메뉴 건너뛰기




Volumn 19, Issue 3, 2002, Pages 126-137

IL-12 plays a significant role in the apoptosis of human T cells in the absence of antigenic stimulation

Author keywords

Apoptosis; IL 12; T cells

Indexed keywords

ANTIGEN; CASPASE 2; CASPASE 3; CASPASE 7; DNA FRAGMENT; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; GAMMA INTERFERON; INTERLEUKIN 12; JANUS KINASE; MESSENGER RNA; PROTEIN; PROTEIN DFF45; PROTEIN TRADD; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

EID: 0036400483     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2002.1958     Document Type: Article
Times cited : (22)

References (36)
  • 1
    • 0024467154 scopus 로고    scopus 로고
    • Identification and purification of natural killer cell stimulatory factor, a cytokine with multiple biologic effects on human lymphocytes
    • Kobayashi ML, Fitz M, Ryan RM, Hewick SC, Clark S, Chan R, Loudon F, Sherman B, Trinchieri G (1998) Identification and purification of natural killer cell stimulatory factor, a cytokine with multiple biologic effects on human lymphocytes. J Exp Med 170:827-845.
    • (1998) J Exp Med , vol.170 , pp. 827-845
    • Kobayashi, M.L.1    Fitz, M.2    Ryan, R.M.3    Hewick, S.C.4    Clark, S.5    Chan, R.6    Loudon, F.7    Sherman, B.8    Trinchieri, G.9
  • 2
    • 0027336689 scopus 로고
    • Listeria-induced Th1 development in ab-TCR transgenic CD4+ T cells occurs through macrophage production of IL-12
    • Hsieh C, Macatonia SE, Tripp CS, Wolf SE, O'Garra A, Murphy KM (1993) Listeria-induced Th1 development in ab-TCR transgenic CD4+ T cells occurs through macrophage production of IL-12. Science 260:547-549.
    • (1993) Science , vol.260 , pp. 547-549
    • Hsieh, C.1    Macatonia, S.E.2    Tripp, C.S.3    Wolf, S.E.4    O'Garra, A.5    Murphy, K.M.6
  • 3
    • 0026441372 scopus 로고
    • Natural killer cell stimulatory factor or IL-12 has differential effects on proliferation of TCR-αβ+, TCR-γδ+ T lymphocytes, and NK cells
    • Perussia B, Chan SH, D'Andrea A, Tsuji K, Santoli D, Pospisil M (1992) Natural killer cell stimulatory factor or IL-12 has differential effects on proliferation of TCR-αβ+, TCR-γδ+ T lymphocytes, and NK cells. J Immunol 149:3495-3502.
    • (1992) J Immunol , vol.149 , pp. 3495-3502
    • Perussia, B.1    Chan, S.H.2    D'Andrea, A.3    Tsuji, K.4    Santoli, D.5    Pospisil, M.6
  • 4
    • 0028015923 scopus 로고
    • Induction mechanism of human blood CD8+ T cells proliferation and cytotoxicity by natural killer cell stimulatory factor
    • Nabioullin R, Sone S, Nii A, Haku T, Ogura T (1994) Induction mechanism of human blood CD8+ T cells proliferation and cytotoxicity by natural killer cell stimulatory factor. Jpn J Cancer Res 85(1994):853-861.
    • (1994) Jpn J Cancer Res , vol.85 , Issue.1994 , pp. 853-861
    • Nabioullin, R.1    Sone, S.2    Nii, A.3    Haku, T.4    Ogura, T.5
  • 5
    • 0029112641 scopus 로고
    • Cytotoxic effect of TNF and lymphotoxin on lymphoblasts
    • Sarin A, Conan-Cibotti M, Henkart PA (1995) Cytotoxic effect of TNF and lymphotoxin on lymphoblasts. J Immunol 155:3716-3718.
    • (1995) J Immunol , vol.155 , pp. 3716-3718
    • Sarin, A.1    Conan-Cibotti, M.2    Henkart, P.A.3
  • 6
    • 0031172517 scopus 로고    scopus 로고
    • Regulation of Fas and Fas-ligand expression in NK cells by cytokines and involvement of Fas-ligand in NK/LAK cells mediated cytotoxicity
    • Medvedev AE, Johnsen AC, Haux J, Steinkjer B, Egeberg K, Lynch DH, Sundan A, Espevik T (1997) Regulation of Fas and Fas-ligand expression in NK cells by cytokines and involvement of Fas-ligand in NK /LAK cells mediated cytotoxicity. Cytokine 9:394-404.
    • (1997) Cytokine , vol.9 , pp. 394-404
    • Medvedev, A.E.1    Johnsen, A.C.2    Haux, J.3    Steinkjer, B.4    Egeberg, K.5    Lynch, D.H.6    Sundan, A.7    Espevik, T.8
  • 7
    • 0032079469 scopus 로고    scopus 로고
    • IL-12 inhibits graft-versus host disease through a Fas-mediated mechanism associated with alterations in donor T cell activation and expansion
    • Dey BR, Yang YG, Szot GL, Pearson DA, Sykes M (1998) IL-12 inhibits graft-versus host disease through a Fas-mediated mechanism associated with alterations in donor T cell activation and expansion. Blood 91:3315-3322.
    • (1998) Blood , vol.91 , pp. 3315-3322
    • Dey, B.R.1    Yang, Y.G.2    Szot, G.L.3    Pearson, D.A.4    Sykes, M.5
  • 8
    • 0031840880 scopus 로고    scopus 로고
    • Apoptosis induced by NK cells is modulated by the NK active cytokines IL-2 and IL-12
    • Rodella L, Rezzani R, Zauli G, Mariani AR, Rizzoli R, Vitate M (1998) Apoptosis induced by NK cells is modulated by the NK active cytokines IL-2 and IL-12. Int Immunol 10:719-725.
    • (1998) Int Immunol , vol.10 , pp. 719-725
    • Rodella, L.1    Rezzani, R.2    Zauli, G.3    Mariani, A.R.4    Rizzoli, R.5    Vitate, M.6
  • 9
    • 0031594417 scopus 로고    scopus 로고
    • Failure of TGF beta1 and IL-12 to regulated human FasL and mTNF alloreactive cytotoxic T cell pathway
    • Asselin-Paturel C, Pardoux C, Gay F, Chouaid S (1998) Failure of TGF beta1 and IL-12 to regulated human FasL and mTNF alloreactive cytotoxic T cell pathway. Tissue Antigens 51:242-249.
    • (1998) Tissue Antigens , vol.51 , pp. 242-249
    • Asselin-Paturel, C.1    Pardoux, C.2    Gay, F.3    Chouaid, S.4
  • 10
    • 0028839280 scopus 로고
    • T helper tyoe1/T helper type 2 cytokines and T cell death: Preventive effect of IL-12 on activation induced and CD95 mediated apoptosis of CD4+ T cells from HIV infected persons
    • Estaquier J, Idziorek T, Zou W, Emilie D, Farber CM, Bourez JM, Ameisen JC (1995) T helper tyoe1/T helper type 2 cytokines and T cell death: preventive effect of IL-12 on activation induced and CD95 mediated apoptosis of CD4+ T cells from HIV Infected persons. J Exp Med 182:1759-1767.
    • (1995) J Exp Med , vol.182 , pp. 1759-1767
    • Estaquier, J.1    Idziorek, T.2    Zou, W.3    Emilie, D.4    Farber, C.M.5    Bourez, J.M.6    Ameisen, J.C.7
  • 11
    • 0032407211 scopus 로고    scopus 로고
    • Murine model of oral tolerance. Induction of Fas mediated apoptosis by blockade of IL-12
    • Marth T, Zeitz Z, Ludviksson B, Strober W, Kelsall B (1998) Murine model of oral tolerance. Induction of Fas mediated apoptosis by blockade of IL-12. Ann NY Acad Sci 859:290-294.
    • (1998) Ann NY Acad Sci , vol.859 , pp. 290-294
    • Marth, T.1    Zeitz, Z.2    Ludviksson, B.3    Strober, W.4    Kelsall, B.5
  • 12
    • 0028215682 scopus 로고
    • Marked apoptosis of human myelomonocytic leukemia cell line P39: Significance of cellular differentiation
    • Anzai N, Kawabata H, Hirama T, Masutani H, Ohmori M, Yoshida Y, Okuma M (1994) Marked apoptosis of human myelomonocytic leukemia cell line P39: significance of cellular differentiation. Leukemia 8:446-453.
    • (1994) Leukemia , vol.8 , pp. 446-453
    • Anzai, N.1    Kawabata, H.2    Hirama, T.3    Masutani, H.4    Ohmori, M.5    Yoshida, Y.6    Okuma, M.7
  • 13
    • 0025918157 scopus 로고
    • Role of cytokines in the differentiation of CD4+ T-cell subsets in vivo
    • Coffman RL, Varkila K, Scott P, Chatelain R (1991) Role of cytokines in the differentiation of CD4+ T-cell subsets in vivo. Immunol Rev 123:189-207.
    • (1991) Immunol Rev , vol.123 , pp. 189-207
    • Coffman, R.L.1    Varkila, K.2    Scott, P.3    Chatelain, R.4
  • 15
    • 0032555215 scopus 로고    scopus 로고
    • The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis
    • Liu X, Li P, Widlak P, Zou H, Luo X, Garrard WT, Wang X (1998) The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis. Proc Natl Acad Sci USA 21:8461-8466.
    • (1998) Proc Natl Acad Sci USA , vol.21 , pp. 8461-8466
    • Liu, X.1    Li, P.2    Widlak, P.3    Zou, H.4    Luo, X.5    Garrard, W.T.6    Wang, X.7
  • 17
    • 0030915095 scopus 로고    scopus 로고
    • Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis
    • Harvey NL, Butt AJ, Kumar S (1997) Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis. J Biol Chem 272(20):13134-13139.
    • (1997) J Biol Chem , vol.272 , Issue.20 , pp. 13134-13139
    • Harvey, N.L.1    Butt, A.J.2    Kumar, S.3
  • 19
    • 0033564668 scopus 로고    scopus 로고
    • Extinction of IL-12 signaling promotes Fas-mediated apoptosis of antigen-specific T cells
    • Marth T, Zeitz Z, Ludviksson B, Strober W, Kelsall B (1999) Extinction of IL-12 signaling promotes Fas-mediated apoptosis of antigen-specific T cells. J Immunol 162:7233-7240.
    • (1999) J Immunol , vol.162 , pp. 7233-7240
    • Marth, T.1    Zeitz, Z.2    Ludviksson, B.3    Strober, W.4    Kelsall, B.5
  • 21
    • 0032836832 scopus 로고    scopus 로고
    • Cytokines and apoptotic molecules in experimental melanin-protein induced uveitis (EMIU) and experimental autoimmune uveoretinitis
    • Li Q, Sun B, Matteson DM, O'Brien TP, Chan CC (1999) Cytokines and apoptotic molecules in experimental melanin-protein induced uveitis (EMIU) and experimental autoimmune uveoretinitis. Autoimmunity 30:171-182.
    • (1999) Autoimmunity , vol.30 , pp. 171-182
    • Li, Q.1    Sun, B.2    Matteson, D.M.3    O'Brien, T.P.4    Chan, C.C.5
  • 26
    • 0033537710 scopus 로고    scopus 로고
    • Inhibition of the Ca2+/calmodulin dependent protein kinase I cascade by cAMP dependent protein kinase
    • Matsushita M, Nairn AC (1999) Inhibition of the Ca2+/calmodulin dependent protein kinase I cascade by cAMP dependent protein kinase. J Biol Chem 274:10086-10093.
    • (1999) J Biol Chem , vol.274 , pp. 10086-10093
    • Matsushita, M.1    Nairn, A.C.2
  • 27
    • 0030447560 scopus 로고    scopus 로고
    • Signal transduction by interleukin 12 and interleukin 2
    • Bacon CM, Cho SS, O'Shea JJ (1996) Signal transduction by interleukin 12 and interleukin 2. Ann NY Acad Sci 857:41-59.
    • (1996) Ann NY Acad Sci , vol.857 , pp. 41-59
    • Bacon, C.M.1    Cho, S.S.2    O'Shea, J.J.3
  • 28
    • 0030046753 scopus 로고    scopus 로고
    • STATs: Signal transducers and activators of Transcription
    • Ihle JN (1996) STATs: signal transducers and activators of Transcription. Cell 84:331-334.
    • (1996) Cell , vol.84 , pp. 331-334
    • Ihle, J.N.1
  • 29
    • 0033563170 scopus 로고    scopus 로고
    • Tyrphostin B42 inhibits IL-12 induced tyrosine phosphorylation and activation of Janus Kinase-2 and prevents experimental allergic encephalomyelitis
    • Bright JJ, Du C, Sriram S (1999) Tyrphostin B42 inhibits IL-12 induced tyrosine phosphorylation and activation of Janus Kinase-2 and prevents experimental allergic encephalomyelitis. J Immunol 162:6255-6262.
    • (1999) J Immunol , vol.162 , pp. 6255-6262
    • Bright, J.J.1    Du, C.2    Sriram, S.3
  • 30
    • 0034691090 scopus 로고    scopus 로고
    • Crosstalk pathway for inhibition of glucocorticoid-induced apoptosis by T cells receptor signaling
    • Jamieson CA, Yamamoto KR (2000) Crosstalk pathway for inhibition of glucocorticoid-induced apoptosis by T cells receptor signaling. Proc Natl Acad Sci 97:7319-7324.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 7319-7324
    • Jamieson, C.A.1    Yamamoto, K.R.2
  • 31
    • 0029022365 scopus 로고
    • Involvement of an ICE-like protease in Fas-Mediated apoptosis
    • Enari M, Hug H, Nagata S (1995) Involvement of an ICE-like protease in Fas-Mediated apoptosis. Nature 375:78-81.
    • (1995) Nature , vol.375 , pp. 78-81
    • Enari, M.1    Hug, H.2    Nagata, S.3
  • 32
    • 0028805524 scopus 로고
    • Apoptosis by a cytosolic extract from Fas-activated cells
    • Enari M, Hase A, Nagata S (1995) Apoptosis by a cytosolic extract from Fas-activated cells. EMBO J 14:5201-5208.
    • (1995) EMBO J , vol.14 , pp. 5201-5208
    • Enari, M.1    Hase, A.2    Nagata, S.3
  • 34
    • 0028873964 scopus 로고
    • Fas and tumor necrosis factor induced apoptosis is inhibited by the poxvirus crmA gene product
    • Tewari M, Dixit VM (1995) Fas and tumor necrosis factor induced apoptosis is inhibited by the poxvirus crmA gene product. J Biol Chem 270:3255-3260.
    • (1995) J Biol Chem , vol.270 , pp. 3255-3260
    • Tewari, M.1    Dixit, V.M.2
  • 35
    • 0029978182 scopus 로고    scopus 로고
    • Sequential activation of ICE-like and CPP32 like proteases during Fas-mediated apoptosis
    • Enari M, Talanian RV, Wong WW, Nagata S (1996) Sequential activation of ICE-like and CPP32 like proteases during Fas-mediated apoptosis. Nature 380:723-726.
    • (1996) Nature , vol.380 , pp. 723-726
    • Enari, M.1    Talanian, R.V.2    Wong, W.W.3    Nagata, S.4
  • 36
    • 0033553481 scopus 로고    scopus 로고
    • Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease). Oligomerization and direct interaction with histone H1
    • Liu X, Zou H, Widlak P, Garrard W, Wang X (1999) Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease). Oligomerization and direct interaction with histone H1. J Biol Chem 274(20):13836-13840.
    • (1999) J Biol Chem , vol.274 , Issue.20 , pp. 13836-13840
    • Liu, X.1    Zou, H.2    Widlak, P.3    Garrard, W.4    Wang, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.