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Volumn 56, Issue 18, 1996, Pages 4187-4191

Uptake and metabolism of the new anticancer compound β-L-(-)-dioxolane- cytidine in human prostate carcinoma DU-145 cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; CYTARABINE; CYTIDINE DERIVATIVE; DIOXOLANE CYTIDINE; DNA FRAGMENT; DRUG METABOLITE; NUCLEOSIDE ANALOG; UNCLASSIFIED DRUG;

EID: 0029836284     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (77)

References (27)
  • 1
    • 0028808367 scopus 로고
    • Use of novel β-L-nucleoside analogs for treatment and prevention of chronic hepatitis B virus and hepatocellular carcinoma
    • Bridges, E. G., and Cheng, Y-C. Use of novel β-L-nucleoside analogs for treatment and prevention of chronic hepatitis B virus and hepatocellular carcinoma. Prog. Liver Dis., 9. 231-45, 1995.
    • (1995) Prog. Liver Dis. , vol.9 , pp. 231-245
    • Bridges, E.G.1    Cheng, Y.-C.2
  • 2
    • 0029028067 scopus 로고
    • Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy
    • Washington DC
    • Larder, B. A., Kemp, S. D., and Harrigan, P. R Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy. Science (Washington DC), 269 696-699, 1995.
    • (1995) Science , vol.269 , pp. 696-699
    • Larder, B.A.1    Kemp, S.D.2    Harrigan, P.R.3
  • 3
    • 0029965190 scopus 로고    scopus 로고
    • Favorable interaction of β-L-(-)-nucleoside analogues with clinically approved anti-HIV nucleoside analogues for the treatment of human immunodeficiency virus
    • Bridges, E G., Dutschman, G. E , Gullen, E. A., and Cheng, Y. C. Favorable interaction of β-L-(-)-nucleoside analogues with clinically approved anti-HIV nucleoside analogues for the treatment of human immunodeficiency virus. Biochem Pharmacol., 51: 753-736, 1996.
    • (1996) Biochem Pharmacol. , vol.51 , pp. 753-1736
    • Bridges, E.G.1    Dutschman, G.E.2    Gullen, E.A.3    Cheng, Y.C.4
  • 4
    • 0028982940 scopus 로고
    • Anti-cancer activity of β-L-(-)-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L-configuration
    • Grove, K. L , Quo, X , Liu, S-H., Gao, Z , Chu, C. K., and Cheng, Y-C. Anti-cancer activity of β-L-(-)-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L-configuration. Cancer Res., 55; 3008-3011, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3008-3011
    • Grove, K.L.1    Quo, X.2    Liu, S.-H.3    Gao, Z.4    Chu, C.K.5    Cheng, Y.-C.6
  • 5
    • 0029088833 scopus 로고
    • L- and D-enantiomers of 2′,3′-dideoxycylidine-5′-triphosphate analogs as substrates for human DNA polymerases
    • Kukhanova, M., Liu, S-H., Mozzherin, D , Lin, T-S., Chu, C. K., and Cheng, Y. C L- and D-enantiomers of 2′,3′-dideoxycylidine-5′-triphosphate analogs as substrates for human DNA polymerases. J. Biol. Chem., 270: 23055-23059, 1995
    • (1995) J. Biol. Chem. , vol.270 , pp. 23055-23059
    • Kukhanova, M.1    Liu, S.-H.2    Mozzherin, D.3    Lin, T.-S.4    Chu, C.K.5    Cheng, Y.C.6
  • 6
    • 0017847558 scopus 로고
    • Transport and metabolism of deoxycytidine and 1-β-D-arabinofuranosylcytosine in cultured Novikoff rat hepatoma cells, relationship to phosphorylation and regulation of triphosphate synthesis
    • Plagemann, P. G. W., Marz, R , and Wohlhuerter, R M. Transport and metabolism of deoxycytidine and 1-β-D-arabinofuranosylcytosine in cultured Novikoff rat hepatoma cells, relationship to phosphorylation and regulation of triphosphate synthesis. Cancer Res., 38: 978-989, 1978.
    • (1978) Cancer Res. , vol.38 , pp. 978-989
    • Plagemann, P.G.W.1    Marz, R.2    Wohlhuerter, R.M.3
  • 7
    • 0021953877 scopus 로고
    • Cytosine arabinoside transport and metabolism in acute leukemia and acute lymphoblastic lymphoma
    • Wiley, J. S., Taupin, J , Jamieson, G P., Snook, M., Sawyer, W H., and Finch, L. R. Cytosine arabinoside transport and metabolism in acute leukemia and acute lymphoblastic lymphoma. J Clin. Invest., 75: 632-642, 1985
    • (1985) J Clin. Invest. , vol.75 , pp. 632-642
    • Wiley, J.S.1    Taupin, J.2    Jamieson, G.P.3    Snook, M.4    Sawyer, W.H.5    Finch, L.R.6
  • 8
    • 0023115207 scopus 로고
    • Membrane transport influences the rate of accumulation of cytosine arabinoside in human leukemic cells
    • White, J C., Rathmell, J P , and Capizzi, R L. Membrane transport influences the rate of accumulation of cytosine arabinoside in human leukemic cells J. Clin. Invest., 79: 380-387, 1987.
    • (1987) J. Clin. Invest. , vol.79 , pp. 380-387
    • White, J.C.1    Rathmell, J.P.2    Capizzi, R.L.3
  • 9
    • 0023783698 scopus 로고
    • Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosyl-cytosine
    • Heinemann, V , Hertel, L. W , Grindey, G. B., and Plunkett, W. Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosyl-cytosine. Cancer Res., 48 4024-4031, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 4024-4031
    • Heinemann, V.1    Hertel, L.W.2    Grindey, G.B.3    Plunkett, W.4
  • 10
    • 0018741351 scopus 로고
    • Correlation between leukemic cell retention of 1-β-D-arabinofuranosylcytosine-5′-triphosphate and response to therapy
    • Rustum, Y. M , and Preisler, H. D. Correlation between leukemic cell retention of 1-β-D-arabinofuranosylcytosine-5′-triphosphate and response to therapy Cancer Res., 39: 42-49, 1979.
    • (1979) Cancer Res. , vol.39 , pp. 42-49
    • Rustum, Y.M.1    Preisler, H.D.2
  • 11
    • 0023935496 scopus 로고
    • Prevention of 1-β-D-arabinofuranosylcytosine toxicity by 4-nitrobenzyl-6-thiomosine or dipyridamole in leukemic cell lines
    • Kubota, M , Takimoto, T., Kitoh, T., Tanizawa, A., Kiriyama, Y , Akiyama, Y., and Mikawa, H. Prevention of 1-β-D-arabinofuranosylcytosine toxicity by 4-nitrobenzyl-6-thiomosine or dipyridamole in leukemic cell lines Anticancer Res., 8: 339-342, 1988
    • (1988) Anticancer Res. , vol.8 , pp. 339-342
    • Kubota, M.1    Takimoto, T.2    Kitoh, T.3    Tanizawa, A.4    Kiriyama, Y.5    Akiyama, Y.6    Mikawa, H.7
  • 13
    • 0027308301 scopus 로고
    • Membrane permeation mechanisms of 2′,3′-dideoxynucleosides
    • Domin, B. A., Mahony, W. B., and Zimmerman, T. P. Membrane permeation mechanisms of 2′,3′-dideoxynucleosides. Biochem. Pharmacol., 46: 725-729, 1993
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 725-729
    • Domin, B.A.1    Mahony, W.B.2    Zimmerman, T.P.3
  • 15
    • 0027175126 scopus 로고
    • BIBW 22, a dipyndamole analogue, acts as a bifunctional modulator on tumor cells by influencing both P-glycoprotein and nucleoside transport
    • Chen, H X., Bamberger, U., Heckel, A., Guo, X., and Cheng, Y-c. BIBW 22, a dipyndamole analogue, acts as a bifunctional modulator on tumor cells by influencing both P-glycoprotein and nucleoside transport. Cancer Res., 53: 1974-1977, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 1974-1977
    • Chen, H.X.1    Bamberger, U.2    Heckel, A.3    Guo, X.4    Cheng, Y.-C.5
  • 16
    • 0021166371 scopus 로고
    • A semiautomated microculture method for investigating exponentially growing carcinoma cells
    • Finlay, G J., Baguley, B. C., and Wilson, W R. A semiautomated microculture method for investigating exponentially growing carcinoma cells. Anal. Biochem., 139: 272-277, 1984.
    • (1984) Anal. Biochem. , vol.139 , pp. 272-277
    • Finlay, G.J.1    Baguley, B.C.2    Wilson, W.R.3
  • 17
    • 0024515139 scopus 로고
    • Sequence-specific inhibition of DNA strand elongation by incorporation of 9-β-D-arabinofuranosyladenine
    • Ohno, Y., Spriggs, D , Matsukage, A , Ohno, T., and Kufe, D. Sequence-specific inhibition of DNA strand elongation by incorporation of 9-β-D-arabinofuranosyladenine. Cancer Res., 49: 2077-2081, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 2077-2081
    • Ohno, Y.1    Spriggs, D.2    Matsukage, A.3    Ohno, T.4    Kufe, D.5
  • 19
    • 0026563976 scopus 로고
    • Biochemical pharmacology of (+) and (-)-2′,3′-dideoxy-3′-thracytidine as anti hepatitis B virus agents
    • Chang, C-N., Skalski, V., Zhou, J. H , and Cheng, Y C. Biochemical pharmacology of (+) and (-)-2′,3′-dideoxy-3′-thracytidine as anti hepatitis B virus agents. J. Biol. Chem , 267: 22414-22420, 1992.
    • (1992) J. Biol. Chem , vol.267 , pp. 22414-22420
    • Chang, C.-N.1    Skalski, V.2    Zhou, J.H.3    Cheng, Y.C.4
  • 20
    • 0028260316 scopus 로고
    • Intracellular metabolism of (-)- and (+)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine in HepG2 derivative 22.15 (subclone P5A) cells
    • Paff, M. T , Auerett, D R., Prus, K. L., Miller, W. H., and Nelson, D J. Intracellular metabolism of (-)- and (+)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine in HepG2 derivative 22.15 (subclone P5A) cells. Antimicrob. Agents Chem., 38: 1230-1238, 1994.
    • (1994) Antimicrob. Agents Chem. , vol.38 , pp. 1230-1238
    • Paff, M.T.1    Auerett, D.R.2    Prus, K.L.3    Miller, W.H.4    Nelson, D.J.5
  • 21
    • 0025049372 scopus 로고
    • Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2′,2′-difluorodeoxycytidine
    • Heinemann, V., Xu, Y-Z., Chubb, S., Sen, A , Hertel, L. W., Grindey, G. B., and Plunkett, W. Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2′,2′-difluorodeoxycytidine Mol. Pharmacol., 38: 567-572, 1990.
    • (1990) Mol. Pharmacol. , vol.38 , pp. 567-572
    • Heinemann, V.1    Xu, Y.-Z.2    Chubb, S.3    Sen, A.4    Hertel, L.W.5    Grindey, G.B.6    Plunkett, W.7
  • 22
    • 0024470862 scopus 로고
    • Induction of endonucleolytic DNA cleavage inhuman acute my-elogenous leukemia cells by etoposide, camptothecin and other cytotoxic anticancer drugs: A cautionary note
    • Kaufmann, S. H. Induction of endonucleolytic DNA cleavage inhuman acute my-elogenous leukemia cells by etoposide, camptothecin and other cytotoxic anticancer drugs: a cautionary note. Cancer Res., 49: 5870-5878, 1989
    • (1989) Cancer Res. , vol.49 , pp. 5870-5878
    • Kaufmann, S.H.1
  • 23
    • 0029060757 scopus 로고
    • Fludarabine and gemcitabine-induced apoptosis. incorporation of analogs into DNA is a critical event
    • Huang, P , and Plunkett, W. Fludarabine and gemcitabine-induced apoptosis. incorporation of analogs into DNA is a critical event Cancer Chemother. Pharmacol., 36: 181-188, 1995.
    • (1995) Cancer Chemother. Pharmacol. , vol.36 , pp. 181-188
    • Huang, P.1    Plunkett, W.2
  • 24
    • 0026685693 scopus 로고
    • 1-β-D-arabinosyl-cytosine and 5-azacytidine induce internucleosomal DNA fragmentation and cell death in thymocytes
    • Kizaki, H , Ohnishi, Y., Azuma, Y., Mizuma, Y , and Oshaka, F. 1-β-D-arabinosyl-cytosine and 5-azacytidine induce internucleosomal DNA fragmentation and cell death in thymocytes. Immunopharmacology, 24: 219-227, 1992.
    • (1992) Immunopharmacology , vol.24 , pp. 219-227
    • Kizaki, H.1    Ohnishi, Y.2    Azuma, Y.3    Mizuma, Y.4    Oshaka, F.5
  • 25
    • 0026788002 scopus 로고
    • Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation
    • Cohen, G. M., Sun, X M., Snowden, R. T., Dinsdale, D , and Skilleter, D. N. Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochem. J , 286. 331-334, 1992.
    • (1992) Biochem. J , vol.286 , pp. 331-334
    • Cohen, G.M.1    Sun, X.M.2    Snowden, R.T.3    Dinsdale, D.4    Skilleter, D.N.5
  • 26
    • 0027853057 scopus 로고
    • Etoposide-induced cytotoxicity in two human T-cell leukemic lines delayed loss of membrane permeability rather than DNA fragmentation as an indicator of programmed cell death
    • Catchpoole, D. R , and Stewart, B W. Etoposide-induced cytotoxicity in two human T-cell leukemic lines delayed loss of membrane permeability rather than DNA fragmentation as an indicator of programmed cell death. Cancer Res., 53: 4287-4296, 1993
    • (1993) Cancer Res. , vol.53 , pp. 4287-4296
    • Catchpoole, D.R.1    Stewart, B.W.2
  • 27
    • 0030040624 scopus 로고    scopus 로고
    • Genesis of discrete higher order DNA fragments in apoptotic human prostatic carcinoma cells
    • Rusnak, J M., Calmels, T. P G , Hoyt, D. G , Kondo, Y., Yalowich, J. C , and Lazo, J. S. Genesis of discrete higher order DNA fragments in apoptotic human prostatic carcinoma cells Mol Pharmacol , 49. 244-252, 1996.
    • (1996) Mol Pharmacol , vol.49 , pp. 244-252
    • Rusnak, J.M.1    Calmels, T.P.G.2    Hoyt, D.G.3    Kondo, Y.4    Yalowich, J.C.5    Lazo, J.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.