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Volumn 10, Issue 8, 2002, Pages 2461-2470

6-Carboxy-5,7-diarylcyclopenteno[1,2-b]pyridine derivatives: A novel class of endothelin receptor antagonists

(16) Niiyama, Kenji a Mase, Toshiaki a Takahashi, Hirobumi a Naya, Akira a Katsuki, Kasumi a Nagase, Toshio a Ito, Satoshi a Hayama, Takashi a Hisaka, Akihiro a Ozaki, Satoshi a Ihara, Masaki a Yano, Mitsuo a Fukuroda, Takahiro a Noguchi, Kazuhito a Nishikibe, Masaru a Ishikawa, Kiyofumi a

a BANYU PHARMACEUTICAL CO LTD (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

6 CARBOXY 5 (2 METHOXYPHENYL) 7 (4 METHOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 5 (3 METHOXYPHENYL) 7 (4 METHOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 5 (3,4 METHYLENEDIOXYPHENYL) 7 PHENYLCYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 5 (4 METHOXYPHENYL) 7 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 5 (4 METHOXYPHENYL) 7 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 C]PYRIDINE; 6 CARBOXY 5 (INDOL 4 YL) 7 (4 METHOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 5 (INDOL 6 YL) 7 (4 METHOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 5,7 BIS(4 METHOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 7 (2 CARBOXYMETHOXY 4 METHOXYPHENYL) 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 7 (2 HYDROXY 4 METHOXYPHENYL) 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 7 (4 FLUOROPHENYL) 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 7 (4 HYDROXYPHENYL) 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 7 (4 METHOXYPHENYL) 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 7 (4 METHOXYPHENYL) 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 C]PYRIDINE; 6 CARBOXY 7 (4 METHOXYPHENYL) 5 PHENYLCYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 7 [2 (2 CARBOXYETHENYL) 4 METHOXYPHENYL] 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 7 [2 (2 CARBOXYETHYL) 4 METHOXYPHENYL] 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 7 [2 (2 HYDROXYETHOXY) 4 METHOXYPHENYL] 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 6 CARBOXY 7 [2 [2 (METHYLAMINO)ETHOXY] 4 METHOXYPHENYL] 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; 7 (2 CARBAMOYLMETHOXY 4 METHOXYPHENYL) 6 CARBOXY 5 (3,4 METHYLENEDIOXYPHENYL)CYCLOPENTENO[1,2 B]PYRIDINE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; FUNCTIONAL GROUP; INDAN DERIVATIVE; IODINE 125; PHENYL GROUP; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; ENDOTHELIN RECEPTOR; RADIOACTIVE IODINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; ISOTOPE LABELING; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PHYSICAL CHEMISTRY; RAT; RECEPTOR AFFINITY; RECEPTOR BLOCKING; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; ANIMAL; DRUG ANTAGONISM; ILIAC ARTERY; INTESTINE ABSORPTION; RABBIT; SURVIVAL RATE; SYNTHESIS;

ANIMALS; HUMANS; ILIAC ARTERY; INHIBITORY CONCENTRATION 50; INTESTINAL ABSORPTION; IODINE RADIOISOTOPES; MICE; PYRIDINES; RABBITS; RATS; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; STRUCTURE-ACTIVITY RELATIONSHIP; SURVIVAL RATE;

EID: 0036285750 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(02)00122-0 Document Type: Article

Times cited : (15)

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