Increased orbitofrontal cortex levels of choline in depressed adolescents as detected by in vivo proton magnetic resonance spectroscopy

Biological Psychiatry

Volumn 48, Issue 11, 2000, Pages 1053-1061

  Steingard, Ronald J ^a,b   Yurgelun Todd, Deborah A ^a,d   Hennen, John ^a,d   Moore, JoEllyn C ^a,b   Moore, Constance M ^a,d   Vakili, Khashayar ^d   Young, Ashley D ^d   Katic, Alain ^a,b   Beardslee, William R ^a,c   Renshaw, Perry F ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b CAMBRIDGE HOSPITAL   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d MCLEAN HOSPITAL   (United States)

Author keywords

Adolescents; Choline; Depressive disorder; Frontal lobe; MRI; MRS

Indexed keywords

CHOLINE; CREATINE;

ADOLESCENT; AFFECTIVE NEUROSIS; ARTICLE; BRAIN LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; FEMALE; FRONTAL LOBE; GRAY MATTER; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE; ORBITAL CORTEX; PRIORITY JOURNAL; SCHOOL CHILD; SPECTROSCOPY; WHITE MATTER;

ADOLESCENT; ASPARTIC ACID; CASE-CONTROL STUDIES; CHOLINE; CREATINE; CYTOSOL; DEPRESSION; FEMALE; FRONTAL LOBE; HUMANS; INOSITOL; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; PSYCHIATRIC STATUS RATING SCALES; REGRESSION ANALYSIS; SEVERITY OF ILLNESS INDEX;

EID: 0034563665     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(00)00942-2     Document Type: Article

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