4-Hydroxy-2-nonenal, the end product of lipid peroxidation, is a specific inducer of cyclooxygenase-2 gene expression

Biochemical and Biophysical Research Communications

Volumn 273, Issue 2, 2000, Pages 437-441

  Kumagai, Takeshi ^a   Kawamoto, Yoshiyuki ^a   Nakamura, Yoshimasa ^b   Hatayama, Ichiro ^c   Satoh, Kimihiko ^c   Osawa, Toshihiko ^a   Uchida, Koji ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c HIROSAKI UNIVERSITY   (Japan)

Author keywords

4 Hydroxy 2 nonenal; Cyclooxygenase 2; Lipid peroxidation; Oxidative stress; Prostaglandins

Indexed keywords

4 HYDROXYNONENAL; CYCLOOXYGENASE 2; LIPID PEROXIDE; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME INDUCTION; EPITHELIUM CELL; GENE INDUCTION; GLUTATHIONE METABOLISM; LIPID PEROXIDATION; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0033879516     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.2967     Document Type: Article

References (17)

1. Smith W. L., Garavito R. M., DeWitt D. L. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J. Biol. Chem. 271:1996;33157-33160.
2. Yamamoto K., Arakawa T., Ueda N., Yamamoto S. Transcriptional roles of nuclear factor κB and nuclear factor-interleukin-6 in the tumor necrosis factor α-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells. J. Biol. Chem. 270:1995;31315-31320.
3. Ryseck R. P., Raynoschek C., Macdonald-Bravo H., Dorfman K., Mattei M., Bravo R. Identification of an immediate early gene, pghs-B, whose protein product has prostaglandin synthase/cyclooxygenase activity. Cell Growth Differ. 3:1992;443-450.
4. Yamagata K., Andreasson K. I., Kaufmann W. E., Barnes C. A., Worley P. F. Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids. Neuron. 11:1993;371-386.
5. Halliwell B., Gutteridge J. M. C. Free Radicals in Biology and Medicine. 1989;Clarendon Press, Oxford.
6. Esterbauer H., Schauer R. J., Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes. Free Radicals Biol. Med. 11:1991;81-128.
7. Uchida K. Role of reactive aldehydes in cardiovascular diseases. Free Radicals Biol. Med. 2000.
8. Poli G., Albano E., Dianzani M. U. The role of lipid peroxidation in liver damage. Chem. Phys. Lipids. 45:1987;117-142.
9. Nanji A. N., Miao L. M., Thomas O., Rahemtulla A., Khwaja S., Zhao S., Peters D., Tahan S. R., Dannenberg A. J. Enhanced cyclooxygenase-2 gene expression in alcoholic liver disease in the rat. Gastroenterology. 112:1997;943-951.
10. Laemmuli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
11. Uchida K., Shiraishi M., Naito Y., Torii Y., Nakamura Y., Osawa T. Activation of stress signaling pathways by the end-product of lipid peroxidation: 4- Hydroxy-2-nonenal is a potential inducer of intracellular peroxide production. J. Biol. Chem. 274:1999;2234-2242.
12. Bandyopadhyay S., Gronostajski R. M. Identification of a conserved oxidation-sensitive cysteine residue in the NFI family of DNA-binding proteins. J. Biol. Chem. 269:1994;29949-29955.
13. Mitomo K., Nakayama K., Fujimoto K., Sun X., Seki S., Yamamoto K. Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-kappa B in vitro. Gene (Amst.). 145:1994;197-203.
14. Abate C., Patel L. F. J., Rauscher F. J. III, Curran T. Redox regulation of Fos and Jun DNA binding activity in vitro. Science. 249:1990;1157-1161.
15. Subbaramaiah K., Chung W. J., Michaluart P., Telang N., Tanabe T., Inoue H., Jang M., Pezzuto J. M., Dannenberg A. J. Resveratol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J. Biol. Chem. 273:1998;21875-21882.
16. Xie W., Herschman H. R. v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factor. J. Biol. Chem. 270:1995;27622-27628.
17. Reddy S. T., Wadleigh D. J., Herschman H. R. Transcriptional regulation of the cyclooxygenase-2 gene in activated mast cells. J. Biol. Chem. 275:2000;3107-3113.