Crystal and solution structures of an HslUV protease-chaperone complex

Cell

Volumn 103, Issue 4, 2000, Pages 633-643

  Sousa, Marcelo C ^a   Trame, Christine B ^a   Tsuruta, Hiro ^b   Wilbanks, Sigurd M ^a   Reddy, Vijay S ^c   McKay, David B ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; PROTEINASE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; HAEMOPHILUS INFLUENZAE; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; RADIATION SCATTERING;

HAEMOPHILUS INFLUENZAE; PROKARYOTA;

EID: 0033681249     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)00166-5     Document Type: Article

References (45)

1. The Pfam protein families database
2. Crystal structure of heat shock locus V (HslV) from Escherichia coli
3. The structures of HslU and the ATP-dependent protease HslU-HslV
4. Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors
5. Crystallography and NMR system: A new software suite for macromolecular structure determination
6. Sequence analysis of four new heat-shock genes constituting the hslTS/ibpAB and hslVU operons in Escherichia coli
7. An extensively modified version of MolScript that includes greatly enhanced coloring capabilities
8. Further additions to MolScript version 1.4, including reading and contouring of electron-density maps
9. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd
10. The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system
11. Structure of 20S proteasome from yeast at 2.4 A resolution
12. Protein binding and unfolding by the chaperone ClpA and degradation by the protease ClpAP
13. Proteolytic activity of the ATP-dependent protease HslVU can be uncoupled from ATP hydrolysis
14. A graphics model building and refinement system for macromolecules
15. The ATP-dependent HslVU/ClpQY protease participates in turnover of cell division inhibitor SulA in Eschedchia coli
16. Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA
17. Six-fold rotational symmetry of ClpQ, the E. coli homolog of the 20S proteasome, and its ATP-dependent activator, ClpY
18. Dynamics of substrate denaturation and translocation by the ClpXP degradation machine
19. Not your average density
20. A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication
21. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
22. Crystal structure of the hexamerization domain of N-ethylmaleimidesensitive fusion protein
23. Disassembly of the Mu transposase tetramer by the ClpX chaperone
24. Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution
25. Raster3D. Photorealistic molecular graphics
26. Identification and characterization of HsIV HsIU (ClpQ ClpY) proteins involved in overall proteolysis of misfolded proteins in Escherichia coli
27. AMoRe: An automated package for molecular replacement
28. AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes
29. HsIV-HsIU: A novel ATP-dependent protease complex in Escherichia coil related to the eukaryotic proteasome
30. The ATP-dependent HsIVU protease from Escherichia coli is a four-ring structure resembling the proteasome
31. HSP100/Clp proteins: A common mechanism explains diverse functions
32. Proteasome from Thermoplasma acidophilum: A threonine protease
33. GNOM - A program package for small-angle scattering data processing
34. The heat-shock protein HslVU from Escherichia coli is a protein-activated ATPase as well as an ATP-dependent proteinase
35. ATP-dependent degradation of SulA, a cell division inhibitor, by the HslVU protease in Escherichia coli
36. Unfolding and internalization of proteins by the ATP-dependent proteases ClpXP and ClpAP
37. Use of T7 RNA polymerase to direct expression of cloned genes
38. Mathematical methods in small-angle scattering data analysis
39. Crysol: A program to evaluate X-ray solution scattering of biological macromolecules from atomic coordinates
40. Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
41. Global unfolding of a substrate protein by the Hsp100 chaperone ClpA
42. Solution small-angle X-ray scattering study of the molecular chaperone Hsc70 and its subfragments
43. Purification and characterization of the heat shock proteins HslV and HslU that form a new ATP-dependent protease in Escherichia coli
44. ATP binding, but not its hydrolysis, is required for assembly and proteolytic activity of the HslVU protease in Escherichia coli
45. Structure of the ATP-dependent oligomerization domain of N-ethylmaleimide sensitive factor complexed with ATP