Increase in interphotoreceptor matrix gelatinase A (MMP-2) associated with age-related macular degeneration

Experimental Eye Research

Volumn 67, Issue 6, 1998, Pages 637-645

  Plantner, J J ^a   Jiang, C ^a   Smine, A ^b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Age related macular degeneration; Gelatinase; Interphotoreceptor matrix; Metalloproteinases; Retina; Vitreous; Zymography

Indexed keywords

GELATINASE A; MATRIX METALLOPROTEINASE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ELECTROPHORESIS; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN TISSUE; MALE; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN CONTENT; RETINA MACULA AGE RELATED DEGENERATION; RETINA NEOVASCULARIZATION; VITREOUS BODY; ZYMOGRAPHY;

EID: 0032407594     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1998.0552     Document Type: Article

References (52)

1. Adler A. J., Severin K. M. Proteins of the bovine interphotoreceptor matrix: tissues of origin. Exp. Eye Res. 32:1981;755-769.
2. Alexander J. P., Bradley J. M., Gabourel J. D., Acott T. S. Expression of matrix metalloproteinases and inhibitor by human retinal pigment epithelium. Invest Ophthalmol. Vis. Sci. 31:1990;2520-2528.
3. Allikmets R., Shroyer N. F., Singh N., Seddon J. F., Lewis R. A., Bernstein P. S., Peiffer A., Zabriskie N. A., Li Y., Hutchinson A., Dean M., Lupski J. R., Leppert M. Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration. Science. 277:1997;1805-1807.
4. Azarian S. M., Travis G. H. The photoreceptor rim protein is an abc transporter encoded by the gene for recessive Stargardt's disease (ABCR). FEBS Lett. 409:1997;247-252.
5. Bird A. C., Bressler N. M., Bressler S. B., Chisholm I. H., Coscas G., Davis M. D., deJong P. T. V. M., Klaver C. C. W., Klein B. E. K., Klein R., Mitchell P., Sarks J. P., Sarks S. H., Soubrane G., Taylor H. R., Vingerling J. R. An international classification and grading system for age-related maculopathy and age-related macular degeneration. Surv. Ophthalmol. 39:1995;367-374.
6. Birkedal-Hansen H., Moore W. G. I., Bodden M. K., Windsor L. J., Birkedal-Hansen B., DeCarlo A., Engler J. A. Matrix metalloproteinases: A review. Crit. Rev. Oral Biol. Med. 4:1993;197-250.
7. Bressler N. M., Bressler S. B., Fine S. L. Age-related macular degeneration. Surv. Ophthalmol. 32:1988;375-413.
8. Brown D., Hamdi H., Bahri S., Kenney M. C. Characterization of an endogenous metalloproteinase in human vitreous. Curr. Eye Res. 13:1994;639-647.
9. Brown P. D., Kleiner D. E., Unsworth E. J., Stetler-Stevenson W. G. Cellular activation of the 72 kDa type IV procollagenase/TIMP-2 complex. Kidney Internat. 43:1993;163-170.
10. Campochiaro P. A., Jerdan J. A., Glaser B. M. The extracellular matrix of human retinal pigment epithelial cells in vivo and its synthesis in vitro. Invest. Ophthalmol. Vis. Sci. 27:1986;1615-1621.
11. Capon M. R. C., Marshall J., Krafft J. I., Alexander R. A., Hiscott P. S., Bird A. C. Sorsby's fundus dystrophy. A light and electron microscopic study. Ophthalmol. 96:1995;1769-1777.
12. Cingle K. A., Kalski R. S., Bruner W. E., O'Brien C. M., Erhard P., Wyszynski R. E. Age-related changes of glycosidases in human retinal pigment epithelium. Curr. Eye Res. 15:1996;433-438.
13. Davis M. D. Proliferative diabetic retinopathy. Retina. 1994;C. V. Mosby, St Louis. p. 1319-60.
14. De La Paz M. A., Pericak-Vance M. A., Lennon F., Haines J. L., Seddon J. M. Exclusion of TIMP3 as a candidate locus in age-related macular degeneration. Invest. Ophthalmol. Vis. Sci. 38:1997;1060-1065.
15. Elman M. J., Fine S. L. Exudative age-related macular degeneration. Ryan S. J. Retina. 1994;1103-1142 CV Mosby, St Louis.
16. Felbor U., Stohr H., Amann T., Schonherr U., Weber B. H. F. A novel ser165cys mutation in the tissue inhibitor of metalloproteinases-3 (TIMP3) in Sorsby's fundus dystrophy with unusual clinical features. Human Molec. Genet. 4:1995;2415-2416.
17. Frank R. N. Etiologic mechanisms in diabetic retinopathy. Ryan S. J. Retina. 1994;1243-1276 CV Mosby, St Louis.
18. Glaser B. M., Lemor M. Pathobiology of proliferative vitreoretinopathy. Ryan S. J. Retina. 1994;2249-2264 C. V. Mosby.
19. Greene J., Wang M., Liu Y. E., Raymond L. A., Rosen C., Shi Y. E. Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4. J. Biol. Chem. 271:1996;30375-30380.
20. Guyer D. R, Schachat A. P., Green W. R. The choroid: structural considerations. Ryan S. J. Retina. 1994;18-31 C. V. Mosby.
21. Hamilton W. K., Ewing C. C., Ives E. I., Carruthers J. D. Sorsby's fundus dystrophy. Ophthalmol. 96:1989;1755-1762.
22. Heussen C., Dowdle E. B. Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates. Anal. Biochem. 102:1980;196-202.
23. Hunt R. C., Fox A., Al Pakalnis V., Sigel M. M., Kosnosky W., Choudhury P., Black E. P. Cytokines cause cultured retinal pigment epithelial cells to secrete metalloproteinases and to contract collagen gels. Invest. Ophthalmol. Vis. Sci. 34:1993;3179-3186.
24. Illing M., Molday L. L., Molday R. S. The 220-kDa rim protein of retinal rod outer segments is a member of the abc transporter superfamily. J. Biol. Chem. 272:1997;10303-10310.
25. Kishnani N. S., Staskus P. W., Yang T.-T., Masiarz F. R., Hawkes S. P. Identification and characterization of human tissue inhibitor of metalloproteinase-3 and detection of three additional metalloproteinase inhibitor activities in extracellular matrix. Matrix Biol. 14:1994;479-488.
26. Klein R., Klein B. E. K., Linton K. L. P. Prevalence of age-related maculopathy. The Beaver Dam eye study. Ophthalmol. 99:1992;933-943.
27. Kleiner D. E., Stetler-Stevenson W. G. Quantitative zymography: detection of picogram quantities of gelatinases. Anal. Biochem. 218:1994;325-329.
28. Kolkenbrock H., Orgel D., Hecker-Kia A., Noack W., Ulbrich N. The complex between a tissue inhibitor of metalloproteinases (TIMP-2) and 72-kDa progelatinase is a metalloproteinase inhibitor. Eur. J. Biochem. 198:1991;775-781.
29. Kvanta A., Algvere P. V., Berglin L., Seregard S. Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor. Invest. Ophthalmol. Vis. Sci. 37:1996;1929-1934.
30. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227:1970;680-685.
31. Machemer R. Proliferative vitreoretinopathy (PVR): A personal account of its pathogenesis and treatment. Invest. Ophthalmol. Vis. Sci. 29:1988;1771-1783.
32. Matrisian L. M. The matrix-degrading metalloproteinases. BioEssays. 14:1992;455-463.
33. Mignatti P., Rifkin D. B. Plasminogen activators and matrix metalloproteinases in angiogenesis. Enzyme Prot. 49:1996;117-137.
34. Moses M. A. The regulation of neovascularization by matrix metalloproteinases and their inhibitors. Stem Cells. 15:1997;180-189.
35. Palmer E. A, Patz A, Phelps D. L., Spencer R. Retinopathy of prematurity. Ryan S. J. Retina. 1994;1473-1498 C. V. Mosby.
36. Papermaster D. S., Converse C. A., Zorn M. Biosynthetic and immunochemical characterization of a large protein in frog and cattle rod outer segment membranes. Exp. Eye Res. 23:1976;105-115.
37. Patz A. Studies on retinal neovascularization. Invest. Ophthalmol. Vis. Sci. 19:1980;1133-1138.
38. Plantner J. J. A microassay for proteolytic activity. Anal. Biochem. 195:1991a;129-131.
39. Plantner J. J. High molecular weight mucin-like glycoproteins of the bovine interphotoreceptor matrix. Exp. Eye Res. 54:1991b;113-125.
40. Plantner J. J. The presence of neutral metalloproteolytic activity and metalloproteinase inhibitors in the interphotoreceptor matrix. Curr. Eye Res. 11:1992;91-101.
41. Plantner J. J., Drew T. A. Polarized distribution of metalloproteinases in the bovine interphotoreceptor matrix. Exp. Eye Res. 59:1994;577-585.
42. Plantner J. J., Smine A., Quinn T. A. Matrix metalloproteinases in the interphotoreceptor matrix and vitreous. Curr. Eye Res. 17:1998;132-140.
43. Polkinghorne P. J., Capon M. R. C., Berninger T., Lyness A. L., Sehmi K., Bird A. C. Sorsby's fundus dystrophy. A clinical study. Ophthalmol. 96:1995;1763-1768.
44. Ray J. M., Stetler-Stevenson W. G. The role of matrix metalloproteinases and their inhibitors in tumor invasion, metastasis and angiogenesis. Eur. Respir. J. 7:1994;2062-2072.
45. Ryan S. J, Stout J. T., Dugel P. U. Subretinal neovascularization. Ryan S. J. Retina. 1994;1027-1048 C. V. Mosby.
46. Sato H., Kinoshita T., Takino T., Nakayama K., Seiki M. Activation of recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2. FEBS Lett. 393:1996;101-104.
47. Smine A., Plantner J. J. Membrane type-1 matrix metalloproteinase in ocular tissue. Curr. Eye Res. 16:1997;925-929.
48. Weber B. H. F., Vogt G., Pruett R. C., Stohr H., Felbor U. Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with sorsby's fundus dystrophy. Nature Genetics. 8:1994;352-356.
49. Will H., Hinzmann B. cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment. Eur. J. Biochem. 231:1995;602-608.
50. Woessner, Jr J. F. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 5:1991;2145-2154.
51. Wojtowicz-Praga S. M., Dickson R. B., Hawkins M. J. Matrix metalloproteinase inhibitors. Invest. New Drugs. 15:1997;61-75.
52. Young R. W. Pathophysiology of age-related macular degeneration. Surv. Ophthalmol. 31:1987;291-306.