Rapid determination of enantiomeric excess using infrared thermography

Organic Process Research and Development

Volumn 6, Issue 4, 2002, Pages 463-470

  Millot, Nicolas ^a   Borman, Phil ^a   Anson, Mike S ^a   Campbell, Ian B ^a   Macdonald, Simon J F ^a   Mahmoudian, Mahmoud ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DERIVATIVE; FUNGAL ENZYME; TRIACYLGLYCEROL LIPASE;

ACYLATION; ARTICLE; CANDIDA ANTARCTICA; CATALYST; ENANTIOMER; ENZYME SPECIFICITY; INFRARED PHOTOGRAPHY; MICROTITER PLATE ASSAY; NONHUMAN; STEREOCHEMISTRY; TECHNIQUE;

EID: 0036327589     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op010093k     Document Type: Article

References (30)

1. Enzymes for chemical synthesis
2. Industrial biocatalysis today and tomorrow
3. Practical considerations in kinetic resolution reactions
4. Combinatorial and evolution-based methods in the creation of enantioselective catalysts
5. Novel methods for biocatalyst screening
6. A scale-transparent reaction calorimetric assay for rapid catalyst screening
7. Combinatorial material science and catalysis
8. Reaction microarrays: A method for rapidly determining the enantiomeric excess of thousands of samples
9. A versatile periodate-coupled fluorogenic assay for hydrolytic enzymes
10. 2,15-Dihydroxyhexahelicene (HELIXOL): Synthesis and use as an enantioselective fluorescent sensor
11. A method for high-throughput screening of enantioselective catalysts
12. Super-high-throughput screening of enantioselective catalysts by using capillary array electrophoresis
13. Super high-throughput screening (SHTS) of chiral ligands and activators: Asymmetric activation of chiral diol-zinc catalysts by chiral nitrogen activators for the enantioselective addition of diethylzinc to aldehydes
14. Thermographic selection of effective catalysts from an encoded polymer-bound library
15. Development of infrared imaging to measure thermogenesis in cell culture: Thermogenic effects of uncoupling protein-2, troglitazone, and adrenoceptor agonists
16. Time-resolved IR-thermographic detection and screening of enantioselectivity in catalytic reactions
17. IR-thermographic screening of thermoneutral or endothermic transformations: The ring-closing olefin metathesis reaction
18. Catalyst screening using an array of thermistors
19. Calorimetric method for the monitoring and control of bioreactions
20. Investigation of catalytic properties of immobilized enzymes and cells by flow microcalorimetry
21. Reduction of carbonyl compounds with chiral oxazaborolidine catalysts: A new paradigm for enantioselective catalysis and a powerful new synthetic method
22. Detection of catalytic activity in combinatorial libraries of heterogeneous catalysts by IR thermography
23. Optisch aktive amine durch lipase-katalysierte methoxyacetylierung backenhohl
24. One biocatalyst - Many applications: The use of Candida antarctica B-lipase in organic synthesis