Relationship of β-cell function and autoantibodies to progression and nonprogression of subclinical type 1 diabetes: Follow-up of the Seattle Family Study

Diabetes

Volumn 48, Issue 1, 1999, Pages 170-175

  Greenbaum, Carla J ^a   Sears, Kari L ^b   Kahn, Steven E ^b   Palmer, Jerry P ^b  

^a Puget Sound Health Care System   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY;

ADOLESCENT; ADULT; ANTIBODY DETECTION; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESPONSE; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; UNITED STATES;

ADOLESCENT; ADULT; AUTOANTIBODIES; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; GLUCOSE; GLUTAMATE DECARBOXYLASE; HUMANS; INSULIN; ISLETS OF LANGERHANS; MALE; MIDDLE AGED; RISK FACTORS;

EID: 0032961804     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.1.170     Document Type: Article

References (26)

1. Boehm B, Manfras B, Seissler J, Schoffling K, Gluck M, Holzberger G, Seidl S. Kuhnl P, Trucco M, Scherbaum WA: Epidemiology and immunogenetic background of islet cell antibody-positive nondiabetic schoolchildren: Ulm-Frankfurt population study. Diabetes 40:1435-1439, 1991
2. Bonifacio E, Bingley PJ, Shattock M, Dean BM, Dunger D, Gale EA, Bottazzo GF: Quantification of islet cell antibodies and prediction of insulin-dependent diabetes. Lancet 335:147-149, 1990
3. Bingley PJ, Christie MR, Bonifacio E, Bonfanti R, Shattock M, Fonte M, Bottazzo GF, Gale EAM: Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody positive relatives. Diabetes 43:1304-1310, 1994
4. Karjalainen JK: Islet cell antibodies as predictive markers for IDDM in children with high background incidence of disease. Diabetes 39:1140-1150, 1990
5. Robert J, Deschamps I, Chevenne D, Roger M, Mogenet A, Boitard C: Relationship between first-phase insulin secretion and age, HLA, islet cell antibody status, and development of type I diabetes in 220 juvenile first-degree relatives of diabetic patients. Diabetes Care 14:718-723, 1991
6. McCulloch DK, Klaff LJ, Kahn SE, Schoenfeld SL, Greenbaum CJ, Mauseth RS, Benson EA, Nepom GT, Shewey L, Palmer JP: Nonprogression of subclinical β-cell dysfunction among first-degree relatives of IDDM patients: 5-yr follow-up of the Seattle Family Study. Diabetes 39:549-556, 1990
7. Greenbaum CJ, Palmer JP: Humoral immune markers: insulin autoantibodies. In Diabetes Prediction, Prevention, and Genetic Counseling. Palmer JP, Ed. Sussex, England, Wiley & Sons, 1996, p. 63-75
8. + relatives: the ICARUS data set. Diabetes 45:1720-1728, 1996
9. Schatz D, Krischer JP, Horne G, Riley W, Spillar R, Silverstein JH, Winter W, Muir A, Derovanesian D, Shah S, Maclaren MK: Islet cell antibodies predict insulin-dependent diabetes in United States school-age children as powerfully as in unaffected relatives. J Clin Invest 93:2403-2407, 1994
10. Ziegler AG, Ziegler R, Vardi P, Jackson RA, Soeldner JS, Eisenbarth GS: Lifetable analysis of progression to diabetes of anti-insulin autoantibody positive relatives of individuals with type 1 diabetes. Diabetes 38:1320-1325, 1989
11. DPT-1 Study Group: The Diabetes Prevention Trial of Type 1 Diabetes (DPT-1) (Abstract). J. Diabetes 43 (Suppl. 1): 159A, 1994
12. Becker F, Lenders W, Sauer H, Petzold R, Federlin K: Low rate of conversion to diabet es mellitus in healthy first-degree relatives of German type I diabetic patients (Abstract). Autoimmunity 15:59, 1993
13. Neifing J, Greenbaum C, Kahn S, McCulloch D, Barmeier H, Lernmark Å, Palmer J: Prospective evaluation of β-cell function in insulin autoantibody-positive relatives of insulin-dependent diabetic patients. Metabolism 42:482-486, 1993
14. Hegewald MJ, Schoenfeld SL, McCulloch DR, Greenbaum CJ, Klaff LJ, Palmer JP: Increased specificity and sensitivity of insulin autoantibody measurements in autoimmune, thyroid disease and type I diabetes. J Immunol Methods 154:61-68, 1992
15. Beard JC, Bergman RN, Ward WK, Porte DJ: The insulin sensitivity index in nondiabetic man: correlation between clamp-derived and IVGTT-derived values. Diabetes 35:362-369, 1986
16. Morgan CR, Lazarow A: Immunoassay of insulin: two antibody system: plasma insulin levels of normal, subdiabetic, and diabetic rats. Diabetes 12:115-136, 1963
17. Bergman RN, Ider YZ, Bowden CR, Cobelli C: Quantitative estimation of insulin sensitivity. Am J Physiol 236:E667-E677, 1979
18. Kahn SE, Prigeon RL, McCulloch DK, Boyko EJ, Bergman RN, Schwartz MW, Neifing JL, Ward WK, Beard JC, Palmer JP: Quantification of the relationship between insulin sensitivity and β-cell function in human subjects: evidence for a hyperbolic function. Diabetes 42:1663-1672, 1993
19. 55 and IA2 autoantibodies in IDDM can replace the histochemical islet cell antibody test. Diabetes 46:565-571. 1997
20. Bardet S, Rohmer V, Daugendre D, Marre M, Semana G, Limal JM, Allanic H, Charbonnel B, Sai P: Acute insulin response to intravenous glucose, glucagon. and arginine in some subjects at risk for type 1 (insulin-dependent) diabetes mellitus. Diabetologia 34:648-654, 1991
21. Ganda OP, Srikania S, Brink SJ, Morris MA, Gleason RE, Soeldner JS, Eisenbarth GS: Differential sensitivity to β-cell secretagogues in "early" type I diabet es mellitus. Diabetes 33:516-521, 1984
22. Heaton DA, Lazarus NR, Pyke DA, Leslie RDG: β-Cell response to intravenous glucose and glucagon in nondiabetic twins of patients with type 1 (insulin-dependent) diabetes mellitus. Diabetologia 32:814-817, 1989
23. Martin BC, Warram JH, Krolewski AS, Bergman RN, Soeldner JS, Kahn CR: Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study. Lancet 340:925-929, 1992
24. Mehta V, Palmer JP: The natural history of the IDDM disease process. In Prediction, Prevention, and Genetic Counseling in IDDM. Palmer JP, Ed. New York, Wiley & Sons, 1996, p. 3-16
25. Hiltunen M, Hyoty H, Knip M, Ilonen J. Reijonen H, Vahasalo P, Roivainen M, Lonnrot M, Leinikki P. Hovi T, Akerblom H: Islet cell antibody seroconversion in children is temporally associated with enterovirus infections. J Infect Dis 175:554-560, 1997
26. Hyoty H, Hiltunen M, Knip M, Laakkonen M, Vahasalo P, Karjalainen J, Koskela P, Roivaninen M, Leinikki P, Hovi T, Akerblom H: A prospective study of the role of Coxsackie B and other ent erovirus infections in the pathogenesis of IDDM. Diabetes 44:652-607, 1995