Arsenic induces peroxynitrite generation and cyclooxygenase-2 protein expression in aortic endothelial cells: Possible role in atherosclerosis

Toxicology and Applied Pharmacology

Volumn 184, Issue 1, 2002, Pages 11-18

  Bunderson, Melisa ^a   Coffin, J Douglas ^a   Beall, Howard D ^a  

^a UNIVERSITY OF MONTANA   (United States)

Author keywords

Arsenic; Arsenite; Atherosclerosis; Cyclooxygenase 2; Endothelial cells; Nitrotyrosine; Peroxynitrite; Prostaglandins

Indexed keywords

3 NITROTYROSINE; ANTIBODY; ARSENIC; CYCLOOXYGENASE 2; PEROXYNITRITE; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; AORTA; ARTICLE; ATHEROSCLEROSIS; CHEMICAL BINDING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORONARY ARTERY DISEASE; ENDOTHELIUM CELL; IMMUNOPRECIPITATION; NITRATION; NONHUMAN; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TIME;

BOVINAE;

EID: 0036408829     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-008X(02)99492-5     Document Type: Article

References (43)

1. Abernathy, C. O., Liu, Y. P., Longfellow, D., Aposhian, H. V., Beck, B., Fowler, B., Goyer, R., Menzer, R., Rossman, T., Thompson, C., and Waalkes, M. (1999). Arsenic: Health effects, mechanisms of actions, and research issues. Environ. Health Perspect. 107, 593-597.
2. Al-Mehdi, A. B., Shuman, H., and Fisher, A. B. (1997). Intracellular generation of reactive oxygen species during nonhypoxic lung ischemia. Am. J. Physiol. 272, L294-L300.
3. Barchowsky, A., Klei, L. R., Dudek, E. J., Swartz, H. M., and James, P. E. (1999). Stimulation of reactive oxygen, but not reactive nitrogen species, in vascular endothelial cells exposed to low levels of arsenite. Free Radical Biol. Med. 27, 1405-1412.
4. Beckman, J. S. (1996). Oxidative damage and tyrosine nitration from peroxynitrite. Chem. Res. Toxicol. 9, 836-844.
5. Beckman, J. S., and Koppenol, W. H. (1996). Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly. Am. J. Physiol. 271, C1424-C1437.
6. Beckmann, J. S., Ye, Y. Z., Anderson, P. G., Chen, J., Accavitti, M. A., Tarpey, M. M., and White, C. R. (1994). Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry. Biol. Chem. Hoppe Seyler 375, 81-88.
7. Boulos, C., Jiang, H., and Balazy, M. (2000). Diffusion of peroxynitrite into the human platelet inhibits cyclooxygenase via nitration of tyrosine residues. J. Pharmacol. Exp. Ther. 293, 222-229.
8. Buchet, J., and Lison, D. (2000). Clues and uncertainties in the risk assessment of arsenic in drinking water. Food Chem. Toxicol. 38, S81-S85.
9. Cheng, X. S., Shimokawa, H., Momii, H., Oyama, J., Fukuyama, N., Egashira, K., Nakazawa, H., and Takeshita, A. (1999). Role of superoxide anion in the pathogenesis of cytokine-induced myocardial dysfunction in dogs in vivo. Cardiovasc. Res. 42, 651-659.
10. Colville-Nash, P. R., and Gilroy, D. W. (2000). COX-2 and the cyclopentenone prostaglandins. A new chapter in the book of inflammation? Prostaglandins Other Lipid Mediat. 62, 33-43.
11. Crow, J. P., and Ischiropoulos, H. (1996). Detection and quantitation of nitrotyrosine residues in proteins: In vivo marker of peroxynitrite. Methods Enzymol. 269, 185-194.
12. Engel, R. R., and Smith, A. H. (1994). Arsenic in drinking water and mortality from vascular disease: An ecologic analysis in 30 counties in the United States. Arch. Environ. Health 49, 418-427.
13. Fang, X., Moore, A. S., Nwankwo, O. J., Weintraub, L. N., Oberley, W. L., Snyder, D. G., and Spector, A. A. (2000). Induction of cyclooxygenase-2 by overexpression of the human catalase gene in cerebral microvascular endothelial cells. J. Neurochem. 75, 614-623.
14. Fong, C. Y., Pang, L., Holland, E., and Knox, A. J. (2000). TGF-betal stimulates IL-8 release, COX-2 expression, and PGE(2) release in human airway smooth muscle cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 279, L201-L207.
15. Gerszten, R. E., Mach, F., Sauty, A., Rosenzweig, A., and Luster, A. D. (2000). Chemokines, leukocytes, and atherosclerosis. J. Lab. Clin. Med. 136, 87-92.
16. Gow, A. J., Duran, D., Malcolm, S., and Ischiropoulos, H. (1996). Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation. FEBS Lett. 385, 63-66.
17. Gurr, J. R., Liu, F., Lynn, S., and Jan, K. Y. (1998). Calcium-dependent nitric oxide production is involved in arsenite-induced micronuclei. Mutat. Res. 416, 137-148.
18. Ischiropoulos, H. (1998). Biological tyrosine nitration: A pathophysiological function of nitric oxide and reactive oxygen species. Arch. Biochem. Biophys. 356, 1-11.
19. Ishida, H., Ichimori, K., Hirota, Y., Fukahori, M., and Nakazawa, H. (1996). Peroxynitrite-induced cardiac myocyte injury. Free Radical Biol. Med. 20, 343-350.
20. Keaney, J. F., Jr. (2000). Atherosclerosis: From lesion formation to plaque activation and endothelial dysfunction. Mol. Aspects Med. 21, 99-166.
21. Kumagai, T., Kawamoto, Y., Nakamura, Y., Hatayama, I., Satoh, K., Osawa, T., and Uchida, K. (2000). 4-Hydroxy-2-nonenal, the end product of lipid peroxidation, is a specific inducer of cyclooxygenase-2 gene expression. Biochem. Biophys. Res. Commun. 273, 437-441.
22. Landino, L. M., Crews, B. C., Timmons, M. D., Morrow, J. D., and Marnett, L. J. (1996). Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis. Proc. Natl. Acad. Sci. USA 93, 15069-15074.
23. Leeuwenburgh, C., Hardy, M. M., Hazen, S. L., Wagner, P., Oh-ishi, S., Steinbrecher, U. P., and Heinecke, J. W. (1997).Reactive nitrogen intermediates promote low density lipoprotein oxidation in human atherosclerotic intima. J. Biol. Chem. 272, 1433-1436.
24. Lewis, D. R., Southwick, J. W., Hellstrom-Ouellet, R., Rench, J., and Calderon, R. L. (1999). Drinking water in arsenic in Utah: A cohort mortality study. Environ. Health Perspect. 107, 359-365.
25. Levonen, A. L., Patel, R. P., Brookes, P., Go, Y. M., Jo, H., Parthasarathy, S., Anderson, P. G., and Darley-Usmar, V. M. (2001). Mechanisms of cell signaling by nitric oxide and peroxynitrite: From mitochondria to MAP kinases. Antioxidant Redox Signal. 3, 215-229.
26. Lipsky, P. E., Brooks, P., Crofford, L. J., DuBois, R., Graham, D., Simon, L. S., van de Putte, L. B., and Abramson, S. B. (2000). Unresolved issues in the role of cyclooxygenase-2 in normal physiologic processes and disease. Arch. Intern. Med. 160, 913-920.
27. Liu, F., and Jan, K. Y. (2000). DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells. Free Radical Biol. Med. 28, 55-63.
28. Lusis, A. J. (2000). Atherosclerosis. Nature 407, 233-241.
29. Lynn, S., Gurr, J. R., Lai, H. T., and Jan, K. Y. (2000). NADH oxidase activation is involved in arsenite-induced oxidative DNA damage in human vascular smooth muscle cells. Circ. Res. 86, 514-519.
30. Marrogi, A., Pass, H. I., Khan, M., Metheny-Barlow, L. J., Harris, C. C., and Gerwin, B. I. (2000). Human mesothelioma samples overexpress both cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (NOS2): In vitro antiproliferative effects of a COX-2 inhibitor. Cancer Res. 60, 3696-3700.
31. Mosmann, T. (1983). Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63.
32. Nikolic, D., and van Breemen, R. B. (2001). DNA oxidation induced by cyclooxygenase-2. Chem. Res. Toxicol. 14, 351-354.
33. Ohnishi, K., Yoshida, H., Shigano, K., Nakamura, S., Fujisawa, S., Naito, K., Shinjo K., Fujita, Y., Matsul, H., Takeshita K., Sugiyama, S., Satoh, H., Terada, H., and Ohno, R. (2000). Prolongation of the QT interval and ventricular tachycardia in patients treated with arsenic trioxide for acute promyelocytic leukemia. Ann. Intern. Med. 133, 881-885.
34. Oyama, J., Shimokawa, H., Momii, H., Cheng, X., Fukuyama, N., Arai, Y., Egashira, K., Nakazawa, H., and Takeshita, A. (1998). Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo. J. Clin. Invest. 101, 2207-2214.
35. Saito, T., Rodger, I. W., Hu, F., Shennib, H., and Giaid, A. (2000). Inhibition of cyclooxygenase-2 improves cardiac function in myocardial infarction. Biochem. Biophys. Res. Commun. 273, 772-775.
36. Smith, K. R., Klei, L. R., and Barchowsky, A. (2001). Arsenite stimulates plasma membrane NADPH oxidase in vascular endothelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 280, L442-L449.
37. Smith, W. L., and DeWitt, D. L. (1996). Prostaglandin endoperoxide H synthases-1 and 2. Adv. Immunol. 62, 167-215.
38. Supinski, G., Nethery, D., Stofan, D., and DiMarco, A. (1999). Extracellular calcium modulates generation of reactive oxygen species by the contracting diaphragm. J. Appl. Physiol. 87, 2177-2185.
39. Tsai, S.-H., Liang, Y.-C., Chen, L., Ho, F.-M., Hsieh, M.-S., and Lin, J.-K. (2002). Arsenite stimulates cyclooxygenase-2 expression through activating IκB kinase and nuclear factor κB in primary and ECV304 endothelial cells. J. Cell. Biochem. 84, 750-758.
40. Tseng, C. H., Chong, C. K., Chen, C. J., Lin, B. J., and Tai, T. Y. (1995). Abnormal peripheral microcirculation in seemingly normal subjects living in Blackfoot-disease-hyperendemic villages in Taiwan. Int. J. Microcirc. 15, 21-27.
41. Tsujii, M., Kawano, S., Tsuji, S., Sawaoka, H., Hori, M., and DuBois, R. N. (1998). Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 93, 705-716.
42. Uppu, R. M., and Pryor, W. A. (1996). Synthesis of peroxynitrite in a two-phase system using isoamyl nitrite and hydrogen peroxide. Anal. Biochem. 236, 242-249.
43. van der Vliet, A., Smith, D., O'Neill, C. A., Kaur, H., Darley-Usmar, V., Cross, C. E., and Halliwell, B. (1994). Interactions of peroxynitrite with human plasma and its constituents: Oxidative damage and antioxidant depletion. Biochem. J. 303, 295-301.