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Volumn 24, Issue 3, 2002, Pages 231-242

Genetics and environmental factors in endocrine/organ-specific autoimmunity: Have there been any major advances?

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNITY; ENVIRONMENTAL FACTOR; GENETIC HETEROGENEITY; HLA SYSTEM; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; T LYMPHOCYTE; THYMUS;

EID: 0036452445     PISSN: 03444325     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00281-002-0107-x     Document Type: Review
Times cited : (7)

References (78)
  • 1
    • 0346599403 scopus 로고    scopus 로고
    • An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
    • Aaltonen J, Björses P, Perheentupa J, et al (1997) An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Nat Genet 17:399
    • (1997) Nat Genet , vol.17 , pp. 399
    • Aaltonen, J.1    Björses, P.2    Perheentupa, J.3
  • 2
    • 0034987197 scopus 로고    scopus 로고
    • Peptide and MHC specific breaking of humoral tolerance to native insulin with the B:9-23 peptide in diabetes prone and normal mice
    • Abiru N, Maniatis AK, Yu L, et al (2001) Peptide and MHC specific breaking of humoral tolerance to native insulin with the B:9-23 peptide in diabetes prone and normal mice. Diabetes 50:1274
    • (2001) Diabetes , vol.50 , pp. 1274
    • Abiru, N.1    Maniatis, A.K.2    Yu, L.3
  • 3
    • 4244008351 scopus 로고    scopus 로고
    • Induction of insulitis in BALB/c mice
    • Abiru N, Moriyama H, Liu E, et al (2001) Induction of insulitis in BALB/c mice. Diabetes 50:A257
    • (2001) Diabetes , vol.50
    • Abiru, N.1    Moriyama, H.2    Liu, E.3
  • 4
    • 0003164020 scopus 로고    scopus 로고
    • Emergence of diabetes associated autoantibodies in the nutritional prevention of IDDM(TRIGR) project
    • Akerblom HK, Virtanen SM, Hamalainen A, et al (1999) Emergence of diabetes associated autoantibodies in the nutritional prevention of IDDM(TRIGR) project. Diabetes 48:A45
    • (1999) Diabetes , vol.48
    • Akerblom, H.K.1    Virtanen, S.M.2    Hamalainen, A.3
  • 6
    • 0025331496 scopus 로고
    • Analysis of HLA-DQ genotypes and susceptibility in insulin- dependent diabetes mellitus
    • Baisch JM, Weeks T, Giles R, et al (1990) Analysis of HLA-DQ genotypes and susceptibility in insulin- dependent diabetes mellitus. N Engl J Med 322:1836
    • (1990) N Engl J Med , vol.322 , pp. 1836
    • Baisch, J.M.1    Weeks, T.2    Giles, R.3
  • 8
    • 0035821985 scopus 로고    scopus 로고
    • Treatment of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) by allogeneic bone marrow transplantation
    • Baud O, Goulet O, Canioni D, et al (2001) Treatment of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) by allogeneic bone marrow transplantation. N Engl J Med 344:1758
    • (2001) N Engl J Med , vol.344 , pp. 1758
    • Baud, O.1    Goulet, O.2    Canioni, D.3
  • 9
    • 0002830060 scopus 로고
    • Dissecting IDDM-2-VNTR-encoded predisposition to type I diabetes
    • Bennett ST, Barnett AH, Bain SC, et al (1995) Dissecting IDDM-2-VNTR-encoded predisposition to type I diabetes. Autoimmunity 21:16
    • (1995) Autoimmunity , vol.21 , pp. 16
    • Bennett, S.T.1    Barnett, A.H.2    Bain, S.C.3
  • 10
    • 0028871202 scopus 로고
    • Susceptibility to human type I diabetes at IDDM 2 is determined by tandem repeat variation at the insulin gene minisatellite locus
    • Bennett ST, Lucassen AM, Gough SCL, et al (1995) Susceptibility to human type I diabetes at IDDM 2 is determined by tandem repeat variation at the insulin gene minisatellite locus. Nat Genet 9:284
    • (1995) Nat Genet , vol.9 , pp. 284
    • Bennett, S.T.1    Lucassen, A.M.2    Gough, S.C.L.3
  • 11
    • 0030695027 scopus 로고    scopus 로고
    • Prediction of IDDM in the general population: Strategies based on combinations of autoantibody markers
    • Bingley PJ, Bonifacio E, Williams AJK, et al (1997) Prediction of IDDM in the general population: Strategies based on combinations of autoantibody markers. Diabetes 46:1701
    • (1997) Diabetes , vol.46 , pp. 1701
    • Bingley, P.J.1    Bonifacio, E.2    Williams, A.J.K.3
  • 12
    • 0242536432 scopus 로고    scopus 로고
    • Mutations in the AIRE gene: Effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein
    • Bjorses P, Halonen M, Palvimo JJ, et al (2000) Mutations in the AIRE gene: Effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein. Am J Hum Genet 66:378
    • (2000) Am J Hum Genet , vol.66 , pp. 378
    • Bjorses, P.1    Halonen, M.2    Palvimo, J.J.3
  • 13
    • 0033169037 scopus 로고    scopus 로고
    • Early autoantibody responses in prediabetes are IgG1 dominated and suggest antigen-specific regulation
    • Bonifacio E, Scirpoli M, Kredel K, et al (1999) Early autoantibody responses in prediabetes are IgG1 dominated and suggest antigen-specific regulation. J Immunol 163:525
    • (1999) J Immunol , vol.163 , pp. 525
    • Bonifacio, E.1    Scirpoli, M.2    Kredel, K.3
  • 14
    • 0034526617 scopus 로고    scopus 로고
    • JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
    • Chatila TA, Blaeser F, Ho N, et al (2000) JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J Clin Invest 106:R75
    • (2000) J Clin Invest , vol.106
    • Chatila, T.A.1    Blaeser, F.2    Ho, N.3
  • 15
    • 0033552391 scopus 로고    scopus 로고
    • Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis
    • Coles AJ, Wing M, Smith S, et al (1999) Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis. Lancet 354:1691
    • (1999) Lancet , vol.354 , pp. 1691
    • Coles, A.J.1    Wing, M.2    Smith, S.3
  • 16
    • 0033941714 scopus 로고    scopus 로고
    • Susceptibility to diabetes is widely distributed in normal class IIu haplotype rats
    • Ellerman KE, Like AA (2000) Susceptibility to diabetes is widely distributed in normal class IIu hap-lotype rats. Diabetologia 43:890
    • (2002) Diabetologia , vol.43 , pp. 890
    • Ellerman, K.E.1    Like, A.A.2
  • 17
    • 0021247996 scopus 로고
    • Congenital rubella syndrome as a model for type I (insulin- dependent) diabetes mellitus: Increased prevalence of islet cell surface antibodies
    • Ginsberg-Fellner F, Witt ME, Yagihashi S, et al (1984) Congenital rubella syndrome as a model for type I (insulin- dependent) diabetes mellitus: Increased prevalence of islet cell surface antibodies. Diabetologia 27 Suppl:87
    • (1984) Diabetologia , vol.27 , Issue.SUPPL. , pp. 87
    • Ginsberg-Fellner, F.1    Witt, M.E.2    Yagihashi, S.3
  • 18
    • 0028122921 scopus 로고
    • Transplantation of T cell-mediated, lymphoreticular disease from the scurfy (sf) mouse
    • Godfrey VL, Rouse BT, Wilkinson JE (1994) Transplantation of T cell-mediated, lymphoreticular disease from the scurfy (sf) mouse. Am J Pathol 145:281
    • (1994) Am J Pathol , vol.145 , pp. 281
    • Godfrey, V.L.1    Rouse, B.T.2    Wilkinson, J.E.3
  • 19
    • 0030915756 scopus 로고    scopus 로고
    • The role of enteroviral infections in the development of IDDM: Limitations of current approaches
    • Graves PM, Rewers M (1997) The role of enteroviral infections in the development of IDDM: Limitations of current approaches. Diabetes 46:161
    • (1997) Diabetes , vol.46 , pp. 161
    • Graves, P.M.1    Rewers, M.2
  • 20
    • 0029882216 scopus 로고    scopus 로고
    • High prevalence of diabetes mellitus in patients with chronic hepatitis c - A case-control study
    • Grimbert S, Valensi P, Levymarchal C, et al (1996) High prevalence of diabetes mellitus in patients with chronic hepatitis c - A case-control study. Gastroenterol Clin Biol 20:544
    • (1996) Gastroenterol Clin Biol , vol.20 , pp. 544
    • Grimbert, S.1    Valensi, P.2    Levymarchal, C.3
  • 21
    • 0034351867 scopus 로고    scopus 로고
    • ss-cell autoantibodies, human leukocyte antigen II alleles, and type 1 diabetes in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
    • Gylling M, Tuomi T, Bjorses P, et al (2000) ss-cell autoantibodies, human leukocyte antigen II alleles, and type 1 diabetes in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. J Clin Endocrinol Metab 85:4434
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4434
    • Gylling, M.1    Tuomi, T.2    Bjorses, P.3
  • 22
    • 0033590981 scopus 로고    scopus 로고
    • Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla
    • Heino M, Peterson P, Kudoh J, et al (1999) Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla. Biochem Biophys Res Commun 257:821
    • (1999) Biochem Biophys Res Commun , vol.257 , pp. 821
    • Heino, M.1    Peterson, P.2    Kudoh, J.3
  • 23
    • 0032902386 scopus 로고    scopus 로고
    • Mutation analyses of North American APS-1 patients
    • Heino M, Scott HS, Chen Q, et al (1999) Mutation analyses of North American APS-1 patients. Hum Mutat 13:69
    • (1999) Hum Mutat , vol.13 , pp. 69
    • Heino, M.1    Scott, H.S.2    Chen, Q.3
  • 24
    • 0028941761 scopus 로고
    • Autoimmune endocrine disease induced by recombinant interferon-α therapy for chronic active type C hepatitis
    • Imagawa A, Itoh N, Hanafusa T, et al (1995) Autoimmune endocrine disease induced by recombinant interferon-α therapy for chronic active type C hepatitis. J Clin Endocrinol Metab 80:922
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 922
    • Imagawa, A.1    Itoh, N.2    Hanafusa, T.3
  • 25
    • 0345535842 scopus 로고    scopus 로고
    • The onset age of type 1 diabetes in Finnish children has become younger
    • The Finnish Childhood Diabetes Registry Group
    • Karvonen M, Pitkaniemi J, Tuomilehto J (1999) The onset age of type 1 diabetes in Finnish children has become younger. The Finnish Childhood Diabetes Registry Group. Diabetes Care 22:1066
    • (1999) Diabetes Care , vol.22 , pp. 1066
    • Karvonen, M.1    Pitkaniemi, J.2    Tuomilehto, J.3
  • 26
    • 0031737601 scopus 로고    scopus 로고
    • Transmission of DQ haplotypes to patients with type 1 diabetes
    • Kawasaki E, Noble J, Erlich H, et al (1998) Transmission of DQ haplotypes to patients with type 1 diabetes. Diabetes 47:1971
    • (1998) Diabetes , vol.47 , pp. 1971
    • Kawasaki, E.1    Noble, J.2    Erlich, H.3
  • 27
    • 0028881617 scopus 로고
    • The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription
    • Kennedy GC, German MS, Rutter WJ (1995) The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription. Nat Genet 9:293
    • (1995) Nat Genet , vol.9 , pp. 293
    • Kennedy, G.C.1    German, M.S.2    Rutter, W.J.3
  • 28
    • 0028882717 scopus 로고
    • Population analysis of protection by HLA-DR and DQ genes from insulin-dependent diabetes mellitus in Swedish children with insulin-dependent diabetes and controls
    • Kockum I, Sanjeevi CB, Eastman S, et al (1995) Population analysis of protection by HLA-DR and DQ genes from insulin-dependent diabetes mellitus in Swedish children with insulin-dependent diabetes and controls. Eur J Immunogenet 22:443
    • (1995) Eur J Immunogenet , vol.22 , pp. 443
    • Kockum, I.1    Sanjeevi, C.B.2    Eastman, S.3
  • 29
    • 0028363971 scopus 로고
    • Increasing incidence of IDDM a consequence of improved hygiene?
    • Kolb H, Elliott RB (1994) Increasing incidence of IDDM a consequence of improved hygiene? Diabetologia 37:729
    • (1994) Diabetologia , vol.37 , pp. 729
    • Kolb, H.1    Elliott, R.B.2
  • 30
    • 0035380479 scopus 로고    scopus 로고
    • Structure of a human insulin peptide/HLA-DQ8 complex and susceptibility to type 1 diabetes
    • Lee KH, Wucherpfennig KW, Wiley DC (2001) Structure of a human insulin peptide/HLA-DQ8 complex and susceptibility to type 1 diabetes. Nat Immunol 2:501
    • (2000) Nat Immunol , vol.2 , pp. 501
    • Lee, K.H.1    Wucherpfennig, K.W.2    Wiley, D.C.3
  • 31
    • 0033624114 scopus 로고    scopus 로고
    • Enterovirus infection as a risk factor for beta-cell autoimmunity in a prospectively observed birth cohort: The Finnish Diabetes Prediction and Prevention Study
    • Lonnrot M, Korpela K, Knip M, et al (2000) Enterovirus infection as a risk factor for beta-cell autoimmunity in a prospectively observed birth cohort: The Finnish Diabetes Prediction and Prevention Study. Diabetes 49:1314
    • (2000) Diabetes , vol.49 , pp. 1314
    • Lonnrot, M.1    Korpela, K.2    Knip, M.3
  • 32
    • 0028964371 scopus 로고
    • Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype
    • Lucassen AM, Screaton GR, Julier C, et al (1995) Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype. Hum Mol Genet 4:501
    • (1995) Hum Mol Genet , vol.4 , pp. 501
    • Lucassen, A.M.1    Screaton, G.R.2    Julier, C.3
  • 33
    • 0031055118 scopus 로고    scopus 로고
    • Heterogeneous reactivity patterns of HLA-DQ-restricted, small intestinal T-cell clones from patients with celiac disease
    • Lundin KE, Sollid LM, Anthonsen D, et al (1997) Heterogeneous reactivity patterns of HLA-DQ-restricted, small intestinal T-cell clones from patients with celiac disease. Gastroenterology 112:752
    • (1997) Gastroenterology , vol.112 , pp. 752
    • Lundin, K.E.1    Sollid, L.M.2    Anthonsen, D.3
  • 34
    • 0026015205 scopus 로고    scopus 로고
    • Milk proteins in the etiology of insulin-dependent diabetes mellitu s (IDDM)
    • Martin JM, Trink B, Daneman D, et al (1998) Milk proteins in the etiology of insulin-dependent diabetes mellitu s (IDDM). Ann Med 23:447
    • (1998) Ann Med , vol.23 , pp. 447
    • Martin, J.M.1    Trink, B.2    Daneman, D.3
  • 35
    • 0032171644 scopus 로고    scopus 로고
    • A very high level of crossreactivity is an essential feature of the T-cell receptor
    • Mason D (1998) A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol Today 19:395
    • (1998) Immunol Today , vol.19 , pp. 395
    • Mason, D.1
  • 36
    • 0035869593 scopus 로고    scopus 로고
    • The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deaminated forms of the alpha- and beta-chains of fibrin
    • Masson-Bessiere C, Sebbag M, Girbal-Neuhauser E, et al (2001) The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deaminated forms of the alpha- and beta-chains of fibrin. J Immunol 166:4177
    • (2001) J Immunol , vol.166 , pp. 4177
    • Masson-Bessiere, C.1    Sebbag, M.2    Girbal-Neuhauser, E.3
  • 37
    • 0035069590 scopus 로고    scopus 로고
    • Screening for an AIRE-1 mutation in patients with Addison's disease, type 1 diabetes, Graves' disease and Hashimoto's thyroiditis as well as in APECED syndrome
    • Meyer G, Donner H, Herwig J, et al (2001) Screening for an AIRE-1 mutation in patients with Addison's disease, type 1 diabetes, Graves' disease and Hashimoto's thyroiditis as well as in APECED syndrome. Clin Endocrinol (Oxf) 54:335
    • (2001) Clin Endocrinol (Oxf) , vol.54 , pp. 335
    • Meyer, G.1    Donner, H.2    Herwig, J.3
  • 38
    • 0036525525 scopus 로고    scopus 로고
    • ICA512(IA-2) Epitope specific assays distinguish transient from diabetes associated autoantibodies
    • Miao D, Yu L, Tiberti C, et al (2002) ICA512(IA-2) Epitope specific assays distinguish transient from diabetes associated autoantibodies. J Autoimmun 18(2):191
    • (2002) J Autoimmun , vol.18 , Issue.2 , pp. 191
    • Miao, D.1    Yu, L.2    Tiberti, C.3
  • 39
    • 0031779478 scopus 로고    scopus 로고
    • Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
    • Molberg O, McAdam SN, Körner R, et al (1998) Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease. Nat Med 4:713
    • (1998) Nat Med , vol.4 , pp. 713
    • Molberg, O.1    McAdam, S.N.2    Körner, R.3
  • 40
    • 0035123883 scopus 로고    scopus 로고
    • Autoimmune polyendocrine syndrome type 1 (APS I) in Norway
    • Myhre AG, Halonen M, Eskelin P, et al (2001) Autoimmune polyendocrine syndrome type 1 (APS I) in Norway. Clin Endocrinol (Oxf) 54:211
    • (2001) Clin Endocrinol (Oxf) , vol.54 , pp. 211
    • Myhre, A.G.1    Halonen, M.2    Eskelin, P.3
  • 41
    • 16944367194 scopus 로고    scopus 로고
    • Positional cloning of the APECED gene
    • Nagamine K, Peterson P, Scott HS, et al (1997) Positional cloning of the APECED gene. Nat Genet 17:393
    • (1997) Nat Genet , vol.17 , pp. 393
    • Nagamine, K.1    Peterson, P.2    Scott, H.S.3
  • 42
    • 0034454508 scopus 로고    scopus 로고
    • A heterozygous deletion of the autoimmune regulator (AIRE1) gene, autoimmune thyroid disease, and type 1 diabetes: No evidence for association
    • Nithiyananthan R, Heward JM, Allahabadia A, et al (2000) A heterozygous deletion of the autoim-mune regulator (AIRE1) gene, autoimmune thyroid disease, and type 1 diabetes: No evidence for association. J Clin Endocrinol Metab 85:1320
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1320
    • Nithiyananthan, R.1    Heward, J.M.2    Allahabadia, A.3
  • 43
    • 9444263686 scopus 로고    scopus 로고
    • Lack of association between early exposure to cow's milk protein and β-cell autoimmunity: Diabetes autoimmunity study in the young (DAISY)
    • Norris JM, Beaty B, Klingensmith G, et al (1996) Lack of association between early exposure to cow's milk protein and β-cell autoimmunity: Diabetes autoimmunity study in the young (DAISY). JAMA 276:609
    • (1996) JAMA , vol.276 , pp. 609
    • Norris, J.M.1    Beaty, B.2    Klingensmith, G.3
  • 44
    • 0033429304 scopus 로고    scopus 로고
    • Worldwide increase in incidence of Type I diabetes - The analysis of the data on published incidence trends
    • Onkamo P, Vaananen S, Karvonen M, et al (1999) Worldwide increase in incidence of Type I diabetes - The analysis of the data on published incidence trends. Diabetologia 42:1395
    • (1999) Diabetologia , vol.42 , pp. 1395
    • Onkamo, P.1    Vaananen, S.2    Karvonen, M.3
  • 45
    • 0035141865 scopus 로고    scopus 로고
    • Escape from tolerance in the human X-linked autoimmunity-allergic disregulation syndrome and the Scurfy mouse
    • Patel DD (2001) Escape from tolerance in the human X-linked autoimmunity-allergic disregulation syndrome and the Scurfy mouse. J Clin Invest 107:155
    • (2001) J Clin Invest , vol.107 , pp. 155
    • Patel, D.D.1
  • 46
    • 0032470812 scopus 로고    scopus 로고
    • A common and recurrent 13-bp deletion in the autoimmune regulator gene in British kindreds with autoimmune polyendocrinopathy type 1
    • Pearce SH, Cheetham T, Imrie H, et al (1998) A common and recurrent 13-bp deletion in the autoimmune regulator gene in British kindreds with autoimmune polyendocrinopathy type 1. Am J Hum Genet 63:1675
    • (1998) Am J Hum Genet , vol.63 , pp. 1675
    • Pearce, S.H.1    Cheetham, T.2    Imrie, H.3
  • 47
    • 0038824426 scopus 로고    scopus 로고
    • The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein
    • Pitkanen J, Doucas V, Sternsdorf T, et al (2000) The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein. J Biol Chem 275:16802
    • (2000) J Biol Chem , vol.275 , pp. 16802
    • Pitkanen, J.1    Doucas, V.2    Sternsdorf, T.3
  • 48
    • 0028151268 scopus 로고
    • The paternally inherited insulin gene B allele (1,428 FokI site) confers protection from insulin-dependent diabetes in families
    • Pugliese A, Awdeh ZL, Alper CA, et al (1994) The paternally inherited insulin gene B allele (1,428 FokI site) confers protection from insulin-dependent diabetes in families. J Autoimmun 7:687
    • (1994) J Autoimmun , vol.7 , pp. 687
    • Pugliese, A.1    Awdeh, Z.L.2    Alper, C.A.3
  • 49
    • 0028989040 scopus 로고
    • HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM
    • Pugliese A, Gianani R, Moromisato R, et al (1995) HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM. Diabetes 44:608
    • (1995) Diabetes , vol.44 , pp. 608
    • Pugliese, A.1    Gianani, R.2    Moromisato, R.3
  • 50
    • 18244421874 scopus 로고    scopus 로고
    • The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR-IDDM 2 susceptibility locus for type I diabetes
    • Pugliese A, Zeller M, Fernandez A, et al (1997) The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR-IDDM 2 susceptibility locus for type I diabetes. Nat Genet 15:293
    • (1997) Nat Genet , vol.15 , pp. 293
    • Pugliese, A.1    Zeller, M.2    Fernandez, A.3
  • 51
    • 4243924490 scopus 로고    scopus 로고
    • Sequence analysis of the DQB1*0602 allele in rare patients with type 1 diabetes
    • Pugliese A, Zeller M, Yu L, et al (1998) Sequence analysis of the DQB1*0602 allele in rare patients with type 1 diabetes. Diabetes 47 (Suppl 1):A198
    • (1998) Diabetes , vol.47 , Issue.SUPPL. 1
    • Pugliese, A.1    Zeller, M.2    Yu, L.3
  • 52
    • 0022812136 scopus 로고
    • Congenital rubella. Monoclonal antibody-defined T cell abnormalities in young adults
    • Rabinowe SL, George KL, Loughlin R, et al (1986) Congenital rubella. Monoclonal antibody-defined T cell abnormalities in young adults. Am J Med 81:779
    • (1986) Am J Med , vol.81 , pp. 779
    • Rabinowe, S.L.1    George, K.L.2    Loughlin, R.3
  • 53
    • 0033756922 scopus 로고    scopus 로고
    • DR and DQ associated protection from type 1 diabetes: Comparison of DRB1*1401 and DQA1*0102-DQB1*0602
    • Redondo MJ, Kawasaki E, Mulgrew CL, et al (2000) DR and DQ associated protection from type 1 diabetes: Comparison of DRB1*1401 and DQA1*0102-DQB1*0602. J Clin Endocrinol Metab 85:3793
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3793
    • Redondo, M.J.1    Kawasaki, E.2    Mulgrew, C.L.3
  • 54
    • 8944258928 scopus 로고    scopus 로고
    • Newborn screening for HLA markers associated with IDDM: Diabetes autoimmunity study in the young (DAISY)
    • Rewers M, Bugawan TL, Norris JM, et al (1996) Newborn screening for HLA markers associated with IDDM: Diabetes autoimmunity study in the young (DAISY). Diabetologia 39:807
    • (1996) Diabetologia , vol.39 , pp. 807
    • Rewers, M.1    Bugawan, T.L.2    Norris, J.M.3
  • 55
    • 0032924111 scopus 로고    scopus 로고
    • AIRE encodes a nuclear protein colocalizing with cytoskeletal filaments: Altered sub-cellular distribution of mutants lacking the PHD zinc fingers
    • Rinderle C, Christensen HM, Schweiger S, et al (1999) AIRE encodes a nuclear protein colocalizing with cytoskeletal filaments: Altered sub-cellular distribution of mutants lacking the PHD zinc fingers. Hum Mol Genet 8:277
    • (1999) Hum Mol Genet , vol.8 , pp. 277
    • Rinderle, C.1    Christensen, H.M.2    Schweiger, S.3
  • 56
    • 0031753977 scopus 로고    scopus 로고
    • A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients
    • Rosatelli MC, Meloni A, Meloni A, et al (1998) A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients. Hum Genet 103:428
    • (1998) Hum Genet , vol.103 , pp. 428
    • Rosatelli, M.C.1    Meloni, A.2    Meloni, A.3
  • 58
    • 0035038458 scopus 로고    scopus 로고
    • Identification of a novel mutation in the autoimmune regulator (AIRE-1) gene in a French family with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
    • Saugier-Veber P, Drouot N, Wolf LM, et al (2001) Identification of a novel mutation in the autoimmune regulator (AIRE-1) gene in a French family with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. Eur J Endocrinol 144:347
    • (2001) Eur J Endocrinol , vol.144 , pp. 347
    • Saugier-Veber, P.1    Drouot, N.2    Wolf, L.M.3
  • 59
    • 0022532753 scopus 로고
    • Celiac disease in insulin-dependent diabetes mellitus
    • Savilahti E, Simell O, Koskimies S, et al (1986) Celiac disease in insulin-dependent diabetes mellitus. J Pediatr 108:690
    • (1986) J Pediatr , vol.108 , pp. 690
    • Savilahti, E.1    Simell, O.2    Koskimies, S.3
  • 60
    • 0031974911 scopus 로고    scopus 로고
    • Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies
    • Schellekens GA, Jong BA de, Hoogen FH van den, et al (1998) Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J Clin Invest 101:273
    • (1998) J Clin Invest , vol.101 , pp. 273
    • Schellekens, G.A.1    De Jong, B.A.2    Van den Hoogen, F.H.3
  • 62
    • 0030779118 scopus 로고    scopus 로고
    • A mechanism for the major histocompatibility complex-linked resistance to autoimmunity
    • Schmidt D, Verdaguer J, Averill N, et al (1997) A mechanism for the major histocompatibility complex-linked resistance to autoimmunity. J Exp Med 186:1059
    • (1997) J Exp Med , vol.186 , pp. 1059
    • Schmidt, D.1    Verdaguer, J.2    Averill, N.3
  • 63
    • 0032230236 scopus 로고    scopus 로고
    • Common mutations in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients of different origins
    • Scott HS, Heino M, Peterson P, et al (1998) Common mutations in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients of different origins. Mol Endocrinol 12:1112
    • (1998) Mol Endocrinol , vol.12 , pp. 1112
    • Scott, H.S.1    Heino, M.2    Peterson, P.3
  • 64
    • 0022965227 scopus 로고
    • Congenital rubella syndrome and diabetes: A review of epidemiologic, genetic, and immunologic factors
    • Shaver KA, Boughman JA, Nance WE (1985) Congenital rubella syndrome and diabetes: A review of epidemiologic, genetic, and immunologic factors. Am Ann Deaf 130:526
    • (1985) Am Ann Deaf , vol.130 , pp. 526
    • Shaver, K.A.1    Boughman, J.A.2    Nance, W.E.3
  • 65
    • 17744373659 scopus 로고    scopus 로고
    • Association analysis of the cytotoxic T lymphocyte antigen-4 (CTLA-4) and autoimmune regulator-1 (AIRE-1) genes in sporadic autoimmune Addison's disease
    • Vaidya B, Imrie H, Geatch DR, et al (2000) Association analysis of the cytotoxic T lymphocyte antigen-4 (CTLA-4) and autoimmune regulator-1 (AIRE-1) genes in sporadic autoimmune Addison's disease. J Clin Endocrinol Metab 85:688
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 688
    • Vaidya, B.1    Imrie, H.2    Geatch, D.R.3
  • 66
    • 0032528813 scopus 로고    scopus 로고
    • Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity
    • Van de Wal Y, Kooy Y, Veelen P van, et al (1998) Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity. J Immunol 161:1585
    • (1998) J Immunol , vol.161 , pp. 1585
    • Van de Wal, Y.1    Kooy, Y.2    Van Veelen, P.3
  • 67
    • 0023722804 scopus 로고
    • Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age
    • Vardi P, Ziegler AG, Matthews JH, et al (1988) Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age. Diabetes Care 11:736
    • (1988) Diabetes Care , vol.11 , pp. 736
    • Vardi, P.1    Ziegler, A.G.2    Matthews, J.H.3
  • 68
    • 0030175880 scopus 로고    scopus 로고
    • Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type I diabetes
    • Verge CF, Gianani R, Kawasaki E, et al (1996) Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type I diabetes. J Autoimmun 9:379
    • (1996) J Autoimmun , vol.9 , pp. 379
    • Verge, C.F.1    Gianani, R.2    Kawasaki, E.3
  • 69
    • 0029995958 scopus 로고    scopus 로고
    • Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies
    • Verge CF, Gianani R, Kawasaki E, et al (1996) Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies. Diabetes 45:926
    • (1996) Diabetes , vol.45 , pp. 926
    • Verge, C.F.1    Gianani, R.2    Kawasaki, E.3
  • 70
    • 0031738116 scopus 로고    scopus 로고
    • Combined use of autoantibodies (IA-2ab, Gadab, IAA, ICA) in type 1 diabetes: Combinatorial islet autoantibody workshop
    • Verge CF, Stenger D, Bonifacio E, et al (1998) Combined use of autoantibodies (IA-2ab, Gadab, IAA, ICA) in type 1 diabetes: Combinatorial islet autoantibody workshop. Diabetes 47:1857
    • (1998) Diabetes , vol.47 , pp. 1857
    • Verge, C.F.1    Stenger, D.2    Bonifacio, E.3
  • 71
    • 0032532064 scopus 로고    scopus 로고
    • Evidence for oligogenic inheritance of type 1A diabetes in a large Bedouin Arab family
    • Verge CF, Vardi P, Babu S, et al (1998) Evidence for oligogenic inheritance of type 1A diabetes in a large Bedouin Arab family. J Clin Invest 102:1569
    • (1998) J Clin Invest , vol.102 , pp. 1569
    • Verge, C.F.1    Vardi, P.2    Babu, S.3
  • 72
    • 0034598313 scopus 로고    scopus 로고
    • In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes
    • Wen L, Wong FS, Tang J, et al (2000) In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes. J Exp Med 191:97
    • (2000) J Exp Med , vol.191 , pp. 97
    • Wen, L.1    Wong, F.S.2    Tang, J.3
  • 74
    • 0028926223 scopus 로고
    • Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
    • Wucherpfennig KW, Strominger JL (1995) Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein. Cell 80:695
    • (1995) Cell , vol.80 , pp. 695
    • Wucherpfennig, K.W.1    Strominger, J.L.2
  • 75
    • 0029671122 scopus 로고    scopus 로고
    • NOD molecule on the development of insulitis and diabetes in the non-obese diabetic (NOD) mouse
    • NOD molecule on the development of insulitis and diabetes in the non-obese diabetic (NOD) mouse. Clin Exp Immunol 103:141
    • (1996) Clin Exp Immunol , vol.103 , pp. 141
    • Yamane, K.1    Yamamoto, K.2    Yoshikawa, Y.3
  • 76
    • 0032590058 scopus 로고    scopus 로고
    • DRB1*04 and DQ alleles: Expression of 21-hydroxylase autoantibodies and risk of progression to Addison's disease
    • Yu L, Brewer KW, Gates S, et al (1999) DRB1*04 and DQ alleles: Expression of 21-hydroxylase autoantibodies and risk of progression to Addison's disease. J Clin Endocrinol Metab 84:328
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 328
    • Yu, L.1    Brewer, K.W.2    Gates, S.3
  • 77
    • 0034652317 scopus 로고    scopus 로고
    • Early expression of antiinsulin autoantibodies of humans and the NOD mouse: Evidence for early determination of subsequent diabetes
    • Yu L, Robles DT, Abiru N, et al (2000) Early expression of antiinsulin autoantibodies of humans and the NOD mouse: Evidence for early determination of subsequent diabetes. Proc Natl Acad Sci USA 97:1701
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1701
    • Yu, L.1    Robles, D.T.2    Abiru, N.3
  • 78
    • 0034662906 scopus 로고    scopus 로고
    • Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
    • Zuklys S, Balciunaite G, Agarwal A, et al (2000) Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). J Immunol 165:1976
    • (2000) J Immunol , vol.165 , pp. 1976
    • Zuklys, S.1    Balciunaite, G.2    Agarwal, A.3


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