerjee D., Zhao S.C., Schweitzer B.I., Gilboa E., Bertino J.R. Comparison of the expression of a mutant dihydrofolate reductase under control of different internal promoters in retroviral vectors. Hum. Gene Ther. 3:1992;381.
31. Higuchi R. Rapid, efficient DNA extraction for PCR from cells or blood. Amplifications. 2:1989;1.
32. Anderson W.F. Human gene therapy. Science. 256:1992;808.
33. Brenner M.K., Rill D.R., Holladay M.S., Heslop H.E., Moen R.C., Buschle M., Krance R.A., Santana V.M., Anderson W.F., Ihle J.N. Gene marking to determine whether autologous marrow infusion restores long-term hematopoiesis in cancer patients. Lancet. 342:1993;1134.
34. Donahue R.E., Kessler S.W., Bodine D., McDonagh K., Dunbar C., Goodman S., Agricola B., Byrne E., Raffeld M., Moen R., Bacher J., Zsebo K.M., Nienhuis A.W. Helper virus induced T-cell lymphoma in nonhuman primates after retroviral mediated gene transfer. J. Exp. Med. 176:1992;1125.
35. Bunting K.D., Galipeau J., Topham D., Benaim E., Sorrentino B.P. Transduction of murine bone marrow cells with an MDR1 vector enables ex vivo stem cell expansion, but these expanded grafts cause a myeloproliferative syndrome in transplanted mice. Blood. 92:1998;2269.
36. Gran C., Boyum A., Johansen R.F., Lovhaug D., Seeberg E.C. Growth inhibition of granulocyte-macrophage colony-forming cells by human cytidine deaminase requires the catalytic function of the protein. Blood. 91:1998;4127.
37. Capizzi R.L., White J.C., Powell B.L., Perrino F. Effect of dose on the pharmacokinetic and pharmacodynamic effects of cytarabine. Semin. Hematol. 28:1991;54.
38. + hematopoietic cells. Hum. Gene Ther. 8:1997;2193.
39. Eliopoulos N., Bovenzi V., Le N.L.O., Momparler L.F., Greenbaum M., Letourneau S., Cournoyer D., Momparler R.L. Retroviral transfer and long-term expression of human cytidine deaminase cDNA in hematopoietic cells following transplantation in mice. Gene Ther. 5:1998;1545.
40. Beausejour C.M., Le N.L., Letourneau S., Cournoyer D., Momparler R.L. Coexpression of cytidine deaminase and mutant dihydrofolate reductase by a bicistronic retroviral vector confers resistance to cytosine arabinoside and methotrexate. Hum. Gene Ther. 9:1998;2537.
41. Schröder J.K., Seidelmann M., Kirch H.C., Seeber S., Schütte J. Assessment of resistance induction to cytosine arabinoside following transfer and overexpression of the deoxycytidylate deaminase gene in vitro. Leuk. Res. 22:1998;619.