AMPA receptor-mediated miniature synaptic calcium transients in GluR2 null mice

Journal of Neurophysiology

Volumn 88, Issue 1, 2002, Pages 29-40

  Wang, Sabrina ^a   Jia, Zhengping ^a,b   Roder, John ^a,b   Murphy, Timothy H ^a,b,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR; CADMIUM CHLORIDE; CALCIUM CHANNEL; CALCIUM ION; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL CELL; ARTICLE; BRAIN CELL; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CONTROLLED STUDY; GLIA CELL; KNOCKOUT MOUSE; MOUSE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION;

EID: 0036314396     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2002.88.1.29     Document Type: Article

References (80)

1. Effects of a centrally active benzoylpyrrolidine drug on AMPA receptor kinetics
2. Effect of cyclothiazide on spontaneous miniature excitatory postsynaptic currents in rat hippocampal pyramidal cells
3. 2+ channels governing generation of miniature and evoked excitatory synaptic currents in spinal laminae I and II
4. Quantal amplitude and quantal variance of strontium-induced asynchronous EPSCs in rat dentate granule neurons
5. The GluR2 hypothesis: Ca(++)-permeable AMPA receptors in delayed neurodegeneration
6. Modulation of AMPA/kainate receptors by analogues of diazoxide and cyclothiazide in thin slices of rat hippocampus
7. Subunit composition at the single-cell level explains functional properties of a glutamate-gated channel
8. Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit
9. The glutamate receptor ion channels
10. Pentameric subunit stoichiometry of a neuronal glutamate receptor
11. Loose-patch recordings of single quanta at individual hippocampal synapses
12. Are some minis multiquantal?
13. Assembly of new individual excitatory synapses: Time course and temporal order of synaptic molecule recruitment
14. Selective reduction of GluR 2 protein in adult hippocampal CA3 neurons following status epilepticus but prior to cell loss
15. Distribution of glutamate and preproenkephalin messenger RNAs following transient focal cerebral ischemia
16. A receptor gene expression in adult rat hippocampus: An in situ hybridization study
17. 2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS
18. Postsynaptically silent synapses in single neuron cultures
19. 2+ influx in hippocampal CA1 neurons of gerbil
20. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
21. Calcium release-activated calcium current in rat mast cells
22. Identification of a site in glutamate receptor subunits that controls calcium permeability
23. Enhanced LTP in mice deficient in the AMPA receptor GluR 2
24. Molecular mechanisms controlling calcium entry through AMPA-type glutamate receptor channels
25. Immunogold localization of AMPA and NMDA receptors in somatic sensory cortex of albino rat
26. Calcium dynamics in single spines during coincident pre- and postsynaptic activity depend on relative timing of back-propagating action potentials and subthreshold excitatory postsynaptic potentials
27. NMDA receptor-mediated subthreshold Ca(2+) signals in spines of hippocampal neurons
28. Activation of silent synapses by rapid activity-dependent synaptic recruitment of AMPA receptors
29. Calcium in sympathetic boutons of rat superior cervical ganglion during facilitation, augmentation, and potentiation
30. Rapid, activation-induced redistribution of ionotropic glutamate receptors in cultured hippocampal neurons
31. An immunocytochemical assay for activity-dependent redistribution of glutamate receptors from the postsynaptic plasma membrane
32. Variability of neurotransmitter concentration and nonsaturation of postsynaptic AMPA receptors at synapses in hippocampal cultures and slices
33. Synaptic transmission at single visualized hippocampal boutons
34. Facilitation of spontaneous acetylcholine release induced by activation of cAMP in rat neuromuscular junctions
35. Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons
36. Vesicle number does not predict postsynaptic measures of miniature synaptic activity frequency in cultured cortical neurons
37. Ultrastructural correlates of quantal synaptic function at single CNS synapses
38. 2+ imaging of CNS axons in culture indicates reliable coupling between single action potentials and distal functional release sites
39. Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated
40. 2+ entry through the N-methyl-D-aspartate channel
41. A tetrameric subunit stoichiometry for a glutamate receptor-channel complex
42. Nonsaturation of AMPA and NMDA receptors at hippocampal synapses
43. 2+ permeability of AMPA-selective glutamate receptor channels
44. 2+ responses
45. Glutamate toxicity in immature cortical neurons precedes development of glutamate receptor currents
46. Mapping miniature synaptic currents to single synapses using calcium imaging reveals heterogeneity in postsynaptic output
47. Visualization of quantal synaptic transmission by dendritic calcium imaging
48. Heterogeneous release properties of visualized individual hippocampal synapses
49. Dynamics of dendritic calcium transients evoked by quantal release at excitatory hippocampal synapses
50. 2+ release evoked by metabotropic agonists and backpropagating action potentials in hippocampal CA1 pyramidal neurons
51. Voltage offests in patch-clamp experiments
52. Cyclothiazide differentially modulates desensitization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor splice variants
53. Structural determinants of allosteric regulation in alternatively spliced AMPA receptors
54. Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A
55. Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats
56. Glutamate receptor subunit 2-selective antibody shows a differential distribution of calcium-impermeable AMPA receptors among populations of neurons
57. 2+ transients in dendritic spines of hippocampal pyramidal neurons in brain slice
58. Alterations of the GluR-B AMPA receptor subunit flip/flop expression in kainate-induced epilepsy and ischemia
59. Correlation of miniature synaptic activity and evoked release probability in cultures of cortical neurons
60. NMDA receptor content of synapses in stratum radiatum of the hippocampal CA1 area
61. A fluorescent indicator for measuring cytosolic-free magnesium
62. A developmental switch in neurotransmitter flux enhances synaptic efficacy by affecting AMPA receptor activation
63. Ca(2+)-permeable AMPA receptors and spontaneous presynaptic transmitter release at developing excitatory spinal synapses
64. The tetrameric structure of a glutamate receptor channel
65. Analysis of calcium channels in single spines using optical fluctuation analysis
66. The role of RNA editing in controlling glutamate receptor channel properties
67. Morphological alterations in dendritic spines of rat hippocampal neurons exposed to N-methyl-D-aspartate
68. Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation
69. In vivo dendritic calcium dynamics in neocortical pyramidal neurons
70. Different modes of expression of AMPA and NMDA receptors in hippocampal synapses
71. Saturation of postsynaptic glutamate receptors after quantal release of transmitter
72. A calcium-dependent feedback mechanism participates in shaping single NMDA miniature EPSCs
73. Behaviour of NMDA and AMPA receptor-mediated miniature EPSCs at rat cortical neuron synapses identified by calcium imaging
74. Modulation of excitatory synaptic transmission by drugs that reduce desensitization at AMPA/kainate receptors
75. Activity coregulates quantal AMPA and NMDA currents at neocortical synapses
76. Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons
77. Dendritic localization of Ca(2+)-permeable AMPA/kainate channels in hippocampal pyramidal neurons
78. Dendritic spines as basic functional units of neuronal integration
79. Mechanisms of calcium influx into hippocampal spines: Heterogeneity among spines, coincidence detection by NMDA receptors, and optical quantal analysis
80. Biophysical model of a Hebbian synapse