메뉴 건너뛰기




Volumn 12, Issue 4, 1999, Pages 279-287

Only multiple autoantibodies to islet cells (ICA), insulin, GAD65, IA-2 and IA-2β predict immune-mediated (type 1) diabetes in relatives

Author keywords

Autoantibodies; GAD65; HLA DR DQ; IA 2; IA 2 ; Prediction; Relatives; Type 1 diabetes

Indexed keywords

AUTOANTIBODY; GLUTAMATE DECARBOXYLASE; INSULIN;

EID: 0033020127     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.1999.0281     Document Type: Article
Times cited : (104)

References (44)
  • 1
    • 0028779842 scopus 로고
    • The pathogenesis of insulin dependent diabetes
    • Atkinson M.A., Maclaren N.K. The pathogenesis of insulin dependent diabetes. N. Engl. J. Med. 331:1994;1428-1436.
    • (1994) N. Engl. J. Med. , vol.331 , pp. 1428-1436
    • Atkinson, M.A.1    Maclaren, N.K.2
  • 5
    • 0019959221 scopus 로고
    • Autoantibodies in newly diagnosed diabetic children with immunoprecipitate human pancreatic islet cell proteins
    • Baekksekov S., Neilsen J.H., Marner B., Bilde T., Ludvigsson J., Lernmark A. Autoantibodies in newly diagnosed diabetic children with immunoprecipitate human pancreatic islet cell proteins. Nature. 298:1982;167-169.
    • (1982) Nature , vol.298 , pp. 167-169
    • Baekksekov, S.1    Neilsen, J.H.2    Marner, B.3    Bilde, T.4    Ludvigsson, J.5    Lernmark, A.6
  • 7
    • 0029975769 scopus 로고    scopus 로고
    • IA-2, A transmembrane protein of the protein tyrosine phosphate family, is a major autoantigen in insulin-dependent diabetes mellitus
    • Lan M.S., Wasserfall C., Maclaren N.K., Notkins A.L. IA-2, A transmembrane protein of the protein tyrosine phosphate family, is a major autoantigen in insulin-dependent diabetes mellitus. Proc. Natl. Acad. Sci. USA. 93:1996;6367-6370.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6367-6370
    • Lan, M.S.1    Wasserfall, C.2    Maclaren, N.K.3    Notkins, A.L.4
  • 8
    • 0028799911 scopus 로고
    • Pancreatic islet cell cytoplasmic antibodies in diabetes is represented by antibodies to islet cell antigen 512 and glutamin acid decarboxylase
    • Myers M.A., Rabin D.U., Rowley M.J. Pancreatic islet cell cytoplasmic antibodies in diabetes is represented by antibodies to islet cell antigen 512 and glutamin acid decarboxylase. Diabetes. 44:1995;1290-1295.
    • (1995) Diabetes , vol.44 , pp. 1290-1295
    • Myers, M.A.1    Rabin, D.U.2    Rowley, M.J.3
  • 9
    • 0029927890 scopus 로고    scopus 로고
    • Identification of a second transmembrane protein tyrosine phosphatase, IA-2β, as an autoantigen in insulin-dependent diabetes mellitus: Precursor of the 37-kDa-tryptic fragment
    • Lu J., Li Q., Xie H., Chen Z., Borovitskaya A.E., Maclaren N.K., Notkins A.L., Lan M.S. Identification of a second transmembrane protein tyrosine phosphatase, IA-2β, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa-tryptic fragment. Proc. Natl. Acad. Sci. USA. 93:1996;2307-2311.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2307-2311
    • Lu, J.1    Li, Q.2    Xie, H.3    Chen, Z.4    Borovitskaya, A.E.5    Maclaren, N.K.6    Notkins, A.L.7    Lan, M.S.8
  • 10
    • 0029784457 scopus 로고    scopus 로고
    • Autoantibodies to protein tyrosine phospatase-like proteins in type 1 diabetes
    • Kawasaki E., Eisenbarth G.S., Wasmeier C., Hutton J.C. Autoantibodies to protein tyrosine phospatase-like proteins in type 1 diabetes. Diabetes. 45:1996;1344-1349.
    • (1996) Diabetes , vol.45 , pp. 1344-1349
    • Kawasaki, E.1    Eisenbarth, G.S.2    Wasmeier, C.3    Hutton, J.C.4
  • 11
    • 0027529913 scopus 로고
    • Islet cell cytoplasmic autoantibody reactivity to gluamate decarboxylase in insulin-dependent diabetes
    • Atkinson M.A., Kaufman D.L., Newman D., Tobin A.J., Maclaren N.K. Islet cell cytoplasmic autoantibody reactivity to gluamate decarboxylase in insulin-dependent diabetes. J. Clin. Invest. 91:1993;350-356.
    • (1993) J. Clin. Invest. , vol.91 , pp. 350-356
    • Atkinson, M.A.1    Kaufman, D.L.2    Newman, D.3    Tobin, A.J.4    Maclaren, N.K.5
  • 12
    • 0026684592 scopus 로고
    • Antibodies to GAD and tryptic fragments of islet 64K antigen as distinct markers for development of IDDM. Studies with identical twins
    • Christie M.R., Tun R.Y., Lo S.S., Cassidy D., Brown T.J., Hollands J., Shattock M., Bottazzo G.F., Leslie R.D. Antibodies to GAD and tryptic fragments of islet 64K antigen as distinct markers for development of IDDM. Studies with identical twins. Diabetes. 41:1992;782-787.
    • (1992) Diabetes , vol.41 , pp. 782-787
    • Christie, M.R.1    Tun, R.Y.2    Lo, S.S.3    Cassidy, D.4    Brown, T.J.5    Hollands, J.6    Shattock, M.7    Bottazzo, G.F.8    Leslie, R.D.9
  • 13
    • 0028779439 scopus 로고
    • Nicotinamide and prevention of insulin-dependent diabetes mellitus. Rationale, effects toxicology and clinical experiences. ENDIT Group
    • Reimers J.I., Anderson H.U., Pociot F. Nicotinamide and prevention of insulin-dependent diabetes mellitus. Rationale, effects toxicology and clinical experiences. ENDIT Group. Ugeskr. Laeger. 156:1994;461-465.
    • (1994) Ugeskr. Laeger. , vol.156 , pp. 461-465
    • Reimers, J.I.1    Anderson, H.U.2    Pociot, F.3
  • 14
    • 0002704712 scopus 로고
    • Immune interventions in type I diabetes mellitus
    • Skyler J., Marks J. Immune interventions in type I diabetes mellitus. Diabetes Rev. 1:1993;15-42.
    • (1993) Diabetes Rev. , vol.1 , pp. 15-42
    • Skyler, J.1    Marks, J.2
  • 15
    • 0023630622 scopus 로고
    • Competitive insulin autoantibody assay; Prospective evaluation of subjects at high risk for development of type I diabetes mellitus
    • Vardi P., Dib S.A., Tuttleman M., Connelly J.E., Gribirgs, Riley W., Maclaren N.K., Eisenbarth G.S., Soeldner J.S. Competitive insulin autoantibody assay; prospective evaluation of subjects at high risk for development of type I diabetes mellitus. Diabetes. 36:1987;1286-1291.
    • (1987) Diabetes , vol.36 , pp. 1286-1291
    • Vardi, P.1    Dib, S.A.2    Tuttleman, M.3    Connelly, J.E.4    Gribirgs5    Riley, W.6    Maclaren, N.K.7    Eisenbarth, G.S.8    Soeldner, J.S.9
  • 16
    • 0030050339 scopus 로고    scopus 로고
    • DELISA: Sensitive nonisotopic assay for GAD autoantibodies, a key risk-assessment marker for insulin-dependent diabetes mellitus
    • Mehta H.B., Vold B., Minkin S., Ullman E.F. DELISA: sensitive nonisotopic assay for GAD autoantibodies, a key risk-assessment marker for insulin-dependent diabetes mellitus. Clin. Chem. 42:1996;263-269.
    • (1996) Clin. Chem. , vol.42 , pp. 263-269
    • Mehta, H.B.1    Vold, B.2    Minkin, S.3    Ullman, E.F.4
  • 18
    • 0029666353 scopus 로고    scopus 로고
    • Although DR3-DQB1* may be associated with multiple component diseases of the autoimmune polyglandular syndromes, the human leukocyte antigen DR4-DQB1*0302 haplotype is implicated only in beta cell autoimmunity
    • Huang W., Conner E., Dela Rosa T., Muir A., Schatz D., Silverstein J., Crockett S., She J., Maclaren N.K. Although DR3-DQB1* may be associated with multiple component diseases of the autoimmune polyglandular syndromes, the human leukocyte antigen DR4-DQB1*0302 haplotype is implicated only in beta cell autoimmunity. J. Clin. Endocrin. Metabol. 81:1996;1-5.
    • (1996) J. Clin. Endocrin. Metabol. , vol.81 , pp. 1-5
    • Huang, W.1    Conner, E.2    Dela Rosa, T.3    Muir, A.4    Schatz, D.5    Silverstein, J.6    Crockett, S.7    She, J.8    Maclaren, N.K.9
  • 19
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan E.L., Meier P. Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc. 53:1958;457-481.
    • (1958) J. Am. Stat. Assoc. , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 20
    • 0013886333 scopus 로고
    • Evaluation of survival data and two new rank order statistics arising in its consideration
    • Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chem. Rep. 50:1988;163-170.
    • (1988) Cancer Chem. Rep. , vol.50 , pp. 163-170
    • Mantel, N.1
  • 21
    • 0013635020 scopus 로고
    • EXACTB and CONF: Exact unconditional procedures for binomial data
    • Schuster J. EXACTB and CONF: exact unconditional procedures for binomial data. Am. Stat. 42:1988;234.
    • (1988) Am. Stat. , vol.42 , pp. 234
    • Schuster, J.1
  • 22
    • 0007559690 scopus 로고
    • The diabetes prevention trial type 1 diabetes (DPT-1): Design and implementation of the oral antigen (insulin) protocol
    • Dpt-1 Group
    • Schatz D., DPT-1 Group. The diabetes prevention trial type 1 diabetes (DPT-1): Design and implementation of the oral antigen (insulin) protocol. Diabetes*. 449(Suppl. 1):1995;A230.
    • (1995) Diabetes* , vol.4491 , pp. 230
    • Schatz, D.1
  • 23
    • 0028172563 scopus 로고
    • GAD65 autoantibodies increase the predictability but not the sensitivity of islet cell insulin autoantibodies for developing insulin dependent diabetes mellitus
    • Schott M., Schatz D., Atkinson M., Krisher J., Mehta H., Vold B., Maclaren N. GAD65 autoantibodies increase the predictability but not the sensitivity of islet cell insulin autoantibodies for developing insulin dependent diabetes mellitus. J. Autoimmun. 7:1994;865-872.
    • (1994) J. Autoimmun. , vol.7 , pp. 865-872
    • Schott, M.1    Schatz, D.2    Atkinson, M.3    Krisher, J.4    Mehta, H.5    Vold, B.6    Maclaren, N.7
  • 24
    • 0027942922 scopus 로고
    • So glutamic acid decarboxylase antibodies improve the prediction of IDDM in first-degree relatives at risk for IDDM?
    • Schmidli R.S., Coleman P.G., Harrison L.C. So glutamic acid decarboxylase antibodies improve the prediction of IDDM in first-degree relatives at risk for IDDM? J. Autoimmun. 7:1994;873-879.
    • (1994) J. Autoimmun. , vol.7 , pp. 873-879
    • Schmidli, R.S.1    Coleman, P.G.2    Harrison, L.C.3
  • 25
    • 0028258126 scopus 로고
    • Latent autoimmune diabetes mellitus in adults (LADA): The role of autoantibodies to glutamic acid decarboxylase in diagnosis and prediction of insulin dependency
    • Zimmet P.Z., Tuomi T., Mackay I.R., Rowley M.J., Knowles W., Cohen M., Lang D.A. Latent autoimmune diabetes mellitus in adults (LADA): the role of autoantibodies to glutamic acid decarboxylase in diagnosis and prediction of insulin dependency. Diabetes Med. 11:1994;299-303.
    • (1994) Diabetes Med. , vol.11 , pp. 299-303
    • Zimmet, P.Z.1    Tuomi, T.2    Mackay, I.R.3    Rowley, M.J.4    Knowles, W.5    Cohen, M.6    Lang, D.A.7
  • 28
    • 0030175880 scopus 로고    scopus 로고
    • Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specifications determines risk of type 1 diabetes
    • Verge C.F., Gianni R., Kawasaski E., Yu L., Pietropaola, Chase H.P., Eisenbrarth G.S. Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specifications determines risk of type 1 diabetes. J. Autoimmun. 9:1996;379-383.
    • (1996) J. Autoimmun. , vol.9 , pp. 379-383
    • Verge, C.F.1    Gianni, R.2    Kawasaski, E.3    Yu, L.4    Pietropaola5    Chase, H.P.6    Eisenbrarth, G.S.7
  • 29
    • 0029995958 scopus 로고    scopus 로고
    • Prediction of type 1 diabetes in first degree relatives using a combination of insulin, GAD and ICA512bc/IA-2 autoantibodies
    • Verge C.F., Gianani R., Kawasaki E., Chase H., Eisenbarth G.S. Prediction of type 1 diabetes in first degree relatives using a combination of insulin, GAD and ICA512bc/IA-2 autoantibodies. Diabetes. 45:1996;926-933.
    • (1996) Diabetes , vol.45 , pp. 926-933
    • Verge, C.F.1    Gianani, R.2    Kawasaki, E.3    Chase, H.4    Eisenbarth, G.S.5
  • 31
    • 0028154865 scopus 로고
    • Antibodies to islet 37 k antigen, but not to glutamate decarboxylase, discriminate rapid progression to IDDM in endocrine autoimmunity
    • Christie M.R., Genovese S., Cassidy D., Bosi E., Brown T.J., Lai M., Bonifacio E., Bottazzo G.F. Antibodies to islet 37 k antigen, but not to glutamate decarboxylase, discriminate rapid progression to IDDM in endocrine autoimmunity. Diabetes. 43:1994;1254-1259.
    • (1994) Diabetes , vol.43 , pp. 1254-1259
    • Christie, M.R.1    Genovese, S.2    Cassidy, D.3    Bosi, E.4    Brown, T.J.5    Lai, M.6    Bonifacio, E.7    Bottazzo, G.F.8
  • 32
    • 0028893973 scopus 로고
    • Anti-37 kDa antibodies are associated with the development of IDDM in individuals with islet cell antibodies
    • Ongagna J.C., Levy-Marchal C. Anti-37 kDa antibodies are associated with the development of IDDM in individuals with islet cell antibodies. Diabetologia. 38:1995;370-375.
    • (1995) Diabetologia , vol.38 , pp. 370-375
    • Ongagna, J.C.1    Levy-Marchal, C.2
  • 33
    • 0028113695 scopus 로고
    • A universal model of antibody prediction (MAP) of type 1 diabetes in children
    • Elliott R.B., Pilchner C.C. A universal model of antibody prediction (MAP) of type 1 diabetes in children. J. Autoimmun. 7:1994;881-888.
    • (1994) J. Autoimmun. , vol.7 , pp. 881-888
    • Elliott, R.B.1    Pilchner, C.C.2
  • 36
    • 0025841845 scopus 로고
    • Identification and cloning of a granule autoantigen carboxypeptidase-H) associated with type 1 diabetes
    • Castano L., Russo E., Zhou L., Lipes M.A., Eisenbarth G.S. Identification and cloning of a granule autoantigen carboxypeptidase-H) associated with type 1 diabetes. J. Clin. Endocrinol. Metab. 73:1991;1197-1201.
    • (1991) J. Clin. Endocrinol. Metab. , vol.73 , pp. 1197-1201
    • Castano, L.1    Russo, E.2    Zhou, L.3    Lipes, M.A.4    Eisenbarth, G.S.5
  • 37
    • 0027515474 scopus 로고
    • Sulphatide and sulphatide antibodies in insulin-dependent diabetes mellitus
    • Buschard K., Josefsen K., Horn T., Fredman P. Sulphatide and sulphatide antibodies in insulin-dependent diabetes mellitus. Lancet. 342:1993;840.
    • (1993) Lancet , vol.342 , pp. 840
    • Buschard, K.1    Josefsen, K.2    Horn, T.3    Fredman, P.4
  • 38
    • 0027316131 scopus 로고
    • Monoclonal antibody to rubella virus capsid protein recognizes a beta-cell antigen
    • Karounos D.G., Molinsky J.S., Thomas J.W. Monoclonal antibody to rubella virus capsid protein recognizes a beta-cell antigen. J. Immunol. 150:1993;3080-3085.
    • (1993) J. Immunol. , vol.150 , pp. 3080-3085
    • Karounos, D.G.1    Molinsky, J.S.2    Thomas, J.W.3
  • 41
    • 0028020408 scopus 로고
    • Sera from patients with IDDM and healthy individuals have antibodies to ICA69 on western blots but do not immunoprecipitate liquid phase antigen
    • Lampasona V., Ferrari M., Bosi E., Pastore R.M., Bingley P.J., Bonifacio E. Sera from patients with IDDM and healthy individuals have antibodies to ICA69 on western blots but do not immunoprecipitate liquid phase antigen. J. Autoimmun. 7:1994;665-674.
    • (1994) J. Autoimmun. , vol.7 , pp. 665-674
    • Lampasona, V.1    Ferrari, M.2    Bosi, E.3    Pastore, R.M.4    Bingley, P.J.5    Bonifacio, E.6
  • 42
    • 0027490736 scopus 로고
    • Insulin autoantibodies and high titre islet cell antibodies are preferentially associated with the HLA DQA1*0301-DQB1* 0302 haplotype at clinical onset of type 1 (insulin-dependent) diabetes mellitus before age 10 years, but not at onset between age 10 and 40 years
    • Vandewalle C.L., Decraene T., Schuit F.C., DeLeeuw I.H., Pipeleers D.G., Gorus F.K. Insulin autoantibodies and high titre islet cell antibodies are preferentially associated with the HLA DQA1*0301-DQB1* 0302 haplotype at clinical onset of type 1 (insulin-dependent) diabetes mellitus before age 10 years, but not at onset between age 10 and 40 years. Diabetologia. 36:1993;1155-1162.
    • (1993) Diabetologia , vol.36 , pp. 1155-1162
    • Vandewalle, C.L.1    Decraene, T.2    Schuit, F.C.3    Deleeuw, I.H.4    Pipeleers, D.G.5    Gorus, F.K.6
  • 43
    • 8944250212 scopus 로고    scopus 로고
    • Glutamic acid decarboxylase antibodies in relations to other autoantibodies and genetic risk markers in children with newly diagnosed insulin-dependent diabetes
    • Sabbah E., Kulmala P., Veijola R., Vahasalo P., Karjalainen J., Tuomilehto-Wolf E., Akerblom H.K., Knip M. Glutamic acid decarboxylase antibodies in relations to other autoantibodies and genetic risk markers in children with newly diagnosed insulin-dependent diabetes. J. Clin. Endocrinol. Metab. 81:1996;2455-2459.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 2455-2459
    • Sabbah, E.1    Kulmala, P.2    Veijola, R.3    Vahasalo, P.4    Karjalainen, J.5    Tuomilehto-Wolf, E.6    Akerblom, H.K.7    Knip, M.8
  • 44
    • 0030956660 scopus 로고    scopus 로고
    • Diversification of T cell responses to carboxy-terminal determinants within the 65-kD heat-shock protein is involved in regulation of autoimmune arthritis
    • Moudgil K.D., Chang T.T., Eradat H., Chen A.M., Gupta R.S., Brahm E., Sercarz E.E. Diversification of T cell responses to carboxy-terminal determinants within the 65-kD heat-shock protein is involved in regulation of autoimmune arthritis. J. Exp. Med. 18:1997;1307-1316.
    • (1997) J. Exp. Med. , vol.18 , pp. 1307-1316
    • Moudgil, K.D.1    Chang, T.T.2    Eradat, H.3    Chen, A.M.4    Gupta, R.S.5    Brahm, E.6    Sercarz, E.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.