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Volumn 10, Issue 10, 1996, Pages 1563-1569

Clinical and laboratory studies of 2-chlorodeoxyadenosine ± cytosine arabinoside for relapsed or refractory acute myelogenous leukemia in adults

Author keywords

2CdA; Adults; Ara C; Pharmacology; Relapsed AML

Indexed keywords

CLADRIBINE; CYTARABINE;

EID: 0029744389     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (82)

References (32)
  • 1
    • 0027268733 scopus 로고
    • Activity of human DNA polymerase α and β with 2-chloro-2′-deoxyadenosine triphosphate as a substrate and quantitative effects of incorporation on chain extension
    • Chunduru SK, Appleman JR, Blakeley RL. Activity of human DNA polymerase α and β with 2-chloro-2′-deoxyadenosine triphosphate as a substrate and quantitative effects of incorporation on chain extension. Arch Biochem Biophys 1993; 302: 19-30.
    • (1993) Arch Biochem Biophys , vol.302 , pp. 19-30
    • Chunduru, S.K.1    Appleman, J.R.2    Blakeley, R.L.3
  • 2
    • 0025811415 scopus 로고
    • Effects of 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5′-triphosphates
    • Parker WB, Shaddix SC, Chang C-H, White L, Rose LM, Brockman W, Shortnacy AT, Montgomery JA, Secrist JA, Bennett LL Jr. Effects of 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5′-triphosphates. Cancer Res 1991; 51: 2386-2394.
    • (1991) Cancer Res , vol.51 , pp. 2386-2394
    • Parker, W.B.1    Shaddix, S.C.2    Chang, C.-H.3    White, L.4    Rose, L.M.5    Brockman, W.6    Shortnacy, A.T.7    Montgomery, J.A.8    Secrist, J.A.9    Bennett Jr., L.L.10
  • 4
    • 0020612685 scopus 로고
    • Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes
    • Carson DA, Wasson B, Taetle R, Yu A. Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes. Blood 1983; 62: 737-743.
    • (1983) Blood , vol.62 , pp. 737-743
    • Carson, D.A.1    Wasson, B.2    Taetle, R.3    Yu, A.4
  • 6
    • 0026803021 scopus 로고
    • A single cycle of 2-chlorodeoxyadenosine results in complete remission in the majority of patients with hairy cell leukemia
    • Tallman MS, Hakimian D, Variakojis D, Koslow D, Sisney GA, Rademaker AW, Rose E, Kaul K. A single cycle of 2-chlorodeoxyadenosine results in complete remission in the majority of patients with hairy cell leukemia. Blood 1992; 80: 2203-2209.
    • (1992) Blood , vol.80 , pp. 2203-2209
    • Tallman, M.S.1    Hakimian, D.2    Variakojis, D.3    Koslow, D.4    Sisney, G.A.5    Rademaker, A.W.6    Rose, E.7    Kaul, K.8
  • 7
    • 0026675806 scopus 로고
    • Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine
    • Juliusson G, Elmhorn-Rosenborg A, Liliemark J. Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine. New Engl J Med 1992; 327: 1056-1061.
    • (1992) New Engl J Med , vol.327 , pp. 1056-1061
    • Juliusson, G.1    Elmhorn-Rosenborg, A.2    Liliemark, J.3
  • 9
    • 0028219970 scopus 로고
    • 2-Chlorodeoxyadenosine: A newer purine analog active in the treatment of indolent lymphoid malignancies
    • Saven A, Piro LD. 2-Chlorodeoxyadenosine: a newer purine analog active in the treatment of indolent lymphoid malignancies. Ann Intern Med 1994; 120: 784-791.
    • (1994) Ann Intern Med , vol.120 , pp. 784-791
    • Saven, A.1    Piro, L.D.2
  • 11
    • 0028221174 scopus 로고
    • Complete hematologic remissions in chronic-phase Philadelphia-positive, chronic myelogenous leukemia after 2-chlorodeoxyadenosine
    • Saven A, Piro LD, Lemon RH, Figueueroa ML, Kosty M, Ellison DJ, Beutler E. Complete hematologic remissions in chronic-phase Philadelphia-positive, chronic myelogenous leukemia after 2-chlorodeoxyadenosine. Cancer 1994; 73: 2953-2963.
    • (1994) Cancer , vol.73 , pp. 2953-2963
    • Saven, A.1    Piro, L.D.2    Lemon, R.H.3    Figueueroa, M.L.4    Kosty, M.5    Ellison, D.J.6    Beutler, E.7
  • 13
    • 0026536178 scopus 로고
    • 2-Chlorodeoxyadenosine produces a high rate of complete hematologic remission in relapsed acute myeloid leukemia
    • Santana VM, Mirro J Jr, Kearns C, Schell MJ, Crom W, Blakley RL. 2-Chlorodeoxyadenosine produces a high rate of complete hematologic remission in relapsed acute myeloid leukemia. J Clin Oncol 1992; 10: 364-370.
    • (1992) J Clin Oncol , vol.10 , pp. 364-370
    • Santana, V.M.1    Mirro Jr., J.2    Kearns, C.3    Schell, M.J.4    Crom, W.5    Blakley, R.L.6
  • 14
    • 0027932742 scopus 로고
    • Complete hematologic remissions induced by 2-chlorodeoxyadenosine in children with newly diagnosed acute myelogenous leukemia
    • Santana VM, Hurwitz CA, Blakeley RL, Crom WR, Luo X, Roberts M, Ribeiro R, Mahmoud H, Krance RA. Complete hematologic remissions induced by 2-chlorodeoxyadenosine in children with newly diagnosed acute myelogenous leukemia. Blood 1994; 84: 1237-1242.
    • (1994) Blood , vol.84 , pp. 1237-1242
    • Santana, V.M.1    Hurwitz, C.A.2    Blakeley, R.L.3    Crom, W.R.4    Luo, X.5    Roberts, M.6    Ribeiro, R.7    Mahmoud, H.8    Krance, R.A.9
  • 15
    • 0028102950 scopus 로고
    • Therapeutic and neurotoxic effects of 2-chlorodeoxyadenosine in adults with acute myeloid leukemia
    • Vahdat L, Wong EG, Wile MJ, Rosenblum M, Foley KM, Warrell RP Jr. Therapeutic and neurotoxic effects of 2-chlorodeoxyadenosine in adults with acute myeloid leukemia. Blood 1994; 84: 3429-3434.
    • (1994) Blood , vol.84 , pp. 3429-3434
    • Vahdat, L.1    Wong, E.G.2    Wile, M.J.3    Rosenblum, M.4    Foley, K.M.5    Warrell Jr., R.P.6
  • 16
    • 0027450455 scopus 로고
    • Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy
    • Gandhi V, Estey E, Keating MJ, Plunkett W. Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy. J Clin Oncol 1993; 11: 116-124.
    • (1993) J Clin Oncol , vol.11 , pp. 116-124
    • Gandhi, V.1    Estey, E.2    Keating, M.J.3    Plunkett, W.4
  • 17
    • 0026603588 scopus 로고
    • Fludarabine infusion potentiates arabinosylcytosine metabolism in lymphocytes of patients with chronic lymphocytic leukemia
    • Gandhi V, Kemena A, Keating MJ, Plunkett W. Fludarabine infusion potentiates arabinosylcytosine metabolism in lymphocytes of patients with chronic lymphocytic leukemia. Cancer Res 1992; 52: 897-903.
    • (1992) Cancer Res , vol.52 , pp. 897-903
    • Gandhi, V.1    Kemena, A.2    Keating, M.J.3    Plunkett, W.4
  • 18
    • 0028228008 scopus 로고
    • Combination of fludarabine and arabinosylcytosine for treatment of chronic lymphocytic leukemia: Clinical efficacy and modulation of arabinosylcytosine pharmacology
    • Gandhi V, Robertson LE, Keating MJ, Plunkett W. Combination of fludarabine and arabinosylcytosine for treatment of chronic lymphocytic leukemia: clinical efficacy and modulation of arabinosylcytosine pharmacology. Cancer Chemother Pharmacol 1994; 34: 30-36.
    • (1994) Cancer Chemother Pharmacol , vol.34 , pp. 30-36
    • Gandhi, V.1    Robertson, L.E.2    Keating, M.J.3    Plunkett, W.4
  • 20
    • 0023854422 scopus 로고
    • Modulation of arabinosyl nucleoside metabolism by arabinosylnucleotides in human leukemia cells
    • Gandhi V, Plunkett W. Modulation of arabinosyl nucleoside metabolism by arabinosylnucleotides in human leukemia cells. Cancer Res 1988; 48: 329-334.
    • (1988) Cancer Res , vol.48 , pp. 329-334
    • Gandhi, V.1    Plunkett, W.2
  • 21
    • 0030042611 scopus 로고    scopus 로고
    • Chlorodeoxyadenosine and arabinosylcytosine in patients with acute myelogenous leukemia: Pharmacokinetic, pharmacodynamic, and molecular interactions
    • Gandhi V, Estey E, Keating MJ, Chucrallah A, Plunkett W. Chlorodeoxyadenosine and arabinosylcytosine in patients with acute myelogenous leukemia: pharmacokinetic, pharmacodynamic, and molecular interactions. Blood 1996; 87: 256-264.
    • (1996) Blood , vol.87 , pp. 256-264
    • Gandhi, V.1    Estey, E.2    Keating, M.J.3    Chucrallah, A.4    Plunkett, W.5
  • 22
    • 0028171391 scopus 로고
    • Interactions between cladarabine (2-chlorodeoxyadenosine) and standard antileukemic drugs in primary cultures of human tumor cells from patients with acute myelocytic leukemia
    • Kristensen J, Nygren P, Liliemark J, Fridborg H, Killander A, Simonsson B, Oberg G, Larsson R. Interactions between cladarabine (2-chlorodeoxyadenosine) and standard antileukemic drugs in primary cultures of human tumor cells from patients with acute myelocytic leukemia. Leukemia 1994; 8: 1712-1717.
    • (1994) Leukemia , vol.8 , pp. 1712-1717
    • Kristensen, J.1    Nygren, P.2    Liliemark, J.3    Fridborg, H.4    Killander, A.5    Simonsson, B.6    Oberg, G.7    Larsson, R.8
  • 23
    • 0013909023 scopus 로고    scopus 로고
    • Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man
    • Freireich EJ, Gehan EA, Rall DP, Schmidt LH, Skipper HE. Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man. Cancer Chemother Rep 1996; 50: 219-244.
    • (1996) Cancer Chemother Rep , vol.50 , pp. 219-244
    • Freireich, E.J.1    Gehan, E.A.2    Rall, D.P.3    Schmidt, L.H.4    Skipper, H.E.5
  • 24
    • 0023273525 scopus 로고
    • Saturation of 1-β-D-arabinosylcytosine 5′-triphosphate accumulation in leukemic cells during high dose 1-β-D-arabinosylcytosine therapy
    • Plunkett W, Liliemark JO, Adams TM, Nowak B, Estey E, Kantarjian H, Keating MJ. Saturation of 1-β-D-arabinosylcytosine 5′-triphosphate accumulation in leukemic cells during high dose 1-β-D-arabinosylcytosine therapy. Cancer Res 1987; 47: 3005-3011.
    • (1987) Cancer Res , vol.47 , pp. 3005-3011
    • Plunkett, W.1    Liliemark, J.O.2    Adams, T.M.3    Nowak, B.4    Estey, E.5    Kantarjian, H.6    Keating, M.J.7
  • 25
    • 0023356575 scopus 로고
    • Saturation of ara-CTP accumulation during high-dose ara-C therapy. Phamacologic rational for intermediate-dose ara-C
    • Plunkett W, Liliemark JO, Estey E, Keating MJ. Saturation of ara-CTP accumulation during high-dose ara-C therapy. Phamacologic rational for intermediate-dose ara-C. Semin Oncol 1987; 14 (Suppl. 1): 159.
    • (1987) Semin Oncol , vol.14 , Issue.1 SUPPL. , pp. 159
    • Plunkett, W.1    Liliemark, J.O.2    Estey, E.3    Keating, M.J.4
  • 26
    • 0018906892 scopus 로고
    • Quantitation of 1-β-D-arabinofuranosylcytosine 5′-triphosphate in the leukemic cells from bone marrow and peripheral blood of patients receiving 1-β-D-arabinofuranosylcytosine therapy
    • Plunkett W, Hug V, Keating MJ, Chubb S. Quantitation of 1-β-D-arabinofuranosylcytosine 5′-triphosphate in the leukemic cells from bone marrow and peripheral blood of patients receiving 1-β-D-arabinofuranosylcytosine therapy. Cancer Res 1980; 40: 588-591.
    • (1980) Cancer Res , vol.40 , pp. 588-591
    • Plunkett, W.1    Hug, V.2    Keating, M.J.3    Chubb, S.4
  • 27
    • 0027213870 scopus 로고
    • Fludarabine and arabinosylcytosine therapy of refractory and relapsed acute myelogenous leukemia
    • Estey E, Plunkett W, Gandhi V, Rios MB, Kantarjian H, Keating MJ. Fludarabine and arabinosylcytosine therapy of refractory and relapsed acute myelogenous leukemia. Leuk Lymphoma 1993; 9: 343-350.
    • (1993) Leuk Lymphoma , vol.9 , pp. 343-350
    • Estey, E.1    Plunkett, W.2    Gandhi, V.3    Rios, M.B.4    Kantarjian, H.5    Keating, M.J.6
  • 28
    • 0023662662 scopus 로고
    • Separation of 1-β-D-arabinofuranosyl-2-fluoroadenine 5′-triphosphate in human leukemic cells by high performance liquid chromatography
    • Gandhi V, Danhauser L, Plunkett W. Separation of 1-β-D-arabinofuranosyl-2-fluoroadenine 5′-triphosphate in human leukemic cells by high performance liquid chromatography. J Chromatogr 1987; 413: 293-299.
    • (1987) J Chromatogr , vol.413 , pp. 293-299
    • Gandhi, V.1    Danhauser, L.2    Plunkett, W.3
  • 29
    • 0027202144 scopus 로고
    • A Bayesian strategy for screening cancer treatments prior to phase II evaluation
    • Thall PF, Estey E. A Bayesian strategy for screening cancer treatments prior to phase II evaluation. Stat Med 1993; 12: 1197-1211.
    • (1993) Stat Med , vol.12 , pp. 1197-1211
    • Thall, P.F.1    Estey, E.2
  • 30
    • 0028918514 scopus 로고
    • Cellular pharmacokinetics of 2-chloro-2′ deoxyadenosine nucleotides: Comparison of intermittent and continuous intravenous infusion and subcutaneous and oral administration in leukemia patients
    • Liliemark J, Juliusson G. Cellular pharmacokinetics of 2-chloro-2′ deoxyadenosine nucleotides: comparison of intermittent and continuous intravenous infusion and subcutaneous and oral administration in leukemia patients. Clin Cancer Res 1995; 1: 385-390.
    • (1995) Clin Cancer Res , vol.1 , pp. 385-390
    • Liliemark, J.1    Juliusson, G.2
  • 32
    • 0028869006 scopus 로고
    • A phase II study of menogaril (7R-O-methylnogarol) in patients with relapsed/refractory acute myeloid leukemia: A study of the Eastern Cooperative Oncology Group
    • Dutcher JP, Leong T, Makary AZ, Bennett J, Frontiera M, Miller H, Wiernik PH. A phase II study of menogaril (7R-O-methylnogarol) in patients with relapsed/refractory acute myeloid leukemia: a study of the Eastern Cooperative Oncology Group. Leukemia 1995; 9: 1638-1642.
    • (1995) Leukemia , vol.9 , pp. 1638-1642
    • Dutcher, J.P.1    Leong, T.2    Makary, A.Z.3    Bennett, J.4    Frontiera, M.5    Miller, H.6    Wiernik, P.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.