The RUNX1 Runt domain at 1.25 Å resolution: A structural switch and specifically bound chloride ions modulate DNA binding

Journal of Molecular Biology

Volumn 322, Issue 2, 2002, Pages 259-272

  Bäckström, Stefan ^a   Wolf Watz, Magnus ^b   Grundström, Christine ^a   Härd, Torleif ^b   Grundström, Thomas ^a   Sauer, Uwe H ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

Acute myeloid leukemia; Chloride binding; High resolution crystal structure; RUNX1 Runt DNA binding domain; Transcription regulation

Indexed keywords

AMINO ACID DERIVATIVE; CHLORIDE ION; CORE BINDING FACTOR; CORE BINDING FACTOR BETA; DNA; IMMUNOGLOBULIN G; PROTEIN; PROTEIN RUNT; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION (PARAMETERS); CRYSTAL STRUCTURE; ELECTROPHORETIC MOBILITY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM;

EUKARYOTA;

EID: 0036383150     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00702-7     Document Type: Article

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