Gelatin-based resorbable sponge as a carrier matrix for human mesenchymal stem cells in cartilage regeneration therapy

Journal of Biomedical Materials Research

Volumn 52, Issue 2, 2000, Pages 246-255

  Ponticiello, Michael S ^a   Schinagl, Robert M ^a   Kadiyala, Sudha ^a   Barry, Frank P ^a  

^a OSIRIS THERAPEUTICS INC   (United States)

Author keywords

Biomatrix; Cartilage regeneration; Chondrogenesis; Mesenchymal stem cell; Resorbable gelatin sponge

Indexed keywords

BIOMEDICAL ENGINEERING; CARTILAGE; CELL CULTURE; COLLAGEN; IMMUNOLOGY; IMPLANTS (SURGICAL);

BIOMATRIX; CARRIER MATRIX; CARTILAGE REGENERATION THERAPY; CHONDROGENESIS; GELATIN BASED RESORBABLE SPONGE; HUMAN MESENCHYMAL STEM CELLS;

CELLS;

COLLAGEN TYPE 2; GELFOAM; GLYCOSAMINOGLYCAN POLYSULFATE; TRANSFORMING GROWTH FACTOR BETA3;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BONE DEFECT; CHONDROGENESIS; EXTRACELLULAR MATRIX; FEMUR CONDYLE; HUMAN; HUMAN CELL; LYMPHOCYTIC INFILTRATION; MESENCHYME CELL; NONHUMAN; RABBIT;

ADULT; ANIMALS; BIOCOMPATIBLE MATERIALS; CARTILAGE; CHONDROGENESIS; GELATIN SPONGE, ABSORBABLE; HUMANS; MESODERM; RABBITS; REGENERATION; STEM CELLS;

EID: 0034333644     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4636(200011)52:2<246::AID-JBM2>3.0.CO;2-W     Document Type: Article

References (42)

1. Repair of partial-thickness defects in articular cartilage: Cell recruitment from the synovial membrane
2. Treatment of osteochondritis dissecans of the talus: Use of the mosaicplasty technique - A preliminary report
3. Arthroscopic autogenous osteochondral mosaicplasty for the treatment of femoral condylar articular defects. A preliminary report
4. Osteochondral mosaicplasty for the treatment of focal chondral and osteochondral lesions of the knee and talus in the athlete. Rationale, indications, techniques, and results
5. Microfracture technique for full-thickness chondral defects: Technique and clinical results
6. Durability of regenerated articular cartilage produced by free autogenous periosteal grafts in major full-thickness defects in joint surfaces under the influence of continuous passive motion. A follow-up report at one year
7. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation
8. Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage
9. Repair of articular cartilage defects using mesenchymal stem cells
10. Culture-expanded human periosteal-derived cells exhibit osteochondral potential in vivo
11. Concepts of osteoblast growth and differentiation: Basis for modulation of bone cell development and tissue formation
12. Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone derived clonal cell population: Effect of dexamethasone
13. Modulation of commitment, proliferation, and differentiation of chondrogenic cells in defined culture medium
14. Use of mesenchymal stem cells in a collagen matrix for Achilles tendon repair
15. Multilineage potential of adult human mesenchymal stem cells
16. Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow
17. In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells
18. Human and animal mesenchymal progenitor cells from bone marrow: Identification of serum for optimal selection and proliferation
19. Monoclonal antibodies reactive with human osteogenic cell surface antigens
20. Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies
21. Phenotypic and functional comparison of cultures of mar-row-derived mesenchymal stem cells (MSCs) and stromal cells
22. Articular cartilage repair. Rabbit experiments with a collagen gel-biomatrix and chondrocytes cultured in it
23. Chondrocyte-seeded collagen matrices implanted in a chondral defect in a canine model
24. Cartilage reconstruction in head and neck surgery: Comparison of resorbable polymer scaffolds for tissue engineering of human septal cartilage
25. Poly(L-lactic acid) foams with cell seeding and controlled-release capacity
26. Neocartilage formation in vitro and in vivo using cells cultured on synthetic biodegradable polymers
27. Chondrogenesis in a cell-polymer-bioreactor system
28. Hyaluronic acid-based polymers as cell carriers for tissue-engineered repair of bone and cartilage
29. Cartilage tissue engineering with novel nonwoven structured biomaterial based on hyaluronic acid benzyl ester
30. A comparison of the biocompatibility of three absorbable hemostatic agents in the rat middle ear
31. Osseous regeneration in the presence of four common hemostatic agents
32. Comparison of ossification of demineralized bone, hydroxyapatite, Gelfoam, and bone wax in cranial defect repair
33. Bone formation and reosseointegration in peri-implantitis defects following surgical implantation of rhBMP-2
34. Tibial segmental defect repair: Chondrogenesis and biomechanical strength modulated by basic fibroblast growth factor
35. The growth of chondrocytes using Gelfoam as a biodegradable scaffold
36. A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures
37. Quantitative immunoassays for type-II collagen and its cyanogen bromide peptides
38. Modified Mallory aniline blue stain for bone, cartilage, and other connective tissues
39. In vitro differentiation of chick embryo bone marrow stromal cells into cartilaginous and bone-like tissues
40. Osteochondrogenic potential of marrow mesenchymal progenitor cells exposed to TGF-beta 1 or PDGF-BB as assayed in vivo and in vitro
41. Culture expanded canine mesenchymal stem cells possess osteochondrogenic potential in vivo and in vitro
42. Osteochondral progenitor cells in acute and chronic canine nonunions